XLOC_000038 (atp1a1a.5)



Basic Information


Item Value
gene id XLOC_000038
gene name atp1a1a.5
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007112.7
NCBI id CM002885.2
chromosome length 59578282
location 1838164 ~ 1850104 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00000075
TGTCTCCAATCAGCTCCAGCACAGGAGGACTATCCTGACTCCTCAAATCGCTGCATTTTGGATGGGAAATGGGGCTTCTGACAGGGAAAGATGACTATAAAGTGGCGGCGACTTCAGAAGATGGAGTCAAAACGcctaaaaaagggaaaaagaacAAAAAGGACATGGACGAACTGAAGAAAGAAGTGGAAATGGATGATCACAAACTAACAATGGAGGAGCTGAGCAGAAAATATGGCACTGATCTGACAAAGGGCTTGCCTGTTTCTCGAGCGATGGAAGTCTTAATGCGTGATGGACCAAACGCCCTGACTCCACCGGTTATAACTCCAGAATGGGTGAGGTTCTGCCGGCAACTCTTTGGTGGATTTCAGACTCTGCTGTGGATCGGTGCATTTCTCTGCTACTTTGCATTTTCGATCCAGGCTGCAACGGAAGAGCCAGTAAATGACAATCTGTATCTAGGAATTGTGCTTACCTTTGTGGTCACAGTCAATGGATGCTTCTCATACTCTCAAGAGGCAAAGAGCTGTAGAATCATGGATTCCTTCAAGAACCTCGTTCCTCAGAAAGCCCTGGTTGTGCGTGATGGAGAGAAAAAGATCATTGATGCTGAAGAGGTAGTTGTGGGTGATCTTGTTGAGGTCAAAGGTGGAGACAAAATCCCAGCTGATATTCGCATCGTATCTTCACATGGATGCAagGTGGACAACTCTTCCCTGACTGGAGAATCTGAGCCCCAGATTCGCACTGCAGACATGTCTAGTGAAAACCCACTGGAGACAAGAAACATCGCATTTTTTTCTACCAACTGTATTGATGGTGCTGCCAGAGGGATTGTTGTCAACACCGGTGACCGCACTGTCATGGGTCGCATTGCATCACTTGCCTCCAACCTGGAAGGTGGACAAACACCACTTGGCCGAGAAATCGAGCACTTCATCCACATCATCACCGGTGTAGCTGTTTTCTTGGGCACGACCTTCTTAATTATCTCCGTGATGCTTGGCTTTACTTGGCTAGAGGGCATCATTTTTCTTATTGGGCTCATTGTCGCTAATGTACCTGAAGGTCTCCCTTGCACTGTAACTGTGGCTCTGACTCTCACTGCCAAACATATGGCAAAGAAAAACTGCCTGGTGAAGAATCTTGAAGCTGTGGAGACTCTTGGTTCAACCTCCACCATTTGCTCGGACAAAACTGGAACTTTGACCCAGAACCGGATGACTGTCGCTCACATGTGGTTCGACAACCAGATTCATATAGCCGATACCACAGAGAACCAGACTGGAGCCTCATTTGACAGGAGCTCAGCTACTTGGTCTGCTCTCGCACGTGTTGCTGGCCTTTGCAATCGTGCTGTCTTCCAGTCAAATCAGAGTCATCTTCCAGTGCTTAGGAGAGAGACAGCTGGTGATGCCTCAGAGTCTGCACTGCTGAAGTGTATTGAGCTGTGCTGCGGTTCAGTCACTGAAATGAGAGAAAACTACCCAAAGGTTGCTGAGATCCCGTTCAACTCCATTAGCAAGTATCAGCTCTCAATCCATGAGAATCCCAATTCCTCAGAGCCAAAACACCTCCTGGTGATGAAGGGAGCACCTGAGAGAATCTTGGATCGGTGTTCGACCATTTTAATTGAAGGAAAAGAGCATCCTTTAGATGATGAAATGAAAGAGGACTTTCAGAATGCTTATGTTCAACTTGGAGGTCTTGGAGAAAGAGTCCTGGGTTTCTGCCACTTTGGCCTTCCTGATGATCAGTTTCCTGAGGGTTTTGCATTTGATACTGAAGAAATGAACTTCCCCACTGAGAACCTGTGCTTTGTTGGCCTCATGTCCATGATTGATCCTCCTCGTGCCGCTGTACCAGATGCTGTGGCCAAATGCCGGAGTGCTGGAATCAAGGTAATCATGGTTACTGGTGACCATCCGATCACAGCAAAGGCTATTGCAAAAGGTGTCGGCATCATCTCAGAAGGCAATGAGACAGTGGATGACATCGCTGCTCGGCTGAAAATCCATATTGATGAGGTGAATCCAAGAGATGCTAAGGCCTGCGTGATCCATGGAGGAGAACTGAAAAATATGACAGATGAACAGCTGGATGACGTCCTTCAACATCATACAGAAATTGTGTTCGCCAGAACGTCTCCACAACAAAAGCTGATCATTGTGGAAGGATGTCAGCGACAGGGTGCCATTGTAGCCGTAACCGGTGATGGAGTCAATGATTCTCCAGCTCTGAAGAAGGCTGACATTGGTGTGGCTATGGGTATTGCTGGATCTGACGTATCCAAACAGGCTGCTGACATGATCCTTCTGGACGACAACTTTGCCTCAATTGTCACTGGAGTAGAAGAAGGCCGTCTGATCTTTGACAACTTGAAGAAGTCCATTTGCTACACACTGAGCACCAAGATCCCGGAGATGTCACCCTTCCTCATGTTTGTCCTCGCTGGTATTCCTCTACCTCTGGGCACCGTCACCATTCTCTGCATTGACCTGGGCACTGACATGGTTCCTGCTATCTCCTTTGCCTATGAAAATGCAGAAAGTGACATCATGAAGAGACAACCCAGAAATGCTGCAACTGATAGGCTGGTGAACGAGAGGCTGGTCAGTGTGAGCTATGGTCAAATTGGTGTGATGAATGCATTTGGCGGGTTCTTTACCTACTTTGTGATTCTTGCTGAGAATGGCTTCTTGCCTTGGGATCTGGTGGGATTACGGATTGGCTGGAATGACAGATATTTCAGTGAAGTGGAAGACAGCTATGGCCAGCAATGGACCTACGAGCAGAGGAAGGTTCTGGAGTACACATGCCACACCGCCTACTTTACCAGCATTGTGATCATGCAGTGGACTACTTTGCTTGTTTGCAAGTCCAGAAGGCTTTCCCTTGCAAAGCAGGGAATGAAAAACCGAGTCCTCACTTTTAGTCTGTTTGAGGAAACTGCAATTGCAGCGTTCCTGTCTTACTGCCCAGGCATGGACATTGCAGTCAGAATGTATCCATTGAAACCTATGTGGTGGTTCTGTGCCTTCCCATATATGATCCTCATTTTCATCTATGATGAAGTTAGAAAACATTTCATTAGGCAAAACCCAGGAGGCTGGGTGGAACAAGAAACATACTACTAAAGCCAGAAGACTTTCTGTTGAACATGAGCAAGGAGAGATTGCATCCTTTGGAAAACATCAAAATGAACACCCGTTTAGGTTATTAAATACGTCAGATTACAGGgatattcacccaaaaatgaacattctgccatcatttactaaccctttcacatttctttattctatttaacacaaaagaagatgttttgtaagctgaaaccattgacttcttttATTtatactatgggagtcaatggttatgTTTTCAGCTTACTTTGTAATATCTACTGTGTTCAACAGGATTAAGAAACGTAAAGGTTTAGATTAaagtgagggtgagtaaattaacattttaaggaGAACGATCCATTTATAAACAAGAAGCATCCAAGTCATTTGCACACATGCATGCGTAGTTGCTCAGCTTATTATAATAGATTCATTTACATTGAGTGTATTTATGAAAATCCACATtcatggcatttaaaaaaaatataggtTTCAACCAAGCTGCTAACAAGTTTTAGTTTTAACCTTTAGCACTGTATTTAGCAGTGTATTTCACTATAATCAAACATTACTCTTTTGTTTTTCATGCAATAAAATCCACATGTTGGATTAACGTGAGGTTATGTACAGAACAGAGTACACTGTATTGATGAACAATAAagacacaataaaacaaaaacacaataaaa

Function


symbol description
atp1a1a.5 Predicted to enable P-type sodium:potassium-exchanging transporter activity. Predicted to be involved in cellular monovalent inorganic cation homeostasis and inorganic cation transmembrane transport. Predicted to act upstream of or within potassium ion transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including immature eye; mucus secreting cell; nervous system; otic vesicle; and pronephros. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2DD. Orthologous to human ATP1A1 (ATPase Na+/K+ transporting subunit alpha 1).

GO:

id name namespace
GO:0006883 cellular sodium ion homeostasis biological_process
GO:1902600 proton transmembrane transport biological_process
GO:0036376 sodium ion export across plasma membrane biological_process
GO:0030007 cellular potassium ion homeostasis biological_process
GO:0006811 ion transport biological_process
GO:0006813 potassium ion transport biological_process
GO:1990573 potassium ion import across plasma membrane biological_process
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0005391 sodium molecular_function
GO:0005524 ATP binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0008556 potassium transmembrane transporter activity, phosphorylative mechanism molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-020501-1 Predicted to enable P-type sodium:potassium-exchanging transporter activity. Predicted to be involved in cellular monovalent inorganic cation homeostasis and inorganic cation transmembrane transport. Predicted to act upstream of or within potassium ion transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including immature eye; mucus secreting cell; nervous system; otic vesicle; and pronephros. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2DD. Orthologous to human ATP1A1 (ATPase Na+/K+ transporting subunit alpha 1).

Ensembl:

ensembl_id ENSDARG00000040252

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00000075 True 3820 mRNA 0.44 22 1838164 1850104

Neighbor


gene id symbol gene type direction distance location
XLOC_000037 atp1a1a.3 coding upstream 22504 1805294 ~ 1815660 (+)
XLOC_000036 atp1a1a.1 coding upstream 41332 1712140 ~ 1796832 (+)
XLOC_000035 atp1a1a.4 coding upstream 132005 1689775 ~ 1706159 (+)
XLOC_000034 NA coding upstream 218850 1617203 ~ 1619314 (+)
XLOC_000033 urp2 coding upstream 223664 1599979 ~ 1614500 (+)
XLOC_000039 si:ch211-132g1.6 coding downstream 46633 1896737 ~ 1899848 (+)
XLOC_000040 si:ch211-132g1.4 coding downstream 54315 1904419 ~ 1911381 (+)
XLOC_000041 si:ch211-132g1.1 coding downstream 65863 1915967 ~ 1923253 (+)
XLOC_000042 si:ch211-132g1.7 coding downstream 90927 1941031 ~ 2000357 (+)
XLOC_000043 NA coding downstream 151612 2001716 ~ 2005632 (+)
XLOC_000032 NA non-coding upstream 259913 1571847 ~ 1578251 (+)
XLOC_000031 NA non-coding upstream 477333 1358731 ~ 1360831 (+)
XLOC_000030 NA non-coding upstream 495927 1315289 ~ 1342237 (+)
XLOC_000029 CR450787.2 non-coding upstream 619359 1218691 ~ 1218805 (+)
XLOC_000044 NA non-coding downstream 173305 2023409 ~ 2023645 (+)
XLOC_000049 CR352215.1 non-coding downstream 425501 2275605 ~ 2275742 (+)
XLOC_000051 CR352215.2 non-coding downstream 552999 2403103 ~ 2403224 (+)
XLOC_000053 NA non-coding downstream 1868562 3718666 ~ 3720603 (+)

Expression



Co-expression Network