XLOC_037396 (frzb)



Basic Information


Item Value
gene id XLOC_037396
gene name frzb
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007120.7
NCBI id CM002893.2
chromosome length 56459846
location 44832032 ~ 44839148 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00073581
CCCTCAGCATTTCCACAAGAGAATTTCTTCAGCTTTTTTTCTTAACTCCAATTATTTCATCGACAATTTCAAGAAGAGATGAGCTTTTGTGCTCTACGCATCCGATGCATTCCCTCAGAATGGTGAAGTTAGTTTGAGGAACTTTCTTTTGGCACCGCCGGGGAGCTTTTTACGCGCTAGAGTCTCCAGAACACCTCCGCATGTCATTCTTCTATCAACTCcgctttttttaatcattatttttttatatttaatgcaaAACATGTTTTCCTACGAGATGTTCATCTGCGTCCTGGCCTTCGCATGTCTCCTGGAGATCCCGCGGGGCACCGGAGCCGCGTCCTGCGAGCCCATCCGCATCCCCATGTGCAAATCCATGCCCTGGAACATGACCAAGATGCCCAACCACCTCCATCACAGCACGCAAGCCAACGCCGTCCTGGCCATCGAGCAGTTTGAAGGGCTCCTGGGCACTCAGTGCAGCGCGGATCTGCTGTTCTTCTTGTGCGCCATGTACGCGCCCATCTGCACCATCGACTTCCAGCACGACCCGATCAAGCCTTGCAAGTCCGTGTGCGAGCGGGCCAAGTGCGGCTGCGAGCCGGTCATGAAGAGGTACAACCATACGTGGCCGGAGAGTCTGGCCTGCGAGGAGCTGCCGGTGTACGACCGAGGGGTCTGCATCTCACCTGAGGCCATAGTCAAAGCGGAGGGGCCAGATAATTCTTACTACCAAGACCCTGCGAAATGTAACCCTGAGGGAAACCCAGACTTCCCAATGGATTCACACAATACTAACTGCAAAGGAGCAAAtgATCGGTGCAAATGCAAGTCTGTGAAATTTAATCAAAAGACATATTCAAAGAATAATTACAATTATGTGATTCGTGCAAGAGTGAAGGAGATCAGGATTAGAAATCATGACCTGAGCGCCATTGTGGAGGTCAAAGAAGTTCTGAAGTCATCTCTGGTCAACATCCCTCGAGACACGGTCACTCTGTACTATAACTCCGGCTGTCTGTGTCCTCCGCTCACAGCCAACGACGAGTACATCATCATGGGTTATGAAAATGAGGAGCGCTCCAGGCTGCTGCTCATCGACAGATCCATTGCACAGAAGTGGAAAGAGAAAATAGGCCGGAAAGTAAAGCGCTGGGACCAGGCTGCAAACGGGAGGAGGACCAAATGGAACCACCACTAAACTGTCCTTGGAAATAAACCACACAGACAAGCCTGAAGAGCAGAAGGAGCAGAAACTGAAAAATTGCACTAttgtactttgttttgttttttcattttgtgtgtgtgtgtgtgtcgctttaatttttattgttgttatattcTCATTAACAAATTGTTGCCTTTGCACAAACAAAATGTTGGCTTGACATTGCTGTGTTAGGAATGGGTGGCGAGCAGTGTTGGGTAAGGTTACTTTTAAGAGTAATACATTACAGTCTTGAGTCACTTTTTTTCTAATATCTAAAAATGTTATTTAGGGGGGAAGGTAATGTAAAAGTATGTATTAtgttatttttgcttgtttatatCGAGATTAAGAAATGAATGGTCAAatggtcagttcacccaaaataaatgatttttaagtagctaaatgtgttactttttaaagaatgtaatgtaaaagtacactgtacacttacatttttaagctgaatcaaataaaCCTTTTAAGTCCATAATACTTATATTGTTAAActaacttaaaacagcttgcataacctATGACCTAAAACATGCTGTCAGGGCTAATTgatcatattattttttactgtgtatgaattgttattgttatttttaaagaatAAGATAGGCTCAAAGGATcagtttaccaaaaaaaaaaaagatttttaattaactaaatgTGTTCCTTTTTAAGAATGTAATGTAaaagtacacagtaaaaaatagacgcaacttaaaattttaaggcaacaaacctCAGGACATTTTTGAGCTAACTTGACTTAAATCAAGTCAAGTGCAGTAATTGGTTTGAAAGTTAAGTCATCTCAAAAATTTCCTAAATTTTTAATTTGAgtgtattgttattgttatttttaaagattaagaCAGATTTAAAGGGTCGGTTCACCTATCCCTTTAAGATTGTAATATAtcccttttaaaagtaactttactcAACACTGGTGGTGAATGTCGGGCAGCATTTTTTGCCCATTAAATTTAAAGGTATTTGAGGTGCTGGTGTCAttttgtcctaccttgtcagattgtcctacctcccatttaaaaagtaggtagcacattttgatgatgcaGTATGCAACcaatcagattttgctaccagtaTCAATTTTTTAAagtggagtagtgtgatatgaagctgtaatatcgaCCTAACCTATGCACCTAATAACCCCAATCTCAGAACCATTCAGATACAGTGTTCaatagcataatctgatgggtaggataaaatgtcaggacactaGTTCACATTGACATGATGCAGCTCTCTGCTTACAACAGCAAACAAACGCGCTCTCATGCTGAATTTTCCCCTCAGGAGGTTTTAACGTTCTTCACAAGAACAATGAACAGCGAGAGAAGCTGAGAGAGAATCTTTTTGGCAGAAGCACAGAGACGTTGAGATGATCCAAGACTTAGGAGTGTAACGTTATTGCGGACGACGAAAACAAGCTTTTGGGCTTTCTGAATGATGTTCCTTTTAAAGCATTTTACATGATAATTCCTGTAGTTCTGTTCTCTTGTAGATGTACGCTTGATCTTAATTGTCATTTGAAGTGTCATGCAATTGAAACTATTGTACAAACTGTACATAATGCTGCAAAAGTCCATTATTCAGCCTGGAACTCTTCACGGATGACATGAGCGTGTTTGTATGCGTCGCAAATGACGTCGATTTTGCAAACAGACATTTTGTCTTCGGAGACAAACAAGAAGATTTCTTCACTGTGTTTTGGGTTCAAGTAAAGAGGTTTCATCTTA

Function


symbol description
frzb Predicted to enable Wnt-protein binding activity. Acts upstream of or within chondrocyte proliferation. Predicted to be located in extracellular region. Predicted to be active in cytoplasm and extracellular space. Is expressed in several structures, including germ ring; head; hypochord; mesoderm; and nervous system. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma and osteoarthritis. Orthologous to human FRZB (frizzled related protein).

GO:

id name namespace
GO:0060070 canonical Wnt signaling pathway biological_process
GO:0035567 non-canonical Wnt signaling pathway biological_process
GO:0007275 multicellular organism development biological_process
GO:0090090 negative regulation of canonical Wnt signaling pathway biological_process
GO:0035988 chondrocyte proliferation biological_process
GO:0016055 Wnt signaling pathway biological_process
GO:0005576 extracellular region cellular_component
GO:0005615 extracellular space cellular_component
GO:0005737 cytoplasm cellular_component
GO:0017147 Wnt-protein binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-990715-1 Predicted to enable Wnt-protein binding activity. Acts upstream of or within chondrocyte proliferation. Predicted to be located in extracellular region. Predicted to be active in cytoplasm and extracellular space. Is expressed in several structures, including germ ring; head; hypochord; mesoderm; and nervous system. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma and osteoarthritis. Orthologous to human FRZB (frizzled related protein).

Ensembl:

ensembl_id ENSDARG00000018383

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00073581 True 2994 mRNA 0.41 7 44832032 44839148

Neighbor


gene id symbol gene type direction distance location
XLOC_037395 nckap1 coding upstream 6613 44721808 ~ 44825419 (+)
XLOC_037393 ppp1r1c coding upstream 342054 44430705 ~ 44489978 (+)
XLOC_037394 NA coding upstream 375924 44455143 ~ 44456108 (+)
XLOC_037392 itprid2 coding upstream 411652 44391254 ~ 44420380 (+)
XLOC_037391 itprid2 coding upstream 462175 44304980 ~ 44369857 (+)
XLOC_037397 BX571855.1 coding downstream 93027 44932175 ~ 44932293 (+)
XLOC_037398 retsatl coding downstream 155066 44994214 ~ 44998722 (+)
XLOC_037399 NA coding downstream 200617 45039765 ~ 45044991 (+)
XLOC_037400 BX510317.1 coding downstream 225007 45064155 ~ 45064269 (+)
XLOC_037401 NA coding downstream 273348 45112496 ~ 45122990 (+)
XLOC_037389 BX649590.1 non-coding upstream 976422 43855495 ~ 43855610 (+)
XLOC_037387 BX470133.1 non-coding upstream 1056667 43775251 ~ 43775365 (+)
XLOC_037386 CU855879.1 non-coding upstream 1500521 43331395 ~ 43331511 (+)
XLOC_037385 NA non-coding upstream 1926410 42732199 ~ 42905622 (+)
XLOC_037403 NA non-coding downstream 422236 45261384 ~ 45261761 (+)

Expression



Co-expression Network


Homologous


species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000009_13942733_13946356 FRZB coding CI01000009 null 13942521 ~ 13946405 (+)
bowfin (Amia calva) AMCG00001071 frzb,LOC106582261,LOC106586471 coding CM030137.1 CM030137.1 13797604 ~ 13802479 (-)