XLOC_003963 (cdc6)


Basic Information

Item Value
gene id XLOC_003963
gene name cdc6
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007122.7
NCBI id CM002895.2
chromosome length 45484837
location 11781973 ~ 11792766 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00007575
ATTTGCTTCctggttttaaacataaaaatgccCAGCACTCGCTCACAGAATCAGCCAACTCTACAGTTCCCTAGAAGGAAGTCTTCCAGATTGGGGTCTCGGCCTAAAAGCTCCTGCGAAAATAAAGTGGACGATAAGACCACCCCTTTGTCCCCTAGAAAGGCAATTGTGGGAAATTCACTCGGTGTTTGTCAATCTCCCAGGAACAAGGTGTTAAACTCCCCTTTGTCTGAAAGGCTGCCTCTGAGCCCCCGCAAACGCACAGgtgaTGAGAATGGCTGTAACCTGCCAGCCTCCATGCTTGGCTCTCCCCCTAAGCAGCGCTGCGCTCCTCTGTGCTCCCCTCGCAAGCTGTCCTTCAACGAGAACACACCAGTCCTCTCCTCACCTCCCCGTCCTATCCTGTCCTCGCACAAAGTTCCTCTGTCTCCCATTTCTCGTCCATCGCCAACACGACTGAACGAGACATCATGCACCAACATAATCCCCCGTACAGAGGGAAGGAGCCCTGTTACGCGACTGTTTCCTATAAAGAAATCCGGTTTTCAGAGTGTAAAGCAGGCTCTTCACACTGCAGTACCTGAACGTCTCCTCTCTCGTGAGGCAGAGAGAGCTGCCATTGTCTCCTTCCTGCAAAATCACGTAGTGGCAGAAAAACCCTCCAGCCTTTACATCTCTGGTGCTCCTGGCACAGGCAAGACGGCTTGTCTGAACTGTGTGCTCCAAGAACAAAAGGCTCTGTTAAAAGGCATCCAGACTGTGGTCATCAACTGTATGAATTTGCGGAGCTCTCATGCCATCTTTCCATTGCTGGGAGAGCAACTGGAGGTTCCCAAAGGCAACAGTCAGGCACGATTGGAGAAGTATTTGACCAGCTCTGGACCCACTGTCTTGTTGGTTCTTGATGAGATGGACCAGTTGGACAGCAAGTCTCAAGAAGTTCTCTACACCATTTTTGAGTGGCCTTACTTGCCCAAATCTCGTGTTTGTCTCATCGGTATTGCTAATGCACTGGACTTGACTGATCGTATCCTGCCAAGACTGCAGGCGAAACCACACTGTCGTCCCAAACTGCTCAACTTTCCTCCCTACAGTCATGAAGAGCTCAATGCTATTGTACAGGACAGACTCACACAGGTATCAGGTGAAGGGGTTTTGGATGCAGCGGCAGTTCAGTTTTGTGCAAGGAAAGTCTCCGCTGTGTCAGGAGATGCTCGCAAAGCACTGGACATCTGCAGGAGGGCTGTGGAGATTGTGGAAGCAGGCGACAGGTCTAAAATGGCATCCGAACCTACAGCCAGCTCTAAAGTGTCGAGAGTGAGTGTTCCTCAAGTGGCTCGGGTTTTGTCAGAGGTTTATGGTGACCGTATGGCATCCAGTAGTGGAGATGGCGAGAGCTTTCCTTTACAGCAGAAACTTCTGGTCTGCTGCCTGCTTTTGATCATCCGCAACGGCAAAAGTAAAGAGACCCAGTTGGGCAAGCTGTGTGAAGTGTACAGTAAGCTGTGTAAGCAGAGGCAGGTTGGTGGAGTCGGCCAGACGGagtgtctctctctctgcagCCTGTTGGAGAGCAGGGGAATCCTCACTCTCAAAAAGGCCAAGGACGCTCGACTGACTAAAATCTCCTTGAAGATTGAAGAGCGAGATGTGGAGCATGCTTTAAAGGATCGAACTCTCCTTGGAAGCATATTAGCGGCTGGTTTGCCGTAATCCACATAagattttaacctttttttttttaatgattttatgttttcttcattcctctaaatgttttatttcttgaCTGTGAAGGTCTCGTTTTAAAATGAGATATTTTATTGCAGAGAGGGATGATCTGATCCAAAAGGGTTAACGTCACTTTATTATGTTTGTGTCAAACATTTTTACCTGCCTTTCTAAATGTAGGGCCGTTTTATGTTTTCTTTCAGGTTTCTAAATGTTTATGAATCCATATTTCATGTTTAACAGTTGACATTGGCTGCTATTACATTTTGTACATcagttttgtaatgtttttgaatGGGTGTACTCTTTTAATAAAGCAGAATGTACATGAGTTTGATCCTGAGTCTGATTTGAGTAATTTATTATCTTTAAAGTTGAAAGGCTTGTAAAAATGACTATTTTCATGACTGTTTGTGACCCCTGAAGAATTCAAATGGCTAAAGTCTATGGTGGATATACTATTAGCATCAGTCTCGGGTGTAATGACATTACATTACTTCTCCAAAAAAATGAGGGGATTgcttttaatttgtcatttagtCTAGGTACAGTTCCTTACAATGTACTTGACTTttcaaatactgtaaataaattgaaCGATTCAGAGATgtcaaacaaaaccaaaaagaaCTTGGTTATACAAATATTTCTGCTTCAACTAAAGGTTACATGtgtaaatttgaataaaaacaagtaagAAATTGACTGTGACAATATTGTCTACTTTAAAAGtgttggtgtttaaaaaaaaaaattcctttttaGAGAGGAGTTTAATTTCTGTTGTCAACAAGATTTATAGGGATTTTTAGTATTCAGTCAATTACTTTAGGAAAGAAATAGAATAGTAATTTAAATccaattttaattatgtaattagtaaATATTTACTTTCATAAAGTAACATACCCAACGCTGATACTGGTACAGCTTGTCTATAATAATTTACACATCCATTCCCCAACAATAAggcacatggcagcaactcaatgcatttaggcatgtagacatgggcaagatgatctgctgcagttcaaacagcatcagaatgggcaagAGAGGTGAtttaaagtgactttaaacgtggcagggttttggtgccagacaggctggtctaagtatttcagaaactgctgatctgagattttcacgcacaaccatctctagggtttacagagaatgtacGAAAAAGAGGaaatgtccagtgagcggcagttgtgtcagctaagaacaggaaactaaggctacaattcgcagAGGCTCAACAATTTTGGACAATAGacgattggaaaaacgttgcccgGTCTTAAATTCAGCTGTGACATTCGCTCAGAAATTGGCGTCAACATCATAGATGGGCAGCCTTCAGCAactgtgatgccatcatgtcaatatggacaaaaatctctgaggaatatttccagtatcttgttgaatctatagcacgaaggattaaggtagttctgtaGTCGAAAGGGGGTCTAACTCcttactaataaggtgtacctaataaagtgaccggttagtgtgtatgtgtgtgtgtatatatatatatatacatatacatatacatatatatatatatacatatacatatatatatacatatacacatatatatatatatatatacatatacatatatatatatacatatacatatatatatatacatatatatatatatacatatacatatatatatatatacatatacatatatatatatatatacatatacatatatatatatatacatatacatatatatatatatacatatacatatatatatatacatatacatatacatacatatacatataca
>TCONS_00007576
ACATACCAACGCACCAGCTGATCCGAGAAGGAGTTCACAACATCACATTTGGCGCTAGTTTGACGGCGGAGGAAGTCGGTTTCAGGAGCAGAGAAACTACAGCTTTTGATTATAGCACACACAGTCAACAAATTCAACTATTTAAAGATTTGCTTCctggttttaaacataaaaatgccCAGCACTCGCTCACAGAATCAGCCAACTCTACAGTTCCCTAGAAGGAAGTCTTCCAGATTGGGGTCTCGGCCTAAAAGCTCCTGCGAAAATAAAGTGGACGATAAGACCACCCCTTTGTCCCCTAGAAAGGCAATTGTGGGAAATTCACTCGGTGTTTGTCAATCTCCCAGGAACAAGGTGTTAAACTCCCCTTTGTCTGAAAGGCTGCCTCTGAGCCCCCGCAAACGCACAGgtgaTGAGAATGGCTGTAACCTGCCAGCCTCCATGCTTGGCTCTCCCCCTAAGCAGCGCTGCGCTCCTCTGTGCTCCCCTCGCAAGCTGTCCTTCAACGAGAACACACCAGTCCTCTCCTCACCTCCCCGTCCTATCCTGTCCTCGCACAAAGTTCCTCTGTCTCCCATTTCTCGTCCATCGCCAACACGACTGAACGAGACATCATGCACCAACATAATCCCCCGTACAGAGGGAAGGAGCCCTGTTACGCGACTGTTTCCTATAAAGAAATCCGGTTTTCAGAGTGTAAAGCAGGCTCTTCACACTGCAGTACCTGAACGTCTCCTCTCTCGTGAGGCAGAGAGAGCTGCCATTGTCTCCTTCCTGCAAAATCACGTAGTGGCAGAAAAACCCTCCAGCCTTTACATCTCTGGTGCTCCTGGCACAGGCAAGACGGCTTGTCTGAACTGTGTGCTCCAAGAACAAAAGGCTCTGTTAAAAGGCATCCAGACTGTGGTCATCAACTGTATGAATTTGCGGAGCTCTCATGCCATCTTTCCATTGCTGGGAGAGCAACTGGAGGTTCCCAAAGGCAACAGTCAGGCACGATTGGAGAAGTATTTGACCAGCTCTGGACCCACTGTCTTGTTGGTTCTTGATGAGATGGACCAGTTGGACAGCAAGTCTCAAGAAGTTCTCTACACCATTTTTGAGTGGCCTTACTTGCCCAAATCTCGTGTTTGTCTCATCGGTATTGCTAATGCACTGGACTTGACTGATCGTATCCTGCCAAGACTGCAGGCGAAACCACACTGTCGTCCCAAACTGCTCAACTTTCCTCCCTACAGTCATGAAGAGCTCAATGCTATTGTACAGGACAGACTCACACAGGTATCAGGTGAAGGGGTTTTGGATGCAGCGGCAGTTCAGTTTTGTGCAAGGAAAGTCTCCGCTGTGTCAGGAGATGCTCGCAAAGCACTGGACATCTGCAGGAGGGCTGTGGAGATTGTGGAAGCAGGCGACAGGTCTAAAATGGCATCCGAACCTACAGCCAGCTCTAAAGTGTCGAGAGTGAGTGTTCCTCAAGTGGCTCGGGTTTTGTCAGAGGTTTATGGTGACCGTATGGCATCCAGTAGTGGAGATGGCGAGAGCTTTCCTTTACAGCAGAAACTTCTGGTCTGCTGCCTGCTTTTGATCATCCGCAACGGCAAAAGTAAAGAGACCCAGTTGGGCAAGCTGTGTGAAGTGTACAGTAAGCTGTGTAAGCAGAGGCAGGTTGGTGGAGTCGGCCAGACGGagtgtctctctctctgcagCCTGTTGGAGAGCAGGGGAATCCTCACTCTCAAAAAGGCCAAGGACGCTCGACTGACTAAAATCTCCTTGAAGATTGAAGAGCGAGATGTGGAGCATGCTTTAAAGGATCGAACTCTCCTTGGAAGCATATTAGCGGCTGGTTTGCCGTAATCCACATAagattttaacctttttttttttaatgattttatgttttcttcattcctctaaatgttttatttcttgaCTGTGAAGGTCTCGTTTTAAAATGAGATATTTTATTGCAGAGAGGGATGATCTGATCCAAAAGGGTTAACGTCACTTTATTATGTTTGTGTCAAACATTTTTACCTGCCTTTCTAAATGTAGGGCCGTTTTATGTTTTCTTTCAGGTTTCTAAATGTTTATGAATCCATATTTCATGTTTAACAGTTGACATTGGCTGCTATTACATTTTGTACATcagttttgtaatgtttttgaatGGGTGTACTCTTTTAATAAAGCAGAATGTACATGAGTTTGA

Function

symbol description
cdc6 Predicted to enable DNA replication origin binding activity. Acts upstream of or within mitotic cell cycle phase transition. Predicted to be active in nucleus. Is expressed in central nervous system and proliferative region. Used to study Meier-Gorlin syndrome. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 5. Orthologous to human CDC6 (cell division cycle 6).

GO:

id name namespace
GO:0044772 mitotic cell cycle phase transition biological_process
GO:0051301 cell division biological_process
GO:0033314 mitotic DNA replication checkpoint biological_process
GO:0006270 DNA replication initiation biological_process
GO:0000278 mitotic cell cycle biological_process
GO:0005634 nucleus cellular_component
GO:0005524 ATP binding molecular_function
GO:0003688 DNA replication origin binding molecular_function

KEGG:

id description
ko04110 Cell cycle
ko04111 Cell cycle - yeast
ko04113 Meiosis - yeast
ko05207 Chemical carcinogenesis - receptor activation
ko03032 DNA replication proteins

ZFIN:

id description
ZDB-GENE-050506-131 Predicted to enable DNA replication origin binding activity. Acts upstream of or within mitotic cell cycle phase transition. Predicted to be active in nucleus. Is expressed in central nervous system and proliferative region. Used to study Meier-Gorlin syndrome. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 5. Orthologous to human CDC6 (cell division cycle 6).

Ensembl:

ensembl_id ENSDARG00000009942

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00007575 False 3559 mRNA 0.40 11 11781973 11791718
TCONS_00007576 True 2215 mRNA 0.47 12 11783464 11792766

Neighbor

gene id symbol gene type direction distance location
XLOC_003962 CR848705.2 coding downstream 75837 11639483 ~ 11706136 (-)
XLOC_003961 si:dkey-28e7.3 coding downstream 156343 11595973 ~ 11625630 (-)
XLOC_003960 NA coding downstream 180093 11594994 ~ 11601880 (-)
XLOC_003959 krt99 coding downstream 206903 11565996 ~ 11575070 (-)
XLOC_003958 krt15 coding downstream 263504 11515778 ~ 11518469 (-)
XLOC_003964 wipf2a coding upstream 51357 11844123 ~ 11890001 (-)
XLOC_003965 si:ch211-69b7.6 coding upstream 98814 11891580 ~ 11910225 (-)
XLOC_003966 abcc10 coding upstream 118633 11911399 ~ 11965033 (-)
XLOC_003967 sp2 coding upstream 190699 11983465 ~ 12008001 (-)
XLOC_003968 socs7 coding upstream 216969 12009735 ~ 12051805 (-)
XLOC_003954 BX324177.9 misc downstream 334488 11447189 ~ 11447485 (-)
XLOC_003953 BX324177.8 misc downstream 335988 11445689 ~ 11445985 (-)
XLOC_003952 BX324177.23 misc downstream 343786 11437891 ~ 11438187 (-)
XLOC_003951 BX324177.16 misc downstream 346230 11435447 ~ 11435743 (-)
XLOC_003950 BX324177.18 misc downstream 354799 11426878 ~ 11427174 (-)
XLOC_003971 BX469912.7 misc upstream 368892 12161658 ~ 12161955 (-)
XLOC_003973 BX469912.11 misc upstream 375236 12168002 ~ 12168298 (-)
XLOC_003974 BX469912.4 misc upstream 376595 12169361 ~ 12169654 (-)
XLOC_003979 BX469912.8 misc upstream 428124 12220890 ~ 12221186 (-)
XLOC_003983 FO904934.1 misc upstream 461094 12253860 ~ 12254156 (-)
XLOC_003955 NA non-coding downstream 330038 11451660 ~ 11451935 (-)
XLOC_003946 NA non-coding downstream 377083 11404596 ~ 11404890 (-)
XLOC_003941 NA non-coding downstream 424786 11356893 ~ 11357187 (-)
XLOC_003972 NA non-coding upstream 372957 12165723 ~ 12166007 (-)
XLOC_003975 NA non-coding upstream 393088 12185854 ~ 12186144 (-)
XLOC_003977 NA non-coding upstream 420383 12213149 ~ 12213431 (-)
XLOC_003997 NA non-coding upstream 636617 12429383 ~ 12491279 (-)
XLOC_003998 NA non-coding upstream 637389 12430155 ~ 12465409 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000305_00180748_00185076 CDC6 coding CI01000305 null 179883 ~ 185076 (+)
bowfin (Amia calva) G46034 NA non-coding CM030125.1 CM030125.1 38588879 ~ 38590159 (+)
mexican tetra (Astyanax mexicanus) G42599 cdc6,LOC107753851,LOC107718871,LOC102777898 non-coding NC_035901.1 CM008304.1 14870356 ~ 14877360 (+)