XLOC_004199 (ace2)


Basic Information

Item Value
gene id XLOC_004199
gene name ace2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007122.7
NCBI id CM002895.2
chromosome length 45484837
location 29981678 ~ 29996357 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00008041
AGAATCGGTGGGACAAGGCTGTGGTCATGTGTGCTCGCTGGCTCCTGCTTTTGGCCTTGGCCTCTGTGGCCTGCTGTCAGACTGTGGAGGACAGAGCAAGGGAATTCCTCAACAAATTTGATGAAGaggcatctgacatcatgtaccaGTACACCCTTGCATCCTGGGCCTACAACACAGATATCTCCCAGGAAAATGCAGATAAAGAGGCAGAGGCATATGCAATCTGGAGCGAGTACTACAACAAGATGTCAGAAGAGTCTAATGCCTACCCCATAGACCAAATATCGGATCCAATCATTAAAATGCAGCTCCAGAAGCTTCAAGATAAAGGATCTGGGGCCCTTTCACCTGACAAAGCTAGTGAACTGAGAAATATCATGTCAGAGATGAGCACTATTTACAACACGGCGACTGTGTGCAAAATAGACGACCCCACCGATTGTCAGACTTTGGAGCCAGGCCTAGAGAGTATCATGGCAGAGAGCAGAGACTATGATGAGCGTCTGCATGTATGGGAAGGCTGGAGAGTGGCCACAGGGATGAAGATGAGACCCTTGTATGAAAAATACGTCGACCTGAAGAATGAAGCTGCCAAGCTCAACAACTACGAAGACCATGGAGATTATTGGAGGGGAGATTATGAAACTATTGATGATCCCAAATACAGTTACTCCCGAGACCAAGTTATAGAAGACGCCAGGCGCATTTACAAAGAGATCTTACCACTGTACAAAGAGCTTCATGCTTACGTGAGAGCAAAACTGCAAGACGTCTATCCTGGTCACATTGGCTCTGATGCCTGTCTTCCAGCACATTTGCTTGGTGATATGTGGGGACGGTTTTGGACCAACTTGTATCCTCTCATGATCCCATATCCAGACAGGCCTGATATTGATGTGAGCTCCGCAATGGTGGAGCAGGGTTGGGATGAAATCCGTCTGTTTAAAGAGGCAGAAAAATTCTTCATGTCTGTAAACATGCCTGCAATGTTTGACAACTTCTGGAACAACTCAATGTTTATTAAACCTGAAGAAAGAGATGTGGTTTGCCATCCTACCGCATGGGATATGGGAAACAGAAAGGACTTCAGAATCAAAATGTGCACTAAAGTGAACATGGATGATTTCTTAACTGTCCACCATGAGATGGGGCACAACCAGTACCAAATGGCTTACCGAAACCACCCATACCTGCTGAGAGATGGTGCCAATGAGGGCTTCCATGAGGCTGTTGGAGAGATCATGTCGCTTTCTGCTGCCACTCCGTCTCACCTGCAGTCACTGGGGCTTCTGCCTTCCGACTTCAAACAGGATTATGAGACAGATATTAACTTCCTGTTGAAGCAGGCTCTCACCATAGTGGGCACTCTGCCCTTCACCTACATGCTGGAGGAATGGAGGTGGCAAGTCTTCAAAGCAAAAATCCCCAAAGATGAGTGGATGCAGCAGTGGTGGCAGATGAAGAGAGAACTTGTTGGAGTGGCCGAGGCTGTTCCCAGAGATGAGACGTACTGTGACCCTCCAGCACTTTTCCACGTTTCTGGAGATTACTCTTTCATTAGGTACTTCACTAGAACCATATATCAGTTCCAGTTTCAAGAGGCATTATGTAAGGCAGCTGGCCACACCGGTCCCCTTTACAAATGTGACATTACAAACTCAACCAAAGCTGGTGACAAACTCAGGCATATGCTTGAGTTAGGCCGATCCATGTCTTGGACTCGTGCTTTGGAAGAAGTTGCAGGAACCACAAAGATGGACTCACAGCCACTGCTACATTACTTCAGTACTCTCATGGAGTGGTTGAAGGAGGAAAACCAGAAGAACAACAGAGTTCCTGGCTGGAACGTCAATGTTAACCCTGGTGTACTTACATCATCTTTTATAAATGATGCAGAAATTTCAGAAAATGCCTTCAAAGTCAGAATAAGCCTTAAATCTGCCCTGGGAAATGAAGCATACACCTGGAACGCAAATGACATTTATCTCTTTAAGTCCACTATGGCCTTTGCCATGCGCCAGTACTACTTGAAAGAAAAGAACACAGATGTAAATTTCACGCCAGAGAATATCCACACGTACAATGAAACCGCCAGAATATCCTTTAAATTTGCTGTGATGGATCCAACCAAAACAGGCACAGTTATTCCAAAGGCAGAAGTAGAGAATGCTATCTGGCAGGAGAGAGATCGCATCAATGGTGCATTTCTACTAAGTGACGAAACTCTGGAATTTGTTGGTCTGATGGCAACATTAGCACCACCAAAAGAGGAAAAAATCACAATTTGGCTGGTGGTGTTTGGGGTAGTAATGGGAGTGACTGTCCTTGCGGGGATCTACCTCGTTACCACAGGGATATTAAATAGGAAGAAgaaAGCTAAGAAGGCTAAGGAGGCCTCAGTTGAGAACCCATACGATGGATCAGATGATGGTGAAGTGAACAAAGCCTTTGAGGAAGACATTGAACAAACAGGACTGTAAACAAAtatgctttcagaaaaaaaaaatcagaaaggtTCCACATCATtgcatgattttgttttttaaaacaatgaacagacgTCTTTTTCGTGTgtctttacaaatatttatttgaatgcaTGATATAGGAAAGATATATAGTATGAACACATAATAATAAGATACAATTACTGTAACTATGAAAATAGAAATTGCAAGCTTATACATACGGTACCAATGTAAATAGGGGTTAATATTGTAAAGCAGTTATATGTTTTTCTAAGAGGTTTGATTAAATACTACAACAATATAACCAGTGTTTCCTACATTATAATTAAAAGTAGCTCAATGTAATAGTGTGAAAGGAAACAGTGACACCTTCTAAATAAAATCCTAAATATGACTTAA
>TCONS_00008042
CAAGGCTGTGGTCATGTGTGCTCGCTGGCTCCTGCTTTTGGCCTTGGCCTCTGTGGCCTGCTGTCAGACTGTGGAGGACAGAGCAAGGGAATTCCTCAACAAATTTGATGAAGaggcatctgacatcatgtaccaGTACACCCTTGCATCCTGGGCCTACAACACAGATATCTCCCAGGAAAATGCAGATAAAGAGGCAGAGGCATATGCAATCTGGAGCGAGTACTACAACAAGATGTCAGAAGAGTCTAATGCCTACCCCATAGACCAAATATCGGATCCAATCATTAAAATGCAGCTCCAGAAGCTTCAAGATAAAGGATCTGGGGCCCTTTCACCTGACAAAGCTAGTGAACTGAGAAATATCATGTCAGAGATGAGCACTATTTACAACACGGCGACTGTGTGCAAAATAGACGACCCCACCGATTGTCAGACTTTGGAGCCAGGCCTAGAGAGTATCATGGCAGAGAGCAGAGACTATGATGAGCGTCTGCATGTATGGGAAGGCTGGAGAGTGGCCACAGGGATGAAGATGAGACCCTTGTATGAAAAATACGTCGACCTGAAGAATGAAGCTGCCAAGCTCAACAACTACGAAGACCATGGAGATTATTGGAGGGGAGATTATGAAACTATTGATGATCCCAAATACAGTTACTCCCGAGACCAAGTTATAGAAGACGCCAGGCGCATTTACAAAGAGATCTTACCACTGTACAAAGAGCTTCATGCTTACGTGAGAGCAAAACTGCAAGACGTCTATCCTGGTCACATTGGCTCTGATGCCTGTCTTCCAGCACATTTGCTTGGTGATATGTGGGGACGGTTTTGGACCAACTTGTATCCTCTCATGATCCCATATCCAGACAGGCCTGATATTGATGTGAGCTCCGCAATGGTGGAGCAGGGTTGGGATGAAATCCGTCTGTTTAAAGAGGCAGAAAAATTCTTCATGTCTGTAAACATGCCTGCAATGTTTGACAACTTCTGGAACAACTCAATGTTTATTAAACCTGAAGAAAGAGATGTGGTTTGCCATCCTACCGCATGGGATATGGGAAACAGAAAGGACTTCAGAATCAAAATGTGCACTAAAGTGAACATGGATGATTTCTTAACTGTCCACCATGAGATGGGGCACAACCAGTACCAAATGGCTTACCGAAACCACCCATACCTGCTGAGAGATGGTGCCAATGAGGGCTTCCATGAGGCTGTTGGAGAGATCATGTCGCTTTCTGCTGCCACTCCGTCTCACCTGCAGTCACTGGGGCTTCTGCCTTCCGACTTCAAACAGGATTATGAGACAGATATTAACTTCCTGTTGAAGCAGGCTCTCACCATAGTGGGCACTCTGCCCTTCACCTACATGCTGGAGGAATGGAGGTGGCAAGTCTTCAAAGCAAAAATCCCCAAAGATGAGTGGATGCAGCAGTGGTGGCAGATGAAGAGAGAACTTGTTGGAGTGGCCGAGGCTGTTCCCAGAGATGAGACGTACTGTGACCCTCCAGCACTTTTCCACGTTTCTGGAGATTACTCTTTCATTAGGTACTTCACTAGAACCATATATCAGTTCCAGTTTCAAGAGGCATTATGTAAGGCAGCTGGCCACACCGGTCCCCTTTACAAATGTGACATTACAAACTCAACCAAAGCTGGTGACAAACTCAGGCATATGCTTGAGTTAGGCCGATCCATGTCTTGGACTCGTGCTTTGGAAGAAGTTGCAGGAACCACAAAGATGGACTCACAGCCACTGCTACATTACTTCAGTACTCTCATGGAGTGGTTGAAGGAGGAAAACCAGAAGAACAACAGAGTTCCTGGCTGGAACGTCAATGTTAACCCTGGTGTACTTACATCATCTTTTATAAATGATGCAGAAATTTCAGAAAATGCCTTCAAAGTCAGAATAAGCCTTAAATCTGCCCTGGGAAATGAAGCATACACCTGGAACGCAAATGACATTTATCTCTTTAAGTCCACTATGGCCTTTGCCATGCGCCAGTACTACTTGAAAGAAAAGAACACAGATGTAAATTTCACGCCAGAGAATATCCACACGTACAATGAAACCGCCAGAATATCCTTTAAATTTGCTGTGATGGATCCAACCAAAACAGGCACAGTTATTCCAAAGGCAGAAGTAGAGAATGCTATCTGGCAGGAGAGAGATCGCATCAATGGTGCATTTCTACTAAGTGACGAAACTCTGGAATTTGTTGGTCTGATGGCAACATTAGCACCACCAAAAGAGGAAAAAATCACAATTTGGCTGGTGGTGTTTGGGGTAGTAATGGGAGTGACTGTCCTTGCGGGGATCTACCTCGTTACCACAGGGATATTAAATAGGAAGAAggaaAGCTAAGAAGGCTAAGGAGGCCTCAGTTGAGAACCCATACGATGGATCAGATGATGGTGAAGTGAACAAAGCCTTTGAGGAAGACATTGAACAAACAGGACTGTAAACAAAtatgctttcagaaaaaaaaaatcagaaaggtTCCACATCATtgcatgattttgttttttaaaacaatgaacagacgTCTTTTTCGTGTgtctttacaaatatttatttgaatgcaTGATATAGGAAAGATATATAGTATGAACACATAATAATAAGATACAATTACTGTAACTATGAAAATAGAAATTGCAAGCTTATACATACGGTACCAATGTAAATAGGGGTTAATATTGTAAAGCAGTTATATGTTTTTCTAAGAGGTTTGATTAAATACTACAACAATATAACCAGTGTTTCCTACATTATAATTAAAAGTAGCTCAATGTAATAGTGTGAAAGGAAACAGTGACACCTTCTAAATAAAATCCTAAATATGACTT

Function

symbol description
ace2 Predicted to enable carboxypeptidase activity and metallopeptidase activity. Predicted to act upstream of or within proteolysis. Predicted to be located in cytoplasm; extracellular region; and membrane. Predicted to be integral component of membrane. Predicted to be active in extracellular space and plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including COVID-19; avian influenza; cerebral malaria; hypertension (multiple); and respiratory syncytial virus infectious disease. Orthologous to human ACE2 (angiotensin converting enzyme 2).

GO:

id name namespace
GO:0006508 proteolysis biological_process
GO:0005886 plasma membrane cellular_component
GO:0005615 extracellular space cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0004180 carboxypeptidase activity molecular_function
GO:0046872 metal ion binding molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0008233 peptidase activity molecular_function
GO:0008237 metallopeptidase activity molecular_function
GO:0008241 peptidyl-dipeptidase activity molecular_function

KEGG:

id description
ko04614 Renin-angiotensin system
ko04974 Protein digestion and absorption
ko05171 Coronavirus disease - COVID-19
ko01002 Peptidases and inhibitors
ko03000 Transcription factors
ko04147 Exosome

ZFIN:

id description
ZDB-GENE-041114-6 Predicted to enable carboxypeptidase activity and metallopeptidase activity. Predicted to act upstream of or within proteolysis. Predicted to be located in cytoplasm; extracellular region; and membrane. Predicted to be integral component of membrane. Predicted to be active in extracellular space and plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including COVID-19; avian influenza; cerebral malaria; hypertension (multiple); and respiratory syncytial virus infectious disease. Orthologous to human ACE2 (angiotensin converting enzyme 2).

Ensembl:

ensembl_id ENSDARG00000016918

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00008041 False 2870 mRNA 0.43 18 29981678 29996357
TCONS_00008042 True 2856 mRNA 0.43 18 29981680 29996344

Neighbor

gene id symbol gene type direction distance location
XLOC_004198 CU652893.1 coding downstream 19777 29961114 ~ 29961901 (-)
XLOC_004197 pir coding downstream 34751 29917613 ~ 29946927 (-)
XLOC_004196 vegfd coding downstream 65071 29889828 ~ 29916607 (-)
XLOC_004195 cybb coding downstream 147980 29795155 ~ 29833698 (-)
XLOC_004194 plekha3 coding downstream 213624 29756860 ~ 29768054 (-)
XLOC_004200 CR318645.1 coding upstream 104785 30101142 ~ 30101257 (-)
XLOC_004201 scml2 coding upstream 109825 30106182 ~ 30158609 (-)
XLOC_004202 cflara coding upstream 336602 30332959 ~ 30341431 (-)
XLOC_004203 tmem169a coding upstream 351916 30348273 ~ 30352333 (-)
XLOC_004204 pecr coding upstream 359085 30355442 ~ 30364847 (-)
XLOC_004063 CR854846.1 misc downstream 13854000 16127382 ~ 16127678 (-)
XLOC_004019 CR450764.8 misc downstream 17289987 12691395 ~ 12691691 (-)
XLOC_004015 CR450764.4 misc downstream 17359911 12621518 ~ 12621767 (-)
XLOC_004013 CABZ01022569.1 misc downstream 17390382 12590999 ~ 12591296 (-)
XLOC_004008 BX000700.19 misc downstream 17468416 12512966 ~ 12513262 (-)
XLOC_004193 NA non-coding downstream 244431 29734578 ~ 29737247 (-)
XLOC_004190 NA non-coding downstream 436689 29537982 ~ 29544989 (-)
XLOC_004188 NA non-coding downstream 661759 29099927 ~ 29319919 (-)
XLOC_004187 NA non-coding downstream 893052 29085366 ~ 29088626 (-)
XLOC_004211 NA non-coding upstream 1203862 31200219 ~ 31202839 (-)
XLOC_004212 NA non-coding upstream 1208568 31204925 ~ 31211308 (-)
XLOC_004216 NA non-coding upstream 2153861 32150218 ~ 32157526 (-)
XLOC_004217 NA non-coding upstream 2369555 32365912 ~ 32391388 (-)

Expression


Co-expression Network