XLOC_037340 (cyp27a1.4)


Basic Information

Item Value
gene id XLOC_037340
gene name cyp27a1.4
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007120.7
NCBI id CM002893.2
chromosome length 56459846
location 38446504 ~ 38457413 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00073466
CTTCGTTCTGTGTCCATAATGGCTGTTAGTTTTGCTTTGAGCTCTGCAGAAAGGCTCGGATGGTGTTTTCTGAGACCCACGACAGCGGCCACAGGCTTCAGGAGAGCAGCAGGAAATTCTGCGGCTGCTTCTGTCAGTGTCCAGGACGGCCACAGAAAGCTGAAGACTGAGGCTGACCTTCCAGAGATCAAAATCTTTACCATGTTGTATCAAATGCTCTTCAAAGGGTACCTCAACAGCGTACATGAGCTACAGTTATATCAAAAACAGGTTTATGGCCCCTTGTGGAAAATTAATGCTGGAAACCTCCAAGGAATTTCAATAACCAGTGTGGAGCTACTGGAAGAACTTCTTCGAAAAGATGAGAAATATCCATGCAGAGGATACATGACTCTGTGGACAGAGCATCGGGACTTAAGAGGCATTAGCTATGGCCCTTTCACAGAAGAAGGAGAGAAATGGTACAAACTGCGGGCGGTGCTGAACAAACGCATGCTGCATCCAAAGGACTCGCTTCAGTATGGAGATGTGGTGAATGCAGTGATCACAGACTTCATCAAACGCATTTACTATCTGCGGGAGATGAGTCCTACAGGGGATCTGGTCTCTAATCTGACCAATGAGCTTTACAGATTCTCCCTTGAAGGGATTGCGTCCATTCTCTTCGAGACGCGCATTGGCTGTCTGGAGAAAGAGATTCCTGCTGAGACACAAGAGTTTATTAATTCCATTGCTCAAATGTTCACCTACAACATGCACGTGGCCCTTCTGCCCAACTGGACCCGCAATTATTTGCCTTTCTGGCAGAAGTACATTGATGGCTGGGATGGCATATTTAAGTTCGGCACAAAAATGATTAACTTGAAGATGGAGGCCATTCAGACGCGTCTAGATACCAATCAGGAGGTTGCTGGAGAGTATCTCACATACCTGCTTTCTAGTGGCAAGATGAGCTGCAAAGATGTTTATGGAAGTGTATCTGAGGTGCTGCTGGCTGGAGTCGACACAACCTCCAACACCATGTTGTGGGCTCTTTATCTTCTCTCAAAAGACCCAGCAGCTCAGGAGACTTTGCATCAGGAGGTAACCAAGGTCTTAAAGGGTGACAGAATCCCAACAGCAGAAGAAGTGAACAGCATGCCTTTCCTCAAAGCCGTCATCAAGGAAACATTAAGACTGTATCCTGTGGTGCCTGTAAATTCCCGTCTTATTGCAGAAAGTGAAGTCATCATTGGTGAATACCTTTTTCCTAAAAAGACCACATTTAATCTGTTCCACTATGCAATCAGCCACGATGAAAAAGTCTTCCCAGAACCACAGAAGTTCAAACCTGAGCGCTGGCTGCGAGACGGCAGAACCAGACCAAACCCGTTTGGGTCAATCCCATTTGGATTTGGAGTCAGAGCCTGTGTCGGTCGTCGCATTGCTGAACTGGAAATGCATCTGGCTTTGGCAAGGCTAATCAAGTTGTTTGAAATGCGACCAGACCCGACTGTAGGTGAAGTTAAGGCAAACTTTCGTTCAGTGCTTGTTCCCAACAAAAAGGTCAATCTGCACTTTGTGGAGAGACAGAAGACTGAAACATAGCTCAACTAGACATGAGCTGCATATGTACATAAGGAATTATCAGCTGAAGTGATTCATGTGAATTTGTCAACGGCTTTAACTGAATATGATTCTTCTGTTCTTTGTTAAAGACCCTGTACAAGAGTATGAAGAATATACTTTGTCactcaataatatttatttcattctgATAATAGCCATGAAAATATTTTATAGATGTAAAAATCAATTAAACTTTATAATGAATTCAAAA

Function

symbol description
cyp27a1.4 Predicted to enable cholesterol 26-hydroxylase activity and vitamin D3 25-hydroxylase activity. Predicted to be involved in calcitriol biosynthetic process from calciol and cholesterol metabolic process. Predicted to be active in mitochondrion. Is expressed in liver. Human ortholog(s) of this gene implicated in cerebrotendinous xanthomatosis. Orthologous to human CYP27A1 (cytochrome P450 family 27 subfamily A member 1).

GO:

id name namespace
GO:0008203 cholesterol metabolic process biological_process
GO:0036378 calcitriol biosynthetic process from calciol biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0005739 mitochondrion cellular_component
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen molecular_function
GO:0004497 monooxygenase activity molecular_function
GO:0005506 iron ion binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0016491 oxidoreductase activity molecular_function
GO:0031073 cholesterol 26-hydroxylase activity molecular_function
GO:0020037 heme binding molecular_function
GO:0030343 vitamin D3 25-hydroxylase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-030131-1060 Predicted to enable cholesterol 26-hydroxylase activity and vitamin D3 25-hydroxylase activity. Predicted to be involved in calcitriol biosynthetic process from calciol and cholesterol metabolic process. Predicted to be active in mitochondrion. Is expressed in liver. Human ortholog(s) of this gene implicated in cerebrotendinous xanthomatosis. Orthologous to human CYP27A1 (cytochrome P450 family 27 subfamily A member 1).

Ensembl:

ensembl_id ENSDARG00000055159

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00073466 True 1819 mRNA 0.44 9 38446504 38457413

Neighbor

gene id symbol gene type direction distance location
XLOC_037339 CYP27A1 coding upstream 12588 38427572 ~ 38433916 (+)
XLOC_037338 cyp27a1.2 coding upstream 21013 38420012 ~ 38425491 (+)
XLOC_037337 cyp27a7 coding upstream 27364 38408991 ~ 38419140 (+)
XLOC_037336 bcs1l coding upstream 39328 38399912 ~ 38407176 (+)
XLOC_037335 plcd4b coding upstream 55514 38369872 ~ 38390990 (+)
XLOC_037341 mcm3ap coding downstream 393 38457806 ~ 38500391 (+)
XLOC_037342 lmln coding downstream 45111 38502524 ~ 38516727 (+)
XLOC_037343 osbpl11 coding downstream 67468 38524881 ~ 38556328 (+)
XLOC_037344 snx4 coding downstream 130668 38588081 ~ 38621202 (+)
XLOC_037345 znf148 coding downstream 167065 38624478 ~ 38641307 (+)
XLOC_037331 BX548038.2 non-coding upstream 285115 38161263 ~ 38161389 (+)
XLOC_037330 BX548038.1 non-coding upstream 285932 38160446 ~ 38160572 (+)
XLOC_037326 NA non-coding upstream 422443 38021890 ~ 38024061 (+)
XLOC_037325 CU896658.1 non-coding upstream 568954 37877434 ~ 37877550 (+)
XLOC_037322 NA non-coding upstream 938231 37506959 ~ 37508273 (+)
XLOC_037349 CR376853.1 non-coding downstream 329515 38786928 ~ 38787044 (+)
XLOC_037351 CR812481.1 non-coding downstream 553019 39010432 ~ 39014598 (+)
XLOC_037353 NA non-coding downstream 1405840 39863253 ~ 39865672 (+)
XLOC_037354 BX255912.2 non-coding downstream 1680084 40137497 ~ 40137612 (+)
XLOC_037355 BX936447.2 non-coding downstream 1820734 40278147 ~ 40278263 (+)

Expression


Co-expression Network