XLOC_036825 (mib2)



Basic Information


Item Value
gene id XLOC_036825
gene name mib2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007119.7
NCBI id CM002892.2
chromosome length 54304671
location 53862745 ~ 53896982 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00071882
GACAGCGGGACTCGAACCAACTACCGCAGCGGGTACCAGGGAGCCTTCGACCTGCTGCTGTACGACAACGCTCAGATAGGGGTCCGCCACTCAAACATCATTTGTGACAGCTGTAAGAAGCACGGCATTATGGGAATGCGCTGGAAGTGTAAGGTGTGCTTCGACTATGACCTGTGCACTCAGTGTTACATGAACAACAAACACGACCTGACGCACGCCTTCGAGCGCTACGAGACTGCGCATTCACAACCGGTGAGTTTGACGCCGCGGCAGAATCTGTCCAGAATTATCCTGAAGGGAATCTTTCAGGGAGTAAAGGTGGTGCGGGGACCCGACTGGGACTGGGGGAACCAGGACGgtgagacagacacacacacacacacacacacacacacacacacacacacatatacaagcaAAAACTATAGAACAGTTtttgtaactgtcaatatggcaaatgaagccccgccttctaAAAGCTTAACCAATCAACTACACTGGAAAACAGATGTcctctggttttgtaatctgtatgaaaagaACGGAAGGTACAgtgAGCATGCGGAGCTGCAGCGGCAGGAGAGTGCAGACAGTCACTCGTTCCAGCAGGGTGATAAAGTCAAGTGTCTGCTGGAGGTGGATATACTGAGGCAGATGCAGGAGGGGCACGGAGGCTGGAACCCCAAGATGGCGGAGATTCGGGACGGTGCGCTGAATAACAGACCGAGGAGACGTGCGGGTCCAGTACAGCAATATCATCCGCTGGACATTTCACCCCGGTGCTCTGACCAAGGcaaggagaacacacacacacacacacacacacacacacacacacacacaccagtcttatctggctcaggtgtgtttaattggagtcGGAGCTGAGCTCTTGgctctAGGGCAGGTGGGTAAGGTGTTGAAGGTGTATGCTGACGGTGATCTGCGAGTGGCGTTCGGAGGACAGACGTGGACCTTTAACCCGGCGTGTCTCTCCGCTCAGCCTGGGGAAGTGGACGCAAACCTGATGACGGTGGAGAACGCCAGCGAATCCAGCaGTACAGTGATCTCGGTGCTGGAGAAGCTGTTGTCCCAGTCTACAGAGCAGGATAACCCGGGCCGGCTGGTCATCGAAGCGGCTCACGGTAGCGCTGCCAAAGTTCGTGAGCTGCTGCAGAAACACCCCGACAAAgtggaCATTAAGAACCAGGGAAAGACGGCTCTGCAGGTCGCAGCTCATCAGGGTCATGTAGAGGTGGTGAAGGTCCTGCTACAGGCTAACAGTAGCATTGAAGCTAAAGATGAGGACGGAGACGCGGCGCTGCACTACACGGCCTTCGGtattgcagacagccgtgtaataacactgaataaagcacattatCAGCATCTGAAAGGATTGTGCTCGCTTCACATGGCAGAAAATAGAACAGAACACATTGTCTTtcagtgtgtacatgtgtgtgtttgtgttgtgtgtgtgcaggacTCATACGGCGACACACCTTTACACGACGCCATCGCTAAAGACTTCAGGAGCATCATTGAGATCCTGACGGTGGTTCCAAACATCGATTTCACTCAGCAGAACAACCGCGGCTTCAACCTGCTGCACCACGCCGCTCTGAAGGGCAACaaactAGCGACAGAGATGATTCTTTCTCGAGCTCGACAGCTGGCGGATGTGAAGAAGGAGGACGGTTTCTCTGCGCTTCATCTGGCTGCGCTCAACAACCATCGCGACGTAGCCGAGATTCTCCTCAAAGAGGGTCGCTGTGACATCAACATCCGCAACAACCGCAACCAGACGCCGCTGCAGCTAGCCGTTACGCAGGGCCACATGGCGCTCGTAGCGCTGCTAGTGATGGAGGGAGCAGACGTGAACGCAGAGGACGAGGATGGAGACACAGCCATGCACACTTCCCTCAGTAGACAGCAGCTGACCACCGTCATCAGCAGCGCAGAGGGAGACGGAGCCGTGCTGTACGGCAGGTTGTGCAGTTCGGGGCTGATGGGAAACACTGAGCTGAATGTAGGAGCTGCCATCGCATGTTTCCTGGCGCAGGAGGGAGCCGATATCAGCTACGCTAACCATAAAGGCAAGAGCCCACTGGACCTGGTGACGGACAGCAGCGTGCAGACCCTCATCAGGAGCTTTGCGGAGAAACACAGgctcCATGCCGTGTCGTGTGGCACCggcagtagcagcagcagcagcagtctcAGGCGTGTTCACACCACACCCAACACTATGACCAACCTGGCGGTGCCCAGTGTGACGGGGCCCAGCGAGTGCCTGATCTGCTCGGAGCTCGCTCTGCTGGTGCTCTTCTCACCGTGCCAACACAGCGTCGCATGTGAagaatgTGCTCACAGAATGAAGAAGTGTATCCGCTGCCAGGTCACAATAACAAAGAAAATTCGACAAGATCAGACGGAGGTGGAGTGCAGCCCGAGCTCGGAGAACTCAGAACAGCACCACCTGCTGGAGCAGCTGCAGTCGCGCTACAGACAGATGGAGGAGCGCATCACCTGCCCCATCTGCATAGACAACCATATACGGCTGGTGTTCCAGTGTGGCCACGCCTCCTGCATCGactgtagctccgccctcaaGACCTGCCCCATCTGCAGACAGACCATCCGCGAGAGGATACAGCTCTTCGTCTGA

Function


symbol description
mib2 Enables identical protein binding activity. Contributes to ubiquitin-protein transferase activity. Acts upstream of or within several processes, including melanocyte differentiation; protein autoubiquitination; and regulation of receptor internalization. Located in cytoplasmic vesicle and perinuclear region of cytoplasm. Is expressed in inner ear; mesenchyme pectoral fin; and pectoral fin. Orthologous to human MIB2 (MIB E3 ubiquitin protein ligase 2).

GO:

id name namespace
GO:0002090 regulation of receptor internalization biological_process
GO:0016567 protein ubiquitination biological_process
GO:0051865 protein autoubiquitination biological_process
GO:0031398 positive regulation of protein ubiquitination biological_process
GO:0030318 melanocyte differentiation biological_process
GO:0048471 perinuclear region of cytoplasm cellular_component
GO:0000151 ubiquitin ligase complex cellular_component
GO:0031410 cytoplasmic vesicle cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005515 protein binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0004842 ubiquitin-protein transferase activity molecular_function
GO:0042802 identical protein binding molecular_function
GO:0008270 zinc ion binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-050628-1 Enables identical protein binding activity. Contributes to ubiquitin-protein transferase activity. Acts upstream of or within several processes, including melanocyte differentiation; protein autoubiquitination; and regulation of receptor internalization. Located in cytoplasmic vesicle and perinuclear region of cytoplasm. Is expressed in inner ear; mesenchyme pectoral fin; and pectoral fin. Orthologous to human MIB2 (MIB E3 ubiquitin protein ligase 2).

Ensembl:

ensembl_id ENSDARG00000103609

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00071882 True 2671 mRNA 0.55 17 53862745 53896982

Neighbor


gene id symbol gene type direction distance location
XLOC_036824 CABZ01090219.1 coding downstream 11160 53841302 ~ 53851585 (-)
XLOC_036823 BSN coding downstream 59316 53794022 ~ 53803429 (-)
XLOC_036822 NA coding downstream 80893 53781481 ~ 53781852 (-)
XLOC_036821 apeh coding downstream 89206 53747925 ~ 53773539 (-)
XLOC_036820 tlr9 coding downstream 127346 53730368 ~ 53735399 (-)
XLOC_036826 ubiad1 coding upstream 21252 53918234 ~ 53926228 (-)
XLOC_036827 cdk11b coding upstream 51212 53948194 ~ 53960349 (-)
XLOC_036828 SLC35E2B coding upstream 82266 53979248 ~ 53991184 (-)
XLOC_036829 NA coding upstream 164715 54061697 ~ 54068296 (-)
XLOC_036830 NA coding upstream 173179 54070161 ~ 54075099 (-)
XLOC_036813 NA non-coding downstream 395042 53464218 ~ 53467703 (-)
XLOC_036812 CU914536.1 non-coding downstream 505849 53356779 ~ 53356896 (-)
XLOC_036807 NA non-coding downstream 927275 52933059 ~ 52935470 (-)
XLOC_036832 NA non-coding upstream 215047 54112029 ~ 54113768 (-)
XLOC_036833 NA non-coding upstream 270071 54167053 ~ 54168171 (-)

Expression



Co-expression Network


Homologous


species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000050_00851621_00899726 MIB2 coding CI01000050 null 851526 ~ 901164 (+)
bowfin (Amia calva) AMCG00002251 mib2 coding CM030136.1 CM030136.1 8957110 ~ 8982144 (-)