XLOC_000035 (atp1a1a.4)



Basic Information


Item Value
gene id XLOC_000035
gene name atp1a1a.4
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007112.7
NCBI id CM002885.2
chromosome length 59578282
location 1689775 ~ 1706159 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00000063
GGAGCTTTTTGTCTCCGGAAGGGCTCTCAAGCGGACTACGACATCTGAAAGTCTGAGTTGGAATAATCCAGGAAAATGGGGCTTGGAACTGGAAATGATAAGTACAAACTGGCGGCAACTTCAGAAGATGAAGCCAAAGCgccaaaaaaagggaaaaagaagCAAAAGGACATGGATGAGCTTAAGAAAGAAGTGGATCTGGATGACCACAAGTTGACGCTAGACGAGCTTCACCGCAAATACGGGACTGACCTGACCAGGGGCTTGTCTTCCTCTCGTGCAAGGGAGGTCTTGGCTCGTGATGGACCCAATGCGTTGACTCCTCCACCAACCACTCCAGAATGGGTCAAGTTCTGCAAGCAGCTCTTTGGAGGATTCTCTACTCTCCTGTGGATTGGTGCCATCCTTTGTTTTCTTGCCTACGGCATCCAGGCGGCCTCTGAAGACGATCCCACGAATGACAATCTTTACCTGGGGATTGTGCTGGCTGGTGTTGTCATAATCACTGGATGCTTTTCATACTACCAAGAAGCCAAAAGCTCAAAGATCATGGAATCGTTTAAGAACCTTGTTCCTCAGCAAGCCCTGGTTGTGCGTGATGGAGAGAAAAAGAGCATCAATGCTGAGGAGGTGGTCGCTGGTGACCTTGTGGAGGTCAAAGGTGGAGACCGAATCCCAGCTGACCTTCGCATCATCTCTGCACATGGATGCAAGGTGGACAACTCTTCCCTCACTGGAGAATCTGAACCCCAGACTCGTACTCCTGACTTCTCCAATGATAACCCACTGGAGACCAGGAACATTGCGTTCTTCTCTACCAACTGTGTTGAAGGTACTGCCAGAGGAATTGTCATCAACACTGGTGACCGCACTGTCATGGGTCGCATCGCCACTCTTGCCTCCAGCCTAGAAGGTGGACAGACACCAATTGCTAAAGAGATTGAGCACTTCATCCACATCATCACTGGAGTGGCTGTCTTCTTGGGCGTGTCCTTCTTTATTCTTTCCCTGATTCTTGGATATGGGTGGTTGGAAGCCGTCATCTTCCTGATTGGAATTATTGTCGCCAATGTACCTGAAGGTCTCCTTGCTACTGTAACTGTGTGTCTGACTCTCACTGCCAAACGAATGGCAAAGAAGAACTGCCTGGTGAAGAATCTTGAAGCTGTGGAGACTCTTGGATCAACCTCTACCATTTGCTCTGACAAGACTGGAACTTTGACCCAGAACCGGATGACCGTCGCTCATATGTGGTTCGACAGCCAGATTCATGAAGCAGACACCACTGAGAACCAGAGTGGAACCACCTTTGACAGGAGCTCTCCTACGTGGTCTGCACTTGCACGTGTTGCTGGCCTTTGCAATCGTGCCGTCTTCCTAGCTGATCAGCGCAATGTGCCTATCCTCAAGAGAGACACAGCTGGTGATGCCTCCGAGTCTGCCCTCCTGAAGTGTATTGAGCTGTGCTGCGGTTCAGTCAATGAAATGAGAGAGAAGTACACAAAGATTGCAGAAATCCCTTTCAACTCCACCAACAAGTATCAGCTTTCAATCCACAAGAATCCCAATTCCTCAGAGCCAAAACACTTGCTTGTGATGAAGGGAGCACCTGAGAGGATCTTGGATCGATGCTCCACCATTTTAATTCAGGGAAAACAGCAGCCCTTAGATGAAGAAATGAAAGATGCTTTTCAGAATGCTTATGTTGAACTTGGAGGTCTTGGAGAAAGAGTCCTGGGTTTCTGCCACTTCTGCCTTCCTGATGATCAGTTTCCTGAGGGTTTTGCATTTGATACTGAAGAAGTGAACTTCCCCACTGAGAACCTGTGCTTTGTTGGCCTCATGTCCATGATTGATCCTCCTCGTGCCGCTGTACCAGATGCTGTGGGCAAGTGCAGGAGTGCTGGAATCAAGGTGATCATGGTTACTGGTGACCATCCAATTACAGCTAAAGCTATTGCAAAAGGTGTCGGCATCATCTCAGAAGGCAATGAGACTGTTGAAGACATTGCCGCTCGTTTGAACATCCCGGTTGGAGAGGTTAATCCAAGAGATGCGAAGGCATGTGTGGTCCATGGAGGAGAACTGAAAAGTATGAGTGAAGAAGAGCTAGATGATATCCTGAAACACCATACAGAAATTGTGTTCGCCAGAACTTCTCCACAACAAAAGCTGATCATTGTGGAAGGATGTCAGCGACAGGGTGCCATTGTAGCCGTAACCGGTGATGGAGTCAATGATTCTCCAGCTCTGAAGAAGGCTGACATTGGTGTGGCTATGGGTATTGCTGGATCTGACGTATCCAAGCAGGCTGCTGACATGATCCTTCTGGACGACAACTTTGCCTCAATTGTCACTGGAGTAGAAGAAGGACGTCTGATCTTTGATAACTTGAAGAAGTCCATTGCCTACACCCTGACAAGTAACATCCCTGAGATCTCACCTTTCCTTCTGTTCATCATTGCTAATATTCCTCTACCTCTGGGCACCGTCACCATTCTCTGCATTGACCTCGGCACTGACATGGTTCCTGCGATCTCGTTGGCCTATGAAAGTGCTGAAAGTGACATCATGAAGAGACAACCCAGAAATGCTAAAACAGATAAACTGGTGAACGAGAGGCTGATCAGTATGGCCTATGGTCAAATAGGTATGATGCAAGCAGTCGCAGGGTTCTTTTCCTACTTTGTAATTCTCGCCGAAAACGGATTCCTCCCCTCCGATTTAGTAGGAATCCGAGTCAACTGGGATGACAAATATGTCAATGATCTGGAAGACAGCTATGGCCAGCAATGGACATACGAGCGCAGAAAGATTGTGGAGTTCACATGCCACACAGCCTTCTTCGCCAGTATTGTGATTGTGCAGTGGGCAGATCTGATCATCTGTAAGACCAGGAGGAATTCCATTGTACAGCAGGGAATGAGAAACAAAATCCTCATCTTCGGCCTGTTTGAAGAAACTGCTCTTGCAGCATTTCTGTCCTACTGCCCAGGCATGGACGTAGCTTTGAGGATGTATCCGCTCAAACCGTGCTGGTGGTTCTGCGCCTTCCCATATTCACTTCTCATCTTCGTCTATGATGAAGCTAGAAGATATATCCTTAGGCGGAGCCCAGGAGGTTGGGTGGAACAAGAAACATACTACTAAAACATGAAGCAAACATTTTCAAGGAGACAcatatcaatatatttttaaatgatactgAATCTGGCCATTTTCAGTCAATAAAGCTGTTGAAGTGGA
>TCONS_00000064
AGAAGATGAAGCCAAAGCgccaaaaaaagggaaaaagaagCAAAAGGACATGGATGAGCTTAAGAAAGAAGTGGATCTGGATGACCACAAGTTGACGCTAGACGAGCTTCACCGCAAATACGGGACTGACCTGACCAGGGTGAGTTTAATATCAATTCTGGGGATCATTATGTGTCTAAAATGATTTAAATGCgtgtttaaatgtcttaaataattataatattattaaattttaaaaagtagaagAATAAAAACAGCTGGTACCGTGATTCATAATCACTGAGTGTAGTAATAATAACCTCAATATATCGTTCCAGTCAAATAACAGCAGATTTGGTTAAGAGTTGTTTAAGGCAAAACAGCAGATCCTCATGTATTGGAAACAGAAGATTATAGGCTGTCATATagaaactattaaataaaattaccTTAAGCCTTTGAATGCAAGTTTCAAGTCTGAACCCTAAGCGCATAATATTTAGGGTGAATTACTGTGAAGCACAGCTCCACCTACCTGGTCCAAACCAAACCCTCAGCCGTACTGTGACCTTCAGTATGCATCTCAAGGACAGCAAGGCCCCTTTTTATCATCTAATTAACTTTTTGTATGTGACTTTCGCCATTGACATCCATGCTTTTGAGTTTTCCTTGGCTTTTCAGGTATCTCACAACAATCTCCATACAGTCTCATAATCGTATTTAGAAATTGAGTAATCAGCTGAAGTCATCAGCTAATTATTGCTAgaattatttcaaatatttcctaaatgatgtttaacagagcaaagaattgttcacagtatttcctataatatattttcttctgaagaaagtcgtattagttttattttggctagaataaaagcagttgtacattattttaaagc
>TCONS_00000065
ggatggatggatggatggatagacagacggatagacagacggatagatggatacatTGAcaagcagatggatggatggatagatggatacataAACAaaaggacagacggatggacagacggatggacagacagacagacagatagatagatagatagatagatagatagatagatagatagatagatagatagatagatagatagatagatagatagatgtatagatagatagatagatagatagatgtatagatagatagatagatagatagatagatagatagatagatagatagatagatagatagatagatagatagatagatagatagatagatagatagatttggcAAAAGTCTTAGCCCCGCAAAGCTGGTGGTGGCTTGAGATATTTGCACAGTGCTATAATTAAACTGTATAATTTAAGGATTATTTTAAGGAGCACATCCTAATGTCCAACATTATTCTTTCTTAGAAACAAAATCCTCATCTTCGGCCTGTTTGAAGAAACTGCTCTTGCAGCATTTCTGTCCTACTGCCCAGGCATGGACGTAGCTTTGAGGATGTATCCGCTCAAACCGTGCTGGTGGTTCTGCGCCTTCCCATATTCACTTCTCATCTTCGTCTATGATGAAGCTAGAAGATATATCCTTAGGCGGAGC

Function


symbol description
atp1a1a.4 Predicted to enable P-type sodium:potassium-exchanging transporter activity. Predicted to be involved in cellular monovalent inorganic cation homeostasis and inorganic cation transmembrane transport. Predicted to act upstream of or within potassium ion transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including cardiovascular system; immature eye; integument; nervous system; and pronephros. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2DD. Orthologous to human ATP1A1 (ATPase Na+/K+ transporting subunit alpha 1).

GO:

id name namespace
GO:0006883 cellular sodium ion homeostasis biological_process
GO:1902600 proton transmembrane transport biological_process
GO:0036376 sodium ion export across plasma membrane biological_process
GO:0030007 cellular potassium ion homeostasis biological_process
GO:0006811 ion transport biological_process
GO:0006813 potassium ion transport biological_process
GO:1990573 potassium ion import across plasma membrane biological_process
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0005391 sodium molecular_function
GO:0005524 ATP binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0008556 potassium transmembrane transporter activity, phosphorylative mechanism molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-001212-4 Predicted to enable P-type sodium:potassium-exchanging transporter activity. Predicted to be involved in cellular monovalent inorganic cation homeostasis and inorganic cation transmembrane transport. Predicted to act upstream of or within potassium ion transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including cardiovascular system; immature eye; integument; nervous system; and pronephros. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2DD. Orthologous to human ATP1A1 (ATPase Na+/K+ transporting subunit alpha 1).

Ensembl:

ensembl_id ENSDARG00000001870

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00000063 False 3246 mRNA 0.48 22 1689775 1706159
TCONS_00000064 False 887 lncRNA 0.35 2 1690047 1691025
TCONS_00000065 True 664 lncRNA 0.38 2 1705130 1705880

Neighbor


gene id symbol gene type direction distance location
XLOC_000034 NA coding upstream 70461 1617203 ~ 1619314 (+)
XLOC_000033 urp2 coding upstream 75275 1599979 ~ 1614500 (+)
XLOC_000032 NA coding upstream 111524 1571847 ~ 1578251 (+)
XLOC_000031 NA coding upstream 328944 1358731 ~ 1360831 (+)
XLOC_000030 NA coding upstream 347538 1315289 ~ 1342237 (+)
XLOC_000036 atp1a1a.1 coding downstream 5981 1712140 ~ 1796832 (+)
XLOC_000037 atp1a1a.3 coding downstream 99135 1805294 ~ 1815660 (+)
XLOC_000038 atp1a1a.5 coding downstream 132005 1838164 ~ 1850104 (+)
XLOC_000039 si:ch211-132g1.6 coding downstream 190578 1896737 ~ 1899848 (+)
XLOC_000040 si:ch211-132g1.4 coding downstream 198260 1904419 ~ 1911381 (+)
XLOC_000029 CR450787.2 non-coding upstream 470970 1218691 ~ 1218805 (+)
XLOC_000043 NA non-coding downstream 295557 2001716 ~ 2005632 (+)
XLOC_000044 NA non-coding downstream 317250 2023409 ~ 2023645 (+)
XLOC_000049 CR352215.1 non-coding downstream 569446 2275605 ~ 2275742 (+)
XLOC_000051 CR352215.2 non-coding downstream 696944 2403103 ~ 2403224 (+)
XLOC_000053 NA non-coding downstream 2012507 3718666 ~ 3720603 (+)

Expression



Co-expression Network