LOC110499310 (epas1)



Basic Information


Item Value
gene id LOC110499310
gene name epas1
gene type coding
species rainbow trout (Oncorhynchus mykiss)
category of species economic fish

Chromosome Information


Item Value
chromosome id NC_048584.1
NCBI id CM023238.2
chromosome length 46616863
location 29285885 ~ 29356101 (+)
genome version USDA_OmykA_1.1_2020_rainbow_trout_Genome

Sequence


>XM_036956132.1
GGTCAGATTGACGCGTGAGCGACTGTCAACGGGCCAGCTGAGCGCAAAAGAGTGAACAGCGAACCGTGCTAGAAGTTCAGTAGACCAGCACAACCAACGCAACGAAGGAAACTTTGACAGCGGACCCTATTTTATCCAACTTCTAAAGCATTTGTAGGCTAAAGGTTGTGGATTGTAGGCCTACCTTTAGTGAATCGGTGAAAAGGCTGTACAATCCTTGGCAGTGTTCTGAGACTGTACAGCTGCCTACTGCTTCTGAAAGACAACTTGCATCTGAAATGGACTGTGCGTAAAGAGCAGATAAATTACTTCATCTCGATTTGACTTTCAATATTTTTCATTGTGTATGTTATTTGTTACTTGAAAATTGTTGCGTAAGTGGACTGATTCGGACTTTCGGGGAAATTCCATTTGTCACTGAACTTTGCAAAAGAAAACATGACGGCTGATAAGGACAAGAAAAGTTCGGAACGGCGGAAGGAGAAGTCTCGTGACGCGGCACGCTGTCGTCGTAGTAAGGAGACAGAGGGGTTCTACGAGCTGGCCCATCAGCTGCCCCTCCCACACAGCGTCAGCTCCCACTTGGACAAAGCCTCCATCATGAGACTGGCCATCAGCTTCCTGCGCACCCGCAAGGTCGTCGGCCCAGGCTGCTCCAACGGTGCAGAGACtgaggaggacagacagacggacagtaTGTATTTGAAGTCACTGGAGGGGTTTGTCACTGTGGTTACATCAGACGGCGACATGATCTTCCTCTCAGAAAACATCAACAAGTTCATGGGCTTAACACAGgtAGAGTTGACTGGACAAAGCATCTTTGACTTCACCCACCCCTGCGACCACGATGAGATTCGCGAGAACCTGAGTCTGAAAAATGGCACTGGGAAGAAGGGGAAAGCCTTGAGCACTGAGAGAGACTTCTTCATGAGGATGAAGTGCACAGTGACAAACCGTGGACGCACTGTCAACCTGAAATCAGCCAGCTGGAAAGTTCTGCACTGCACTGGCCACCTGAAGGTGTACAACAGTTGCGCCCCTCATGGGCTGTGTGGGTTCAAGGAGCCTCCTCTCACCTGCCTGGTGATGATGTGTGAGCCCATCCCCCACCCCTCCAACATCGACACGCCCCTGGACAGCAAGACCTTCCTGAGCCGCCACAGCATGGACATGAAGTTCACCTACTGCGACGACAGAGTCACTGAGCTGATGGGCTACAGTCCTGAAGATCTGCTGGGCCGCTCTGTCTATGAGTTCTACCACGCTTTGGACTCTGACAGTGTCACCAAGAGCCACCAGAACCtgtGCAGTAAAGGTCAGGCAGTGAGTGGACAGTATCGAATGCTGGCCAAACATGGAGGCTACGTgtgggttgagacccagggcacAGTCATCTACAACAGCCGGAATTCCCAGCCGCAGTGCATCGTTTGTGTCAACTACGTCCTCAGTGACGTGGAGAACAAGTCCATGATCTTCTCCATGGACCAGACTGAGTCTCTGTTCAAGCCACACCACATGAACAGTTTCTTCACCCAGAGTGGTGCTGCGGTGGCCGCGGAGCCCATCAAGACCCTGTTCACCAAACTCAAAGAGGAGCCAGAAGACCTTGCTCAGCTGGCTCCCACACCTGGAGACGCCATCATCACCCTTGACTTTGGAAGGCCACCGTTTGAGGAGCCTCATCCTCCTCTTTACCCCAAGATGTCTCCCATGCCCCCTCCGGCCCCCCAGGGCTGGGGCAGTGATGCCCACAAGCCCTGCCCGGCAGGAGACATGTCCAACCACATGGCTGCCaccttctcactgccccagaacCCCACACCAGGCAGTGCCACCCCCAGCACTGCCCCCCCTAGCCTGAGCAGTTGTTCCACGCCCAGCAGCCCAGGGGATTactacagcgagagagagagtgacctgAAGGTAGAGCTGACTGAGAAGCTCTTTGCTCTGGACACAGAGGGGCCCAAGAGCCCCGGCAGCACCCAGTCGGTCCTGAGTGATTTGGATCTGGAGACCCTGGCTCCCTACATCCCCATGGACGGAGAAGACTTCCAACTCCACCCCATCATTACTGAAGAGGCCCCTGGAGGCACCGAGGGGGCCGCTGACCAAATGGGACACCGCACCACACAGAACGGGTTCAGCAACATCGCCAGTCTCTTCCAGCCCCTGGGATCCCCACAGTCTGCCCACTACCAGCCCGCCAAGTGGGCCCCAGGAGACAAGAGAGGCCCCAACCACAGTGAAATAAGCCCCATGGACTCCAGGCCTACTCTGCCCTACACAGGCCCTGCACAGATCACCCCCTACCACACCCTAGCCAGCACCCCTTTGTCCTCCATGGGCGGACGTCAGAACCTGCAGTGGCCCCCCGATCCCCCGTTACACTACCAACAACAAGTGGACGCCATGGGCGGAAGCAACTCATGTCAGAACATGCCGGTCAACAGGATGCACAAGCAGAGGTCAATGGAGAACTTTGTCCAGGCCTACAGAGACATGAGTCCTGCTAGAATCGCCATAGCCAACAACTTCAAGCGTTCCTTCACGCAAATGGCAGTGGGTGACTCCACCCTGAGTACGCCATCAGAGATGATGTGGAAGAGGATGAGGAATGAAAGCTGTGCCATCCTGGATAGATCTCTCAGCACCAGCTCACTGGCAGATAAAGGTATGTGCATACATGGGGGTGTTGACCAGTGTCTCAGCCCCCTTCAACGGCACAGGAAGTCCCAGTATCCAGGATGTGGAAACAGTGCACCTAAAAAAGCCTTCCCCGAACAGTGGTGCAACTACAGAGAATACCGTATGCTGCCCTCTCCCAAAACAGAGGgggttGCCAGTCGGCTGTTGGGCCCGTCCTTTGAGACCTATTGTCTGCCAGAGCTCACCCGCTACGACTGCGAGGTCAATGTCCCTCTCCAAGGCAACCTGCACTTGCTGCAGGGCAGTGACCTACTGAGAGCCTTGGACCAGGCCACCTAG
>XM_036956131.1
GTCAGATTGACGCGTGAGCGACTGTCAACGGGCCAGCTGAGCGCAAAAGAGTGAACAGCGAACCGTGCTAGAAGTTCAGTAGACCAGCACAACCAACGCAACGAAGGAAACTTTGACAGCGGACCCTATTTTATCCAACTTCTAAAGCATTTGTAGGCTAAAGGTTGTGGATTGTAGGCCTACCTTTAGTGAATCGGTGAAAAGGCTGTACAATCCTTGGCAGTGTTCTGAGACTGTACAGCTGCCTACTGCTTCTGAAAGACAACTTGCATCTGAAATGGACTGTGCGTAAAGAGCAGATAAATTACTTCATCTCGATTTGACTTTCAATATTTTTCATTGTGTATGTTATTTGTTACTTGAAAATTGTTGCGTAAGTGGACTGATTCGGACTTTCGGGGAAATTCCATTTGTCACTGAACTTTGCAAAAGAAAACATGACGGCTGATAAGGACAAGAAAAGGAGCAGTTCGGAACGGCGGAAGGAGAAGTCTCGTGACGCGGCACGCTGTCGTCGTAGTAAGGAGACAGAGGGGTTCTACGAGCTGGCCCATCAGCTGCCCCTCCCACACAGCGTCAGCTCCCACTTGGACAAAGCCTCCATCATGAGACTGGCCATCAGCTTCCTGCGCACCCGCAAGGTCGTCGGCCCAGGCTGCTCCAACGGTGCAGAGACtgaggaggacagacagacggacagtaTGTATTTGAAGTCACTGGAGGGGTTTGTCACTGTGGTTACATCAGACGGCGACATGATCTTCCTCTCAGAAAACATCAACAAGTTCATGGGCTTAACACAGgtAGAGTTGACTGGACAAAGCATCTTTGACTTCACCCACCCCTGCGACCACGATGAGATTCGCGAGAACCTGAGTCTGAAAAATGGCACTGGGAAGAAGGGGAAAGCCTTGAGCACTGAGAGAGACTTCTTCATGAGGATGAAGTGCACAGTGACAAACCGTGGACGCACTGTCAACCTGAAATCAGCCAGCTGGAAAGTTCTGCACTGCACTGGCCACCTGAAGGTGTACAACAGTTGCGCCCCTCATGGGCTGTGTGGGTTCAAGGAGCCTCCTCTCACCTGCCTGGTGATGATGTGTGAGCCCATCCCCCACCCCTCCAACATCGACACGCCCCTGGACAGCAAGACCTTCCTGAGCCGCCACAGCATGGACATGAAGTTCACCTACTGCGACGACAGAGTCACTGAGCTGATGGGCTACAGTCCTGAAGATCTGCTGGGCCGCTCTGTCTATGAGTTCTACCACGCTTTGGACTCTGACAGTGTCACCAAGAGCCACCAGAACCtgtGCAGTAAAGGTCAGGCAGTGAGTGGACAGTATCGAATGCTGGCCAAACATGGAGGCTACGTgtgggttgagacccagggcacAGTCATCTACAACAGCCGGAATTCCCAGCCGCAGTGCATCGTTTGTGTCAACTACGTCCTCAGTGACGTGGAGAACAAGTCCATGATCTTCTCCATGGACCAGACTGAGTCTCTGTTCAAGCCACACCACATGAACAGTTTCTTCACCCAGAGTGGTGCTGCGGTGGCCGCGGAGCCCATCAAGACCCTGTTCACCAAACTCAAAGAGGAGCCAGAAGACCTTGCTCAGCTGGCTCCCACACCTGGAGACGCCATCATCACCCTTGACTTTGGAAGGCCACCGTTTGAGGAGCCTCATCCTCCTCTTTACCCCAAGATGTCTCCCATGCCCCCTCCGGCCCCCCAGGGCTGGGGCAGTGATGCCCACAAGCCCTGCCCGGCAGGAGACATGTCCAACCACATGGCTGCCaccttctcactgccccagaacCCCACACCAGGCAGTGCCACCCCCAGCACTGCCCCCCCTAGCCTGAGCAGTTGTTCCACGCCCAGCAGCCCAGGGGATTactacagcgagagagagagtgacctgAAGGTAGAGCTGACTGAGAAGCTCTTTGCTCTGGACACAGAGGGGCCCAAGAGCCCCGGCAGCACCCAGTCGGTCCTGAGTGATTTGGATCTGGAGACCCTGGCTCCCTACATCCCCATGGACGGAGAAGACTTCCAACTCCACCCCATCATTACTGAAGAGGCCCCTGGAGGCACCGAGGGGGCCGCTGACCAAATGGGACACCGCACCACACAGAACGGGTTCAGCAACATCGCCAGTCTCTTCCAGCCCCTGGGATCCCCACAGTCTGCCCACTACCAGCCCGCCAAGTGGGCCCCAGGAGACAAGAGAGGCCCCAACCACAGTGAAATAAGCCCCATGGACTCCAGGCCTACTCTGCCCTACACAGGCCCTGCACAGATCACCCCCTACCACACCCTAGCCAGCACCCCTTTGTCCTCCATGGGCGGACGTCAGAACCTGCAGTGGCCCCCCGATCCCCCGTTACACTACCAACAACAAGTGGACGCCATGGGCGGAAGCAACTCATGTCAGAACATGCCGGTCAACAGGATGCACAAGCAGAGGTCAATGGAGAACTTTGTCCAGGCCTACAGAGACATGAGTCCTGCTAGAATCGCCATAGCCAACAACTTCAAGCGTTCCTTCACGCAAATGGCAGTGGGTGACTCCACCCTGAGTACGCCATCAGAGATGATGTGGAAGAGGATGAGGAATGAAAGCTGTGCCATCCTGGATAGATCTCTCAGCACCAGCTCACTGGCAGATAAAGGTATGTGCATACATGGGGGTGTTGACCAGTGTCTCAGCCCCCTTCAACGGCACAGGAAGTCCCAGTATCCAGGATGTGGAAACAGTGCACCTAAAAAAGCCTTCCCCGAACAGTGGTGCAACTACAGAGAATACCGTATGCTGCCCTCTCCCAAAACAGAGGgggttGCCAGTCGGCTGTTGGGCCCGTCCTTTGAGACCTATTGTCTGCCAGAGCTCACCCGCTACGACTGCGAGGTCAATGTCCCTCTCCAAGGCAACCTGCACTTGCTGCAGGGCAGTGACCTACTGAGAGCCTTGGACCAGGCCACCTAGACCCAGCCCTACACCCTCTACTGCATTTCCCTACCCTGGACCAGGCCACCTAGACCCAGCTCTACACCCCCTACTCCCCTACCCTACCCCCCTCTGGACCAGGCCACCTAGACCCAGCCATACACCCCCTACTCCCCTACCCTACCTTCCTCTGGACCAGTTCACCTAGACCCAACCCTACACCCCCTActcccctaccctaccctcccctGGACAAGGCCACCTAGACCCAGCACTACACCCCCTACTCCCCCACCCACCTACCCTACCCAGCCCTGGACCAGACCTCCGAGACGCAGACATATACCCCCTCCCGTACTTTATCTTACCCTACCCTACCTAGACATAGCCCTCACCAACCTCACCTCTACCCATCCTTACCCTCCAATAGTCTTAGCCAATACACCCTAGACTAACACATCTCTACAACACTGACTGACACCTCAGCCAAGCCGCCTCCCCTGTCCTAACGTCCTGGCACATCTAACATAGTACTACTCCACCAtgccccacccacccaccctacCATACCAAGCCCCATACAAACCTGTTTCATCGTCAAAGCCACACATACCCTGCCTCCTCCTCATCCATCCACCCTACTGCCCCTATGTATCATTAGAAAAACGTGTGGCTTCTGTTCTATTTTTGTTGTCTTTATCATCATAAATTATATACGTGTATAATTCTTAGTTATTAGTCTATTTCTGTTAAACGATTTGATCTGTTTCAGTGTTCCCAAGCTCTATTCTGTCCTCCCAATTGTGTGATCTGTAGCCTACTTTTCTTCTTtcaccatgtctgtctgtctgtctgtctgtctgtctgtctgtctgtctgtctgtctgtacgacGCTGTCATAGACACACTAACAAACAAAACAGTCTGAAATCCAGATTAAACTTCACCGAATGTAAGCATAACATCcaggttttttttaaataaacgttTTTGTTGTTCTTTTACTACCCTTTCCCCATTCCTTACTGTCTAGTTTCCTTCAGTCACTGGTGTCTGTTTGCATGTTTCTATTGTTCCCTCAGTGTGAGCTCACTGGATAGTTACAGTGCTTGCCATGAAGTTGATTGGTCAAATCAGAGCGTGCCCCCAACATAGGGAGGAGAGTGCTATTTTTGGTACCTTTTTCATGGCATTAGAAGTCATATCAGAATCAGAGAGACTTTGGCCTAGATCACAGGAGGGTGGTgacgggaggacggctcataataatgactgtaaTGAAGTGAATGAGATGGTATCAAACACAataaaaccatgtgtttgatgtgtcaATACCATTTCATTcatttcattccagccattactatgagcccattCACTCCAATAAAGGTGCCAGCAGCCACCTGTGGCCTAGATTCACTAAGATCAAGCGTTAACCAGTGATAGCCGACACCCGCACAGCTGGCGTTTTAGCCGTGTCGCAGGTTTAACTGCGTTGCAGCTGTTAAGTAAGAGACGTTGCTCGTGTGgtcattgtcacgaagccacaccgGTCCCACTCGCATTACAAGTTCAGAATGAGTAAGTCTAGGCTATATAGAAATTACATGACACTCAAATTGAGAATCATTAAACTAAATAATtaggatttctatcagcctaatcgaGGTGTAAATTAAATATCGCATTCCAGTGTTTGAACTTGTAAACAAGTTGTAAACAAGGTTGCATGGGATTTTTCTTAATGCGACTCCGTgtagccaatggcaatgtcctcctttaggtataatgccgggAGCCGCCTGTGGATTTGAACACTTCCTTAGTTTAAGAGATGGCAACTCGCTATTGACATTGAGACTCTTTTTCTgtattctctttctttctatttcATTCTCATTTTTAGGTCTTTGTCTTTGTGTGGTGACCACTTAAAAGTTTGAATTTAGCTTCGTACACACATATATGTATTTAAAGACAGAAGCTATAAAGTTTCTACTATAATGTCAAGATAGTGTTTTAGTGTTTATGTGCCTTGGTACTTTGTCTTATCTACCCAGTAGATGCAGATTGTATTCCTGTGTTTTAGATGTTACTCCATAGTGCTGGtgtctgttttgttttttgttttttccaGAGTGTATGCACAAGTATAATGAAATTGTTAGCAGGCCAGTACTGATCTGTTGTTGCGCTTTAAAGAAAAAAGAAAATGGAGAGGGAAAAAACGATAACATTTTCTAAGTTCCACTTTTGACATGTAGCATTTTGAATATTGTAAACAAAAGAAATTGACACAAAAGTAATATCTTTCAACAGTATCTAAACAGGTGATGGTGCTTTATAGATATAACCATCTTGCATTTGTAGAGGCAACTTTATATGTTTCATGGATCCACTTTCAGTAACACTGTATTTTGATGCTATTATTCATTTTTCTTGCTGAGATTGTCTTTAAAGGTGATTCATAACAGACATGATGTGCCTTAACATTGCCTTAAGGTTGTCCCAATGTTGATTCAGCCCAGTGTTATGCCCTTCAAAATGCACAGATTGTAGACGTAGACGTACAGTAGATTGTCCTATAAAACTACACTAGC

Function


symbol description
epas1 Enables DNA binding activity; protein heterodimerization activity; and transcription coactivator binding activity. Contributes to sequence-specific DNA binding activity. Involved in cellular response to hypoxia; positive regulation of transcription by RNA polymerase II; and regulation of protein neddylation. Acts upstream of or within response to hypoxia. Part of transcription regulator complex. Implicated in familial erythrocytosis 4; lung non-small cell carcinoma; polycythemia; and pulmonary hypertension. Biomarker of osteoarthritis; pre-eclampsia; psoriasis; rheumatoid arthritis; and von Hippel-Lindau disease.

NR:

description
endothelial PAS domain-containing protein 1 isoform X1

GO: NA

KEGG:

id description
K09095 HIF2A, EPAS1; hypoxia-inducible factor 2 alpha

RNA


RNA id representative length rna type GC content exon number start site end site
XM_036956132.1 False 2994 mRNA 0.55 16 29285885 29353539
XM_036956131.1 True 5561 mRNA 0.49 16 29285886 29356101

Neighbor


gene id symbol gene type direction distance location
LOC110499309 prkce coding upstream 5255 29127739 ~ 29280630 (+)
LOC110499307 NA coding upstream 349233 28892178 ~ 28936652 (+)
six3a six3 coding upstream 433557 28849051 ~ 28852328 (+)
camkmt camkmt coding upstream 540304 28548493 ~ 28745581 (+)
slc3a1 slc3a1 coding upstream 751297 28525469 ~ 28534588 (+)
trnaa-ugc-146 NA coding downstream 34219 29390320 ~ 29390393 (+)
ankrd1a LOC106589708 coding downstream 67593 29423694 ~ 29428859 (+)
lhcgr lhr coding downstream 81256 29437357 ~ 29458499 (+)
mertka LOC106589725 coding downstream 113930 29470031 ~ 29508296 (+)
tmem87b LOC106589726 coding downstream 154760 29510861 ~ 29536419 (+)
G1682169 NA non-coding upstream 88705 29196652 ~ 29197180 (+)
G1682164 NA non-coding upstream 97293 29186781 ~ 29188592 (+)
G1682128 NA non-coding upstream 163357 29121845 ~ 29122528 (+)
G1682122 NA non-coding upstream 170640 29114854 ~ 29115245 (+)
G1682118 NA non-coding upstream 174632 29110719 ~ 29111253 (+)
G1682426 NA non-coding downstream 4632 29360733 ~ 29361016 (+)
G1682427 NA non-coding downstream 6735 29362836 ~ 29363209 (+)
G1682440 NA non-coding downstream 26295 29382396 ~ 29382601 (+)
G1682418 NA non-coding downstream 39714 29395815 ~ 29396294 (+)
G1682489 LOC106589727 non-coding downstream 185251 29541352 ~ 29543464 (+)
G1681792 NA other upstream 507476 28778006 ~ 28778409 (+)
G1681180 NA other upstream 559390 28717361 ~ 28726495 (+)
G1680230 NA other upstream 1910066 27375354 ~ 27375819 (+)
G1679823 NA other upstream 2198422 27084426 ~ 27087463 (+)
G1679135 NA other upstream 2510205 26700392 ~ 26775680 (+)
LOC110499316 LOC106589729 other downstream 216334 29572397 ~ 29588171 (+)
G1686317 LOC106589755 other downstream 3298253 32654354 ~ 32661648 (+)
LOC118942060 LOC106589768 other downstream 3821192 33177293 ~ 33196167 (+)
G1687675 NA other downstream 4969736 34325837 ~ 34326254 (+)

Expression



Co-expression Network