XLOC_037337 (cyp27a7)



Basic Information


Item Value
gene id XLOC_037337
gene name cyp27a7
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007120.7
NCBI id CM002893.2
chromosome length 56459846
location 38408991 ~ 38419140 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00073461
ACTGTTCGCCCTGCCTTCATAatggctgtttgttttgctttgagcTCTGCAGAAAGGCTCGGAATCGGATTGGGTTTTCTGAGACCCACGGCAGCGGCCACAGGCTTCAGGAGAGCAGCAGGAAATGCTGCGGCTGCTTCTGTCAGTGTCCAGGACGGCCACAGAAAGCTGAAGACTGAGGCTGACCTTCCAGAGATCAAAATCTTTACCATGTTGTACAGACTGCTCTTTAAAGGCTACCTGAGTCGCATGCATGAGCTACAGTTATATGAAAAACAGCTTTATGGCCCTTTGTACAAAATCAATGTCGGAAACTTCCAATCCGTTGCATTAAACAGTGTGGACTTACTGGAGGAACTCCTTCGAAAAGATGAGAAGTTTCCTTCCAGGGGAGACATGACTCTGTGGACAGAATATCGGGACATGAAAGGCATCGGCTACGGCCCTTTCACAGAAGAAGGAGAGAAATGGTACAAACTGCGAGCGGTGCTGAATAAACGCATGCTGCATCCAAAGGACTCGGTTCAGTATGGAGATGTGGTGAATGCAGTGATCACAGACTTCATCAAACGCATTTACTATCTGCGGGAGATGAGTCCTACAGGGGATCTGGTCTCTAATCTGACCAATGAGCTTTACCGATTCTCTCTTGAAGGAATCTCCTCCATTCTGTTTGAGACACGCATTGGCTGCCTGGAGAAAGAGATTCCTGCTGAGACGCAACATTTCATTAATTCTATTGCACAGATGCTCACCTACAGCATGCCCGTGGTGTTTATGCCCAACTGGACCCGCAATTACTTGCCATTCTGGCAAAGGTACATTGGCGGCTGGGATGGCATATTCAAGTTCGCTGGAAAAATGATTGACATGAAGATGGAGGCCCTTCAGAAGCGTGTAGATGCAAATCAGGAGGTTGCTGGAGAATATCTCACATATCTGCTTTCTAATGGCAAGATGAGCAGCAAAGATGTTTATGGAAGTGTATCTGAGCTGCTGCTGGCTGGCGTCGACACAACCTCCAACACTATGTTGTTTGCACTGTATCACCTCTCAAAAGACCCAGAAACTCAAGACATTTTGTATCAGGAGGTAACCAACGTCTTAAAGGATGACAGAATCCCAACCGCACAAGAAGTGAACACCATGTCCTACCTCAAAGCTGTCATCAAGGAAACTTTAAGGTTGTATCCTGTGGTGCCAATGAATGCTCGGCTTATTGCAGAAAATGAAGTTGTCATTGGTGGACACTTATTCCCTAAAAATACAACTTTCACTCTGTGCCACTACGCAATCAGTCGTGATGAAAAAGTCTTCCCAGAACCACAGAAGTTTAAACCTGAGCGCTGGCTGCGAGACGGCAGAACCAGACCAAACCCATTTGGATCGATCCCATTTGGATTTGGAGTCAGAGGCTGTGTCGGTCGTCGCATTGCTGAATTGGAAATGTACCTGGCATTGGCAAGGCTAATCAAGTTGTTTGAAATTAGACCAGACCCGACTGTAGGTGAGGTGAGGTCACTGAATCGTACAGTGCTTGCTCCAGACAGAAAAGTTAATCTGCACTTTGTGGAAAGAAAGAAGACTGAAGCATAGCTAAAGAAGACATTATGTTTCAACAAGCTGCATGTACATTTGAAAAGCAACCTGCAAAAGTGAATTATGTAAATGTCACGTAATGGTTACTCTTACAAAAATTATCCTTGGTtttattatacactgtaaaacccaacacttaattttatcaaataaaatgagtgtagttaactcaaaattgactgaaagttaatactacttgtttgaaaagagttttgaactcagtgttgaaagtaatgagtttattaaatacctcatcacttcaacttaaatggagtaagttcgcagtactcattaggattagtttttgaacttaaatggtttgttgcaatcggtttcctcaaatggtttgagttacctttacttttggggttttacagtgtagtaaacaaGCTGTAACCatgttcttcttattattatttttattattattattatttgtattgacGTATGTATAACAACAATTTAACTACAAATACCATGGGAAATTAGTAGTCACCATGGTTTTAACATCAAAAACCATATTtttgtagtattagtattagtaatgaaaccatggttaattttcaTAAGGGTACCAATGTCTGATTATGATTGtgttgtgctttgaaatatgcaataTGGAGGACcatgtatatattacactgtgaaaagctcTTTTTTCCCTCATGCagatttaagatttattttaaatggttgctGTGCATTTTATTCCATTGTGCAATAATGTAGCCTATTTTATAGAGCTAACAATCAATTAAACTTTTTAATGAATCCA
>TCONS_00073462
GCTGAATTCatgtatgtgttttgtttttgtcatgacagttaTTGCGCATACTAATTCATCACCAATATTTAACATGTACTCCATTTGCAACCATTTCCTCCACAGGAATCTCCTCCATTCTGTTTGAGACACGCATTGGCTGCCTGGAGAAAGAGATTCCTGCTGAGACGCAACATTTCATTAATTCTATTGCACAGATGCTCACCTACAGCATGCCCGTGGTGTTTATGCCCAACTGGACCCGCAATTACTTGCCATTCTGGCAAAGGTACATTGGCGGCTGGGATGGCATATTCAAGTTCGCTGGAAAAATGATTGACATGAAGATGGAGGCCCTTCAGAAGCGTGTAGATGCAAATCAGGAGGTTGCTGGAGAATATCTCACATATCTGCTTTCTAATGGCAAGATGAGCAGCAAAGATGTTTATGGAAGTGTATCTGAGCTGCTGCTGGCTGGCGTCGACACAACCTCCAACACTATGTTGTTTGCACTGTATCACCTCTCAAAAGACCCAGAAACTCAAGACATTTTGTATCAGGAGGTAACCAACGTCTTAAAGGATGACAGAATCCCAACCGCACAAGAAGTGAACACCATGTCCTACCTCAAAGCTGTCATCAAGGAAACTTTAAGGTTGTATCCTGTGGTGCCAATGAATGCTCGGCTTATTGCAGAAAATGAAGTTGTCATTGGTGGACACTTATTCCCTAAAAATACAACTTTCACTCTGTGCCACTACGCAATCAGTCGTGATGAAAAAGTCTTCCCAGAACCACAGAAGTTTAAACCTGAGCGCTGGCTGCGAGACGGCAGAACCAGACCAAACCCATTTGGATCGATCCCATTTGGATTTGGAGTCAGAGGCTGTGTCGGTCGTCGC

Function


symbol description
cyp27a7 Predicted to enable cholesterol 26-hydroxylase activity and vitamin D3 25-hydroxylase activity. Predicted to be involved in calcitriol biosynthetic process from calciol and cholesterol metabolic process. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in cerebrotendinous xanthomatosis. Orthologous to human CYP27A1 (cytochrome P450 family 27 subfamily A member 1).

GO:

id name namespace
GO:0008203 cholesterol metabolic process biological_process
GO:0036378 calcitriol biosynthetic process from calciol biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0005739 mitochondrion cellular_component
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen molecular_function
GO:0004497 monooxygenase activity molecular_function
GO:0005506 iron ion binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0016491 oxidoreductase activity molecular_function
GO:0031073 cholesterol 26-hydroxylase activity molecular_function
GO:0020037 heme binding molecular_function
GO:0030343 vitamin D3 25-hydroxylase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-081104-519 Predicted to enable cholesterol 26-hydroxylase activity and vitamin D3 25-hydroxylase activity. Predicted to be involved in calcitriol biosynthetic process from calciol and cholesterol metabolic process. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in cerebrotendinous xanthomatosis. Orthologous to human CYP27A1 (cytochrome P450 family 27 subfamily A member 1).

Ensembl:

ensembl_id ENSDARG00000033802

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00073461 False 2374 mRNA 0.41 9 38408991 38419140
TCONS_00073462 True 881 lncRNA 0.45 5 38412748 38418111

Neighbor


gene id symbol gene type direction distance location
XLOC_037336 bcs1l coding upstream 1815 38399912 ~ 38407176 (+)
XLOC_037335 plcd4b coding upstream 18001 38369872 ~ 38390990 (+)
XLOC_037334 ddx18 coding upstream 56771 38314466 ~ 38352220 (+)
XLOC_037333 tfcp2l1 coding upstream 97241 38292919 ~ 38311750 (+)
XLOC_037332 clasp1a coding upstream 117182 38163876 ~ 38291809 (+)
XLOC_037338 cyp27a1.2 coding downstream 872 38420012 ~ 38425491 (+)
XLOC_037339 CYP27A1 coding downstream 8432 38427572 ~ 38433916 (+)
XLOC_037340 cyp27a1.4 coding downstream 27364 38446504 ~ 38457413 (+)
XLOC_037341 mcm3ap coding downstream 38666 38457806 ~ 38500391 (+)
XLOC_037342 lmln coding downstream 83384 38502524 ~ 38516727 (+)
XLOC_037331 BX548038.2 non-coding upstream 247602 38161263 ~ 38161389 (+)
XLOC_037330 BX548038.1 non-coding upstream 248419 38160446 ~ 38160572 (+)
XLOC_037326 NA non-coding upstream 384930 38021890 ~ 38024061 (+)
XLOC_037325 CU896658.1 non-coding upstream 531441 37877434 ~ 37877550 (+)
XLOC_037322 NA non-coding upstream 900718 37506959 ~ 37508273 (+)
XLOC_037349 CR376853.1 non-coding downstream 367788 38786928 ~ 38787044 (+)
XLOC_037351 CR812481.1 non-coding downstream 591292 39010432 ~ 39014598 (+)
XLOC_037353 NA non-coding downstream 1444113 39863253 ~ 39865672 (+)
XLOC_037354 BX255912.2 non-coding downstream 1718357 40137497 ~ 40137612 (+)
XLOC_037355 BX936447.2 non-coding downstream 1859007 40278147 ~ 40278263 (+)

Expression



Co-expression Network