XLOC_033287 (pmepa1)


Basic Information

Item Value
gene id XLOC_033287
gene name pmepa1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007117.7
NCBI id CM002890.2
chromosome length 60270059
location 60076456 ~ 60104628 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00064592
GGACTTGAATGAGGTGCGCGCAGACGCTGGAAAGTAGTACAAACCGTCTGGGAATAACGGGAATACTGGAGCACAGCGGCCAGACAGCGGGCCGGGGGCGGGGGGACGGCGGTTAGAGGACGGTAGACACAGAATAGGAAAAGCCTGCGTCAATGTTTTTATTCGACAACGCGCGCTGAGGCGACCGACTAACCAACCGACAAACCGTCCGTTTTTCACATCGATTTCCTCAATGTTCAGCTTCATGGGTCTGACGAACGGAACCACCGACACCCTCGCCAATGTCTCCTGTACATGTAACTGCCAGAGATCCACTTCATTCCAGAGTATGGCGATCTcccaGCTGGAGTTTGTTCAGATTCTGGTGATcgtggtggtgatgatgatgatggtgctgGTGATCACGTGTTTGCTGAACCACTACAGACTCTCAGCGCGATCTCTGATGTCCAGACACACACACGAGCGCAGACGACACCTGCCCCTGCCCTcgGAGGGCAGTCTGTGGTCTTCTGATGGGCCAGGCTCTTCTAGTGCCATGAGTGAGGTTTACACTCCTCGAGCGCCGGATAGAGTGCCGTCGTTCCTGCAGCGTGAGCGCGTGTCCCGCTTCCAGCCTACCTTCCCATTCCTCCCTCCAGTGATCGAACTGCCTCCGACCATCGCTCTGTCTGACGGCGAGGAACCTCCGCCGTATCAGGGGCCATGCACGCTTCAGCTGCGGGACCGTGAGCAGCAGCTGGAGCTCAACCGGGAGTCTGTGCGCCCGCCGCCCAACCGCACAGTGTACGACAGCGCGCTCACACACACG
>TCONS_00064593
cccaGCTGGAGTTTGTTCAGATTCTGGTGATcgtggtggtgatgatgatgatggtgctgGTGATCACGTGTTTGCTGAACCACTACAGACTCTCAGCGCGATCTCTGATGTCCAGACACACACACGAGCGCAGACGACACCTGCCCCTGCCCTcgGAGGGCAGTCTGTGGTCTTCTGATGGGCCAGGCTCTTCTAGTGCCATGAGTGAGGTTTACACTCCTCGAGCGCCGGATAGAGTGCCGTCGTTCCTGCAGCGTGAGCGCGTGTCCCGCTTCCAGCCTACCTTCCCATTCCTCCCTCCAGTGATCGAACTGCCTCCGACCATCGCTCTGTCTGACGGCGAGGAACCTCCGCCGTATCAGGGGCCATGCACGCTTCAGCTGCGGGACCGTGAGCAGCAGCTGGAGCTCAACCGGGAGTCTGTGCGCCCGCCGCCCAACCGCACAGTGTACGACAGCGCGCTCACACACAC
>TCONS_00064594
GGACTTGAATGAGGTGCGCGCAGACGCTGGAAAGTAGTACAAACCGTCTGGGAATAACGGGAATACTGGAGCACAGCGGCCAGACAGCGGGCCGGGGGCGGGGGGACGGCGGTTAGAGGACGGTAGACACAGAATAGGAAAAGCCTGCGTCAATGTTTTTATTCGACAACGCGCGCTGAGGCGACCGACTAACCAACCGACAAACCGTCCGTTTTTCACATCGATTTCCTCAATGTTCAGCTTCATGGGTCTGACGAACGGAACCACCGACACCCTCGCCAATGTCTCCTGTACATGTAACTGCCAGAGATCCACTTCATTCCAGAGTATGGCGATCT

Function

symbol description
pmepa1 Predicted to enable R-SMAD binding activity. Predicted to be involved in negative regulation of SMAD protein complex assembly; negative regulation of pathway-restricted SMAD protein phosphorylation; and negative regulation of transforming growth factor beta receptor signaling pathway. Predicted to act upstream of or within negative regulation of signal transduction. Predicted to be located in endosome and membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi membrane and early endosome membrane. Is expressed in brain; liver; ventricular zone; and yolk syncytial layer. Orthologous to human PMEPA1 (prostate transmembrane protein, androgen induced 1).

GO:

id name namespace
GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation biological_process
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway biological_process
GO:0010991 negative regulation of SMAD protein complex assembly biological_process
GO:0000139 Golgi membrane cellular_component
GO:0031901 early endosome membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0070412 R-SMAD binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040718-320 Predicted to enable R-SMAD binding activity. Predicted to be involved in negative regulation of SMAD protein complex assembly; negative regulation of pathway-restricted SMAD protein phosphorylation; and negative regulation of transforming growth factor beta receptor signaling pathway. Predicted to act upstream of or within negative regulation of signal transduction. Predicted to be located in endosome and membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi membrane and early endosome membrane. Is expressed in brain; liver; ventricular zone; and yolk syncytial layer. Orthologous to human PMEPA1 (prostate transmembrane protein, androgen induced 1).

Ensembl:

ensembl_id ENSDARG00000039325

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00064592 False 811 mRNA 0.58 4 60076456 60104628
TCONS_00064593 False 472 mRNA 0.61 3 60076457 60079551
TCONS_00064594 True 338 mRNA 0.54 1 60104291 60104628

Neighbor

gene id symbol gene type direction distance location
XLOC_033286 ccndbp1 coding downstream 27184 60043053 ~ 60049272 (-)
XLOC_033285 slain1b coding downstream 44763 60024117 ~ 60031693 (-)
XLOC_033284 wbp4 coding downstream 56071 60018233 ~ 60020385 (-)
XLOC_033283 NA coding downstream 101709 59973702 ~ 59974747 (-)
XLOC_033282 fbxl3b coding downstream 134121 59935950 ~ 59942335 (-)
XLOC_033288 slc32a1 coding upstream 37991 60142619 ~ 60147517 (-)
XLOC_033289 NA coding upstream 163179 60267807 ~ 60269211 (-)
XLOC_033281 NA non-coding downstream 222773 59835630 ~ 59853683 (-)
XLOC_033280 CABZ01117510.1 non-coding downstream 391195 59685145 ~ 59685261 (-)
XLOC_033277 NA non-coding downstream 654986 59395847 ~ 59421470 (-)
XLOC_033273 NA non-coding downstream 904917 59168060 ~ 59171539 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000340_18508935_18509478 NA coding CI01000340 null 18508669 ~ 18509729 (+)