XLOC_033127 (ptgis)


Basic Information

Item Value
gene id XLOC_033127
gene name ptgis
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007117.7
NCBI id CM002890.2
chromosome length 60270059
location 46568119 ~ 46589726 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00064379
CCAGGGCAGAAGAACACAAACATAGGCTACTTGTCATGATGTGGACTGCTCTTCTGCTGGTGGGACTCTCTATTCTGGTAATAGTACTGTACGGGAGACGAACAAGACGAAGAAATGAACCGCCACTTGATAAAGGAATGATTCCTTGGCTTGGTCACGCGCTCGAGTTTGGAAAAGATGCTGCCAAATTTCTGACACGGATGAAAGAGAAGCACGGAGACATTTTTACAGTGCGTGCAGCTGGACTATATATCACCGTTCTGCTGGACTCAAACTGCTATGATGCCGTTCTGTCAGATGTGGCATCTCTTGACCAGACCAGCTATGCTCAGGTTCTCATGAAGAGAATCTTCAACATGATTCTGCCCAGTCACAACCCTGAATCTGAGAAGAAACGAGCAGAGATGCATTTTCAAGGGGCCTCTTTGACTCAACTATCCAACTCAATGCAGAACAACCTCCGCCTGCTTATGACCCCTTCAGAAATGGGTCTCAAAACATCTGAGTGGAAAAAAGATGGACTGTTCAATCTTTGCTACAGCTTGCTCTTCAAGACTGGCTATCTGACAGTGTTTGGCGCAGAGAATAACGATAGTGCAGCTCTAACCCAAATTTACGAGGAGTTTCGCCGGTTCGACAAGCTTTTGCCTAAACTTGCTCGAACTACAATCAACAAAGAGGAGAAACAAATTGCAAGTGCAGCACGAGAAAAACTGTGGAAATGGCTGACTCCATCAGGTTTAGATAGAAAGCCAAGAGAGCAGTCATGGTTGGGAAGCTACGTAAAGCAACTTCAAGATGAAGGCATTGATGCTGAGATGCAGAGGAGAGCGATGCTGCTGCAACTCTGGGTCACACAGGGAAACGCAGGCCCTGCTGCATTCTGGGTAATGGGCTACTTACTCACCCACCCTGAAGCTCTGAGGGCTGTAAGAGAGGAAATCCAAGGTGGAAAACACCTTCGTCTGgaagaaagacagaaaaacacTCCAGTCTTTGATAGTGTTCTTTGGGAGACGCTGCGTTTAACTGCAGCTGCCCTCATCACTAGGGATGTGACGCAGGACAAAAAGATTCGTTTAAGCAATGGGCAAGAATACCATCTCCGACGGGGCGATCGGCTGTGCGTTTTCCCCTTCATCAGCCCGCAAATGGACCCACAGATTCACCAACAGCCAGAGATGTTCCAGTTTGACCGCTTTCTTAATGCAGACAGGACAGAGAAGAAGGACTTTTTTAAGAATGGGGCAAGGGTGAAATATCCCTCTGTGCCCTGGGGAACCGAAGATAACCTCTGTCCAGGACGCCATTTTGCAGTTCATGCAATTAAAGAGCTTGTGTTCACCATCCTGACTCGATTTGATGTTGAACTGTGTGACAAGAATGCAACGGTGCCATTGGTGGATCCCAGTCGATATGGCTTTGGCATTCTCCAACCAGCGGGTGATCTAGAGATACGCTACAGAATAAGATTTTGACAGCGGTAATATGCCAAAcctgattaataaaaatactaataattattattatttacaactgtacaGATAACAACAAGCCTTTTTTGAGTGCATGCTGCGTGCTATTTGcagaaataaatattgtatttaataaataaatattgttttttaataaactcTAGTTTAGTCAA
>TCONS_00064380
ATCTAGTAAAATATCTGGGATTAGCCATTCAAGTGCTGCCACTGGCACAAAGACAAAATGGGGGAAGGGGTCACATTTTATAGTCACTGCTGCTGCTATCTGTGAGAAACAGGCGCACACAACATAAACATATCATAGGCCAAAATGCTGACATTGTACATTGGCACCCAGAACCGAAGATCTGATCCAAGCTTCCATGTTAAATCATTCCATGTGGATTACAGTGAAATGATCAGCGAACATACCATTGCTTTACAAATGTTTCATCTCTAGACAATCTGATGCTGTTTTGACTGTTGCGTACAACAAATATCATTACACCAATCAAAAACTCAGtcattaattatgtttatctCCTTGTAATCCAACAGATGTTCCAGTTTGACCGCTTTCTTAATGCAGACAGGACAGAGAAGAAGGACTTTTTTAAGAATGGGGCAAGGGTGAAATATCCCTCTGTGCCCTGGGGAACCGAAGATAACCTCTGTCCAGGACGCCATTTTGCAGTTCATGCAATTAAAGAGCTTGTGTTCACCATCCTGACTCGATTTGATGTTGAACTGTGTGACAAGAATGCAACGGTGCCATTGGTGGATCCCAGTCGATATGGCTTTGGCATTCTCCAACCAGCGGGTGATCTAGAGATACGCTACAGAATAAGATTTTGACAGCGGTAATATGCCAAAcctgattaataaaaatactaataattattattatttacaactgtacaGATAACAACAAGCCTTTTTTGAGTGCATGCTGCGTGCTATTTGcagaaataaatattgtatttaataaataaatattgttttttaataaa

Function

symbol description
ptgis Enables heme binding activity and prostaglandin-I synthase activity. Involved in prostaglandin biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in essential hypertension and hypertension. Orthologous to human PTGIS (prostaglandin I2 synthase).

GO:

id name namespace
GO:0006629 lipid metabolic process biological_process
GO:0006631 fatty acid metabolic process biological_process
GO:0006633 fatty acid biosynthetic process biological_process
GO:0006693 prostaglandin metabolic process biological_process
GO:0001516 prostaglandin biosynthetic process biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0005783 endoplasmic reticulum cellular_component
GO:0005789 endoplasmic reticulum membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0008116 prostaglandin-I synthase activity molecular_function
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen molecular_function
GO:0004497 monooxygenase activity molecular_function
GO:0005506 iron ion binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0016829 lyase activity molecular_function
GO:0016853 isomerase activity molecular_function
GO:0020037 heme binding molecular_function

KEGG:

id description
ko00590 Arachidonic acid metabolism
ko00199 Cytochrome P450

ZFIN:

id description
ZDB-GENE-070116-1 Enables heme binding activity and prostaglandin-I synthase activity. Involved in prostaglandin biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in essential hypertension and hypertension. Orthologous to human PTGIS (prostaglandin I2 synthase).

Ensembl:

ensembl_id ENSDARG00000060094

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00064379 False 1648 mRNA 0.45 10 46568119 46589726
TCONS_00064380 True 823 lncRNA 0.39 2 46568134 46571429

Neighbor

gene id symbol gene type direction distance location
XLOC_033126 kcnb1 coding downstream 2653 46507609 ~ 46565466 (-)
XLOC_033125 rdh20 coding downstream 93636 46458416 ~ 46474483 (-)
XLOC_033124 camk1a coding downstream 164644 46353910 ~ 46403475 (-)
XLOC_033123 CU041346.1 coding downstream 258108 46294361 ~ 46310011 (-)
XLOC_033121 BX005101.1 coding downstream 316179 46168017 ~ 46251940 (-)
XLOC_033128 tarbp2 coding upstream 135814 46725540 ~ 46735380 (-)
XLOC_033129 zgc:66479 coding upstream 146525 46736251 ~ 46742455 (-)
XLOC_033130 igfn1.2 coding upstream 153520 46743246 ~ 46768040 (-)
XLOC_033131 igfn1.4 coding upstream 181928 46771654 ~ 46790042 (-)
XLOC_033132 igfn1.3 coding upstream 253866 46843592 ~ 46875310 (-)
XLOC_033122 BX005101.2 non-coding downstream 339887 46228117 ~ 46228232 (-)
XLOC_033118 NA non-coding downstream 638944 45923942 ~ 45929175 (-)
XLOC_033111 NA non-coding downstream 2565577 43979711 ~ 44002542 (-)
XLOC_033135 CABZ01055240.1 non-coding upstream 566576 47156302 ~ 47156416 (-)
XLOC_033138 AL929512.1 non-coding upstream 1012873 47602599 ~ 47602715 (-)
XLOC_033141 NA non-coding upstream 1389579 47979305 ~ 48061659 (-)
XLOC_033145 CU469362.1 non-coding upstream 1790519 48380245 ~ 48381223 (-)
XLOC_033148 CU137649.1 non-coding upstream 2022308 48612034 ~ 48612150 (-)

Expression


Co-expression Network