dna2 (dna2)


Basic Information

Item Value
gene id dna2
gene name dna2
gene type coding
species rainbow trout (Oncorhynchus mykiss)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_048587.1
NCBI id CM023241.2
chromosome length 62880378
location 39777382 ~ 39811785 (-)
genome version USDA_OmykA_1.1_2020_rainbow_trout_Genome

Sequence

>XM_021580991.2
TTATGGAGTGGGAGTGTCTTGATTCTAACTACCATGAATGCTTTTAGCGCGAAAAATAAGAAGGAACGCATAGCTGGCAATGAATGAAATAACCTGAAATAGCTGGCTAGCCAAGTCTTTTGACGAGGTTGGCTACCTTTTTATATGTAACCGGTAGGCATTTGAGATGTATGTGTGATTAGTGAAGTAATACGTTTCCAGCTAGGAACTAGCTAACGAAATATGTAAGCTTGCGTTAACTAAAGTAATTTAGCCACTCAGGTTAGCTGCAGCTATCTAAAGCTAGTCATCTAAGTTAGCTATCCTCCAAACACACATGCACGTCGTCAGATCTCTAACGTTACAATGCAGAGGACCAAGTTAAAGAAGAACTCTGTAATTGGAGACCATCAGAAGACACTCTCTTCATTTTTCTACCCAAACAAACTCAAGGAGTCAACGCCTCCCTCAAAGAGAACTATATGCAGCATAACTGAGATGGACTCGTCAAATGTCACCTCTAACCAGCGCAGTGTCCTGGGAGGCATTGAAAATTCTCCCCTGTCTTTTGACCTCTTATCTGTCCCAGAGACCCCCGACAGCCAGATCAGAACCTCTCACCCTGCCAGAAAGCCTGACGATGGGCATCTCTCTCCTATCTGCCGCAGACCGTGCTCCAGAGGGGTCAGCTTAATAAGGGAAAATTCTCCCAAGGCAGCTATGTTCTCCCTGAGGAGTAAGATCAGTCCCCCGCCTCAGGTACAGACGAGCACCAAGAACAGTAACATGCAACGTTGCTCTGTGAAAAGACTGTTCAGTTCCGATGACTTGCAGGTTGCCAAGCGTCCCAAAACCATGCCAGTAAAGAGGCCCTCTATTAGCCCTTTGCGGAAGCCTCTCCTTCATGGAGAGGAATTCCTGAGCGAATGCTTGCAGGTCATTGATGACACTCAAAACTCCAAAGGTACGAAATTCCAGCAGGGCACAGGCCTAGTTGTCAAAGCTGTGAATGGCAGAAAGCCATCCAAGGCTGGTCAGATACACTTAGGTTACAGTGTATTGACATCAGGTGCCAAGGAGAAGATTAGAAACGTCATGCCATCATTAAAGCCACTGTCTGTCAAAAGAGCTTCGTCCTTGTCCTCTAATGAGAGCTCTCTCCCCAGCAGCTTGAGTGAATGTGAAGAGGAGTGTGCTTTTACGGTCATTACAGAACAGAAAGATGCCACAGAATATAATGGCTGCCCTACAGACTTGAATACAAGCGGTGGGCATGTGATAGCAACTAGCTTTGAGAAGCCTAGTAGTGTAAAAACTATCCTTCCGTGTCCACCCAATCCCAATAAGAGCTTAATGGAAGTTGAAAACAGTGCTGTCAGAGACTGTGGCACTGATGGGAAAGGAGTAACATCAGAAGACCACCTGGAGGGGCTGGAGGACAACTGGTTTGATGACAAAATGGAGGAGATCTTCAGTAACACTGAGGAGAAATCCAATGCTGGTAAAAAGAAAGGCATCCCAGACCATGTTATTCTGACCACTGGGCTGCACAACCGCTACTGGATACTAGATGTGCAGGAGATCCATGGTGCTCGTGGCTCTGTGGAGAAACATCTGACCATCACTGCCTCCAAGACCTCCCATCCTACTGAGATTTGTATTCTGAAGGATGGATGGGAGTCGACACCAGTGTCCACGGGTGATGTGGTTCACCTGGAGGGCCAATGTGTCTCAGGTACCTGGCTGATAGACAGGGAGTCAGGATTCTTGGTGCTTCTCCCTGACGTGCTCATATCTGGCACTAGCATCGCCAGCGGGATCCGCTGCATGAGACGGGCCGTGCTGGGGGAGATGTTCAAGTGTTTCGACGGAGGCTCCAAACAGATGTTGAACGGTACGATAGTTCATGACATCTTCCAGAAAGCTGCAATGTCTGGAGACTTCTCTATGGAAAGGCTGCAACTGCTGGCCAACCAAGCCCTGCTCAGCCCCAACTACCTGGGAGACATGTACACCCTGAAACTGACTCAGGAGGACATGAAGCAGGAGATTTGGGAGTACCTGCCAGCAATGACAGAATGGGCCAGAGATTACCTTCACACCTCTCCACAGGCAGGCAAGAAACTGTTAACTCTCAAATTGCCAAGTGATGGGGCACTGAGCTGGCAGGACTCCGCATGCAGCATTGCTGTCACAGATTTTGTGGACATCGAGGAAAACATTTGGTCGCCACGTTTCGGCCTGAAGGGTAAAATTGACGTGACAGCAGGGGTGCGTATTCATCGCAAGGGCAGGCCTCCACTCAACAGGGTAATGCCTTTGGAGCTGAAGACTGGCAAAGAGTCCAACTCCATTGAACACCGCAGCCAGGTCATCCTTTACACTCTGATGAGCTTAGAGAGACGCAGTGATGCAGAGGCAGGATTCCTGCTCTACCTGAAGACTGGCAACCTGCATCCTATAGTCGGGAACCACATGGACAGAAGAGagcTGTTGAAATTAAGGAACACCCTGGCGCATCACGTTGGCAATAGTATGGAGAAGGAAGGCAAGACACGGATGGCACCTCTACCAGGGatcatcacagacagacaggcctgcaAGTGGTGTCCCCAGATCAGGAACTGTGCTCTCTATGACAGgGCCATTGAGAGCAGGGCTCCAGACTACTACTCCAGTGAGTCACAGCAGTTGTTGGTGCAGCAGGAGAGTGAGCACCTGACAGAGGCACACCTGCTCTACTTCAGCCACTGGCTGCTCCTCTGTGCCCTGGAGACCCACACcatggagaggaagggaggcCGGCACAACATCTGGCTGCAGTCTGCCCAAGAGAGGGAGAAGAGTGGGGGGTGTATGGGAAACATGCAGCTGATTGGCCCAGTGAAGAACCAGTCAGACGGTGTGTATATCCACCGTTTTGAGCGCCGTCGTGGTGGGGAACAGGGTGTGACGGGCTTGATTGTTGGCGACAGAGTTGTGGTGAGCGACCATGATTTGCAGCTAATTGGTGTGGCAGCTGGATACGTCACAGACATGAGCAGCACTGCAGTAAGCTGCTCCCTGGATCGGGACCTTTCGAAGTGTTCCTCTGATGTTGTGTTCCGACTGGACCAGGACGAAGGGGTAATGGGATTGAGCACCCATCTGGTCAACCTCTCCAAGATGATGAAAAGGTCTCCTTCAAGTGAAAGACTAAGGGAGCTGATAGTGGATTTCCACCCTCCTCAGTTCATTGACAACCTTAGCAGTGTGTTGCCCAGGGAAGCTAAGGACACAGTCGCCAACATCCTGAAAGGGCTCAACAAACCTCAGAAACAGGCCATGAAGAAGGTTTTGCTCTCCAAAGATTATACGCTCATAGTTGGGATGCCTGGCACTGGGAAAACCACCACTATATGCACACTGGTGCGTATTCTCCATGCATGTGGCTTCAGTGTGCTGCTGACCAGCTACACCCACTCTGCTGTGGACAACATCCTGCTAAAGCTCCGGAGGTTCAAGGTGGGCTTCCTGCGTCTGGGCCGGGCTCAGAAGGTCCACCCAGACATCCTGGCCTACACAGAGGAGAGGTGTCGGACCAACGGCATCCACACACTCCCTGAGCTGGAGAATCTTTACAACAAGGAGCTGGTGGTGGCCACCACGTGCATGGGTGTAAAGCACCCCATTTTCTCCCGTCGTCGTTTTGACTTTTGCATTGTGGACGAGGCGTCCCAGATCAGTCAGCCAGTGTGCCTTGGGCCCCTGTTCTATGCCCAGCGCTTTGTCCTGGTGGGGGACCACCAACAGCTGCCCCCCATTGTCCAGAACAGAGAGGCTAGGTTGTTGGGTATGGACGAGAGTCTATTCAAGCGTCTCGAGCGTAAAAGTGAGGCTGTAGTCCAGCTGAACGTCCAGTACAGGATGAATAGTAAAATCATGTCCCTAAGTAACACTCTGATGTACGGAGGGAGGCTGGAGTGTGGCTCAGAGAGGACTGCCAGCGCCATGCTGACCCTGCCCTCCCAGGGCTCTGTCCAGAGGGAGCTGGAGCTAAGTCTGGGCCGGCCGGAGGACCTGGCTTGGGTCCAGGCAGCTCTGGAGCCTCTCAACCCTGTCTGCTTCCTGGACACCACCCAGGTTCCAGCCCTGGAGACGGTTGACCAGGGGGGAATCAGCAACCAGACAGAAGCTGCTCTGGTGCACGGCATAGTCAGTCTGCTATTGAAGGCTGGGTGCAGGGCCAGTGACATCGGGGTCATTGCTCCCTACAGACAACAACTGAAGGCCATCTCAGGCCTACTAGCCGGGCCAGCCTTCAGCACTGTGGAGGTCAACACTGTGGACAAGTACCAGGGCCGCGACAAGAGCGTCATCATCGTTTCCTTTGTCAGGAGTAACCTAGAAGGCAATCTGGGTGAGCTGCTGAAGGACTGGAGGAGGCTGAACGTGGCCATCACGAGAGCTAAACACAAGCTCCTCATGGTGGGCTCGGCCCCCACCCTGCGCCGCTACGCCCCCCTGGAAAAACTCCTCAACCACCTCACACAGGAGAGCATGGTCTTCCAGCTCCCTCCAGCAGCCCATGAGGTATTACCCACCATGCACCTGTGACGGGACATCTGATGTAGAACATTGCCTTTCCTCCACTCACCATCTGGAAATCAGCCTTTAGACTGATCAAGCAATGTATCGATTCCTCAATATTGATTACTTGAAATAGTTGATAATatgctatatattttttaattcatGTTTTAACAAGAATCCATGGCAGCTATGTTTGTGGTGTTATtgttttaattatttttattaCAACAGAATGTGACCATTCGAAAGTTGAAGTACAGGCACCATTTACACTAAATCTGCTATGTAGCAATTGCTCAGACATTGCCTCACAGACCTCCGTTAGATTAAGATTGGTCATTAGTCTTGTTTCTGAGCCAGTGCTGATTGTCGAGCTTTTACTTGTTATATTGACGTTCATTTTGAAAATTTCTATGTGAATAAATCATTTTAAGTGTTGTA

Function

symbol description
dna2 Predicted to enable 5'-flap endonuclease activity; RNA binding activity; and site-specific endodeoxyribonuclease activity, specific for altered base. Predicted to be involved in DNA metabolic process; mitochondrial DNA replication; and positive regulation of DNA replication. Predicted to act upstream of or within DNA repair and DNA replication, Okazaki fragment processing. Predicted to be located in mitochondrion and nucleus. Predicted to be active in cytoplasm. Is expressed in ovary. Human ortholog(s) of this gene implicated in Seckel syndrome 8; autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 6; isolated growth hormone deficiency type IA; and mitochondrial myopathy. Orthologous to human DNA2 (DNA replication helicase/nuclease 2).

NR:

description
DNA replication ATP-dependent helicase/nuclease DNA2

GO: NA

KEGG:

id description
K10742 DNA2; DNA replication ATP-dependent helicase Dna2

RNA

RNA id representative length rna type GC content exon number start site end site
XM_021580991.2 True 4992 mRNA 0.51 23 39777382 39811785

Neighbor

gene id symbol gene type direction distance location
hnrnph3 hnrh3 coding downstream 4782 39766791 ~ 39772600 (-)
tacr2 LOC106612452 coding downstream 111356 39660915 ~ 39666026 (-)
irf1a LOC106612476 coding downstream 259619 39514302 ~ 39517763 (-)
LOC110502717 LOC106612488 coding downstream 303749 39457772 ~ 39473633 (-)
myom2b LOC106612511 coding downstream 393218 39359063 ~ 39384164 (-)
LOC110502743 LOC106612385 coding upstream 135699 39947484 ~ 39958097 (-)
LOC110502744 LOC106612365 coding upstream 196598 40008383 ~ 40072508 (-)
sfxn2 sfxn2 coding upstream 284311 40096096 ~ 40102224 (-)
trim8b trim8 coding upstream 324037 40135822 ~ 40143175 (-)
LOC110502750 LOC106612307 coding upstream 343220 40155005 ~ 40177932 (-)
G1864211 NA non-coding downstream 60804 39714695 ~ 39716578 (-)
G1864139 NA non-coding downstream 156290 39620849 ~ 39621092 (-)
G1864138 NA non-coding downstream 156921 39620231 ~ 39620461 (-)
G1864136 NA non-coding downstream 157863 39619234 ~ 39619519 (-)
G1864135 NA non-coding downstream 162006 39615092 ~ 39615376 (-)
G1865201 NA non-coding upstream 230776 40042561 ~ 40042776 (-)
G1865202 NA non-coding upstream 231018 40042803 ~ 40043042 (-)
G1865206 NA non-coding upstream 236487 40048272 ~ 40049044 (-)
G1865210 NA non-coding upstream 243406 40055191 ~ 40055420 (-)
G1865214 NA non-coding upstream 249185 40060970 ~ 40061456 (-)
G1864033 NA other downstream 323967 39449397 ~ 39453415 (-)
G1862272 NA other downstream 1620173 38156749 ~ 38157209 (-)
G1861368 NA other downstream 2441968 37335027 ~ 37335414 (-)
G1860462 NA other downstream 3325923 36448831 ~ 36451459 (-)
LOC110502661 golga7b other downstream 3818177 35954220 ~ 36014458 (-)
srsf2a LOC106612293 other upstream 368044 40179809 ~ 40185223 (-)
G1868010 NA other upstream 3103621 42915406 ~ 42978144 (-)
G1868940 LOC106611807 other upstream 3675083 43486868 ~ 43501433 (-)
G1872165 NA other upstream 6216135 46027920 ~ 46029807 (-)
G1872556 NA other upstream 6985450 46797235 ~ 46797650 (-)

Expression


Co-expression Network