XLOC_037339 (CYP27A1)



Basic Information


Item Value
gene id XLOC_037339
gene name CYP27A1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007120.7
NCBI id CM002893.2
chromosome length 56459846
location 38427572 ~ 38433916 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00073465
CTTCGTTCTGTGTCCATAatggctgtttgttttgctttgagcTCTGCAGAAAGGCTCGGATTCGGTTTTCTGAGACCCACGGCAGCGGCCACAGGCTTCAGGAGAGCAGCAGGAAATGCTGCGGCTGCTTCTGTCAGTGTCCAGGACGGCCACAGAAAGCTGAAGACTGAGGCTGACCTTCCAGAGATCAAAATCTTTACCATGTTGTATCAAATGCTCTTCAAAGGGTACCTCAACAGCATACATGAGCTACAGATATATCAAAAACAGGTTTATGGCCCCTTGAGCAAAATCAATTCTGGAAACCTCCAAGGCATTTCAATAAGCAGTGTGGAGCTACTGGAAGAACTCCTTCGAAAAGATGAGAAATATCCATGCAGAGGATACATGACTCTGTGGACAGAGCACCGGGACTTAAGAGGCATTGGCTATGGCCCTTTCACagaAGAAGGAGAGAAATGGTACAAACTACGAGCGGTGCTGAACAAACGCATGCTTCATCCAAAGGACTCGCTTCAGTATGGAGATGTGGTGAATGCAGTGATCACAGACTTCATCAAACGCATTTACTATCTGCGGGAGATGAGTCCTACAGGGGATCTAGTCTCTAATCTGACCAATGAGCTTTACCGATTCTCCCTTGAAGGGATTGCGTCCATTCTCTTCGAGACGCGCATTGGCTGTCTGGAGAAAGAGATTCCTGTTGAGACTCAAGAGTTTATTAATTCAATTGCTCAAATGTTCACCTACAGCATGCACGTGGCCCTTCTGCCCAACTGGACCCGCAATTACTTCCCATTCTGGCAGAAGTACATTGATGGCTGGGATGGCATATTCAAGTTCGGCACAAAAATGATTGACATGAAGATGGAGGCCATTCAGAAGCGTGTAGATACCAATCAGGAGGTTGCTGGAGAGTATCTCACATACCTGCTTTCTAGTGGCAAGATGAGCAGCAAAGATGTTTATGGAAGTGTATCTGAGCTGCTGCTGGCTGGAGTCGACACAACCTCCAACACCATGTTGTGGGCTCTTTATCTTCTCTCAAAAGACCCAGCAGCTCAGGAGACTTTGTATCAGGAGGTAACCAAGGTCTTAAAGGATGACAGAATCCCAACAGCAGAAGAAGTGAACAGCATGCCTTTCCTCAAAGCCGTCATCAAGGAAACATTAAGACTGTATCCGGTGGTGCCTGTAAATTCCCGTCTTATTGCAGAAACCGAAGTCGTCATTGGTGAATACTTTTTTCCTAAAAAGacAACATTCAATCTGTGCCACTATGCAATCAGCCATGATGAGAAAGTCTTCCCAGAACCACAGAAGTTCAAACCTGAGCGCTGGCTGCGAGACGGCAGAACCAGACCAAACCCGTTTGGGTCAATCCCATTTGGATTTGGAGTCAGAGCCTGTGTCGGTCGTCGCATTGCTGAACTGGAAATGCATCTGGCTTTGGCAAGGCTAATCAAGTTGTTTGAAATGCGACCAGACCCGACTGTAGGTGAAGTTAAGGCAAACTTTCGTTCAGTGCTTGTTCCTAACAAAAAGGTCAATCTGCACTTTGTGGAGAGACAGAAGACTGAAACATAGCTCAACTAGACATGAGCTGCATATGTACATAAGGAATCATCAGCTGAAGTGATTCATGTGAATTTGTCAACGGCTTTAACTGAATATGATTCTTCTGTTCTTTGTTAAAGACCCTGTACAAGAGTATGAAGAATATACTTTGTCactcaataatatttattttattttgataatagccatgaaaatattttatatatgtaaaaatcaATTAAACTTTATAATGATTCAAAA

Function


symbol description
cyp27a1 Enables heme binding activity and monooxygenase activity. Involved in bile acid biosynthetic process; calcitriol biosynthetic process from calciol; and cholesterol catabolic process. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrion. Implicated in cerebrotendinous xanthomatosis. Biomarker of non-alcoholic steatohepatitis.

GO: NA

KEGG:

id description
ko00120 Primary bile acid biosynthesis
ko03320 PPAR signaling pathway
ko04979 Cholesterol metabolism
ko00199 Cytochrome P450

Ensembl:

ensembl_id ENSDARG00000088013

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00073465 True 1818 mRNA 0.44 9 38427572 38433916

Neighbor


gene id symbol gene type direction distance location
XLOC_037338 cyp27a1.2 coding upstream 2081 38420012 ~ 38425491 (+)
XLOC_037337 cyp27a7 coding upstream 8432 38408991 ~ 38419140 (+)
XLOC_037336 bcs1l coding upstream 20396 38399912 ~ 38407176 (+)
XLOC_037335 plcd4b coding upstream 36582 38369872 ~ 38390990 (+)
XLOC_037334 ddx18 coding upstream 75352 38314466 ~ 38352220 (+)
XLOC_037340 cyp27a1.4 coding downstream 12588 38446504 ~ 38457413 (+)
XLOC_037341 mcm3ap coding downstream 23890 38457806 ~ 38500391 (+)
XLOC_037342 lmln coding downstream 68608 38502524 ~ 38516727 (+)
XLOC_037343 osbpl11 coding downstream 90965 38524881 ~ 38556328 (+)
XLOC_037344 snx4 coding downstream 154165 38588081 ~ 38621202 (+)
XLOC_037331 BX548038.2 non-coding upstream 266183 38161263 ~ 38161389 (+)
XLOC_037330 BX548038.1 non-coding upstream 267000 38160446 ~ 38160572 (+)
XLOC_037326 NA non-coding upstream 403511 38021890 ~ 38024061 (+)
XLOC_037325 CU896658.1 non-coding upstream 550022 37877434 ~ 37877550 (+)
XLOC_037322 NA non-coding upstream 919299 37506959 ~ 37508273 (+)
XLOC_037349 CR376853.1 non-coding downstream 353012 38786928 ~ 38787044 (+)
XLOC_037351 CR812481.1 non-coding downstream 576516 39010432 ~ 39014598 (+)
XLOC_037353 NA non-coding downstream 1429337 39863253 ~ 39865672 (+)
XLOC_037354 BX255912.2 non-coding downstream 1703581 40137497 ~ 40137612 (+)
XLOC_037355 BX936447.2 non-coding downstream 1844231 40278147 ~ 40278263 (+)

Expression



Co-expression Network