XLOC_037904 (otc)



Basic Information


Item Value
gene id XLOC_037904
gene name otc
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007120.7
NCBI id CM002893.2
chromosome length 56459846
location 30268040 ~ 30274412 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00074421
CCGTCTAGTACTGTATGACAGGGAGCGCGTGGACATCCTCTGACTTGGCAGTGTTGCAGTGTACaactttaaatgtgtttatgCATATGTTGTAAAAATGTTTGCTCTCAAAAGTAGAATATATTACAGCCTGGGGTTTGCAAAGTGTTGCCAAAGCAGGAATTTTAGTGTGGGAAAAGCAACTTTGGACAGTGTCAACCTGAAGGGTCGCAGCTTTCTAACACTTAAAGACTATAATGCTGAAGAAATTAAACATATCCTGTGGGTTTCCGCTGACCTAAAACATCGAATAAAGCACAGAGGAGAGCATCTCCCATTACTTCAAGGCAAATCTATTGCCATGATATTTGAGAAGAGGAGCACTAGGACCCGCATGTCCACTGAAACAGGATTCTCTCTGTTGGGTGGTCATCCATGTTTCCTCACGCCTCAGGATATTCATCTAGGGGTCAATGAATGCACCACAGACACGGCCAGGGTTCTTTCAGGTTTGGCAGACATCGTGTTGGCTCGGGTGTATAATCACTCGTCTCTGGAGCACCTGgataaagacacttctataccagTAATCAATGGTCTCTCTGACCTTTACCACCCTATTCAGATTCTGGCTGACCTGCTAACACTACAGGAACACTATGGCTCATTAAAAGGCCGTACATTGACTTGGATAGGAGATGGAAACAATGTTCTTCACTCTTTCATGATGTCATTGGCTAAACTAGGTGTCAATCTGAAAGTGGCCACACCCAAGGGTTATGAGCCAGATGCTGCTGTCACTGAAGAGGCTCAGCGTCTGGCAAAGCAGTTTGGTACCAGACTGCAGTTTGTGTCAGATCCAGTGGAGGCAGCGCGGGACAGCAGTGTTCTGGTAACTGACACCTGGGTGAGCATGGGCCaagaggaggagaagaagaagagaCTAAAAGATTTCAGTGGCTACCAGATCACCATTCAGACAGGAAGCGTGGCTGCACCTGACTGGACATTTCTGCATTGTCTTCCACGTAAACCAGAGGAAGTGGACGATGAAGTTTTCTACTCACAACGTTCACTTGTTTTCGAAGAGGCCGAGAACCGCAAGTGGACCATTATGGGTTTAATGGTGTGCATCCTGACAGACTATAGGCCACAAATTCCCACACTCAAATTGTAAAAAATGTGTGGGAAAATAAATCCTAAGAACAAAATAAGGTAATAAATGCATctgttttttgtcaaataaaacgAGTAACCTGC
>TCONS_00074422
aaaaaaattgtttttactctctggtagtcaaaacatattcaaaagaaatttctatgttaaatatgcattacaaaaccGTCGGGAAAAAGTGTTCTATGTAAATTCGAACCACGAGTCCACATAcatggacataatttttctctaaaagtacatcaaatcaaaagatgatacttgggtttttattctaattaggttccaataagcccaaatagcaaagaggaATAAAATATGCCTGTagaaaaacaccttgggccttaagaggttaaacaGAAACGTTCCATAGCTCATGATTTACTGCTTTGTGTTTTTTCCTTTACACTTTCAAATTGTGTTATGGGACCTTTAACTCTGCTCTgaccatttttttaatgttaaaaagctTAAACAACTAACTATTATGGATATGTTCAGTAGTTTAAAAATTCTACATTGTCTGGATTCTAGTCATGTTAAATAGCCTACAAGGTAATGACCACAATTTTACactattttacagatttatttcttaGAGTAGACTCAATACAGTGATGCTTTCACATGGGGTGTATGTGTGGCAGGGTTCTTTCAGGTTTGGCAGACATCGTGTTGGCTCGGGTGTATAATCACTCGTCTCTGGAGCACCTGgataaagacacttctataccagTAATCAATGGTCTCTCTGACCTTTACCACCCTATTCAGATTCTGGCTGACCTGCTAACACTACAGGAACACTATGGCTCATTAAAAGGCCGTACATTGACTTGGATA

Function


symbol description
otc Predicted to enable ornithine carbamoyltransferase activity. Predicted to be involved in arginine biosynthetic process via ornithine and citrulline biosynthetic process. Predicted to act upstream of or within cellular amino acid metabolic process and urea cycle. Predicted to be active in mitochondrion. Is expressed in ball; brain; liver; and muscle. Human ortholog(s) of this gene implicated in ornithine carbamoyltransferase deficiency. Orthologous to human OTC (ornithine transcarbamylase).

GO:

id name namespace
GO:0019240 citrulline biosynthetic process biological_process
GO:0042450 arginine biosynthetic process via ornithine biological_process
GO:0006520 cellular amino acid metabolic process biological_process
GO:0043231 intracellular membrane-bounded organelle cellular_component
GO:0005739 mitochondrion cellular_component
GO:0016740 transferase activity molecular_function
GO:0016743 carboxyl- or carbamoyltransferase activity molecular_function
GO:0004585 ornithine carbamoyltransferase activity molecular_function
GO:0016597 amino acid binding molecular_function

KEGG:

id description
ko00220 Arginine biosynthesis

ZFIN:

id description
ZDB-GENE-070912-422 Predicted to enable ornithine carbamoyltransferase activity. Predicted to be involved in arginine biosynthetic process via ornithine and citrulline biosynthetic process. Predicted to act upstream of or within cellular amino acid metabolic process and urea cycle. Predicted to be active in mitochondrion. Is expressed in ball; brain; liver; and muscle. Human ortholog(s) of this gene implicated in ornithine carbamoyltransferase deficiency. Orthologous to human OTC (ornithine transcarbamylase).

Ensembl:

ensembl_id ENSDARG00000062147

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00074421 False 1239 mRNA 0.45 10 30268040 30274412
TCONS_00074422 True 753 lncRNA 0.35 2 30271025 30271850

Neighbor


gene id symbol gene type direction distance location
XLOC_037903 mid1ip1a coding downstream 3625 30263188 ~ 30264415 (-)
XLOC_037902 si:dkey-100n23.5 coding downstream 8528 30248571 ~ 30259512 (-)
XLOC_037901 SENP7 coding downstream 20006 30217828 ~ 30248034 (-)
XLOC_037900 impg2a coding downstream 77527 30188764 ~ 30190513 (-)
XLOC_037899 abi3bpa coding downstream 102419 30132498 ~ 30165621 (-)
XLOC_037905 BX571713.1 coding upstream 22263 30296675 ~ 30296791 (-)
XLOC_037906 sytl5 coding upstream 49050 30323462 ~ 30363770 (-)
XLOC_037907 asb11 coding upstream 90255 30364667 ~ 30371247 (-)
XLOC_037908 piga coding upstream 99769 30374181 ~ 30385278 (-)
XLOC_037909 gja8a coding upstream 155776 30430188 ~ 30432778 (-)
XLOC_037898 BX322575.1 non-coding downstream 160080 30104920 ~ 30107960 (-)
XLOC_037896 CR749776.1 non-coding downstream 459976 29807947 ~ 29808064 (-)
XLOC_037894 NA non-coding downstream 560783 29682197 ~ 29707257 (-)
XLOC_037893 NA non-coding downstream 605415 29652041 ~ 29662625 (-)
XLOC_037889 NA non-coding downstream 758065 29506420 ~ 29509975 (-)
XLOC_037910 NA non-coding upstream 184292 30458704 ~ 30474478 (-)
XLOC_037911 NA non-coding upstream 216093 30490505 ~ 30503378 (-)
XLOC_037912 NA non-coding upstream 243505 30517917 ~ 30525279 (-)
XLOC_037915 BX571809.1 non-coding upstream 403058 30677470 ~ 30680018 (-)

Expression



Co-expression Network