XLOC_037041 (tnfsf11)



Basic Information


Item Value
gene id XLOC_037041
gene name tnfsf11
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007120.7
NCBI id CM002893.2
chromosome length 56459846
location 18023288 ~ 18043298 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00072904
GAAAAAGCGAGATCATCCGTGTCTATTATCTGATTGGCTGTCTTCGAAGCAAGTTACATTGCCCACCCACATGTTTATATGAGTCGTTGATCATTTGTTGAATCCTCCCACTGAGAGACAGGATCTGTGCCGCGATCGGGCGTTCATGGCAGCTAATGATTATCGCGCTTACCTGCGGAATCATATCGATATGGAAGAGGCTCCGGCGCGCGCTCCACACACGGGCTCCACGCACAGAGCGCTCATTTTCGGCACGCTCGCTGTCATGGCACTGCTGCAGGTCGCGTCTAGTGTGGCGATTCTGTTGCACTTAACCGGTTATCTCCGAGAGGTCGATCTTGCCTCACCACAGCAGAGTCCTAATGAGGAAATGCACAGTGAAACTTTAATAGGCGATCAAATGAATAGTTCAACAaaggacaaaacaaaaaaagtgccATCAGCTCACCTTCCAATCAAGACGCCCATAGACTTATTACCCAATGAAAACGGTTTAACCCAGATAGCCTGGGATGGCATGAAAGCAGAGAATCTGAAGAGGATGAAATATAAAGATAACCGAATTATAGTGGATTCCCCTGGATACTACTATGTATACGCCAAGACCTGTTTTCGATACCATGAGATTCACAGCTCTGAGAAAGTGAACATCAGCAACATAGAGCTGGGTCAGTACATTTACCACGAAAAACACTCACGGTCTGAACCTCCTACTGTCCTTGCAAAAAGCAGCGGGACGCCGGAGTGGAACATTAAAAAGTATAACAAGTACTGCATGGAGCAGGGCAGAGGTGTCCGGCTGGAGAAAGACGATAGAATTTACGTCAAAGTATCCAACGCACAACTGCTGGACCCGGCAGTTGAAGAGACgtattttggttgttttaaaataagtaaatgactTTGACATTTTTTGCTACTGAAACGTTTGTGCACATTTTTTTTCATCCATACAAACTTTTTCAAAGTGACCATGAACCACTGAGCACTTGTTTTGAATCACTGACTTTTGGATTTTGTTCAATATTGATGACGTTTAAGAGCACATTATGATTTCCTAATCATGCCATCGAAGCTCTTAAGTACCAGCACTAGAAGATTTAGAATGGACTCAGGCctcatttgtgtgtttttaaggccAATACTGGCAAAAGTATTCTCAAAAAGACTGTTGGGAATCAAAACGGTGGAGTGTTTTTGGACAGTCTCAGCAAAGTTTGCCAAATTGCAGGAGTCTCAAACAACAGAGGAAACTGTACAAACTAAATGACCAAATTTGGTTGGAAATGTAATAGGATCAATATAAAAGCAATGTCGCATTTGCTGCAAAATAGTGCCCTTAAGACTGGCTAACACTGTGCACATTTTAATGATCTTATAAGGTTGTAGCTTGTGCAAACAGTTGAAAATCAATACGTGCCAAACACAGACACTTGCATAACTCAGGTGTAGTTGGATGTCATCAATCCATTACAAGCTCAATAACCTGCgctcttagggtgcttttacgCCTGTGAATTGATTtagttgttccaaaacagggattaa

Function


symbol description
tnfsf11 Predicted to enable tumor necrosis factor receptor binding activity. Acts upstream of or within response to mechanical stimulus. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in head and scale. Human ortholog(s) of this gene implicated in autosomal recessive osteopetrosis 2 and osteoporosis. Orthologous to human TNFSF11 (TNF superfamily member 11).

GO:

id name namespace
GO:0006955 immune response biological_process
GO:0009612 response to mechanical stimulus biological_process
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0005164 tumor necrosis factor receptor binding molecular_function

KEGG:

id description
ko04064 NF-kappa B signaling pathway
ko04060 Cytokine-cytokine receptor interaction
ko04917 Prolactin signaling pathway
ko04928 Parathyroid hormone synthesis, secretion and action
ko04380 Osteoclast differentiation
ko05207 Chemical carcinogenesis - receptor activation
ko05224 Breast cancer
ko05323 Rheumatoid arthritis
ko04052 Cytokines and growth factors
ko04090 CD molecules

ZFIN:

id description
ZDB-GENE-090805-2 Predicted to enable tumor necrosis factor receptor binding activity. Acts upstream of or within response to mechanical stimulus. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in head and scale. Human ortholog(s) of this gene implicated in autosomal recessive osteopetrosis 2 and osteoporosis. Orthologous to human TNFSF11 (TNF superfamily member 11).

Ensembl:

ensembl_id ENSDARG00000068141

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00072904 True 1548 mRNA 0.43 4 18023288 18043298

Neighbor


gene id symbol gene type direction distance location
XLOC_037040 akap11 coding upstream 16656 17971935 ~ 18006632 (+)
XLOC_037039 dgkh coding upstream 62947 17787864 ~ 17960341 (+)
XLOC_037038 AL929161.1 coding upstream 360223 17662950 ~ 17663065 (+)
XLOC_037037 NA coding upstream 386614 17636381 ~ 17636674 (+)
XLOC_037036 rgcc coding upstream 573416 17438765 ~ 17449872 (+)
XLOC_037042 BX248332.1 coding downstream 120331 18163629 ~ 18164027 (+)
XLOC_037043 dnajc15 coding downstream 172642 18215940 ~ 18278580 (+)
XLOC_037044 BX004817.1 coding downstream 273105 18316403 ~ 18316520 (+)
XLOC_037045 BX004817.2 coding downstream 307069 18350367 ~ 18350483 (+)
XLOC_037046 lacc1 coding downstream 529672 18572970 ~ 18587754 (+)
XLOC_037032 NA non-coding upstream 679744 17337151 ~ 17343544 (+)
XLOC_037030 NA non-coding upstream 795994 17226244 ~ 17227294 (+)
XLOC_037028 NA non-coding upstream 1246673 16775987 ~ 16776615 (+)
XLOC_037047 BX957328.1 non-coding downstream 562162 18605460 ~ 18608269 (+)
XLOC_037050 NA non-coding downstream 868399 18911697 ~ 18914987 (+)

Expression



Co-expression Network


Homologous


species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000080_03858298_03868014 TNFSF11 coding CI01000080 null 3857803 ~ 3868279 (-)