XLOC_033126 (kcnb1)



Basic Information


Item Value
gene id XLOC_033126
gene name kcnb1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007117.7
NCBI id CM002890.2
chromosome length 60270059
location 46507609 ~ 46565466 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00064377
atgGAGAAACCCTCGGCAGGAATGAGTAAAGTTGGCTCTCGCTCGACAGCCTCTCTGCCCCCGGAGCCTGTGGATATAATCCGGAGTATGTCCTGCTACCGGCGTGTCAAACTGAACGTAGGTGGTCTGCCGCATGAGGTCCTGTGGAGAACCCTGGACCGACTGCCGCGCACGCGACTGGGCAAGCTGCGAGACTGCAAAACCCACGAATCCCTCATGGAAGTATGTGACGACTACAACCTGGAGGACAACGAGTACTTTTTTGACCGGCATCCCGGGGCCTTCACTTCCATACTGAACTTCTACCGCACTGGGAAGCTGCACATGATGGAGGAGATGTGCGCCCTGTCCTTCAGCCAGGAGCTGGACTACTGGGGAGTGGATGAGATCTACTTGGAGTCGTGCTGCCAGGCCAGATACCATCAAAAGAAGGAGCAGATGAACGAGGAGCTCAAGCGAGAAGCTGATACGCTGAAGGACCGAGAGGGTGAAGAATTCGATAATACGTGTTGTTCGGAGAAAAGGAAGAAATTATGGGATCTACTGGAGAAACCGGGATCGTCTGTAGCAGCCAAGATCTTGGCCATCATATCAATCCTATTCATCGTGCTCTCCACTATCGCTTTGTCTCTCAACACTCTCCCGGAACTTCAAGAAACAGACGAATTTGGTCAAACTACTGATAATACCCAGCTGGCTCACGTGGAGGCAGTGTGCATTGCTTGGTTCACCATGGAATATCTTCTTCGCTTCCTTTCCTCACCAAACAAATGGAAATTCTTTAAAGGTCCTCTTAATGTCATCGACCTGCTTGCCATCCTACCATATTATGTCACCATATTCTTGACAGAGTCCAACAAAAGTGTACTGCAATTCCAGAATGTAAGACGGGTGGTGCAAATCTTTCGTATCATGCGAATTTTGCGCATCCTTAAGTTGGCTCGTCACTCCACTGGGTTGCAATCACTGGGCTTCACGCTGCGTCGGAGTTACAATGAGCTAGGCCTGCTTATCCTCTTCTTAGCAATGGGGATCATGATCTTTTCCAGTCTAGTTTTCTTCGCGGAGAAGGATGAGGATGACACCAAGTTCAAGAGTATCCCTGCCTCCTTCTGGTGGGCCACTATTACCATGACAACTGTTGGATATGGAGACATTTACCCTAAGACGCTTCTGGGCAAGATCGTTGGTGGTCTCTGCTGCATAGCTGGAGTTTTAGTCATTGCCCTACCCATTCCTATTATCGTCAACAACTTCTCTGAATTCTACAAGGAACAGAAACGACAAGAGAAGGCCATCAAGAGACGTGAGGCTCTAGAGCGGGCTAAACGCAATGGCAGTATAGTTTCCATGAATGTTAGAGAGGCCTTTTCCCGAGGTACAGATCTTCTGGATGTTGTAGTCATGGATAAGGGTGAGAGATCTCAGGACAACCATCTCTCACCCAGTCGATGGAAATGGTCATCAAAGCGGGGAACTTCAGAGACCAGTTCTAATCGTTCCTTTAACCCAGACCAAGGTTCCCCAAGCAAGGCAAGAGCTTCTAGTCCACAGAGACTCAATGCACAGAAACTAGAAGACATGTACAACCAGATGGCAAAGACTCAGTCACAGCCCAACCTAAACACCAAAGACAGAAATTCATCCCGAGCAGGCCATAGAAGGGATGAAATTGAGCTGGGAGCCTTGCCAGGTCAAGGAGGCGACCCAATGAATGGGGGCCGTGAAGGGGTGGTAGACATGAAAAGTCTGTCGAGCATTGACAGTTATATCAGCTGTGCAACAGACTTTCAGGAGAACCCACGATTCCACTACAGTCCGGCAGGGGGTCTGTCGCTCCCAGAGAGCTCTCGGTTTTCCCACAGCCCCGGTTCTGGCCTATCTAGTCGAGTCAgtgcaaatccaagtctgcagACTACCTTAGAACACGAGACCATGCTCACTCCCCCTTTTTCTGGTGCTAAACCTCTCAACACTGATGGTTCACGGCAGCAAGGTCTGCTTGGAAACTCTCAGAAAATGCATTCAGTTAGGGTGAATCCTCGCAATTGTGCAGAGAGCAGTCCTTCAGGTGGCCCTCTGTCTGACAGCTCTATTCTTTCCGACCACTCCATCTTAAGCCCAGAAGTGTCAGTCTACACAACAGCCAGTACCAGGACTCCACCTAAGACACCTGAGAGGAAGGTACTCACTCCTACAGTCTTTACTTTTCATGACGCATCTATCAGCAAGTACATTGATGCCGACACAGATGATGAGGAGCACTTGCGCGAAAGCGGCCCATCAGATCGCCTACTGGGTGGCCTGAGCTCCAAGCCTCGGCTTGGTGGTTACCAGGGGGCCACCAACCACTTGGAAGCTGCCCAAAGGCTGCTAGGTCAGAACTGTCTATTCCCACTGGGAAGTAGCCCGAGTGTTGGGCATGAGAACCATGTGGCTTCAGAGAATTCACGGAGACCCAAAGGGGACAGGGGACATTCCAACGCTTTTGATAAGGGCCTTTGA
>TCONS_00064378
GCTGCAGCGACGCCTGAACCGAGGCTGCTTCAGACCTGCTCCAAGGAGCTGATGCCGTCCTCCCTAACGCATATCAAATAAAGCAGGGATATAGTTTTCAGCATTGCCCTCTCTTCAGGCGCCATTTTCACACAGGTTACTCGTAACGACACAGAAGGAGCTGCTCCAAGAGCCTCTCGGTGCGGGTGGCAAAAGGGTTAAACGCGCCGTCTCTCTGCCATTGGGCGGCGAGACTATGGAGATCCTGCCATCTGCAAGGAAAGCAGCTGTCGACTTCACGCAAGACACGTTAGATAGCAGTGAATGAAAACAGCGTGGATTCGCCCCAAGACttgttgatcttttttttccACGAGAAACGAGCGGAGCGGTATGTGTTTGTGTGGAGGAGACGCACGAGCTGCTGTGCGCCGGCTGTGTTTGAACTGTGACGTCCTTGCGCTTTCTTCCATTTAAACGCTTTATTTCACGCCGCTGTCAGCAATGAGTCTCCACAAATTAAGCTCAAACAGAATGAAACAGCTCGGAAAACCACTATCCACACCGCCTGTCCCACGGCCAAACTCATAGTGTAgccctacacaaacacacaagatgGAGAAACCCTCGGCAGGAATGAGTAAAGTTGGCTCTCGCTCGACAGCCTCTCTGCCCCCGGAGCCTGTGGATATAATCCGGAGTATGTCCTGCTACCGGCGTGTCAAACTGAACGTAGGTGGTCTGCCGCATGAGGTCCTGTGGAGAACCCTGGACCGACTGCCGCGCACGCGACTGGGCAAGCTGCGAGACTGCAAAACCCACGAATCCCTCATGGAAGTATGTGACGACTACAACCTGGAGGACAACGAGTACTTTTTTGACCGGCATCCCGGGGCCTTCACTTCCATACTGAACTTCTACCGCACTGGGAAGCTGCACATGATGGAGGAGATGTGCGCCCTGTCCTTCAGCCAGGAGCTGGACTACTGGGGAGTGGATGAGATCTACTTGGAGTCGTGCTGCCAGGCCAGATACCATCAAAAGAAGGAGCAGATGAACGAGGAGCTCAAGCGAGAAGCTGATACGCTGAAGGACCGAGAGGGTGAAGAATTCGATAATACGTGTTGTTCGGAGAAAAGGAAGAAATTATGGGATCTACTGGAGAAACCGGGATCGTCTGTAGCAGCCAAGATCTTGGCCATCATATCAATCCTATTCATCGTGCTCTCCACTATCGCTTTGTCTCTCAACACTCTCCCGGAACTTCAAGAAACAGACGAATTTGGTCAAACTACTGATAATACCCAGCTGGCTCACGTGGAGGCAGTGTGCATTGCTTGGTTCACCATGGAATATCTTCTTCGCTTCCTTTCCTCACCAAACAAATGGAAATTCTTTAAAGGTCCTCTTAATGTCATCGACCTGCTTGCCATCCTACCATATTATGTCACCATATTCTTGACAGAGTCCAACAAAAGTGTACTGCAATTCCAGAATGTAAGACGGGTGGTGCAAATCTTTCGTATCATGCGAATTTTGCGCATCCTTAAGTTGGCTCGTCACTCCACTGGGTTGCAATCACTGGGCTTCACGCTGCGTCGGAGTTACAATGAGCTAGGCCTGCTTATCCTCTTCTTAGCAATGGGGATCATGATCTTTTCCAGTCTAGTTTTCTTCGCGGAGAAGGATGAGGATGACACCAAGTTCAAGAGTATCCCTGCCTCCTTCTGGTGGGCCACTATTACCATGACAACTGTTGGATATGGAGACATTTACCCTAAGACGCTTCTGGGCAAGATCGTTGGTGGTCTCTGCTGCATAGCTGGAGTTTTAGTCATTGCCCTACCCATTCCTATTATCGTCAACAACTTCTCTGAATTCTACAAGGAACAGAAACGACAAGAGAAGGCCATCAAGAGACGTGAGGCTCTAGAGCGGGCTAAACGCAATGGCAGTATAGTTTCCATGAATGTTAGAGAGGCCTTTTCCCGAGGTACAGATCTTCTGGATGTTGTAGTCATGGATAAGGGTGAGAGATCTCAGGACAACCATCTCTCACCCAGTCGATGGAAATGGTCATCAAAGCGGGGAACTTCAGAGACCAGTTCTAATCGTTCCTTTAACCCAGACCAAGGTTCCCCAAGCAAGGCAAGAGCTTCTAGTCCACAGAGACTCAATGCACAGAAACTAGAAGACATGTACAACCAGATGGCAAAGACTCAGTCACAGCCCAACCTAAACACCAAAGACAGAAATTCATCCCGAGCAGGCCATAGAAGGGATGAAATTGAGCTGGGAGCCTTGCCAGGTCAAGGAGGCGACCCAATGAATGGGGGCCGTGAAGGGGTGGTAGACATGAAAAGTCTGTCGAGCATTGACAGTTATATCAGCTGTGCAACAGACTTTCAGGAGAACCCACGATTCCACTACAGTCCGGCAGGGGGTCTGTCGCTCCCAGAGAGCTCTCGGTTTTCCCACAGCCCCGGTTCTGGCCTATCTAGTCGAGTCAgtgcaaatccaagtctgcagACTACCTTAGAACACGAGACCATGCTCACTCCCCCTTTTTCTGGTGCTAAACCTCTCAACACTGATGGTTCACGGCAGCAAGGTCTGCTTGGAAACTCTCAGAAAATGCATTCAGTTAGGGTGAATCCTCGCAATTGTGCAGAGAGCAGTCCTTCAGGTGGCCCTCTGTCTGACAGCTCTATTCTTTCCGACCACTCCATCTTAAGCCCAGAAGTGTCAGTCTACACAACAGCCAGTACCAGGACTCCACCTAAGACACCTGAGAGGAAGGTACTCACTCCTACAGTCTTTACTTTTCATGACGCATCTATCAGCAAGTACATTGATGCCGACACAGATGATGAGGAGCACTTGCGCGAAAGCGGCCCATCAGATCGCCTA

Function


symbol description
kcnb1 Predicted to enable delayed rectifier potassium channel activity. Acts upstream of or within epiboly and ventricular system development. Predicted to be located in several cellular components, including lateral plasma membrane; perikaryon; and sarcolemma. Predicted to be part of voltage-gated potassium channel complex. Predicted to be integral component of membrane. Is expressed in brain; central canal; otic vesicle; and ventricular system. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 26 and epilepsy. Orthologous to human KCNB1 (potassium voltage-gated channel subfamily B member 1).

GO:

id name namespace
GO:0071805 potassium ion transmembrane transport biological_process
GO:0021591 ventricular system development biological_process
GO:0034765 regulation of ion transmembrane transport biological_process
GO:0051260 protein homooligomerization biological_process
GO:0055085 transmembrane transport biological_process
GO:0006811 ion transport biological_process
GO:0006813 potassium ion transport biological_process
GO:0090504 epiboly biological_process
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0008076 voltage-gated potassium channel complex cellular_component
GO:0005216 ion channel activity molecular_function
GO:0005244 voltage-gated ion channel activity molecular_function
GO:0005249 voltage-gated potassium channel activity molecular_function
GO:0005251 delayed rectifier potassium channel activity molecular_function
GO:0005267 potassium channel activity molecular_function

KEGG:

id description
ko04040 Ion channels

ZFIN:

id description
ZDB-GENE-090831-3 Predicted to enable delayed rectifier potassium channel activity. Acts upstream of or within epiboly and ventricular system development. Predicted to be located in several cellular components, including lateral plasma membrane; perikaryon; and sarcolemma. Predicted to be part of voltage-gated potassium channel complex. Predicted to be integral component of membrane. Is expressed in brain; central canal; otic vesicle; and ventricular system. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 26 and epilepsy. Orthologous to human KCNB1 (potassium voltage-gated channel subfamily B member 1).

Ensembl:

ensembl_id ENSDARG00000060095

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00064377 False 2505 mRNA 0.50 2 46507609 46560207
TCONS_00064378 True 2889 mRNA 0.50 3 46507819 46565466

Neighbor


gene id symbol gene type direction distance location
XLOC_033125 rdh20 coding downstream 33126 46458416 ~ 46474483 (-)
XLOC_033124 camk1a coding downstream 104134 46353910 ~ 46403475 (-)
XLOC_033123 CU041346.1 coding downstream 197598 46294361 ~ 46310011 (-)
XLOC_033121 BX005101.1 coding downstream 255669 46168017 ~ 46251940 (-)
XLOC_033122 BX005101.2 coding downstream 279377 46228117 ~ 46228232 (-)
XLOC_033127 ptgis coding upstream 2653 46568119 ~ 46589726 (-)
XLOC_033128 tarbp2 coding upstream 160074 46725540 ~ 46735380 (-)
XLOC_033129 zgc:66479 coding upstream 170785 46736251 ~ 46742455 (-)
XLOC_033130 igfn1.2 coding upstream 177780 46743246 ~ 46768040 (-)
XLOC_033131 igfn1.4 coding upstream 206188 46771654 ~ 46790042 (-)
XLOC_033118 NA non-coding downstream 578434 45923942 ~ 45929175 (-)
XLOC_033111 NA non-coding downstream 2505067 43979711 ~ 44002542 (-)
XLOC_033135 CABZ01055240.1 non-coding upstream 590836 47156302 ~ 47156416 (-)
XLOC_033138 AL929512.1 non-coding upstream 1037133 47602599 ~ 47602715 (-)
XLOC_033141 NA non-coding upstream 1413839 47979305 ~ 48061659 (-)
XLOC_033145 CU469362.1 non-coding upstream 1814779 48380245 ~ 48381223 (-)
XLOC_033148 CU137649.1 non-coding upstream 2046568 48612034 ~ 48612150 (-)

Expression



Co-expression Network