XLOC_033095 (sec61a1l)


Basic Information

Item Value
gene id XLOC_033095
gene name sec61a1l
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007117.7
NCBI id CM002890.2
chromosome length 60270059
location 42377911 ~ 42388608 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00064309
TTTGTGCTCTTGGCGATGACGTGTCCTGAACACGCTACTATAGCTGATACCCGGTGCTCGCTAACCGCTAGTCTACGACCATCATCAGAGGGACACCATGGCCATTAAATTCTTGGAAGTAATAAAACCATTCTGTGCGGTTTTACCCGAGATCCAGAAGCCTGAGAGGAGGATTCAGTTCAAAGAAAAGGTGTTATGGACTGCGATCACTCTTTTCATCTTTCTGGTTTGCTGCCAGATTCCTCTTTTTGGAATCATGTCTTCGGACTCAGCAGATCCCTTTTATTGGATGAGAGTGATCATGGCATCCAACAGAGGTACTTTGATGGAGTTGGGTATCTCTCCCATTGTGACGTCTGGCCTGATCATGCAGCTGTTGGCTGGAGCTAAGATCATTGAGGTTGGAGACACCCCTAAAGACAGAGCGCTCTTTAATGGGGCTCAGAAACTGTTTGGCATGATCATCACCATTGGTCAGGCTATCGTTTATGTGATGACTGGTATGTATGGAGATCCTTCAGAGATGGGTGCTGGAATCTGCCTTCTCATTATCATCCAGTTGTTTGTAGCCGGTCTGATCGTGTTGCTGCTGGATGAGTTACTCCAAAAGGGCTATGGATTGGGCTCTGGTATCTCTCTCTTCATCGCCACCAACATCTGTGAGACAATCGTATGGAAGGCATTCAGCCcaacaacagtcaacacaggaagAGGCACGGAGTTTGAAGGAGCCATCATTGCTCTCTTTCACCTATTGGCCACTCGTACTGATAAAGTGCGAGCTCTAAGAGAAGCCTTTTACAGACAGAACCTGCCCAACCTCATGAACCTCATCGCTACAATCTTCGTCTTTGCTGTGGTCATATACTTCCAGGGATTTAGAGTCGATCTGCCCATCAAATCTGCACGTTACCGTGGCCAGTACAACACCTATCCCATCAAGCTCTTCTACACCTCCAACATTCCCATCATCCTGCAGTCTGCACTGGTGTCCAATCTTTACGTCATCTCTCAAATGCTCTCAACTCGCTTCAGTGGAAACTTCCTGGTCAACCTTTTGGGGACTTGGTCGGATACCTCAACTGGAGGACCGGCTCGTGCTTACCCAGTAGGTGGCCTTTGCTACTACCTCTCACCCCCAGAGTCCTTTGGCACAGTTCTGGAGGATCCAATCCATGCCATCATCTACATCATCTTCATGCTGGGATCGTGTGCCTTCTTCTCAAAGACCTGGATTGAAGTTTCCGGATCATCTGCCAAAGATGTTGCCAAACAGCTTAAAGAACAGCAGATGGTAATGAGAGGACACAGAGAAACATCAATGGTCCATGAACTGAACAGGTACATCCCTACAGCGGCAGCCTTCGGAGGCCTGTGTATAGGCGGTCTCTCAGTCATGGCTGACTTTCTGGGAGCCATCGGATCAGGAACTGGAATTTTGTTGGCCGTCACTATCATCTACCAGTACTTTGAGATCTTTGTGAAGGAACAGAGCGAAGTGGGCAGTGTGGGAGCTCTCCTGTTCTAGTATCGCCTTCTAACTGACTGAATTTTGAGTTTAATAAtttcttttatatgttttttgtttttgttttatttaacgcGCACATTCAGTGTTCTGCATCAAGGATGTGCTCCCATTGTGCATCTGATCCTGATCTGTACCAACTCGCTTCACACCAGAGCAGCAGACTGAAATGCATTTGGTTTTCTTGGGCGGGGGAAATATGGCAGCTTGATATCTCAGTGTTAGGCATGGGAATGTAACCATCCTTATTTTCCACCGTCTTCGTTTTCCGATAAAGGATCTATCAATTGTGTTTTTGATTTCAGGTAATTTCAATAACGCGAAAGAGAACAAGCATCCACGTTTAGGATCATTTGGACATCAgcttgtctctgtgtgtgtgtgtgtgtgtgtgtgtgatgacgtAAGTGCAATGATATATCATGGTAAAAGTCGATCTGGTGTAAATGATATGATTTTTATGATGTATGAGTGGAGAAGTGCAAATTTGCTTGCGTTTTGTGTGGGCTGAgtgtatgaaaacatttaaataggcTGTTAAAGTTCACCCAGGTGCATCAGCGCTGTTTCCTTTTTGCATTGGGTTTGAGGTTTTGCcgtttatatttatgtttgttgtttTCGTCTCAGAGCTTCAAGCTATTATGAAATGGATCTGTGCATTTTCAGTCGCACTACTTCAAATGTTTCTGTTATTGCACCTTTTTTAGTTCTATGTTGCTGTAGTTTCTTTCAGTGGACCAAATGCTGCAGAAACTGCCTGTTAATGATTATGCCAGTGTTGATAAGAGAGGAAGTGGTTTGTAAAAGAcgagtgtttgtgtgttgttttctTAAACATCACAGtattaaaatgtgcaaaaaaaatgtgtaaaaggaTACATTTGGAGATTTGTTCTTTGTACTTTTTGAGCACAATTTTAATATTGTCTAATGTTATTTAAAGGTAAAAGACTGTTACTTTAGTCTTAAGAATGAATCCCCACAATTGCCACAttcaatgaataaatacaaaaataagtcCA
>TCONS_00064310
GCAAATTCTATAAATTCAATTGTatttaaaacagaataaatatttaaattagaagTAGATATTAAATAGAATTATTGGGGTTCTGTATTATAAATCAATACACAACAGTCCAAAGTCTAAAATTAAATCTCATCAAGGactaaattagtaaaaaaaaaattaatgtttgtGACTAAATGAAACGCTTTACTTGCCAGTTGGTCATACTTTTTTCATCGTGATTCTGTCTACACTAAATACAGCATTAAATAATACCCTGATTTCTATTCACGAAAATACAGTTGTCTTGGGTATTGCTCACAAACTGCTCAACGTAACTAGGCTTCATATATATACTTTGCATTATTTAGGTTGCCAAACAGCTTAAAGAACAGCAGATGGTAATGAGAGGACACAGAGAAACATCAATGGTCCATGAACTGAACAGGTACATCCCTACAGCGGCAGCCTTCGGAGGCCTGTGTATAGGCGGTCTCTCAGTCATGGCTGACTTTCTGGGAGCCATCGGATCAGGAACTGGAATTTTGTTGGCCGTCACTATCATCTACCAGTACTTTGAGATCTTTGTGAAGGAACAGAGCGAAGTGGGCAGTGTGGGAGCTCTCCTGTTCTAGTATCGCCTTCTAACTGACTGAATTTTGAGTTTAATAAtttcttttatatgttttttgtttttgttttatttaa

Function

symbol description
sec61a1l Predicted to enable protein transmembrane transporter activity; ribosome binding activity; and signal sequence binding activity. Acts upstream of or within pronephros development. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Predicted to be part of Sec61 translocon complex. Is expressed in several structures, including EVL; anterior axial hypoblast; axis; ectoderm; and mesoderm. Human ortholog(s) of this gene implicated in familial juvenile hyperuricemic nephropathy. Orthologous to human SEC61A1 (SEC61 translocon subunit alpha 1).

GO:

id name namespace
GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation biological_process
GO:0048793 pronephros development biological_process
GO:0015031 protein transport biological_process
GO:0031204 posttranslational protein targeting to membrane, translocation biological_process
GO:0005783 endoplasmic reticulum cellular_component
GO:0005784 Sec61 translocon complex cellular_component
GO:0005789 endoplasmic reticulum membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0005048 signal sequence binding molecular_function
GO:0043022 ribosome binding molecular_function
GO:0008320 protein transmembrane transporter activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-021016-2 Predicted to enable protein transmembrane transporter activity; ribosome binding activity; and signal sequence binding activity. Acts upstream of or within pronephros development. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Predicted to be part of Sec61 translocon complex. Is expressed in several structures, including EVL; anterior axial hypoblast; axis; ectoderm; and mesoderm. Human ortholog(s) of this gene implicated in familial juvenile hyperuricemic nephropathy. Orthologous to human SEC61A1 (SEC61 translocon subunit alpha 1).

Ensembl:

ensembl_id ENSDARG00000005675

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00064309 False 2553 mRNA 0.43 12 42377911 42388608
TCONS_00064310 True 687 lncRNA 0.35 2 42378863 42379632

Neighbor

gene id symbol gene type direction distance location
XLOC_033094 emc3 coding downstream 604 42369999 ~ 42377307 (-)
XLOC_033093 usp4 coding downstream 8725 42345005 ~ 42369186 (-)
XLOC_033092 fancd2 coding downstream 40916 42291308 ~ 42336995 (-)
XLOC_033091 tex264a coding downstream 87652 42145626 ~ 42290259 (-)
XLOC_033090 grm2a coding downstream 265720 42051480 ~ 42112191 (-)
XLOC_033096 ip6k2a coding upstream 20474 42409082 ~ 42418225 (-)
XLOC_033097 edem1 coding upstream 544149 42932757 ~ 42949184 (-)
XLOC_033098 arl8ba coding upstream 563352 42951960 ~ 42971184 (-)
XLOC_033099 tnfrsf18 coding upstream 586670 42975278 ~ 42983843 (-)
XLOC_033100 si:ch73-361p23.3 coding upstream 613356 43001964 ~ 43007264 (-)
XLOC_033085 NA non-coding downstream 925023 41451670 ~ 41452888 (-)
XLOC_033077 NA non-coding downstream 1409570 40963686 ~ 40968341 (-)
XLOC_033076 CR293534.1 non-coding downstream 1431436 40946357 ~ 40946475 (-)
XLOC_033074 NA non-coding downstream 1513833 40856139 ~ 40864078 (-)
XLOC_033070 CR450814.1 non-coding downstream 1558145 40795898 ~ 40819766 (-)
XLOC_033102 NA non-coding upstream 668854 43057462 ~ 43072882 (-)
XLOC_033106 BX927362.1 non-coding upstream 958321 43346929 ~ 43349086 (-)
XLOC_033111 NA non-coding upstream 1591103 43979711 ~ 44002542 (-)
XLOC_033118 NA non-coding upstream 3535334 45923942 ~ 45929175 (-)
XLOC_033121 BX005101.1 non-coding upstream 3779409 46168017 ~ 46251940 (-)

Expression


Co-expression Network