XLOC_037364 (slc40a1)


Basic Information

Item Value
gene id XLOC_037364
gene name slc40a1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007120.7
NCBI id CM002893.2
chromosome length 56459846
location 41103127 ~ 41113878 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00073519
AACACGGTGCTCGGCTGCATCCTTGCGAGCGGCTCTGGCCATTTCGGGaattatatgtttttattcaCATAGTTGTTCTAGAAAGGTTATTTCTCTCCGACTTCAGCTACAGTGATAGCTAAGTTTGGAGAGGAGAGAAGGGAGATATTCGTGATTTGCGCAGGAATATATTTGCAGCGAGGATTTACTTTGCCCGAGCCTTACAAAGGAGTTCAAATCCcggcgagaaaaaaaaaaacacaatcgaTAAAAAACGCACAATGGACAGCCCTGCATCAAAGAAACCTCGCTGTGAGAGGTTCCGCGAATTCTTCAAGTCTGCAAAATTCCTCATTTACGTCGGACATGCCCTCTCGACATGGGGGGATCGGATGTGGAATTTTGCTGTGGCTGTGTTTCTGGTGGAGCTGTATGGCAATAGTTTACTCCTGACAGCCGTGTATGGACTGGTGGTCGCGGGGTCCGTGCTCTTACTGGGCGCTATTATTGGTGACTGGGTTGACAAAAACCCCAGACTAAAAGtGGCACAGACATCTTTGGTTGTCCAGAACAGTGCTGTCATTCTCTGTGGTGCCCTTTTGATGGCTGTTTTCCAGTTCAAACAACAGCTTTCTAGCATGTATGATGGATGGTTGCTGACAACATGCTACATAATGGTCATCTCCATTGCTAATATCGCTAACCTGGCCAGCACAGCTATGTCCATCACCATCCAAAGAGACTGGGTTGTGGTTGTGGCTGGAGATGATCGGAGCAAATTGGCAGatatGAATGCAACTGTCAGAATAATTGACCAGTTGACCAACATTCTGGCACCGATGCTTGTGGGCCAGATCATGGCATTTGGCTCACacttcattggctgtggttttaTCTCGGGCTGGAACTTGTTCTCCATGTGCCTGGAGTATTTCCTGCTTTGGAAAGTTTATCAGAAAACTCCAGCGCTTGCCTTTAAGGCAGGACAGAAGGATAGCGATGACCAAGAGCTGAAACACCTCAACATACAAAAAGAAATTGGAAACACTGAAAGCCCGGTCGAAGCCTCCCAACTGATGACTGAAAGCTCCGAGACCAAGAAGGACACCGGCTGCTGCTACCAAATGGCAGAGCCCATCCGTACCTTTAAAGATGGCTGGGTAGCCTACTACAATCAATCCATCTTCTTCGCCGGCATGTCTCTGGCTTTCCTATACATGACCGTTTTGGGCTTCGACTGCATCACCACAGGCTATGCATACACTCAGGGCCTGAATGGCTCTGTGCTCAGTCTCCTCATGGGAGCCTCAGCTGTATCTGGGATCTGTGGGACAGTGGCCTTCACCTGGATCCGAAAGAAGTGCGGCCTCATCAGGACGGGCTTCATTGCTGGAGTCACCCAGCTGTCCTGCCTCACGCTGTGTGTAGCATCTGTCTTCGCCCCTGGCAGCCCTTTCGATCTCAGCGTCTCGCCCTTCGAAGAGGTCTTAAGACATCTGTTTGGAGACAGCGGCTCGCTGCGTGAGAGTCCTACATTCATTCCTACAACTGAACCCCCGATTCAGGCCAACGTCACCGTTTTTGAGGAAGCCCCCCCAGTAGAGTCCTACATGTCTGTCGGGCTTCTCTTTGCCGGTGTTATTGCTGCTAGAGTTGGTCTTTGGTCCTTCGACTTGACCGTGACCCAACTGATCCAAGAGAATGTGATTGAGTCCGAGAGAGGAGTCATCAATGGCGTCCAGAACTCCATGAATTATCTTCTCGATCTCCTGCACTTCATCATGGTCATCCTTGCACCAAATCCTGAAGCCTTTGGTCTTCTTGTAATCATCTCCGTTTCCTTCGTGGCTATGGGACATATGATGTATTTCAGGTTTGCCTATAAAAGCCTTGGAAGCCGACTCTTCCTGTTCTGTTCCCCCGAGCAGAAGCCAGATCCCAACATTCCCTCACTTCCAAACTCTGTATAGCTTTTTAAAGAGACCGTAGGCCATTTCTACAAGAGCGTGGCTTGCTGTGTTCTTCCAGAACCTTGCCAGGATCCCATCTGTTTTACTAACATGCATGCTTTTGCTGCTTGCAGTGCTGTGCATTGAGTAAATATCCTCTGCCATAGGCTAAAATAACAAAGAGAAGGAGCTCTACTTAGCATAGCATACTTCACTTCTCACTATCATGTTCAAGGTGCTGTAAAAATGCCATAGAAGCAACCGTAGGAGGAAATATATACATGGAAACTACGGTTCTATCATGCTTTAATGACTTTTGTAAGAGCTCCAAAGCaaaaattagcatatttattcTACTTTTacgttttatattgttttttttttcaactttatgGTCGTAGTTAACCTTCAGACTGGTTATGACAGTTTTGCAATGTGCTCTACTTATGATAGTGTAGTTTTGTAATGTTTGTCCCTTCTTCCAAGCCTTGGTTAAAGTCTCTTTAATAGCTATTAAGAGTGCGCTAGTTATACATTCAGGTAAGCCTATATAAtgcctatatatttatatacacgtGTAGTCAGTATTCTTTATCTCAGCTTCGGTGGTGCTACGTTGTTTCAACTCTTTTGGAAAGCCATGCAGGCGGTTTATACATGTAACCAAAGTGGGTTTTTTTGGCATCACGTGGAAGTGAGGGAATTGCCGTTTTTTTATCGTGTTAAACattccatattattattattaccggTGTGATGATTTCTTGGAGATTTCGGCGCTGATAGGCTCCCCATCGCAGCAAGAGATTTTAGCGCTAGGTATTTTTGCTCCTGTTTGATTTGAAAGTGATTTTCGCACAtaattcttgtttttatttgcaaAGATTGTTACACATGCACTTTACATGATTAATATACGTTTTCCATTACGAAACAAGCGCAACAAGACACTTCAGGTATTACGATATTTGCACAATACACAAAACCTGTCGCCGAAGTTCACGGCCAGGCAGGAAATCTGATATTTTTACATGcaaatttatttcaaaatggGATTTTCAAAGTACATTAACCTCAAACTTCATGATTTTTACCTTCCTATATAAGACACCACACCTCATACGCTAATCTAGATTTTTTATAATACAAAGTAAAGGTTACAGACCTGTTCTATTAGCTTAGATGAAAGCCACAATCATAGAAGTACTACTAACATCCTTTTAAAACCACAGCTGGCTcgacatagatatatatatatatatatatatgaggtgtTTTATAATAGTTGTGTAATATTGATGTTGGACACCAGCGGGAATCCACCATATGCACAGAACAGAGAAGGGATTATTGAGTCCAGTGTGTAAACGGCTGGTTTGCAGCGCAGCTGGTTCCAAACACAGGTGCCAAGTCACACTTGACTTGCTAAGTTAGCGTTTTCTTTAATGTGTGAGAACTACTTCATGAGGCCCCAACGAACACACTGTCAGTCTTTCATTGTGTCAGTCTTTCTGTGAATGTGAAGCCTTATTTAcatctgtaaaatatttttttatattcttatGTTGACTAGTTTTGTTTCAATCGGGTTTATCCTCCTTTGTAAGGCCACAGATTTCCCCCTTTTAGACAAGAGAAGTAAACACGTTTGCAATAAATTGTACTTTCGACACCCAGTTGAATGTAACGGAAGAACCTAGATTATTCTTTATATAAGCATATTGATTCTGTTCATGTTTGGTGGCATATTTGCAATAATTGTGGTTCACACTCCATCGCAGTGGGAGGATTATAGAACTTTAGTCTTGTATTGTATCTCACTTCGACTGAAATAAACAGATTTGTATCTAAA

Function

symbol description
slc40a1 Enables iron ion transmembrane transporter activity. Acts upstream of or within several processes, including bone mineralization; hemoglobin biosynthetic process; and hemopoiesis. Predicted to be integral component of membrane. Predicted to be active in basolateral plasma membrane. Is expressed in digestive system; gill; nervous system; solid lens vesicle; and yolk syncytial layer. Used to study iron deficiency anemia. Human ortholog(s) of this gene implicated in hemochromatosis type 4. Orthologous to human SLC40A1 (solute carrier family 40 member 1).

GO:

id name namespace
GO:0006879 cellular iron ion homeostasis biological_process
GO:0034755 iron ion transmembrane transport biological_process
GO:0043362 nucleate erythrocyte maturation biological_process
GO:0042541 hemoglobin biosynthetic process biological_process
GO:0055072 iron ion homeostasis biological_process
GO:0046688 response to copper ion biological_process
GO:0030282 bone mineralization biological_process
GO:0035162 embryonic hemopoiesis biological_process
GO:0006811 ion transport biological_process
GO:0006826 iron ion transport biological_process
GO:0010039 response to iron ion biological_process
GO:0016020 membrane cellular_component
GO:0016323 basolateral plasma membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0017046 peptide hormone binding molecular_function
GO:0005381 iron ion transmembrane transporter activity molecular_function

KEGG:

id description
ko04216 Ferroptosis
ko04978 Mineral absorption
ko02000 Transporters

ZFIN:

id description
ZDB-GENE-000511-8 Enables iron ion transmembrane transporter activity. Acts upstream of or within several processes, including bone mineralization; hemoglobin biosynthetic process; and hemopoiesis. Predicted to be integral component of membrane. Predicted to be active in basolateral plasma membrane. Is expressed in digestive system; gill; nervous system; solid lens vesicle; and yolk syncytial layer. Used to study iron deficiency anemia. Human ortholog(s) of this gene implicated in hemochromatosis type 4. Orthologous to human SLC40A1 (solute carrier family 40 member 1).

Ensembl:

ensembl_id ENSDARG00000000241

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00073519 True 3780 mRNA 0.43 8 41103127 41113878

Neighbor

gene id symbol gene type direction distance location
XLOC_037363 zgc:136439 coding upstream 19946 41080029 ~ 41083181 (+)
XLOC_037362 osgepl1 coding upstream 57254 41040294 ~ 41045873 (+)
XLOC_037361 ormdl1 coding upstream 68953 41024973 ~ 41034174 (+)
XLOC_037360 mstnb coding upstream 159990 40939336 ~ 40943137 (+)
XLOC_037358 hibch coding upstream 178184 40874194 ~ 40924943 (+)
XLOC_037365 stat4 coding downstream 42409 41156287 ~ 41208343 (+)
XLOC_037366 stat1b coding downstream 105089 41218967 ~ 41247197 (+)
XLOC_037367 BX649377.1 coding downstream 135579 41249457 ~ 41266843 (+)
XLOC_037368 nemp2 coding downstream 345881 41459759 ~ 41481650 (+)
XLOC_037369 BX571827.3 coding downstream 396070 41509948 ~ 41598827 (+)
XLOC_037359 BX323586.1 non-coding upstream 205944 40895649 ~ 40897183 (+)
XLOC_037355 BX936447.2 non-coding upstream 824864 40278147 ~ 40278263 (+)
XLOC_037354 BX255912.2 non-coding upstream 965515 40137497 ~ 40137612 (+)
XLOC_037353 NA non-coding upstream 1237455 39863253 ~ 39865672 (+)
XLOC_037351 CR812481.1 non-coding upstream 2088529 39010432 ~ 39014598 (+)
XLOC_037370 BX571827.2 non-coding downstream 479618 41593496 ~ 41593610 (+)
XLOC_037372 dre-mir-732 non-coding downstream 569048 41682926 ~ 41683010 (+)
XLOC_037374 dre-mir-26a-1 non-coding downstream 619655 41733533 ~ 41733610 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000009_11803818_11808988 SLC40A1 coding CI01000009 null 11802384 ~ 11809235 (+)
bowfin (Amia calva) AMCG00001104 slc40a1 coding CM030137.1 CM030137.1 15241652 ~ 15251730 (-)