XLOC_003331 (mknk1)


Basic Information

Item Value
gene id XLOC_003331
gene name mknk1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007122.7
NCBI id CM002895.2
chromosome length 45484837
location 13176568 ~ 13189751 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00006521
CGGTTGGCGCGTTTGGGGGTGGTGCTGTTGTGTTTCTGTGTTGTCCCCCCTccacctcttcctcctcctcactGCTGCTGTTCAGCGGAGGATGGCGGAGGCAGTCCCTGTCCAGCGAGACTCATTCGGCTGCAGTTTACAGctcGCTCCACTCCTTCAGGCGCTCCACTGCTCCTGCCAGATATCCAGTAGCATTCTGGGATCGGGTAAGGTGGAGAGCCGTGGTTCGCTCTCTCGTGTCCCCAGTACCGTCTCGCAAACCTCTACAGGAATGGAGAGCAgtcaaccaatcagcatcacagACCCAAGTTCACGCCGAAAGAAGAAACGCAGAAGAGCCGGAGACAGTTTCACAGGCAAATTTTGTGATCTATACAGGCTGACGGATGAGCTGCTGGGTCAGGGAGCTTATGCCAAAGTCCAGGGCTGTGTGAGTTTACAAAATGGCACGGAGTATGCGGTAAAGATAATCGAGAAGAATGCTGGTCACAGTCGCAGCCGAGTTTTTAGAGAGGTGGAGACGCTTTACCAGTGTCAAGGAAACAAGAACATTCTGGAGCTGATTCAGTTTTTTGAAGATGACAGCTGCTTTTATCTGGTGTTTGAGAAGTTACGTGGAGGTTCCATTTTGACACACATCCAGAGTCGAAAATACTTCGACGAGAGAGAAGCGAGTCGTGTGGTCAGGGATATAGCAAATGCACTAGACTTTCTGCACAACAAAGGAATCGCCCACCGTGATCTTAAGCCTGAAAATATCCTCTGTGAATATACTGATAAGgTTTCCCCTGTGAAGATCTGTGATTTTGATCTTGGCAGTGGAGTAAAGCTGAACAGTGCCTGTACCCCAATTACCACCCCTGAGCTCACCACACCGTGTGGCTCAGCAGAGTACATGGCTCCTGAGGTGGTGGAGGTCTTCACGGACGAAGCTTCATTCTATGATAAGCGATGTGACCTCTGGAGCCTCGGGGTCATTCTCTACATCCTGCTTAGCGGGAGTCCGCCATTTACTGGCCATTGTGGCACCAACTGTGGCTGGGAACGAGGAGAAACATGTCGTTCCTGCCAGAATAATCTGTTTGAGAGGATTCAGGAGGGAAAGTATGAGTTCAGCGATGGAGTCTGGACACAGATATCAGCTGATGCCAAAGATCTGATCTCGCGGCTACTGGTGCGAGATGCCACTTTACGGCTAAGTGCCGCTCAGGTCCTGCAGCATCCCTGGGTGCAGGGGaATGCACCTGAAAGAGTTCTTCCAACTCCTCGTGTTCTACAaagAAACTGCAGCACTAAAGATCTGACGCAGTTTGCAGCTGAAGCCATCGCGTTTAACCGGCAGCTGTCGCAACAGGAAGAAGAGCAGGAAGACTTTGGCGCTGTCGTCTGCTCCATGAGGCTTTCTCCGCCTTCTAACTCTAGACTTGCCCGTCGTCGAGCACAGTCTCAAGCACTACGCAACAATACCTGAAGTCAACCCGCTGCACAGGTGCATTATAACCGTTCAGACACTTCAGAAACACACAAATGCGCATGCACCAGGTACTACCAGACTAACCTTATGTGTACTAAACCATGCACACGTCTTTAATTCATTTCGCAGGTCTGCTTGGTCGTCTTTCTGTTCACCTATTGTGGGTTTGGTATCAGAATGTTTATAATTATCGTCATATATTTATGGCTGGTGGTGATTGTTAGTCAGATATAAAAAAGTGCTCGGCTATGTGGGAGggaatagaccattttattttaatgtaacgATGACATTCGCATCGCTTTTAAATGTAAGTTAGCGTTTCTATtcttaaaacaagttttattatttttaaaaaccactTTAGTTACTGTGAAGCACTGGACCTCTTGCTCTgtcactttttttacttttatttttttacaatatttaagcAGTTGTaagtattaaataattttttgctttattttcgcTATGTACTGTAAAGCCATGCTGCCTGACAGTAACATACCATAGAATTGCGTATTATTATGAGAGGTACGATGAGGTATTATAGATATTTGACTTGTTACTTTTTAGCTTAAACTGTATTTATTGCATAGTATATTTTTGTCATTTCAGAtgattatatatttcttttaatgtattttttttgcattattttcttGTCAATGTGAAGTATTTTTTTATGCATGAGGGCAAAGAACATATTCGGTAATGAGATAgattaagttttaattttttgaTTTGCATTCAGTGGAAATTGTGCCATTTTCAGGCTTGGGGGCAGAGCTCCTGATGTGCAAAATAACTAAATTACCTCTCAAAATTGCCTTTTGTATTATCAAATCGAGTTATTTTTCCTGTTATTTGTTGCAGATTGAGCTGAGATGAAATGGTAAGAATTTAGTGATTGTccatgtattatttatttctgtacCTTCATGAGAATTTGTTAGTATACATTTCTTGTACCAGGGATGACACTAGAGGGCGCTACCTCATATTAATGCCCATGTTCTCAGCACTCAGCCAGTATGATACTGATGGAGTATCTCAGTCTACGTTCAGGAATGGTGTAAATTGAATGGCCATTTAACCCCTAATAAACTCTGGGACAGATTGTGGGGCAGGGGTGTTCATTTGGTTTTCCAATTTTGAGAAATAAAGCAATTTGCACTGAACCAAGAA
>TCONS_00006522
CGGCTGCAGTTTACAGctcGCTCCACTCCTTCAGGCGCTCCACTGCTCCTGCCAGATATCCAGTAGCATTCTGGGATCGGGTAAGGTGGAGAGCCGTGGTTCGCTCTCTCGTGTCCCCAGTACCGTCTCGCAAACCTCTACAGgaTTAGGAATGGAGAGCAgtcaaccaatcagcatcacagACCCAAGTTCACGCCGAAAGAAGAAACGCAGAAGAGCCGGAGACAGTTTCACAGGCAAATTTTGTGATCTATACAGGCTGACGGATGAGCTGCTGGGTCAGGGAGCTTATGCCAAAGTCCAGGGCTGTGTGAGTTTACAAAATGGCACGGAGTATGCGGTAAAGATAATCGAGAAGAATGCTGGTCACAGTCGCAGCCGAGTTTTTAGAGAGGTGGAGACGCTTTACCAGTGTCAAGGAAACAAGAACATTCTGGAGCTGATTCAGTTTTTTGAAGATGACAGCTGCTTTTATCTGGTGTTTGAGAAGTTACGTGGAGGTTCCATTTTGACACACATCCAGA
>TCONS_00006523
CAAGGGCAACTAAACGCAAAATAATGATTAGTAGTTTATATTATACAAACTAAATGTAACCATTTGGTGTTTGCTTtaaatataatcatatttatttgttttccagaATGCACCTGAAAGAGTTCTTCCAACTCCTCGTGTTCTACAaagAAACTGCAGCACTAAAGATCTGACGCAGTTTGCAGCTGAAGCCATCGCGTTTAACCGGCAGCTGTCGCAACAGGAAGAAGAGCAGGAAGACTTTGGCGCTGTCGTCTGCTCCATGAGGCTTTCTCCGCCTTCTAACTCTAGACTTGCCCGTCGTCGAGCACAGTCTCAAGCACTACGCAACAATACCTGAAGTCAACCCGCTGCACAGGTGCATTATAACCGTTCAGACACTTCAGAAACACACAAATGCGCATGCACCAGGTACTACCAGACTAACCTTATGTGTACTAAACCATGCACACGTCTTTAATTCATTTCGCAGGTCTGCTTGGTCGTCTTTCTGTTCACCTATTGTGGGTTTGGTATCAGAATGTTTATAATTATCGTCATATATTTATGGCTGGTGGTGATTGTTAGTCAGATATAAAAAAGTGCTCGGCTATGTGGGAGggaatagaccattttattttaatgtaacgATGACATTCGCATCGCTTTTAAATGTAAGTTAGCGTTTCTATtcttaaaacaagttttattatttttaaaaaccactTTAGTTACTGTGAAGCACTGGACCTCTTGCTCTgtcactttttttacttttatttttttacaatatttaagcAGTTGTaagta

Function

symbol description
mknk1 Predicted to enable calcium-dependent protein serine/threonine kinase activity; calmodulin binding activity; and calmodulin-dependent protein kinase activity. Predicted to be involved in intracellular signal transduction; peptidyl-serine phosphorylation; and protein autophosphorylation. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in cytoplasm and nucleus. Orthologous to human MKNK1 (MAPK interacting serine/threonine kinase 1).

GO:

id name namespace
GO:0018105 peptidyl-serine phosphorylation biological_process
GO:0035556 intracellular signal transduction biological_process
GO:0006468 protein phosphorylation biological_process
GO:0016310 phosphorylation biological_process
GO:0046777 protein autophosphorylation biological_process
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0016740 transferase activity molecular_function
GO:0005516 calmodulin binding molecular_function
GO:0005524 ATP binding molecular_function
GO:0009931 calcium-dependent protein serine/threonine kinase activity molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function
GO:0004683 calmodulin-dependent protein kinase activity molecular_function
GO:0016301 kinase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-080220-11 Predicted to enable calcium-dependent protein serine/threonine kinase activity; calmodulin binding activity; and calmodulin-dependent protein kinase activity. Predicted to be involved in intracellular signal transduction; peptidyl-serine phosphorylation; and protein autophosphorylation. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in cytoplasm and nucleus. Orthologous to human MKNK1 (MAPK interacting serine/threonine kinase 1).

Ensembl:

ensembl_id ENSDARG00000018411

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00006521 False 2665 mRNA 0.44 14 13176568 13189751
TCONS_00006522 False 524 mRNA 0.50 8 13176694 13182833
TCONS_00006523 True 789 lncRNA 0.39 2 13188135 13189006

Neighbor

gene id symbol gene type direction distance location
XLOC_003330 mob3c coding upstream 2091 13159988 ~ 13174477 (+)
XLOC_003329 CR847923.1 coding upstream 24183 13151919 ~ 13152385 (+)
XLOC_003328 zfyve9b coding upstream 88389 13058613 ~ 13088179 (+)
XLOC_003326 btf3l4 coding upstream 120761 13024002 ~ 13055807 (+)
XLOC_003327 ptgfr coding upstream 138335 13032483 ~ 13038233 (+)
XLOC_003332 NA coding downstream 3972 13193723 ~ 13194597 (+)
XLOC_003333 atp5f1b coding downstream 18147 13207898 ~ 13213059 (+)
XLOC_003334 abcb11b coding downstream 33874 13223625 ~ 13272085 (+)
XLOC_003335 si:dkey-13m1.2 coding downstream 177022 13366773 ~ 13413971 (+)
XLOC_003336 homer3b coding downstream 234025 13423776 ~ 13505942 (+)
XLOC_003318 CR450764.6 misc upstream 464572 12711700 ~ 12711996 (+)
XLOC_003317 CR450764.16 misc upstream 482305 12693967 ~ 12694263 (+)
XLOC_003316 CR450764.11 misc upstream 490969 12685304 ~ 12685599 (+)
XLOC_003315 CR450764.18 misc upstream 496540 12679732 ~ 12680028 (+)
XLOC_003314 CR450764.9 misc upstream 552717 12623555 ~ 12623851 (+)
XLOC_003369 CR854846.2 misc downstream 2933035 16122786 ~ 16123082 (+)
XLOC_003322 NA non-coding upstream 391509 12782215 ~ 12785059 (+)
XLOC_003319 NA non-coding upstream 458166 12718109 ~ 12718402 (+)
XLOC_003307 NA non-coding upstream 653539 12522770 ~ 12523029 (+)
XLOC_003304 NA non-coding upstream 682391 12493872 ~ 12494177 (+)
XLOC_003341 CR555295.2 non-coding downstream 627818 13817569 ~ 13817684 (+)
XLOC_003342 AL928649.1 non-coding downstream 675095 13864846 ~ 13864964 (+)
XLOC_003344 CT956066.1 non-coding downstream 891789 14081540 ~ 14082177 (+)
XLOC_003353 BX571942.1 non-coding downstream 1241522 14431273 ~ 14640317 (+)

Expression


Co-expression Network