XLOC_037338 (cyp27a1.2)


Basic Information

Item Value
gene id XLOC_037338
gene name cyp27a1.2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007120.7
NCBI id CM002893.2
chromosome length 56459846
location 38420012 ~ 38425491 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00073463
GTCGTTAACCTCATTTTTCTTTCTAAGTCCATAatggctgtttgttttgctttgagcTCTGCAGAAAGGCTCGGATGGTGTTTTCTGAGACCCACGGCAGCGGCCACAGGCTTCAGGAGTGCAGCAGGAAATGCTGCGGCTGCTTCTGTCAGTGTCCAGGACGGCCACAGAAAGCTGAAGACTGAGGCTGACCTTCCAGAGATCAAAATCTTTACCATGTTGTATCAAATGCTCTTCAAAGGTTACCTCAACAGCGTACATGAGCTACAGTTATATCAAAAACAGGTTTATGGCCCCTTGTGGAAAATTAATGCTGGAAACCTCCAAGGCATTTCAATAAGCAGTGTGGAGCTGCTGGAAGAACTCCTTCGAAAAGATGAGAAATATCCATGCAGAGGATACATGACTCTGTGGACAGAGCACCGGGACTTAAGAGGCATTAGCTATGGCCCTTTCACAGAGTAAAAACAAAGGATTTGTATAAATAACACTCGTTTTACAGCCCATTTAAAAAGCAAGTTGGCAAAGTTGGCTAATGTAGCTGTTTCGTGTTATACAAAATCATGaactcggtaacactttacaataggttcattagttaatgcatttgctaacatgaactaatcatgaacaacacttgtacagcatttattaaccataattgaacatttactaatgcattattaacatccaaactcacaatgaactactgtattttcattaactaacgttaactaacatgaacaagaactgtagtaaatgtattgttcattgtttgttcatgttagtaaatgcattaagtaacattaactaatgaaccttattgtaaagtgtgaccatgaaCTCTTATCAATTTCCGCTGTTCAGTTTCTCATATGAAAA
>TCONS_00073464
TTCTTTCTAAGTCCATAatggctgtttgttttgctttgagcTCTGCAGAAAGGCTCGGATGGTGTTTTCTGAGACCCACGGCAGCGGCCACAGGCTTCAGGAGTGCAGCAGGAAATGCTGCGGCTGCTTCTGTCAGTGTCCAGGACGGCCACAGAAAGCTGAAGACTGAGGCTGACCTTCCAGAGATCAAAATCTTTACCATGTTGTATCAAATGCTCTTCAAAGGTTACCTCAACAGCGTACATGAGCTACAGTTATATCAAAAACAGGTTTATGGCCCCTTGTGGAAAATTAATGCTGGAAACCTCCAAGGCATTTCAATAAGCAGTGTGGAGCTGCTGGAAGAACTCCTTCGAAAAGATGAGAAATATCCATGCAGAGGATACATGACTCTGTGGACAGAGCACCGGGACTTAAGAGGCATTAGCTATGGCCCTTTCACAGAAGAAGGAGAGAAATGGTACAAACTGCGGGCGGTGCTGAACAAACGCATGCTTCATCCAAAGGACTCGGTTCAGTATGGAGATGTGGTGAATGCAGTGATCACAGACTTCATCAAACGCATTTACTATCTGCGGGAGATGAGTCCTACAGGGGATCTGGTGTCTAATCTGACCAATGAGCTTTACCGATTCTCTCTTGAAGGGATTGCGTCCATTCTCTTCGAGACGCGCATTGGCTGTCTGGAGAAAGAAATTCCTGCTGAGACACAaaagtttattaatttcattgctCAAATGTTCACCTACAGCATGCACGTGGCCCTTCTGCCCAACTGGACCCGCAAATATTTCCCATTCTGGCAGAAGTACATTGATGGCTGGGATGGCATATTCAAGTTCGGCACAAAAATGATTGACATGAAGATGGAGGCCATTCAGAAGCGTGTAGATACCAATCAGGATGTTGCTGGAGAGTATCTCACATACCTGCTTTCTAATGGCAAGATAAGCAGGAAAGACGTTTATGGAAGTGTATCTGAGCTGCTGCTGGCTGGAGTCGACTCAACCTCCAACACCATGTTGTGGGCTCTTTATCTTCTCTCAAAAGACCCAGAAGCTCAGGAGACTTTGTATCAGGAGGTAACCAAGGTCTTAAAGGATGACAGAATCCCAACAGCAGAAGAAGTGAACAGCATGCCTTTCCTCAAAGCTGTCATCAAGGAAACATTAAGACTGTATCCGGTGGTGCCTGTAAATTCCCGTCTTATTGCAGAAACTGAAGTCGTCATTGGTGAATACTTTTTTCCTAAAAAGACAACATTCACTTTGTGCCACTATGTAATCAGCCGTGATGAGAAAGTCTTCCCAGAACCACAGAAGTTCAAACCTGAGCGCTGGCTGCGAGACGGCAGAACCAGACCAAACCCGTTTGGGTCAATCCCATTTGGATTTGGAGTCAGAGCCTGTGTCGGTCGTCGCATTGCTGAACTGGAAATGCATCTGGCTTTGGCAAGGCTAATCAAGTTGTTTGAAATGCGACCAGACCCGACTGTAGGTGAAGTTAAGGCAAACTTTCGTTCAGTGCTTGTTCCCAACAAAAAGGTCAATCTGCACTTTGTGGAGAGACAGAAGACTGAAACATAGCTCAACTAGACATGAGCTGCATATGTACATAAGGAATTATCAGCTGAAGTGATTCATGTGAATTTGTCAATGGCTTTAACTGAATATGATTCTTCTTTTCTTTGTTAAAGACCCTGTACAAGAGTATGAAGAATATACTTTGTCACccaataatatttatttcattgtgATGATAGCCATGAAAATATTTTATAGATGTTAAAATCAATTAAACTTTATAATGAATTCAAAA

Function

symbol description
cyp27a1.2 Predicted to enable cholesterol 26-hydroxylase activity and vitamin D3 25-hydroxylase activity. Predicted to be involved in calcitriol biosynthetic process from calciol and cholesterol metabolic process. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in cerebrotendinous xanthomatosis. Orthologous to human CYP27A1 (cytochrome P450 family 27 subfamily A member 1).

GO:

id name namespace
GO:0008203 cholesterol metabolic process biological_process
GO:0036378 calcitriol biosynthetic process from calciol biological_process
GO:0009074 aromatic amino acid family catabolic process biological_process
GO:0046395 carboxylic acid catabolic process biological_process
GO:0044282 small molecule catabolic process biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0016054 organic acid catabolic process biological_process
GO:0005739 mitochondrion cellular_component
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen molecular_function
GO:0004497 monooxygenase activity molecular_function
GO:0005506 iron ion binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0016491 oxidoreductase activity molecular_function
GO:0031073 cholesterol 26-hydroxylase activity molecular_function
GO:0020037 heme binding molecular_function
GO:0030343 vitamin D3 25-hydroxylase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-081104-511 Predicted to enable cholesterol 26-hydroxylase activity and vitamin D3 25-hydroxylase activity. Predicted to be involved in calcitriol biosynthetic process from calciol and cholesterol metabolic process. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in cerebrotendinous xanthomatosis. Orthologous to human CYP27A1 (cytochrome P450 family 27 subfamily A member 1).

Ensembl:

ensembl_id ENSDARG00000069186

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00073463 False 882 lncRNA 0.39 2 38420012 38421036
TCONS_00073464 True 1818 mRNA 0.44 9 38420028 38425491

Neighbor

gene id symbol gene type direction distance location
XLOC_037337 cyp27a7 coding upstream 872 38408991 ~ 38419140 (+)
XLOC_037336 bcs1l coding upstream 12836 38399912 ~ 38407176 (+)
XLOC_037335 plcd4b coding upstream 29022 38369872 ~ 38390990 (+)
XLOC_037334 ddx18 coding upstream 67792 38314466 ~ 38352220 (+)
XLOC_037333 tfcp2l1 coding upstream 108262 38292919 ~ 38311750 (+)
XLOC_037339 CYP27A1 coding downstream 2081 38427572 ~ 38433916 (+)
XLOC_037340 cyp27a1.4 coding downstream 21013 38446504 ~ 38457413 (+)
XLOC_037341 mcm3ap coding downstream 32315 38457806 ~ 38500391 (+)
XLOC_037342 lmln coding downstream 77033 38502524 ~ 38516727 (+)
XLOC_037343 osbpl11 coding downstream 99390 38524881 ~ 38556328 (+)
XLOC_037331 BX548038.2 non-coding upstream 258623 38161263 ~ 38161389 (+)
XLOC_037330 BX548038.1 non-coding upstream 259440 38160446 ~ 38160572 (+)
XLOC_037326 NA non-coding upstream 395951 38021890 ~ 38024061 (+)
XLOC_037325 CU896658.1 non-coding upstream 542462 37877434 ~ 37877550 (+)
XLOC_037322 NA non-coding upstream 911739 37506959 ~ 37508273 (+)
XLOC_037349 CR376853.1 non-coding downstream 361437 38786928 ~ 38787044 (+)
XLOC_037351 CR812481.1 non-coding downstream 584941 39010432 ~ 39014598 (+)
XLOC_037353 NA non-coding downstream 1437762 39863253 ~ 39865672 (+)
XLOC_037354 BX255912.2 non-coding downstream 1712006 40137497 ~ 40137612 (+)
XLOC_037355 BX936447.2 non-coding downstream 1852656 40278147 ~ 40278263 (+)

Expression


Co-expression Network