XLOC_037001 (bmpr2b)


Basic Information

Item Value
gene id XLOC_037001
gene name bmpr2b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007120.7
NCBI id CM002893.2
chromosome length 56459846
location 12959760 ~ 13111163 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00072834
GGAGCTGAAGTTACCGAGAGCGGCCGCGGGAGCTCGACACGATCCGCGGGGCGATAATCAACCACAACGGGGAGAAAAGCGCTTATTTAACCGAACAGACCCTGACCGACCGGCAATCAGTTTAACGACCATCACACAGTCTACCGACAGTCGCCGCGTTGTTCATTACAGGCCTCCGTCGCTTTGGATCGGACTCAATGTCGCTCCTGTTCGGCCGCTTGAGCTCGACGCCTTCTGCCGCAGGTTTACTTCATTTCAGAGACATCATTTAAGGGATAATGCAGGAATAAAACCGGGCACAGTCGGGAAATGTCGGACATGTCGTCAGCTCGTGAAGCTAAACATCGACTGAAGCGGACTGACACCAAGAAACCTGACCCATATTGAGATCCTGAGCTCGAGCATCTGGACCAGAACCAAATATTACATCGAAACTAAATCTTGTTTATAAACACAGACGACAACCGAGAGACGCCACACAGCAGGTTTTGAGacctttagttttattttaagataTGCGAGGAAGTGTATTATACATATTAAATGAAGTATAATCGCTCAAACTCCCAACCAGCATGGAGAAAATGCGTTTATAAGCTGTTTATCGAAACCAAAGGCATCTAAAATCATGCGCTGCCTCCAAATCTTCATCTGCACTAACGTTAGTCATTTCGGATTGTTTGCTCCGTGCACATGAGCTTGAACTTCGGTCGATAGAAAGAAGAAAGGGGGAACAGAAAATCTAGTTACTGGAACTTTTTTTTGGAGCTGAATCCATCCAGAAGCGGCAGCAGGATGAGAGTGCGGATCCTAAACCGGACATCAGTACTGTCACTCGGGCTCTGCTCACTGCTTCTGCTCAGTGCTGTGGCCGCTGCTCAGAGTGAAGAGCGCGAGCGGGAGTGTGCTTTTAATGACCAGCACCAGCAGGTGGATGAGCAGAGTGTGGCAGGTGACTGGCACATCACCAGAGAAAATAACACCATCCTGTGCAGCAAGAGCAGCCGCTGCTACGGCCTCTGGGAGAAAACACATGACGGAGAGATCCGTCTGGTCAAACAAGGCTGTTGGACTTACATTGGTGACCAGCAGGACTGCCATGACGACCGTTGCGTGGTTACCACAACGCCATCGCAGATCCAGAATGGCACCTACAGATTCTGCTGCTGCAGCACCAACATGTGCAACGTCAACTTCACAGAGAACTGGGTGCCCAGTCCCACCAGCACTGCCAACCGTGATCAGCCGCCTATACACAGAGATGAGGCCATCTTCATCGCCCTGGCCTCCGTCTCCATTGTGGCCGTCCTTATTGTCGCGCTGTTCTTTGGCTATCGTGTGATGATGGGcgagtgtaaacagggcctgcaCAATATGGACATGATAGAGGCTGCGCCATCTGAACCTTCGCTGGATTTAGACAGTTTAAAGCTCCTCGAACTGATTGGCCGAGGCCGCTACGGTTCCGTCTACAAGGGGTCTCTTGACGAACGGCCGGTTGCAGTAAAAGTTTTTACCTATGCCAACCGGCAGAACTTTGTGAATGAGCGCTCCATCTACCGAGTGCCTCTTCTGGAGCATGAAAACATTGCTCGCTTTATCGTCGGCGATGAGCGGATGACCACTGACGGACGCATGGAGTACCTGCTGGTCATGGAGTACTACCCTCATggcTCGCTGTGCCGCTATCTGAGTCTGCACACGCTGGACTGGGTGAGCTGCTGTCGTCTGGCTCATTCACTGACCAGAGGACTGGCCTATCTGCACACTGAGCTCCTGAGAGGAGATATATACAAACCTGCCATTTCGCACCGGGATCTAAACAGCCGGAATGTTCTAGTGAAGAACGATGGCACCTGTGTGATCAGCGACTTCGGTCTGTCTATGAAGCTGACTGGAAATCGTCTGGTACGGCCTGGAGAAGAGGAAAACGCCGCCATCAGTGAGGTGGGCACGATCCGCTACATGGCGCCGGAGGTGCTGGAGGGAGCCGTGAACCTCAGGGACTGCGAGTCTGCATTGAAACAGGTGGACATGTACGCCATCGGCCTCATCTACTGGGAGACCTTTATGAGGTGCACTGACCTTTTTCCAGGAGAGACAGTGCCAGAATACCAGATGGCTTTCCAGGCCGAGGCGGGAAACCACCCGTCCTTTGAGGACATGCAGGTGTTGGTGTCCAGAGAGAAACAGAGACCCAAGTTCCCAGAAGCCTGGAAGGAGAACAGCCTGGCTGTGCGCTCTCTAAAGGAGACTATGGAGGATTGCTGGGATCAGGATGCAGAGGCTCGTCTGACAGCGCAGTGTGCAGAGGAGCGTATGGCAGAACTGCTGCTGATTTGGGAAAGGAACAAACCTGTCAGTCCCACCATCAATCCCATGAGCACAGCGCTGCAGAACGAGAGGAATCTGACCCACAGCCGCAGGGCTCCCAAAATGGGCTCTTACCCAGATTACTCTTCATCCTCTTACATCGAGGATCATGAGGGCATGGTGAAGAACCTCCCAGGCGACGTCTCCACGTCTGGCACTTCCTCTGTGGGTGGTGTGGGCGTGAGTGGCAGCAGTGGGGGCGTTGCAGCGACCGGAGAGAAGAACAGAAACTCCATCAACTATGAAAGACAGCAAGCTCAGGCGCAAGCTCGACTGCCCAGTCCTGAAACCAGCGGCACAAGTTTGTCCACCACAACCACCACAACAGGCCTCACACCCAGTACCATCATGACCACCATCTCCGAATCGGGCCACTCGGAGGACACAGGAGCCGGAGGAAGTGTACCAGTGTGCCTTCAACTCACAGAGGAAGATCTGGAGACCACCAAACTGGACCCCAAAGAGGTGGACAAGAACCTGAAAGAAAGTTCTGATGAGAATCTGATGGAGCACTCGCAGAAACAGTTCAGCGCCCCTGATCCACTCAGCTCGGGCAGCACCAGTCTTTTATACCCACTGATTAAACTCGCAGCAGAAGTGACTGGAGGATCTGGAAGTGGTGGACAAACTGATTTCGGGGTGGGCAGCAGTGGAATGAGCGACACTCCCACAGCCATGTTTCCTCTCCCCAAACAGCAGAATCTCCCCAAGAGGCCCACTAGCTTACCCCTCAACACCAAAAATCCTGGTAGGGAGTCTTCGTCGTCTCGATTGAAATTCGGGAAGCACAAGTCCAACCTGAAGCAGGTGGAGACAGGTGTAGCCAAGATGAACACTGTGGTGGCCGTCGAGCCACACTTGGCCACCGTCACCAACAATGGACCCAGTGTGCGCAGTGGTGCTGGAGTGGTCGTAGTAAATGGATATGGAGTGGGCAATGGTGCCAGCTCCTCTGATGCGTTTGGAAACACGAACCCCGTCGGGCCACAGGGTGAAGGGGGCGCTCCTCTGCTGCAGAGCCAACTGAGCGGAGAAGACAGCCGACTCAACATCAACATCAACTCCAGCCCTGATGAACACGAGCCCCTGCTAAGAAGAGAGCAGCCGGCCGCGCGGGATCACTCCGGTCGCACCaactccaacaacaacaacagcaacattcACACCACTGCCACGGTTTGTGCGCTCACCGCTGCAGACGCCCAGATAGAGGCTTTAACCTGCCTGTCGGGAGCGCCAGACGGAAGGGATAATGGGGTTCCATTGAGGCCACCTAAACCCAGAAGACCAGAGCGGCCAAACTCACTGGACCTGTCAGCCTCTTCCCAGAATTCTTCTCTTTTAGATGAGGCCGTGTCGCAGGAGGGAAAGGCCGGATCAGCTGAGAAGATTAAAAAACGTGTGAAGACTCCTTATTCGTTGAAAAGATGGCGTCCTTCCACATGGGTCGTCTCCACTGATACACTAGATGGAGAGGTGAACAACAACGGGCACAGCCAGCAGACGATGATGGCAGTAAGTGGAGGTGGTCACCCAAGCGCTGGCCAATCAAAGTCCAGCATCGCCGTGTTTTTGGTCGGCGGAGGAACAGCAACAGCTACTCTGACCTCCGATCCTCCAGATATGACCTGCCTGTGAACTCGCATGAGGATGAGCT
>TCONS_00072835
GcgagtgtaaacagggcctgcaCAATATGGACATGATAGAGGCTGCGCCATCTGAACCTTCGCTGGATTTAGACAGTTTAAAGCTCCTCGAACTGATTGGCCGAGGCCGCTACGGTTCCGTCTACAAGGGGTCTCTTGACGAACGGCCGGTTGCAGTAAAAGTTTTTACCTATGCCAACCGGCAGAACTTTGTGAATGAGCGCTCCATCTACCGAGTGCCTCTTCTGGAGCATGAAAACATTGCTCGCTTTATCGTCGGCGATGAGCGGATGACCACTGACGGACGCATGGAGTACCTGCTGGTCATGGAGTACTACCCTCATggcTCGCTGTGCCGCTATCTGAGTCTGCACACGCTGGACTGGGTGAGCTGCTGTCGTCTGGCTCATTCACTGACCAGAGGACTGGCCTATCTGCACACTGAGCTCCTGAGAGGAGGTGAGGCCCACACACGTCATTTACACCTCCTACTGCATACTGTATTTACAGGAAAAGTTGAACTGTTTGCATTATCAAGAGAAACAAGCAAGCTGGCATTGAGTATGCCACTTACTCATTACTTATTATTATCCCCAAAATATTGagatattg

Function

symbol description
bmpr2b Enables transforming growth factor beta-activated receptor activity. Acts upstream of or within BMP signaling pathway; embryonic organ morphogenesis; and vasculature development. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Is expressed in several structures, including blood island; cardiovascular system; gonad; gut; and posterior pronephric duct. Human ortholog(s) of this gene implicated in heart septal defect; primary pulmonary hypertension; pulmonary hypertension; and pulmonary venoocclusive disease. Orthologous to human BMPR2 (bone morphogenetic protein receptor type 2).

GO:

id name namespace
GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway biological_process
GO:0002040 sprouting angiogenesis biological_process
GO:0003146 heart jogging biological_process
GO:0071363 cellular response to growth factor stimulus biological_process
GO:0048570 notochord morphogenesis biological_process
GO:0030509 BMP signaling pathway biological_process
GO:0006468 protein phosphorylation biological_process
GO:0007368 determination of left/right symmetry biological_process
GO:0016310 phosphorylation biological_process
GO:0001944 vasculature development biological_process
GO:0001945 lymph vessel development biological_process
GO:0001947 heart looping biological_process
GO:0005886 plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0043235 receptor complex cellular_component
GO:0016740 transferase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function
GO:0004675 transmembrane receptor protein serine/threonine kinase activity molecular_function
GO:0016301 kinase activity molecular_function
GO:0005024 transforming growth factor beta-activated receptor activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-070618-2 Enables transforming growth factor beta-activated receptor activity. Acts upstream of or within BMP signaling pathway; embryonic organ morphogenesis; and vasculature development. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Is expressed in several structures, including blood island; cardiovascular system; gonad; gut; and posterior pronephric duct. Human ortholog(s) of this gene implicated in heart septal defect; primary pulmonary hypertension; pulmonary hypertension; and pulmonary venoocclusive disease. Orthologous to human BMPR2 (bone morphogenetic protein receptor type 2).

Ensembl:

ensembl_id ENSDARG00000020057

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00072834 False 4030 mRNA 0.53 13 12959760 13111163
TCONS_00072835 True 591 lncRNA 0.50 3 13076852 13089863

Neighbor

gene id symbol gene type direction distance location
XLOC_037000 si:dkey-230p4.1 coding upstream 5936 12905591 ~ 12953824 (+)
XLOC_036999 hce2l1 coding upstream 56193 12894578 ~ 12903567 (+)
XLOC_036998 hce2l2 coding upstream 65669 12887491 ~ 12894091 (+)
XLOC_036997 glb1l coding upstream 90711 12847040 ~ 12869049 (+)
XLOC_036996 CR752651.1 coding upstream 131640 12828005 ~ 12828120 (+)
XLOC_037002 fam117bb coding downstream 9256 13120419 ~ 13212790 (+)
XLOC_037003 carf coding downstream 118422 13229585 ~ 13251327 (+)
XLOC_037004 CR407547.1 coding downstream 337366 13448529 ~ 13448648 (+)
XLOC_037005 NA coding downstream 357911 13469074 ~ 13471527 (+)
XLOC_037006 als2a coding downstream 517472 13628635 ~ 13672200 (+)
XLOC_036995 NA non-coding upstream 490717 12461619 ~ 12469043 (+)
XLOC_036991 CR847976.1 non-coding upstream 1511851 11447777 ~ 11447909 (+)
XLOC_036987 NA non-coding upstream 2021291 10936773 ~ 10938469 (+)
XLOC_036985 NA non-coding upstream 2199647 10737086 ~ 10760113 (+)
XLOC_037014 NA non-coding downstream 1001312 14112475 ~ 14117000 (+)
XLOC_037015 AL929266.1 non-coding downstream 1031910 14143073 ~ 14147153 (+)
XLOC_037016 NA non-coding downstream 1041005 14152168 ~ 14197503 (+)

Expression


Co-expression Network