XLOC_033140 (RAP1GAP)


Basic Information

Item Value
gene id XLOC_033140
gene name RAP1GAP
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007117.7
NCBI id CM002890.2
chromosome length 60270059
location 47869397 ~ 47953829 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00064399
CACTGTCAAAAGCAGACGCAGACAGAGCAGAAGGAGGTTAACAGGGGAAAAAACCAAGCATGTCTCACAGGAAGAGGAGCTTCACTTTTGGAGCATATGGGGGAGTGGACAAAACTTTCTCCAGGTCAAGGCATGTTTGgAAGCAAGATGGCAGAATCCCGCGAATATCTGACCCGCTAGAACGTCCTGGTCGGGTCAAGTCCTTACCACCATTACCTGCTCAGACTCTTCTAAAGAGCAGTAGAATGGATGAGCAGCGGTGCTCTCTTCCACCTCCTCTCAAAACAGAGGAAGACTACATTCCATATCCCAGCGTCCATGAGGTATTGGGGCGCACAGGCACTTTACCCCTGATCCTGCTGCCTCAGTTTGGGGGTTACTGGATTGAAGGAACCAATCATGATTTAGGCTCCTCCTCCACACCTGAGGAACCGCCCCCTTGTCCTGCATCACAGGTTAAACTGGAGACCAACAGCATAGCCAAGATCTACAGGAAAGACTTTCTGGGGAAGGAGCACTTTAATTATTACTCAGTGGACAGTGCTCTGGGACACCTGATCTTTTCCATGAAGTATGATGTGATTGGAGACCAGGAGCACCTTCGACTGCTGCTCAGGTCAAGGTTTAAAACTTACCACGATGTGATACCAATTTCTTGTCTGACTGAGTTCCCTAACGTCATCCAGATGGCAAAgcttgTCTGTGAAGAGGTGAATGTGGACAGATTTTATCCTGTCTTATATCCAAAGGCTTCGAGACTCATCGTGACCTTCGATGAGCACGTCATCAGCAACAACTTCAAGTTTGGAGTTATTTACCAGAAGTTTGCCCAGACATCAGAAGAGGAGCTGTTCGGAAATAACGAGGAAAGTCCAGCTTTTGTTGAGTTTCTGGAGTTCCTGGGAGAGAAGATTGATCTTCATGATTTTAAAGGTTTTCGTGGTGGCCTGGATGTGACACATGGCCAGACAGGAACCGAGTCGGTGTATGTTAACTTTCACAATAAAGAGATCATGTTCCACGTGTCCACCAAACTGCCCTACACTGAAGGAGATTCACAGCAGCTCCAGAGGAAGAGGCATATAGGAAATGACATTGTGGCCATTGTGTTTCAAGAAGAAAACACACCGTTTGTACCTGATATGATTGCATCCAACTTTCTTCATGCTTATGTGGTGGTGCAGGTGGAGAACGCCTGCACTGATAACGTCCTCTATAAGGTGTCTGTAACAGCAAGAGACGATGTGCCTTTTTTTGGTCCAGCTCTGCCAGATCCAGCTGTCTTTAAAAAGAGTTCAGAATTTCATGAATTCCTCTTGACCAAACTGATCAATGCTGAATATTCCTGTTATAAAGCAGAGAAGTTTGCCAAGCTTGAGGAAAGAACGCGTTCGGCTCTGCTGGAGACTTTATATGAGGAGCTGCATATGAACAGCCAGTCCATGATGGGTTTAGGTGGAGACGACGACAAGCTGGAgaatggaggaggaggaggaggaggaggattcTTCGAGTCTTTCAAGCGAGTAATCCGCAACAGAAGTCAGTCTATGGATGCTATGGGCCTCAGTAACAAGAAACCACACACTGTCTCCACAAGCCACAGTGGAAGCTTTACCCACAATCCTCCAGAAACCCCCAAAACACCTGGCATTTCCCTGATTATTCCTGGAAAAAGTCCAACACGTAAGAAATCCGGTCCGTTCAGTTCCAGGAGGAGCAGCGCCATTGGGATTGAGAACATACAAGAGGTTCAGGAGAGAAGTAGTCGAGAGGTGTCCCCGAGTCCACAGAGGTCATCTGATGGTGGACACATCGCTCAGGAATTTCGGCTAGACAACTCGTCCAATCAGAGCTCACCTGAGATGGCAACCACTAAGATCGGttcGGCCCTGTGCTGTCGAGCTCCATCTATCCCCGAGTCTCAGGATTTGTCTCGCTCCTCGTCCAACGCCAGCAGCTTTACCAGTGTAGTGGAGGATCATGAAGCGACAGAGGACTACGACACAGGACTGGAGAGTCTGTCTTCAGCCGGTACACCTCACAAACGAGATTCATTTCCATACAGCTCTGTGTGGTTGGAGGACGCTTCTGCTAGCTCCAGTCAGAGCAGTCCACATGCAGGTCCCTTTCGACAGCAGTCTGAACCTCTACGTCCAAAAACAGAGAGACAACACTCGAACTGCTAGCTGTCCTGTAGGCCGTAAATGACTTCATGGATGTCCATCAGCAGCATTTTCATAAGCAGCCTCCGCAGCGGACACTGTTCGTGCTCACAGCAGAAACGGATGTGAAGGAGATGGAGGCGCTAGCTTCAGTCCTGCGGAGAACAGAATATGAGCGGGACAACAACCACTTAATCTTCTGTCATCAAGAGAAACGGCAAACCTGCCTGGCCAGAGCTAAGGAACAAGAGCTGGCAGCTGGGAAACAACCACGCATGATCTTAAGGCCTATTCTGAGCCATCTTTCTTTCGTTCTCATAATGGTGGCCCTCGTTGTGTGGGTCTTtctttgtcatatttatttatttattgaggcTCACTGGTGGAGCAGGGCTTTCAGAATGACACCCGAGGTTCAACCTTAAACAATCATGCTTAAAATACACCGTAATGCACATCTTTGTGTGTGATTCTGATTCGTTTTGTGTCAGTAATGGTGTTGAATTTCGGTAAATGTTAAATGTCGTTCTTCGGTGTAGTTCTGATGTTACAAATCCAGGCCTTTTTTAGATCACGTCTCGTAAACTAAACACAGGCATTATTATCATTTATGACAAAACGTATCGATCCGGTGTGAGATGCTGTAtacttttgaaatattatttattacctTTAATGCCGATCGACATATTTTGTATGGCCACGGCTGCTCTTGGTTAAactgacatgtgtgtgtgtgtgtacactaatGTAGTCGCTTCATGTTTGTAGTGTCATGTTTTAAAACTAGATATTAAGGGTCAGAGTCTCTCAAGTCTGTTTTGCTTTTGTGGTGAGCGAGCAATATGAATGTAAACCTGGACTAAAAACACTAGGTCAGAATATACTCCACAGAACAAATGTTGGACGTTTTATTTCCTTTTCAAACACAAATGCAcgttttattaaactttttttttttttttatgaaatgtttCTATTTCAGACTGTTTAATCGATGTGTTCGTTTTTTtacttaaagaaatagttcatccaaaactgaaatgtGCTTAGTTGATTGGCCAGCAGCATTTTGAACAGCAAAACAACATATGTGGAACCATATGCAGAAAGGTCTGCGGTAGGGCTGCACGATCctggctaaaatgaaaatcacaatttttttttttgcttaaaat
>TCONS_00064400
ATGGATGAGCAGCGGTGCTCTCTTCCACCTCCTCTCAAAACAGAGGAAGACTACATTCCATATCCCAGCGTCCATGAGGTATTGGGGCGCACAGGCACTTTACCCCTGATCCTGCTGCCTCAGTTTGGGGGTTACTGGATTGAAGGAACCAATCATGATTTAGGCTCCTCCTCCACACCTGAGGAACCGCCCCCTTGTCCTGCATCACAGGTTAAACTGGAGACCAACAGCATAGCCAAGATCTACAGGAAAGACTTTCTGGGGAAGGAGCACTTTAATTATTACTCAGTGGACAGTGCTCTGGGACACCTGATCTTTTCCATGAAGTATGATGTGATTGGAGACCAGGAGCACCTTCGACTGCTGCTCAGGTACTTCAAGTTTAAAACTTACCACGATGTGATACCAATTTCTTGTCTGACTGAGTTCCCTAACGTCATCCAGATGGCAAAgcttgTCTGTGAAGAGGTGAATGTGGACAGATTTTATCCTGTCTTATATCCAAAGGCTTCGAGACTCATCGTGACCTTCGATGAGCACGTCATCAGCAACAACTTCAAGTTTGGAGTTATTTACCAGAAGTTTGCCCAGACATCAGAAGAGGAGCTGTTCGGAAATAACGAGGAAAGTCCAGCTTTTGTTGAGTTTCTGGAGTTCCTGGGAGAGAAGATTGATCTTCATGATTTTAAAGGTTTTCGTGGTGGCCTGGATGTGACACATGGCCAGACAGGAACCGAGTCGGTGTATGTTAACTTTCACAATAAAGAGATCATGTTCCACGTGTCCACCAAACTGCCCTACACTGAAGGAGATTCACAGCAGCTCCAGAGGAAGAGGCATATAGGAAATGACATTGTGGCCATTGTGTTTCAAGAAGAAAACACACCGTTTGTACCTGATATGATTGCATCCAACTTTCTTCATGCTTATGTGGTGGTGCAGGTGGAGAACGCCTGCACTGATAACGTCCTCTATAAGGTGTCTGTAACAGCAAGAGACGATGTGCCTTTTTTTGGTCCAGCTCTGCCAGATCCAGCTGTCTTTAAAAAGAGTTCAGAATTTCATGAATTCCTCTTGACCAAACTGATCAATGCTGAATATTCCTGTTATAAAGCAGAGAAGTTTGCCAAGCTTGAGGAAAGAACGCGTTCGGCTCTGCTGGAGACTTTATATGAGGAGCTGCATATGAACAGCCAGTCCATGATGGGTTTAGGTGGAGACGACGACAAGCTGGAgaatggaggaggaggaggaggaggaggattcTTCGAGTCTTTCAAGCGAGTAATCCGCAACAGAAGTCAGTCTATGGATGCTATGGGCCTCAGTAACAAGAAACCACACACTGTCTCCACAAGCCACAGTGGAAGCTTTACCCACAATCCTCCAGAAACCCCCAAAACACCTGGCATTGTGAGTATGAACACTCTTCTCAATTCCCTGATTATTCCTGGAAAAAGTCCAACACGTAAGAAATCCGGTCCGTTCAGTTCCAGGAGGAGCAGCGCCATTGGGATTGAGAACATACAAGAGGTTCAGGAGAGAAGTAGTCGAGAGGTGTCCCCGAGTCCACAGAGGTCATCTGATGGTGGACACATCGCTCAGGAATTTCGGCTAGACAACTCGTCCAATCAGAGCTCACCTGAGATGGCAACCACTAAGATCGGttcGGCCCTGTGCTGTCGAGCTCCATCTATCCCCGAGTCTCAGGATTTGTCTCGCTCCTCGTCCAACGCCAGCAGCTTTACCAGTGTAGTGGAGGATCATGAAGCGACAGAGGACTACGACACAGGACTGGAGAGTCTGTCTTCAGCCGGTACACCTCACAAACGAGATTCATTTCCATACAGCTCTGTGTGGTTGGAGGACGCTTCTGCTAGCTCCAGTCAGAGCAGTCCACATGGTGAGATCCAACAGACATTCATCTCTCAAGCAAACATTTGTGATTACACAATGATAAGATGTATGCTGGAGTTTGTGTGCAGAAACAGCTACTGGATTTAA

Function

symbol description
rap1gap Enables GTPase activator activity; protein homodimerization activity; and small GTPase binding activity. Involved in negative regulation of microvillus assembly and positive regulation of GTPase activity. Located in cytosol and membrane. Biomarker of bipolar disorder; endocrine gland cancer (multiple); focal segmental glomerulosclerosis; melanoma; and myelodysplastic syndrome.

GO:

id name namespace
GO:0051056 regulation of small GTPase mediated signal transduction biological_process
GO:0030695 GTPase regulator activity molecular_function
GO:0005096 GTPase activator activity molecular_function

KEGG:

id description
ko04015 Rap1 signaling pathway

ZFIN:

id description
ZDB-GENE-080402-9 Predicted to enable GTPase activator activity. Predicted to be involved in activation of GTPase activity. Predicted to act upstream of or within regulation of small GTPase mediated signal transduction. Predicted to be active in cytoplasm. Orthologous to human RAP1GAP (RAP1 GTPase activating protein).

Ensembl:

ensembl_id ENSDARG00000053272

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00064399 False 3343 mRNA 0.45 24 47869397 47953829
TCONS_00064400 True 2004 mRNA 0.47 18 47872403 47899405

Neighbor

gene id symbol gene type direction distance location
XLOC_033139 lrig2 coding downstream 28932 47809755 ~ 47840465 (-)
XLOC_033137 magi3b coding downstream 72408 47529881 ~ 47796989 (-)
XLOC_033138 AL929512.1 coding downstream 266682 47602599 ~ 47602715 (-)
XLOC_033136 im:7151449 coding downstream 363046 47484084 ~ 47506351 (-)
XLOC_033134 grm4 coding downstream 622449 46981486 ~ 47246948 (-)
XLOC_033141 NA coding upstream 25476 47979305 ~ 48061659 (-)
XLOC_033142 slc2a1b coding upstream 114866 48068695 ~ 48094342 (-)
XLOC_033143 st7l coding upstream 336296 48290125 ~ 48317562 (-)
XLOC_033144 capza1a coding upstream 368421 48322250 ~ 48347724 (-)
XLOC_033145 CU469362.1 coding upstream 426416 48380245 ~ 48381223 (-)
XLOC_033135 CABZ01055240.1 non-coding downstream 712981 47156302 ~ 47156416 (-)
XLOC_033123 CU041346.1 non-coding downstream 1559386 46294361 ~ 46310011 (-)
XLOC_033121 BX005101.1 non-coding downstream 1617457 46168017 ~ 46251940 (-)
XLOC_033148 CU137649.1 non-coding upstream 658205 48612034 ~ 48612150 (-)
XLOC_033149 NA non-coding upstream 961039 48914868 ~ 48949515 (-)
XLOC_033152 NA non-coding upstream 1147050 49100879 ~ 49104192 (-)

Expression


Co-expression Network