XLOC_037415 (igfbp2b)


Basic Information

Item Value
gene id XLOC_037415
gene name igfbp2b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007120.7
NCBI id CM002893.2
chromosome length 56459846
location 46745348 ~ 46799620 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00073605
ATGTCTCTTGCATTGCTCTGCAGTTTGTTACTGGTGCACGGCTCGCTCGGGGAGATCGTGTTCCGCTGTCCGAGCTGCACCGCGGAGCGCCAGGCAGCGTGTCCCAAGCTCACCACCTCTTGCGAGATTGTCAGAGAACCGGGTTGCGGTTGCTGTCCGGTTTGCGCCCGGCAGAAGGGCGAGCTGTGCGGGGTCTATACGCCGAGATGCGGCAGCGGTTTGAGGTGTTACCCGAGCGCGAATTCAGAGTTACCGCTGGAGCAGCTGATACAAGGACTCGGACGATGCGAGAACAAAGTGGACCTAGAGCCCACCATGACCAACCAGGAGTCAGCAGCACACAGTGGAGAAGTAAATGGCACGCGGTCTCCTCCTATGAAGAAGCCCGGCAAAGACTACCAGTACATCAAGGAAATAGCCGTAAACAAGCATCACAACAACAAGAGGACCAGGATGTACAACACTCAGGATGATCCCAAAACACCTCATCCCAAACAGAGCCAGTGTCAACAGGAGCTGGATAAAGTGTTAGAGAACATCTCCCGAATGGCGTTCCATGACAACAAGGGACCTCTGGAGAATCTTTACGACCTGAAGTTCCCCAACTGTGACAAGACAGGACAGTACAACCTTAAACAGTGCCACATGTCCACCCACGGACAGAGGGGCGAGTGTTGGTGCGTCAACCCTTACACTGGTGTCCAGATACCCTCGTCCGATAAAGTGAGGGGGGACCCCAACTGCAGCCAATACTACGGCGGTCCCGAACTGGAACCACCCACCGCCCAGCAGAAATAGATGCACTCTTGCCCATAAGGGAGACGACCTGGGTGTTAAAGCGAGTGCAAGAGTGATGTGCATGTGTGTTATTCTgtacttgtatgtgtgtgtgtgtaaattttcGAAACAGTGTGATCCTGTATTGTCAGTAGGAGTGTGGAAAGTCACATGCCAGCAAAGACAAGTCAAGGACAGGTATTGTTAAACCTCCCACTTCTCAAATCCAGATATCTGGGCTCCAAATTTAACCCTGAGTGATTGTTATTTCGGCCTATTTATAGGCTTTGTCCGGTGCCTTTTAATCTTGTGACTAAATCTGGTTGCAGGGTGTCGCTTATACAGCATTTGCAGCTGTTCATTGTAAAGATGCGTCCGTTTAATTCTGCCCTTTGTTTTTGGAGACCCAATAAAAAGGGTGGCATGTTTAT

Function

symbol description
igfbp2b Enables insulin-like growth factor I binding activity. Involved in negative regulation of developmental growth. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in gut; kidney; liver; muscle; and ovary. Human ortholog(s) of this gene implicated in obesity. Orthologous to human IGFBP2 (insulin like growth factor binding protein 2).

GO:

id name namespace
GO:0043567 regulation of insulin-like growth factor receptor signaling pathway biological_process
GO:0008156 negative regulation of DNA replication biological_process
GO:0007275 multicellular organism development biological_process
GO:0008285 negative regulation of cell population proliferation biological_process
GO:0040008 regulation of growth biological_process
GO:0048640 negative regulation of developmental growth biological_process
GO:0005576 extracellular region cellular_component
GO:0005615 extracellular space cellular_component
GO:0005520 insulin-like growth factor binding molecular_function
GO:0019838 growth factor binding molecular_function
GO:0031994 insulin-like growth factor I binding molecular_function
GO:0031995 insulin-like growth factor II binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-090107-3 Enables insulin-like growth factor I binding activity. Involved in negative regulation of developmental growth. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in gut; kidney; liver; muscle; and ovary. Human ortholog(s) of this gene implicated in obesity. Orthologous to human IGFBP2 (insulin like growth factor binding protein 2).

Ensembl:

ensembl_id ENSDARG00000031422

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00073605 True 1208 mRNA 0.51 4 46745348 46799620

Neighbor

gene id symbol gene type direction distance location
XLOC_037414 slc4a3 coding upstream 60809 46644633 ~ 46684539 (+)
XLOC_037413 NA coding upstream 129315 46482929 ~ 46616033 (+)
XLOC_037412 NA coding upstream 314052 46415158 ~ 46431296 (+)
XLOC_037411 NA coding upstream 349944 46378709 ~ 46395404 (+)
XLOC_037410 NA coding upstream 861214 45865267 ~ 45884134 (+)
XLOC_037416 NA coding downstream 39026 46838646 ~ 46840389 (+)
XLOC_037417 NA coding downstream 54925 46854545 ~ 47322964 (+)
XLOC_037418 gpbar1 coding downstream 1161862 47961482 ~ 47970760 (+)
XLOC_037419 zgc:92380 coding downstream 1207461 48007081 ~ 48039964 (+)
XLOC_037420 cxcr1 coding downstream 1285419 48085039 ~ 48091741 (+)
XLOC_037408 BX897692.2 non-coding upstream 923763 45821469 ~ 45821585 (+)
XLOC_037425 NA non-coding downstream 1581235 48380855 ~ 48381572 (+)
XLOC_037427 BX927361.2 non-coding downstream 1883155 48682775 ~ 48687885 (+)
XLOC_037428 NA non-coding downstream 1893812 48693432 ~ 48817119 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
eurasian perch (Perca fluviatilis) G80321 txnip,LOC102791564,LOC102307684,LOC101475238,LOC102207340 non-coding NC_053118.1 CM020915.1 41360459 ~ 41362553 (+)