XLOC_004049 (ghrh)



Basic Information


Item Value
gene id XLOC_004049
gene name ghrh
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007122.7
NCBI id CM002895.2
chromosome length 45484837
location 15345654 ~ 15435495 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00007727
AACTCACTACAATCACCAACAGTAGAGGCTGGGAATAAAATCAAATCCTCAGTGAGAGAAACATCTTGTTTCCGTCACATTTGTTACAAACCTGGACCAGAAATCTTTGATCATGCAAGTGGGAGTAATTCAGAGAACTGCCTTGCTAGTGCTCTGCTGCTTGTTACTATCAGCATCATCTTCCCCAGTCTACCCAGCACTGAAGTTTGGAAGACATGCTGATGCCATCTTTACCAACAGCTACAGAAAAGTTCTTGGTCAAATATCTGCCAGAAAATTTCTTCAAACTGTTATGGGAAAAAGACTTGGACCAGAAACTGAAAGCAATGTAAAGCGTCAGTCAAGTATGTATGGAAACACCTACAAGCAAGATGTGGACATGAATGTCATTGAGAGTGAACAAAGTTACAGAGACCCACAAAAATTTAAGTTTGCATTAATTATGCACTGAATTAAAATGTAAAGTGCATATacattatgaatatttaaaaggGAACTATTGCATTTGCTGTATTTCATATTGGATAATTAAAACTCACACATGTTATAATCAGCCAATGTTCAGATGATCTGCCACAGTGAATACTGAATTTCAAATATTTAATAGGCTGTATTTTGCATCCGTACTTTAGAAAGAATATACAAGTGTTTAGTAGCCTTTATGACCATTTGCTAAGCTCCTGCTTTGAAATGATGCCAATTCTATTTGTATAAGTTGTACCTTATAAGCATGTACAGTATACAGAAATGTGTACACCTCTGGCTGAGGACAGGTAGAAGGTAGCTTCTTaactcattatttaaaataatattttctattatttggcaactttttattattttttgtttgttagtacAGTCTTACAAATTATTAATCCAACAGAAATCAATATGAAAGAACCCCTATTATGgggttttgaaaatgaccttccatgcactGTGTAAAGCAGCtctaagtgaataaaaacatccagcttaaagaggtttaaatctgaaa

Function


symbol description
ghrh Enables growth hormone-releasing hormone activity. Acts upstream of or within signal transduction. Predicted to be located in extracellular region. Predicted to be active in extracellular space; perikaryon; and terminal bouton. Human ortholog(s) of this gene implicated in autoimmune polyendocrine syndrome type 1; endometrial cancer; ovarian cancer; and renal cell carcinoma. Orthologous to human GHRH (growth hormone releasing hormone).

GO:

id name namespace
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway biological_process
GO:0060124 positive regulation of growth hormone secretion biological_process
GO:0030252 growth hormone secretion biological_process
GO:0008284 positive regulation of cell population proliferation biological_process
GO:0040018 positive regulation of multicellular organism growth biological_process
GO:0007165 signal transduction biological_process
GO:0043005 neuron projection cellular_component
GO:0005576 extracellular region cellular_component
GO:0005615 extracellular space cellular_component
GO:0043195 terminal bouton cellular_component
GO:0043204 perikaryon cellular_component
GO:0031770 growth hormone-releasing hormone receptor binding molecular_function
GO:0051428 peptide hormone receptor binding molecular_function
GO:0005179 hormone activity molecular_function
GO:0005184 neuropeptide hormone activity molecular_function
GO:0016608 growth hormone-releasing hormone activity molecular_function

KEGG:

id description
ko04080 Neuroactive ligand-receptor interaction
ko04935 Growth hormone synthesis, secretion and action

ZFIN:

id description
ZDB-GENE-070426-1 Enables growth hormone-releasing hormone activity. Acts upstream of or within signal transduction. Predicted to be located in extracellular region. Predicted to be active in extracellular space; perikaryon; and terminal bouton. Human ortholog(s) of this gene implicated in autoimmune polyendocrine syndrome type 1; endometrial cancer; ovarian cancer; and renal cell carcinoma. Orthologous to human GHRH (growth hormone releasing hormone).

Ensembl:

ensembl_id ENSDARG00000069481

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00007727 True 997 mRNA 0.35 4 15345654 15435495

Neighbor


gene id symbol gene type direction distance location
XLOC_004048 NA coding downstream 32055 15311381 ~ 15313599 (-)
XLOC_004047 rpn2 coding downstream 48444 15225534 ~ 15297210 (-)
XLOC_004046 slc1a8a coding downstream 255090 15068307 ~ 15090564 (-)
XLOC_004045 CR550302.1 coding downstream 326127 15018138 ~ 15019527 (-)
XLOC_004044 elavl1b coding downstream 343942 14955484 ~ 15001712 (-)
XLOC_004050 NA coding upstream 321231 15756726 ~ 15761871 (-)
XLOC_004051 FP016142.5 coding upstream 339957 15775452 ~ 15780923 (-)
XLOC_004052 FP016142.4 coding upstream 360598 15796093 ~ 15797568 (-)
XLOC_004053 FP016142.3 coding upstream 362763 15798258 ~ 15799923 (-)
XLOC_004054 FP016142.7 coding upstream 366955 15802450 ~ 15803637 (-)
XLOC_004019 CR450764.8 misc downstream 2653963 12691395 ~ 12691691 (-)
XLOC_004015 CR450764.4 misc downstream 2723887 12621518 ~ 12621767 (-)
XLOC_004013 CABZ01022569.1 misc downstream 2754358 12590999 ~ 12591296 (-)
XLOC_004008 BX000700.19 misc downstream 2832392 12512966 ~ 12513262 (-)
XLOC_004006 BX000700.27 misc downstream 2845392 12499966 ~ 12500262 (-)
XLOC_004063 CR854846.1 misc upstream 691887 16127382 ~ 16127678 (-)
XLOC_004042 NA non-coding downstream 471524 14873329 ~ 14874130 (-)
XLOC_004041 CU019562.1 non-coding downstream 516330 14827374 ~ 14829324 (-)
XLOC_004039 NA non-coding downstream 586566 14754905 ~ 14759088 (-)

Expression



Co-expression Network