XLOC_004155 (skib)



Basic Information


Item Value
gene id XLOC_004155
gene name skib
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007122.7
NCBI id CM002895.2
chromosome length 45484837
location 25782721 ~ 25829712 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00007937
gagagagaaagagagagagggagagcgaGACTTGCACACACTCTCATAGTAAAGCGGAGGCAACTGCGCTTTTACACCAGCCACGCATTTTGCGCGTGAGTACTGTGATTTACACGGATTGAAGAATTACATTTCGACCAAAACTTTACACTTTTTGTGGGGGAGGATTTTCGCCTCGCTCGGAACTCCGGTTCTTTCTGGTACGACTTACAGAATCGGACATGAAGCAGTTGAATGGATTACGAGGCGGTGTTTTACGCTTTCGGAACTGACACGGACTGTCGCGACTCACATTTATGAATCTGTTGTGATTAAACTGCCCAGGTTTAAACATGGAGGCTCCTTCCAGCTTTCAGCCGCATCCAGGACTTCAGCAAACTCTCAAGCAGTTTCACTTGAGCTCCATGAGCTCCCTCGGCGGACCGGCAGCCTTCTCGGCCCGGTGGCAGCAGGACATGCTGTTCAAAAAGGACGGTAAGAGCGCCGAGGTGCTCGTGAACCTCCCCGCGCAGACGCCCCCGGTCATGCCGGGACCCCTGTTCATCCCGTCCGACCGCTCCACCGAGAGGTGCGAGACGGTCCTGGAGCGGGAGACTATTTCGTGCTTCGTGGTGGGCGGCGAGAAGCGCCTGTGCCTGCCGCAGATCCTCAATAGCGTCCTGCGAGACTTTTCCCTCCAGCAGATCAACTCTGTGTGCGACGACCTGCACATCTACTGCTCCAGGTGCACGGCGGACCAGCTGGAGATCCTCAAAGTTATGGGCATCCTGCCCTTCTCGGCCCCCTCGTGCGGACTCATCACACAAACAGACGCCGAGCGCCTCTGCAATGCCCTCATCTACGGCGGCACGTTCCCCCCGCACGCCGACAAAGAGTTGTCCTGCTCCATTGAGCTGGAGCGCACAGAGAAGAGCTTCAAAGTTTACCACGAATGCTTTGGGAAGTGCAAGGGCCTGTTCGTACCCGAACTCTACACCAGCCCCAACGCGGCGTGCATACAGTGCTTGGACTGCAGGCTCATGTTCCCGACCCACAAGTTCGTGGTGCACAGTCATAAAAGGCTGGAGAACAGAACCTGTCACTGGGGCTTCGACTCGTCCAACTGGAGGGCTTATATTCTTCTAGATCAAGACTATAGCGAGAAAGAGGAGAACAGCACACTGCAGCAGCTCCTCACTGAGTTAAAGGGAAAATTTGAAATGGGGAACAAGCACAAGACATCTTACAAGgCATACAGTCCTATTCCCTCCAAAAAGCTTAAACATGATCGCTCCAGATCGCCATCAGCAGATAGAGAGAAGCCAGCTGATTGGCTACAGTCTCTGGCGGCTTCTGCTAACAAGGATCTTAAGCAGCTCCAGTTCAAGCAGAGACCTTCAGCCTTCAGGCCCTGGTCTCCCAGAGTTCCCTCTGCTGAGCGAGAGACTCCCAATCACAAGTATGAGAGATCGCTCGCTAAAACGCAAGACAATCTGGCAGTTCCAAATGTGTCTCTGCCCATTGCTGCCTTCAAAAATAATGAGCAGCCAGCACACCGTTTCTCTCAGCCCACTGAGAGCCACAACACAGGCAAGACGGAGAGCTCCAGGCCAAGAAAGAGATGGCCGTCAGCAGAGAGACAATCACAGCCAGCCACCAAAACCTCTCTGTGCACTCCAATCAAACAGCGGCTGCAGGAGAACCACGACTCAGATGAGGAAATCCAGGTGGACAACTGTGCTGAAGTTGCTGTCTCTCGTTCGCTGATGTCTCCTCCCTTCACCAATGGTGTCGGGGTGATGACCCTCAGCCCTCACAGCTCTGcagaggtgcatgatgggagggCGAGACTGGCAGCGGGTCATTGTTCAGAGCTGGAGCTCCTCAAGCAGACGCTCAGCAGTGACCTGAGCTCCAAAGAGGCCAGAGAGAAGTTCCTGCAGGAGATCATCCGCATGAGGGTGAAGCAGGAGGAGAAACTGGCAGCCGCTCTGCAAGCCAAACGCAGCCTGCAGCAGGAGCTGGAGTTTGTCAGGGTGACTAAGAAGGGCCGGCTGAGGGAGGCCATCGAAGCCAAGCGGAACCTAAGGAAGGAGATCGAGCGCCTCCGTGTGGAGTGTGAGAAGAAGGTGCGGGACGCCAGCGAGTCCTGCGACAGGCTGAAGAGGGATTTGGACAGAGAGAGACGGACCCGTGTCTGTGACAAGAACTGTGAAGCAGGACGTCTGAGGGCCAAATACTCCTCACAGATTGAGGATCTGCAGATGAAGCTCCAGCAGGCAGAAGTGGACCGTGAACAGCTGAGAGAAGACCTGCTGAAGGAACGAGACGCCCGACAAAACCTGGAGCGGGTCGTAAAAGAGCTTCAGGAGCAACTGGGCCACAAAGCAGAAACGGAGGCTAACACACAGCCCACCAAAGGAGATCAAGACATTTCTTAAACATTCACACTAATGAGTTTAGACTTTGATTTGAGGATGAGTAGAGGACGCCTCTAAAGcctcatggaaaaaaaaactaccGTACTGCAGCACAGAAGAATGGTAAAGAAACGAATTCACAGCGTACGTTTACCAAATGAACTGAATCATGAACTCAAGAAACTGGAAAAGGAAACGTAAACGTGTGAAACAGACTCGCCTTCAGTTAGCTTCTCAAAGCTAATCGAAGGAAACTATTTtgttataagctatttaaaaaaattttcgcAAAGATACTTGAAGAATATTTGGGAAGCGAGCGTGTTTTCTATTCACTTTGCGCTGACAGTAGCAGGCCAACGATCTGCTAGTGCCACCGAGACTCTGTAAACTAGAAAGTGTTACAAGCCAGAATTCTACATAGCACACCGGTGTTGTCATTATCATTGTTTGCTCGCtttcatttgaccttttttggtttgttttggctGTTGTATTGAAATAGTTTGCATGTGCGACCATGCTATGGTGCAGAAAAGCTTTATTATAAACCTACGTTCATTTTTATTATGGTATGTTTAATTATCATGTACTTAAAACCCTATAGTATTGACGTCGATCAATATGAGATGAATCCTTACCCTCTCTCCTGAACTTCAGTATCAAGTATTAATTGCTTTAATTATCGCTATTTTAAACAGTCTAAGCGACTGGCATCACTCCACGCTCCATTTCGACGgtaaaatgaatgttttgttgGTTCAGAATCGGAATTAAGTGACAGAAATCAATTATCAGTCACTCCTTTTAGGGCTTGTTTAAGGTATAAAAAAAGAAGCTGTTAAAGAAAATAACATTTCTACTTATATAGAAAATaaggatatatatttttttactttctaccaaaaaaaaaa
>TCONS_00007938
GCACATCTACTGCTCCAGGTGCACGGCGGACCAGCTGGAGATCCTCAAAGTTATGGGCATCCTGCCCTTCTCGGCCCCCTCGTGCGGACTCATCACACAAACAGACGCCGAGCGCCTCTGCAATGCCCTCATCTACGGCGGCACGTTCCCCCCGCACGCCGACAAAGAGTTGTCCTGCTCCATTGAGCTGGAGCGCACAGAGAAGAGCTTCAAAGTTTACCACGAATGCTTTGGGAAGTGCAAGGGCCTGTTCGTACCCGAACTCTACACCAGCCCCAACGCGGCGTGCATACAGTGCTTGGACTGCAGGCTCATGTTCCCGACCCACAAGTTCGTGGTGCACAGTCATAAAAGGCTGGAGAACAGAACCTGTCACTGGGGCTTCGACTCGTCCAACTGGAGGGCTTATATTCTTCTAGATCAAGACTATAGCGAGAAAGAGGAGAACAGCACACTGCAGCAGCTCCTCACTGAGTTAAAGGGAAAATTTGAAATGGGGAACAAGCACAAGACATCTTACAAGTTAGCAGGACCGTCAGTGGAAAGACCGTCGGCTCAGCATATTCTGCTTATTAAAAATCTAGAATTTTTATACTTGGTGTCAATGTGAAATATATTGCACCAATATTTTAagtatgtatttgtatgtatttaagTGCATCTGTTGTTAATTTTGTCTGTCTGTAGTTTGTTTTcaagtaaataatactttaatttgagtgaaaatacattattagaaagaaaaataaacagcaaTGATGTGTTATGTTA

Function


symbol description
skib Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and SMAD binding activity. Acts upstream of or within cartilage development; dorsal/ventral pattern formation; and heart looping. Located in nucleus. Is expressed in central nervous system. Used to study craniosynostosis. Orthologous to human SKI (SKI proto-oncogene).

GO:

id name namespace
GO:0051216 cartilage development biological_process
GO:0000122 negative regulation of transcription by RNA polymerase II biological_process
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway biological_process
GO:0030514 negative regulation of BMP signaling pathway biological_process
GO:0009953 dorsal/ventral pattern formation biological_process
GO:0001947 heart looping biological_process
GO:0005634 nucleus cellular_component
GO:0005667 transcription regulator complex cellular_component
GO:0046332 SMAD binding molecular_function
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding molecular_function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-990715-10 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and SMAD binding activity. Acts upstream of or within cartilage development; dorsal/ventral pattern formation; and heart looping. Located in nucleus. Is expressed in central nervous system. Used to study craniosynostosis. Orthologous to human SKI (SKI proto-oncogene).

Ensembl:

ensembl_id ENSDARG00000008034

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00007937 False 3313 mRNA 0.50 7 25782721 25829712
TCONS_00007938 True 771 mRNA 0.46 2 25814441 25829006

Neighbor


gene id symbol gene type direction distance location
XLOC_004154 plch2b coding downstream 5403 25752198 ~ 25777318 (-)
XLOC_004153 brpf3a coding downstream 48304 25712772 ~ 25734417 (-)
XLOC_004152 CR933820.1 coding downstream 112766 25669839 ~ 25669955 (-)
XLOC_004151 si:dkey-245f22.3 coding downstream 243398 25528557 ~ 25539323 (-)
XLOC_004150 NA coding downstream 305741 25475305 ~ 25476980 (-)
XLOC_004156 tmem51b coding upstream 3507 25833219 ~ 25853212 (-)
XLOC_004157 kaznb coding upstream 28229 25857941 ~ 26180714 (-)
XLOC_004158 prdm2b coding upstream 359991 26189703 ~ 26217510 (-)
XLOC_004159 foxj3 coding upstream 399206 26228918 ~ 26362334 (-)
XLOC_004160 utp3 coding upstream 540669 26370381 ~ 26375575 (-)
XLOC_004063 CR854846.1 misc downstream 9655043 16127382 ~ 16127678 (-)
XLOC_004019 CR450764.8 misc downstream 13091030 12691395 ~ 12691691 (-)
XLOC_004015 CR450764.4 misc downstream 13160954 12621518 ~ 12621767 (-)
XLOC_004013 CABZ01022569.1 misc downstream 13191425 12590999 ~ 12591296 (-)
XLOC_004008 BX000700.19 misc downstream 13269459 12512966 ~ 12513262 (-)
XLOC_004147 NA non-coding downstream 373825 25368112 ~ 25408896 (-)
XLOC_004144 dre-mir-499 non-coding downstream 577478 25205153 ~ 25205243 (-)
XLOC_004142 CR628365.2 non-coding downstream 814834 24967771 ~ 24967887 (-)
XLOC_004165 CR847934.1 non-coding upstream 918580 26748292 ~ 26748429 (-)
XLOC_004167 NA non-coding upstream 1672493 27502205 ~ 27507973 (-)
XLOC_004169 NA non-coding upstream 1713866 27543578 ~ 27625465 (-)
XLOC_004173 BX601648.1 non-coding upstream 1954046 27783758 ~ 27806767 (-)
XLOC_004174 NA non-coding upstream 1971147 27800859 ~ 27809715 (-)

Expression



Co-expression Network