XLOC_004214 (man2b1)


Basic Information

Item Value
gene id XLOC_004214
gene name man2b1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007122.7
NCBI id CM002895.2
chromosome length 45484837
location 31258116 ~ 31276080 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00008070
ATTCAGGCTGTCATGTGAGGGCAGTTTCATTTTCATCATGGCTTCGGAACCATGGCTTCACATCAGTCTTCtgctcttgttttgtttttcgcTTGTGTTTTCTTTGCCCACGGGTCGAAACTCCATCTGCGGTTATAAGTCATGTCCAGCCACAAAGCCATCCATGCTGAACGTCCATCTGGTTCCACACACACATGATGATGTCGGCTGGCTCAAGACTGTGGATCAGTACTTTTACGGAGaccGAAATAACATCCAGCATGCAGGTGTTCAGTATATTCTGGACTCAGTGATCGATCAGCTACAGAAGGATCCAGCTCGACGCTTTATCTATGTTGAGACGGCCTTCTTTTACCGCTGGTGGAGACAGCAGAACCAGAACACACGCCGCATTGTGACCCAGCTGGTCAATGAGGGTCGTCTTGAGTTCATAAATGGTGGCTGGTGCATGAGCGATGAGGCGACCACACACTACAGCGCTGTCATTGATCAGATGACTCTGGGGCTGCGATTCCTCAATGACACTTTCGGCGAGTGTGGACGTCCCCGGGTGGCTTGGCACATTGACCCCTTCGGACACGCCAGAGAACACGCCTCCATCTTTGCTCAGATGGGCTATGACGGCTTCTTCTTTGGCCGCTTGGACTACCAGGACAAGGACCGCAGGATGAAGACCAAAGAGATGGAAATGCTCTGGAGGGCCAGTGAGAGCCTGACTCCACCTATTGCCGATCTCTTCACAGGGGTTCTCCCCAATGGCTATAACCCTCCTGAGGGCTTCTGCTGGGATCAGTCATGTGATGATGCCCCCATTAGAGACGACCCAGATCTAGAAGACTACAATGTGGATGAGATCGTGCAAAAGTTTTTGAACGCTTCCCATAAGCAGGCTGACTATTATAAGACAAACCACATCATCATGACCATGGGTTCAGACTTCCAGTATGAAAATGCCAATCTGTGGTATAAAAATATGGATAAGCTGATCAAGTATGTAAATGCACTGCAAGCCAAAGGGAGCAAGCTGAATGTGCTGTATTCGACACCGTCCTGCTACCTGCAGGAACTCAACCTGGCCAACTTCACCTGGCCTATGAAGACGGATGATTTTTTCCCATATGCTGATGATGCTCATGATTTCTGGACTGGCTACTTTACTAGCCGACCAGCGCTGAAGTTATATGAGAGACTTAGCAACAGCCGTCTACAGACATGCAACCAGCTGGAGGTGCTTGGAGGGCCCACATCTACATCAGGACCTTTTGGTGAAGGGGACAGTGATACTATGAGGCGGGCGATGGGTGTTGCCCAACATCATGATGCAGTGTCCGGGACAGAGAAACAGCATGTGGCAAATGACTATGCCAGGAGACTCGCTACAGGCTGGGCGCATTGTGAGGTGCTGGTTAGTAATTCTCTGGCTGTTCTCAGTGGTTCTGAAGCTCCACGTGTGTTCTGTGAAAATCTCAACATCAGTGTGTGTCCCCTCACAGAAAGCAGCCATAAGtTCTCTATGAATGTGTACAATCCTCTGGGCCGGACTGTAAGGTGGCCTGTTCGTTTGCCCGTAAATGGTTCAGTGTACAATGTTACTGATGCAAATGGGAAAGCAGTGGACAGTGAGGTCATTCCACTGTCTAAGTCCAGAAAGGAAGTGAGGCAGAACAGAGGTTTTGCTAAAAGTGAGCTGGTGTTCCAGGTTGAAGCTCCTCCTCTTGGTTACAGTACGTACATCATCTCCATGGTTCAGGATCAGCCTCCAGTATCTAGATCTAAAAATGCAGTCCCGTCCTCCATTCAAAACAAGTTCTTGAAGGTGACGTTTGACAGCACCACTGGTCTTTTGAGCAGCCTGACAAACCTGGAGACTCAACAAACTATTCGACTCACGCAAAACTTCTTTTGGTACAATGCAAGTGCTGGGAATAACAAGGAGAGCCATCAGCCATCTGGCGCTTATATCTTCAGACCAAACTCTTCAGACCCCTTCATCATCAGCAAGACTGCAGAAATCCAGGCGGTCTCACTATACAACAGTGTTCAGGAGGTGACGCAGCGGTTCAGCCCGTGGGTCTCTCAGGTGGTGCGTTTGTATGAGGACCGCAGGGAACTGGAGCTGGAGTGGACTGTAGGACCCGTGCCTGTTGAAGATGGTTTAGGGAAAGAAGTGATTACTCGTTTGGACACAGACATCCAGTCTTCTGGCTATTTTTACACTGATTCCAATGGCAGAGAAGTTCTGGAGCGACGGAAAGATTATCGGCCCACATGGGATTTGAAGCAGACCGAGCCAATTGCTGGAAACTACTATCCAATCAACTCTCGTGCTTACATCAAGgatgACAAGCGTCAGCTGACAGTGGTGACTGATCGTTCTCAAGGCGCCAGCAGCATTTATAACGGCTCACTGGAAATCatgCTGCACAGGAGACTTCTGTATGATGATTTCCGTGGTGTTGGAGAGCCTCTGTCTGAGCCGGGAGAGTTTGCTCATGGTTTAGTGGCTCGTGGTCGTCTCCTGCTGACCCTCAGTCCTCCAGAAGCAGCCGCTGACCTCCACAGACCACTCGCACAGTCCATGGTGCTCCAACCCCTGCTCTCCTTCCAGGACGGTGCTCCTTCCCCTGGCACTAAACTGGAGTTCTCTGGGCTTCAGGCTGCTCTGCCCCCTGCTGTTCATCTGCTGACAGTGTCACAGTGGGATCAGGATTCAGTTTTGGTCAGGCTGGAGCATCAGTACCAGGCTAAAGAGAGCAAAACACACTCGCAGCCTGTTACTGTCAACCTACAGAAGCTGTTTTCTACTCTGCAGGTGCTGGGAGCGTCTGAGATGAGTTTAGGAGCAAACCAGTGGAAAGAGGACATGATCCGCCTGCACTGGAACACTGATGCCCTTCCGCCCACTGCCAGAGATCCTTCATCATGGGAAGTGACACTAAAACCAATGGAAATCCGCACCTTCTTGTTACGAGTTCGGCTTCTGTAAGAACCAATCAAAATGCAGCATTGCAGTATCAAAACCCGTGGCactgatttgaaaaaaaatgatgtgtagattttttttttttttgcataatacaaTGAACTGATTCAGTGGACCAAAAATtaccaagtatttttttttttttatttcaaatttggaaATATTTCACACATCAATGtcatgttcataaaaaaaaaaaaaagatctacaaGAACTTTCGTAGCTATTAATTGTTCACCACTGATCTCCTGAGATTGATTTGTGCAATATTTTTCATGGTATTTTTCTACTGTGCCTTTCGTATGAATGAAAATGTCACTTAAAGAATAAACTgtggaataaataaatgtgtcctGTACATTA
>TCONS_00008071
GAGGGCAGTTTCATTTTCATCATGGCTTCGGAACCATGGCTTCACATCAGTCTTCtgctcttgttttgtttttcgcTTGTGTTTTCTTTGCCCACGGGTCGAAACTCCATCTGCGGTTATAAGTCATGTCCAGCCACAAAGCCATCCATGCTGAACGTCCATCTGGTTCCACACACACATGATGATGTCGGCTGGCTCAAGACTGTGGATCAGTACTTTTACGGAGaccGAAATAACATCCAGCATGCAGGTGTTCAGTATATTCTGGACTCAGTGATCGATCAGCTACAGAAGGATCCAGCTCGACGCTTTATCTATGTTGAGACGGCCTTCTTTTACCGCTGGTGGAGACAGCAGAACCAGAACACACGCCGCATTGTGACCCAGCTGGTCAATGAGGGTCGTCTTGAGTTCATAAATGGTGGCTGGTGCATGAGCGATGAGGCGACCACACACTACAGCGCTGTCATTGATCAGATGACTCTGGGGCTGCGATTCCTCAATGACACTTTCGGCGAGTGTGGACGTCCCCGGGTGGCTTGGCACATTGACCCCTTCGGACACGCCAGAGAACACGCCTCCATCTTTGCTCAGATGGGCTATGACGGCTTCTTCTTTGGCCGCTTGGACTACCAGGACAAGGACCGCAGGATGAAGACCAAAGAGATGGAAATGCTCTGGAGGGCCAGTGAGAGCCTGACTCCACCTATTGCCGATCTCTTCACAGGTCATCTTGAGTTCATAAATGGGGGCTGGTGCATGAGCGATGAGGCGACCACACACTACAGCGCTGTTATATaactttgttatattttttaagttttataaacCTTGTATAATTTAGAAACATTAGCTAAAACCttattaacttaataaaataagttaaagtgaCTTAAAA

Function

symbol description
man2b1 Predicted to enable alpha-mannosidase activity. Predicted to act upstream of or within mannose metabolic process. Predicted to be active in lysosome and vacuolar membrane. Human ortholog(s) of this gene implicated in alpha-mannosidosis. Orthologous to human MAN2B1 (mannosidase alpha class 2B member 1).

GO:

id name namespace
GO:0008152 metabolic process biological_process
GO:0005975 carbohydrate metabolic process biological_process
GO:0006013 mannose metabolic process biological_process
GO:0005764 lysosome cellular_component
GO:0005774 vacuolar membrane cellular_component
GO:0046872 metal ion binding molecular_function
GO:0004559 alpha-mannosidase activity molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0016798 hydrolase activity, acting on glycosyl bonds molecular_function
GO:0030246 carbohydrate binding molecular_function
GO:0003824 catalytic activity molecular_function

KEGG:

id description
ko00511 Other glycan degradation
ko04142 Lysosome

ZFIN:

id description
ZDB-GENE-050327-52 Predicted to enable alpha-mannosidase activity. Predicted to act upstream of or within mannose metabolic process. Predicted to be active in lysosome and vacuolar membrane. Human ortholog(s) of this gene implicated in alpha-mannosidosis. Orthologous to human MAN2B1 (mannosidase alpha class 2B member 1).

Ensembl:

ensembl_id ENSDARG00000001897

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00008070 False 3346 mRNA 0.48 22 31258116 31276080
TCONS_00008071 True 898 mRNA 0.48 6 31272649 31276064

Neighbor

gene id symbol gene type direction distance location
XLOC_004213 nacc1b coding downstream 23532 31218956 ~ 31234584 (-)
XLOC_004212 NA coding downstream 46808 31204925 ~ 31211308 (-)
XLOC_004211 NA coding downstream 55277 31200219 ~ 31202839 (-)
XLOC_004210 si:dkey-238i5.3 coding downstream 85840 31168697 ~ 31172276 (-)
XLOC_004209 si:cabz01069582.1 coding downstream 111308 31144720 ~ 31146808 (-)
XLOC_004215 AL844172.2 coding upstream 592940 31869020 ~ 31872628 (-)
XLOC_004216 NA coding upstream 874138 32150218 ~ 32157526 (-)
XLOC_004217 NA coding upstream 1089832 32365912 ~ 32391388 (-)
XLOC_004218 NA coding upstream 1181236 32457316 ~ 32563722 (-)
XLOC_004219 NA coding upstream 1196703 32472783 ~ 32473383 (-)
XLOC_004063 CR854846.1 misc downstream 15130438 16127382 ~ 16127678 (-)
XLOC_004019 CR450764.8 misc downstream 18566425 12691395 ~ 12691691 (-)
XLOC_004015 CR450764.4 misc downstream 18636349 12621518 ~ 12621767 (-)
XLOC_004013 CABZ01022569.1 misc downstream 18666820 12590999 ~ 12591296 (-)
XLOC_004008 BX000700.19 misc downstream 18744854 12512966 ~ 12513262 (-)
XLOC_004200 CR318645.1 non-coding downstream 1156859 30101142 ~ 30101257 (-)
XLOC_004198 CU652893.1 non-coding downstream 1296215 29961114 ~ 29961901 (-)
XLOC_004193 NA non-coding downstream 1520869 29734578 ~ 29737247 (-)
XLOC_004221 BX000696.1 non-coding upstream 1455085 32731165 ~ 32737593 (-)

Expression


Co-expression Network