gclc (gsh1)


Basic Information

Item Value
gene id gclc
gene name gsh1
gene type coding
species rainbow trout (Oncorhynchus mykiss)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_048584.1
NCBI id CM023238.2
chromosome length 46616863
location 34583316 ~ 34591320 (+)
genome version USDA_OmykA_1.1_2020_rainbow_trout_Genome

Sequence

>XM_021576493.2
AACGTCATAGATgtacagattgctataacatataaTGTAGTTAGCTGATGTGTAAAATATCTCTccgggcgttgtaagatctgtcagACAAAGCATAGGAAACGTCTGAGCGGACAAACGCGCCCACAGTCACACGTGTTCAGTCACTGTGAGTGTGAAGAGTACAAGGAAGGAAATTTTGTTCACTCGGTGTTGCACACTGAAACAGAGGATTCTTGGCTAGTCGAGTCAATTGACCGGTCCTCACTATATAGAAGTGATTCCATCAAGGAAAATATATTTAGGTGTAGGTGCTGAATTAGATCGGTATTGCTGGGGGGACAACCTTGGCATTATTATTGGCGCTTGGGACATTGTGTCAGCGGGTAATTTTAATAGCTTGCTAGCTCGCTAGATAACAAGAGATGTGTGAAGGCCTCCCTTGTTGGCTAGCTAATAAGTATCCACCGTTACAGTGAAAATAGCAAGACCATTGTTGGTTTGGTTCAAGTTCTGTTTTGTTGACAGTAGCTACGTCGCTGAACTTCGATAACACGTTAGCGAGCAACAATTATAGATAGCTAAACAAAATAGCAAACGCCAGTCTCGCTGTCGGTGCCGAACTCTTGCGATATGGGCTTGCTGTCAAAAGGGTCACCGCTCAACTGGGAAGAAACCAAAAAGTATGCAGACCATGTTCGGAAACATGGCATCGTTCAGTTTCTCAACATCTATAACAAGGTGAAAGAACGACAGAAAGATGTGTTATTATGGGGCGATGAGGTGGAatacatgttgatagaaatggaTGAGAAAAATGGAAAGGTTCGTCTTGTTCTCAATGGTGGGGAGGTTTTGGAAACCCTTCAAGACAAAGGAGAAAAGACCAACCCCAACCATCCTACCCTTTGGAGGCCAGAGTATGGCAGCTACATGATCGAAGGGACTCCGGGGCAGCCCTATGGTGGGACAATGTCAGAGTTCAACACAGTGGAGGACAACATGGGGAAGCGAAGGAGAGAGGCCTCATCTGTGCTGAATAAGAATGAAACGCTTGCCACCATCACGTCATTCCCAAGGTTAGGCTGCCCAGGCTTCACACAGCCAGAATACAAGCCAACACCTGTTGAAAAGGGAGTGTCAAAATCACTGTTCTTCCCAGATGAAGCCATAAACCAACACCCAAGATTCAGCACCCTGACCAGAAACATTCGtcacagaagaggagagaaggtggtGATCAACGTACCCATCTTTAAAGACAAATGCACCCCATCTCCATTTGTGGAGAAGTTTCCGGAAGACGATGGGGAGGCTGCCAGGGCAGCTCTACCTGATCACATCTACATGGATGCCATGGGATTTGGAATGGGCAACTGCTGTCTTCAGGTGACATTCCAAGCTTGCAGCATTGAAGAGGCGAGGTACCTTTATGACCAACTAGCAACATTCTGCCCTATAATGATGGCTCTCAGTGCTGCTTCGCCGTTCTACAGAGGCTATGTGTCAGACATTGATTGTCGCTGGGGAGTTATTTCTGCCTCGGTAGATGACAGGACCGGGGAAGAGAGGGGGCTGGAGccttTGAAAACCAACAAATTTCGAATCTTGAAATCCAGATATGATTCAATCGACAGCTACCTCTCCAGCTGTGGCGATAGGTACAATGACATAGATCTGACAATAGACGAGGAGATCAACAAACAGCTGCTGGATGCAGGGATCGACAAACTGCTGGCCCAACACATAGCTCATCTCTTCATTCGGGATCCGCTCTCACTATTTGAAGAGAACATTTACTTGGATGATGAAAACGAGTCTGATCACTTTGAGAATCTGCAGTCAACCAACTGGCAGACAATGAGGTtcaaacctcctcctccaaactCGGACATCGGATGGCGGGTTGAGTTCCGTCCCATGGAGGTGCAACTTACCGATTTTGAAAACTCTGCATTCGTTGTTTTCATCGTCCTGCTCACCAGGGTTATACTGTCCTATAAACTGGACTTTCTCATCCCCTTGTCAAAGGTTGACGAAAACATGAAAGTTGCCCAGAAAAGAAATGCAGTCCAAGAGGGCATGTTTTACTTCCGGAAGGACATCTATAAAGGCTGCAACCCTGCCCTCGATAGCTCCTCATCGGCTGCCCAGAATGGCTTGGACAGTGAGGGTGACAATGAGTACACACTGATGAGCATTGACACAATCATCAATGGAAAGGAAGGAATTTTTCAAGGGTTGATACCAATCCTCAACTGCTACCTAGAAAACATGGAGGTGGATGTTGATACAAGATGCACCATCCTGAACTACCTGAAGCTCATCAAGAGACGTGCCTCCGGTGAACTGATGACCATGGCTAAATGGATGAGGGAGTTTGTGGACAAGCACCCCCAATACAAGCAAGACAGTGTCATAACTGACAGAATCAACTACGACCTACTCCGCAAGTGTGACAGCATCACAAAAGGAGAGGAGCGATGCCCAGAACTTATTGGTGACCCAGTCAATCGGGGCAAATGAACTTACTGTCACAGCTGTAATCAATTAATTAATGTGTTGTCCATCATTGATATTCATTAGCATGAAAAAGACCAAATATCTGTCTGGACAAAGTGGTCCAAACAAATTCAGTTTTAATGGAGAATATAGTGTGCATTGCGATGGTCAAGCGGGTGTATTgcatttgtatatacagtatcagaTTTGTACAATTCGAAAATTATTTTAATAAGTGAAATTCAATCGGATGTGTGATAGCAATTGGATATGTAATTTGATATCCTGTGTTCATGCTAACAAAGTCTGAGTGTGAAATTATGTAAATGCAGCAAACAAAGTTGTAGACTAGATTAATTTTAATCTTTAAGTCTACTGTAAATACTGAACTTTGATCTGCTCTACAAACATTTAACAAGGGTTATTTCATTTACGAATATGGTATATCTGCATTATCTGTCAAATGATTTGGCCTTTTAATGTGAGAAGTGTCAAATGAAAGTGTTTGATTTGCTGTGATATAGTAAAATCTTAAACTATTAAAGGAGTCTTGCATTGAAGTGAATGCGAACGTTTGAAAATAATGTTATGTCTCAATCAATAAATCTGTGTACAGCACTGACTAAGCATA

Function

symbol description
gsh1 Enables glutamate-cysteine ligase activity. Involved in glutathione biosynthetic process; response to cadmium ion; and response to hydrogen peroxide. Located in cytoplasm. Human ortholog(s) of this gene implicated in cystic fibrosis; glutamate-cysteine ligase deficiency; hemolytic anemia; and myocardial infarction. Orthologous to human GCLC (glutamate-cysteine ligase catalytic subunit).

NR:

description
glutamate--cysteine ligase catalytic subunit-like

GO:

id name namespace
GO:0006750 glutathione biosynthetic process biological_process
GO:0004357 glutamate-cysteine ligase activity molecular_function

KEGG:

id description
K11204 GCLC; glutamate--cysteine ligase catalytic subunit

RNA

RNA id representative length rna type GC content exon number start site end site
XM_021576493.2 True 3112 mRNA 0.44 16 34583316 34591320

Neighbor

gene id symbol gene type direction distance location
klhl31 LOC106589810 coding upstream 9436 34569055 ~ 34573880 (+)
LOC118942064 NA coding upstream 79650 34499031 ~ 34503666 (+)
hmgcll1 LOC106589805 coding upstream 203950 34347154 ~ 34379366 (+)
bmp5 LOC106589803 coding upstream 271166 34273867 ~ 34312150 (+)
col21a1 LOC106589801 coding upstream 311768 34225871 ~ 34271548 (+)
elovl5 LOC100192340 coding downstream 3637 34594957 ~ 34606103 (+)
LOC110499384 LOC106589811 coding downstream 24380 34615700 ~ 34626578 (+)
LOC110499387 gsta3 coding downstream 35899 34627219 ~ 34630262 (+)
LOC110499390 LOC106589817 coding downstream 64723 34656043 ~ 34671430 (+)
LOC110499597 NA coding downstream 93294 34684614 ~ 34685478 (+)
G1687735 NA non-coding upstream 164029 34414763 ~ 34419287 (+)
G1687732 NA non-coding upstream 171594 34411521 ~ 34411722 (+)
G1687731 NA non-coding upstream 171906 34411190 ~ 34411410 (+)
G1687730 NA non-coding upstream 172294 34410818 ~ 34411022 (+)
G1687845 NA non-coding downstream 35398 34626718 ~ 34683245 (+)
G1688405 NA non-coding downstream 151511 34742831 ~ 34743036 (+)
G1688410 NA non-coding downstream 155537 34746857 ~ 34747323 (+)
G1688414 NA non-coding downstream 158684 34750004 ~ 34750436 (+)
G1687675 NA other upstream 257062 34325837 ~ 34326254 (+)
LOC118942060 LOC106589768 other upstream 1398040 33177293 ~ 33196167 (+)
G1686317 LOC106589755 other upstream 1921668 32654354 ~ 32661648 (+)
LOC110499316 LOC106589729 other upstream 5006758 29572397 ~ 29588171 (+)
lhcgr lhr other upstream 5125395 29437357 ~ 29458499 (+)
LOC110499396 LOC106589821 other downstream 790389 35381609 ~ 35384567 (+)
G1689347 NA other downstream 1090047 35681367 ~ 35682437 (+)
LOC118942012 LOC106589797 other downstream 1109900 35701200 ~ 35702156 (+)
G1689671 NA other downstream 1290258 35881578 ~ 35881874 (+)
G1689732 LOC106612293 other downstream 1529296 36120616 ~ 36125390 (+)

Expression


Co-expression Network