XLOC_000357 (pcca)


Basic Information

Item Value
gene id XLOC_000357
gene name pcca
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007112.7
NCBI id CM002885.2
chromosome length 59578282
location 29862074 ~ 29953746 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00000610
CGCGCCGCTCTCCTCTCAGCAGCTCTCCGACTATCATGGCGGCTTACAGAAGCGCTGCAGGCTTTCAAAGAGTTTTGCATGATGTTAAGCATGTGTGTTTTAAGCAAAGGTGTGGTGTTATAATCTGCCGGTACTCTACTGTGATTGAGCCTAATGACAAGACCTTTGATAAAATCCTCATTGCAAACAGAGGCGAGATCGCCTGCAGGgTGATTAAAACATGTAGGAAGATGGGCATCAAGACGGTTGCAGTTCATAGTGATGTGGACTCCAGTGCGGTTCATGTGAAAATGGCAGATGAGGCTGTGTGTGTTGGTCCTGCTCCTACCAGTAAAAGTTACCTGAACATGGATGCTATCATGAATGCCATCAAGTTGACTGGAGCACAAGCTGTTCATCCAGGCTATGGATTCCTGTCTGAAAATAAGGAGTTTGCCAAAAGATTGGCGGCTGAGGGGGTGACCTTCATTGGTCCTGACACTCATGCCATCCAGGCAATGGGGGATAAGATCGAGAGCAAACTCATCGCCAAAGCTGCCAAAGTCAACACCATCCCTGGCTTTGATGGGGTGGTCAAGgaTGCAGAAGAGGCTGTGAAAATAGCAGGAGAGATTGGTTACCCTGTTATGATCAAAGCATCTGCTGGTGGAGGAGGTAAAGGGATGAGGATTGCATGGAATGATGAGGAAACCAGGGAAGGCTTTCGTTTCTCTTCTCAGGAGGCGGCATCTAGTTTTGGAGATGACCGTTTGCTGATTGAGAAGTTTATAGACAATCCCAGACATATTGAGATTCAGGTGTTGGCGGACAAACACGGCAATGCTCTGTGGCTGAATGAGAGAGAGTGCTCTATCCAGAGAAGAAACCAGAAAGTGGTAGAGGAGGCACCCAGCACTTTTCTGGACCCAGACACCCGGAGAAAAATGGGCGAGCAGGCTGTGTCTCTGGCAAAAGCAGTGAAATACTCTTCAGCTGGCACTGTGGAGTTTCTTGTTGACTCTAAGAAGAACTTCTACTTCTTGGAGATGAACACACGTTTGCAGGTGGAACACCCCATCACAGAGTGCATCACAGGGCTGGATCTTGTGGAGCAGATGATCCGCATCGCAAAGGGAAACAAACTTCAACACAAACAGTCTGACATACCCATAAATGGCTGGGCCATCGAGAGCAGAGTCTATGCTGAGgaTCCATACAAATCATTTGGACTCCCCTCCATCGGTCGACTGTCTCAGTACCAGGAGCCACTTGACTTGGATAATGTTCGAGTGGACAGCGGAATTCAAGAAGGAAGCGACATCAGTATTTATTATGACCCTATGATTTCTAAGcTGGTCACGTATGGCAAAACACGGGAGGAAGCTCTGAAGAAAATGGAAGAAGCACTTGATAATTACGTGGTCAGAGGTGTAACACATAACATACCTCTACTGAGAGAGATCATTGTTCATCCTCGGTTTGTGTCTGGTGATATCAGTACTAAGTTTCTCCCGGAGGTGTATCCTGATGGGTTCAAAGGTCACATGTTAACAGCAGGAGAAAGACAGGAGCTGCTTGCTACGGCTGCGGCACTCTATACAGCAGCACAGCTCCGCTCTCAGAGGTTCCTGGGGGATCTCAGGGTGTCTTGTGTTCCTGCAGAGAGCAGTGATTGGGAGTTGTGTGTAGAACTTGAGAAAAGTGTTCACATGCTGGGCGTGTCTCGGTCTGGAAACAAATATACAGTGGAGATAGATGGAGAAAAGGTTCAAGTGTCTGGAGAATGGAACTTGGCCTCAGCATTGCTGTCCGTCACCATCAACGGCAAACACAGGACTCTTCAGTGCCTGTCACGGACAGCGGCTGGAGAAATCATCTTGCAGTATCTGGGCACTTCATTTAAGTTGCGTGTGCTGAGTAAACTGGCAGCGTCTCTCAGTAAACACATGCCGGAGAAGGTTCCAGAAGACACCAGCAGCATCCTCCGCTCTCCAATGCCAGGATCTGTGGTGGCGGTATCCGTTAAACCAGGGGATACGgTTGCAGAGGGACAGGAGATCTGTGTGATTGAAGCTATGAAGATGCAGAACAGCATGACCGCAGCCAAGACGGCCAAGGTGAAGAGCGTGCATTGTAAAGCTGGAGATACAGTTGGAGAAGGAGATTTACTGGTGGAACTGGAGTAACATCTCATCTGCAGGCATTAAAAAGGCCATCAGTTGCTGTGGATGAGGAAACAAAGACACTAATAGAGTAGATGGAACATTCCTCCACATGTCCTTTGTTCCCCTGTGGTCTCTTTTTTACATTATGACTGTAATACATCCATCTCACTGGAACTGCTTTATTCCAGGGAAAGAAATGTCAAAGCGATAACATTCTCTTGTGCCTTGGCCTTCCATTGGAGGTTTTCTTGTTTCACATGGAATCAACCACAGTTTGACATCATCATTTGTGATTGTTTTAACGTATCTTTAAATACAGTCAACGAAAACTGTTGACACACTCCTTCCCCCTCACCTCGGTGCACATTTAGCATTGTTCAGAGGAAGTGCTGTGAATGTTTGCCATTGCTCCAACtcagttattttaattattaggtTGTTGTATGCAATGAATTTTTCTGTTACATGATTATGCAAACACAAGTGTTAATATATATCTTTCACCTACCAATCACCATCAATCCCACACTCGTGTATATTTATACCACACATATTTCTGTCATCAAATGCATTAAATTGGTCAAGAGAATAATATGCCTACATGCATTTGTGGTTTGTTTCTGCACAAGTTGGGTTTAAGTCTGTAGGTGTGCTATAGAGACAGTTTATTTGTTTCCACAATTCAAATAGAGAAACCCAGAGGAGTGGACCATTAAAAGATGGGAAAGGAAGATAATATTATGAAAACTAACAGCCAGCTGTGATCAGGCTTGGATATTGTTGCTGGTTCCTGTTTATGTAGCACAAAGCCACTTACTGTCTGTATTTGTATtgagaaaatggaataaaatggGATTAATGTAAAC
>TCONS_00000611
TCTCCTCTCAGCAGCTCTCCGACTATCATGGCGGCTTACAGAAGCGCTGCAGGCTTTCAAAGAGTTTTGCATGATGTTAAGCATGTGTGTTTTAAGCAAAGGTGTGGTGTTATAATCTGCCGGTACTCTACTGTGATTGAGCCTAATGACAAGACCTTTGATAAAATCCTCATTGCAAACAGAGGCGAGATCGCCTGCAGGgTGATTAAAACATGTAGGAAGATGGGCATCAAGACGGTTGCAGTTCATAGTGATGTGGACTCCAGTGCGGTTCATGTGAAAATGGCAGATGAGGCTGTGTGTGTTGGTCCTGCTCCTACCAGTAAAAGTTACCTGAACATGGATGCTATCATGAATGCCATCAAGTTGACTGGAGCACAAGCTGTTCATCCAGGCTATGGATTCCTGTCTGAAAATAAGGAGTTTGCCAAAAGATTGgaTTCCAGATTTCTTCTGCCAGATTTCTTCTTTTCGTGGA
>TCONS_00000612
GGCTTTCAAAGAGTTTTGCATGATGTTAAGCATGTGTGTTTTAAGCAAAGGTGTGGTGTTATAATCTGCCGGTACTCTACTGTGATTGAGCCTAATGACAAGACCTTTGATAAAATCCTCATTGCAAACAGAGGCGAGATCGCCTGCAGGgTGATTAAAACATGTAGGAAGATGGGCATCAAGACGGTTGCAGTTCATAGTGATGTGGACTCCAGTGCGGTTCATGTGAAAATGGCAGATGAGGCTGTGTGTGTTGGTCCTGCTCCTACCAGTAAAAGTTACCTGAACATGGATGCTATCATGAATGCCATCAAGTTGACTGGAGCACAAGCTGTTCATCCAGGCTATGGATTCCTGTCTGAAAATAAGGAGTTTGCCAAAAGATTGGTTGTCGACTGGATTGGTGTAGAGGACACCTTTCAATTTGGCTGTTATGCTGCAGCGAATGAGTCAGAA

Function

symbol description
pcca Predicted to enable propionyl-CoA carboxylase activity. Predicted to act upstream of or within lipid catabolic process. Predicted to be active in mitochondrion. Is expressed in several structures, including alar plate midbrain region; immature eye; liver; optic tectum; and segmental plate. Human ortholog(s) of this gene implicated in amino acid metabolic disorder and propionic acidemia. Orthologous to human PCCA (propionyl-CoA carboxylase subunit alpha).

GO:

id name namespace
GO:0005739 mitochondrion cellular_component
GO:0016421 CoA carboxylase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0016874 ligase activity molecular_function
GO:0004658 propionyl-CoA carboxylase activity molecular_function

KEGG:

id description
ko00620 Pyruvate metabolism
ko00630 Glyoxylate and dicarboxylate metabolism
ko00640 Propanoate metabolism
ko00061 Fatty acid biosynthesis
ko00280 Valine, leucine and isoleucine degradation
ko03110 Chaperones and folding catalysts

ZFIN:

id description
ZDB-GENE-040718-246 Predicted to enable propionyl-CoA carboxylase activity. Predicted to act upstream of or within lipid catabolic process. Predicted to be active in mitochondrion. Is expressed in several structures, including alar plate midbrain region; immature eye; liver; optic tectum; and segmental plate. Human ortholog(s) of this gene implicated in amino acid metabolic disorder and propionic acidemia. Orthologous to human PCCA (propionyl-CoA carboxylase subunit alpha).

Ensembl:

ensembl_id ENSDARG00000028982

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00000610 False 3010 mRNA 0.45 23 29862074 29953746
TCONS_00000611 False 478 mRNA 0.45 7 29862082 29876024
TCONS_00000612 True 456 mRNA 0.44 7 29862133 29876644

Neighbor

gene id symbol gene type direction distance location
XLOC_000356 zic2b coding upstream 1179 29831759 ~ 29860895 (+)
XLOC_000355 tm9sf2 coding upstream 37699 29798140 ~ 29824375 (+)
XLOC_000354 zc3h13 coding upstream 64167 29766725 ~ 29797907 (+)
XLOC_000353 cpb2 coding upstream 98014 29759678 ~ 29764060 (+)
XLOC_000352 raph1b coding upstream 118434 29664336 ~ 29743640 (+)
XLOC_000358 NA coding downstream 120889 30074635 ~ 30079529 (+)
XLOC_000359 vps8 coding downstream 129832 30083578 ~ 30310689 (+)
XLOC_000360 dre-mir-740 coding downstream 212207 30165953 ~ 30166065 (+)
XLOC_000361 BX255890.2 coding downstream 273645 30227391 ~ 30227505 (+)
XLOC_000362 tmem41ab coding downstream 468397 30422143 ~ 30438036 (+)
XLOC_000350 CR774189.1 non-coding upstream 353601 29507647 ~ 29508473 (+)
XLOC_000349 NA non-coding upstream 361040 29500308 ~ 29501034 (+)
XLOC_000348 CT573186.2 non-coding upstream 409341 29451465 ~ 29452733 (+)
XLOC_000347 CT573186.1 non-coding upstream 416355 29444452 ~ 29445719 (+)
XLOC_000346 BX908780.2 non-coding upstream 549515 29311527 ~ 29312559 (+)
XLOC_000365 BX548015.2 non-coding downstream 900223 30853969 ~ 30859524 (+)
XLOC_000369 NA non-coding downstream 1187373 31141119 ~ 31144527 (+)

Expression


Co-expression Network