XLOC_004262 (brk1)


Basic Information

Item Value
gene id XLOC_004262
gene name brk1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007122.7
NCBI id CM002895.2
chromosome length 45484837
location 36041617 ~ 36156971 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00008139
aaaatgtaGTAACAGTTtttctattttggtgaaaacttggcaaggttgacatttgcatggaattgctcatatataggcTAATGCAACAAATAATGTCGccattaatacatttttagaatCAGGTTTGTTAACAAATACTATTTAACGATGTAAGTTTATTTGTGCAGGCTTAACACTAGTGACAAATAACCCAGATTTGGTGTTTCGGTGTGTGTCCATCAGGGGTCGCTGCTTTTTCTCCTATCGCAAACAGCGGCggctaatgctaatgctaactAGCTCACGATGGCCGGACAGGAGGATCCAGTGCAAAGGGAGATTCACCAAGATTGGGCAAATCGAGAATACATCGAAGTGATCACCAGCAGCATTAAGAAAATAGCCGATTTCCTCAATTCCTTCGATATGTCCTGCAGGTCTCGTTTAGCCACTTTGAATGAGAAGCTCACTGCTTTGGAGAGGAGGATCGAGTACATCGAAGCCAGAGTCACAAAAGGGGAAACCCTGACTTAGGCACATTCCTGGCATCGATGCTGAGGTCAAGATAATGGCTACGAACACGCACCTCCTGTCTtcatcatttactttaattagtCAAACAAAATTTCCATTCGTTGGCTGTTTCAGATCAGTTCATTTTTGTATGGGACCATTGTGATGCTGTAAACAGATATTTGCTTTCCTCATTTCATGCCTGATTGTGGCTGAAGTTATACTGTATCTGGTCCTTTAATTTTATTGACCTTTTTTTGATCTGTCAGGCAACTTGTTACTGTCTCTGTGGTGCTTGCTTTCGCAAACATCCCAGTGTTGTATGTTGTTTGGGTTTGACCTGCTAGTGAACTTACTTTTGACGTACCATGCAATATATATATCAACAGTCTTGCAATTGCAGACTGGAGTTACCATGGATAAACATTATGCCttgctttaattttaattattgataGCTAATATTTTGTTtgatcccccccccccctttttctTTGCGTTTTTACCAGGGTCTAAACTGTTATTGTTTAATtacaaaggtgtgtgtgtgtgtgtttaaaatacaCTGCTTCCTGCTGTACATTTGTCATGCAACAAACATCTGCACATGAGAAATGCCAGTCAGGTGGATGGAAAGCACTAAAGTGCCAATCAGACTGTTTTAAAGTGTTTAGTGCTTCTCCAATTATACAATTTTATGTCGTAGTGTCTGTTATAATGTTTTTGTGgttgaacattaaataaaaaagttaaaggaTTCTGATTATTTTCTTTTAGTATTTATTggtgttttcaacattttaacaAATGCAAAACAgtataaatgatataaataaataaattttatttttataaatgtgtatatttattaattatgtgagtatatagatatatatttgtgtgtgtgtgtgtgtgtgtacatatgtatacgtgtgtgtgtgtgtgtgtgtatacacacacacacatatacatacaatatTGGAATAATGCATTGCAAGTAACTTAAAGTTACATCGTAATATTACCTTTCTAAGTaacgattttaaaaagtagtaaTATTTGAGTTGCCTTTTAGTTTAACTAatgagcttttaaaaaataaattgctgaaaatTAAACACAATGAATTGCACAGTCAATGAgggaatgtgttcattattttcaaCGCATCGAAGAAAAGTATTGTTTcgatggacagtgattttacttaagacaaatagtactAAAGTAGAGAACACATtcctttaaactttcattaatctatatatggcatgtatagctctggggtcaggaagttctcagataacatcctaaaaaaaaaaaaaaaaaaaaaaaaaatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatata
>TCONS_00008140
CTTCGGAAATTGGACATGCACTGTCTCTAAAGTGATAGAGTAGTAAAATCAGAAGTAAAGTTACTTCTGGGATACTTCGAGATCATTTTGAGGCCAGATTTGGACAGGCCACAAACTTTAAACAGCGAAGATAACAAGTGGTGTGTGAGTGTGACTGGTTGTGTTTTCCGCCTGTTGCGAGGGCTGGAAGAGTGTGTTCGCACCTGTCCGAATCCAGCTCCAGCTCCTCGAAGGAAGAGACGCTGGAGGTGTCGCTTCTCTCCACACGATCGAAGTCCCAGTATTGCTGTCTGTCCGGGTGCGAGTGTGTCCGCGTGCTGGACGGGGCAGGTGAAGCGTCCTGCTGGCTCACAGAAGAACTGCGCTCGCTGTTGGAATCAGCACCTGGGTCGCTGCTTTTTCTCCTATCGCAAACAGCGGCggctaatgctaatgctaactAGCTCACGATGGCCGGACAGGAGGATCCAGTGCAAAGGGAGATTCACCAAGATTGGGCAAATCGAGAATACATCGAAGTGATCACCAGCAGCATTAAGAAAATAGCCGATTTCCTCAATTCCTTCGATATGTCCTGCAGGTCTCGTTTAGCCACTTTGAATGAGAAGCTCACTGCTTTGGAGAGGAGGATCGAGTACATCGAAGCCAGAGTCACAAAAGGGGAAACCCTGACTTAGGCACATTCCTGGCATCGATGCTGAGGTCAAGATAATGGCTACGAACACGCACCTCCTGTCTtcatcatttactttaattagtCAAACAAAATTTCCATTCGTTGGCTGTTTCAGATCAGTTCATTTTTGTATGGGACCATTGTGATGCTGTAAACAGATATTTGCTTTCCTCATTTCATGCCTGATTGTGGCTGAAGTTATACTGTATCTGGTCCTTTAATTTTATTGACCTTTTTTTGATCTGTCAGGCAACTTGTTACTGTCTCTGTGGTGCTTGCTTTCGCAAACATCCCAGTGTTGTATGTTGTTTGGGTTTGACCTGCTAGTGAACTTACTTTTGACGTACCATGCAATATATATATCAACAGTCTTGCAATTGCAGACTGGAGTTACCATGGATAAACATTATGCCttgctttaattttaattattgataGCTAATATTTTGTTtgatcccccccccccctttttctTTGCGTTTTTACCAGGGTCTAAACTGTTATTGTTTAATtacaaaggtgtgtgtgtgtgtgtttaaaatacaCTGCTTCCTGCTGTACATTTGTCATGCAACAAACATCTGCACATGAGAAATGCCAGTCAGGTGGATGGAAAGCACTAAAGTGCCAATCAGACTGTTTTAAAGTGTTTAGTGCTTCTCCAATTATACAATTTTATGTCGTAGTGTCTGTTATAATGTTTTTGTGgttgaacattaaataaaaaagttaaaggaT
>TCONS_00008141
CGATGGCCGGACAGGAGGATCCAGTGCAAAGGGAGATTCACCAAGATTGGGCAAATCGAGAATACATCGAAGTGATCACCAGCAGCATTAAGAAAATAGCCGATTTCCTCAATTCCTTCGATATGTCCTGCAGGTCTCGTTTAGCCACTTTGAATGAGAAGCTCACTGCTTTGGAGAGGAGGATCGAGTACATCGAAGCCAGAGTATGTTTTCATGGAtttcataaatacattttcaggtttattttgttttaaataacccTCATTTTAACTACTGCTTGATGTTTTAAGGTCACAAAAGGGGAAACCCTGACTTAGGCACATTCCTGGCATCGATGCTGAGGTCAAGATAATGGCTACGAACACGCACCTCCTGTCTtcatcatttactttaattagtCAAACAAAATTTCCATTCGTTGGCTGTTTCAGATCAGTTCATTTTTGTATGGGACCATTGTGATGCTGTAAACAGATATTTGCTTTCCTCATTTCATGCCTGATTGTGGCTGAAGTTATACTGTATCTGGTCCTTTAATTTTATTGACCTTTTTTTGATCTGTCAGGCAACTTGTTACTGTCTCTGTGGTGCTTGCTTTCGCAAACATCCCAGTGTTGTATGTTGTTTGGGTTTGACCTGCTAGTGAACTTACTTTTGACGTACCATGCAATATATATATCAACAGTCTTGCAATTGCAGACTGGAGTTACCATGGATAAACATTATGCCttgctttaattttaattattgataGCTAATATTTTGTTtgatcccccccccccctttttctTTGCGTTTTTACCAGGGTCTAAACTGTTATTGTTTAATtacaaaggtgtgtgtgtgtgtgtttaaaatacaCTGCTTCCTGCTGTACA
>TCONS_00008142
AACATGCACTTCCTTGACGCATTTTTACGCGCCTCCTATTTTCGGCTTCAAGGTTCAAATCAAGGATCTTGACGGTAAATAAAACCTGCGTGTTGCCCTTTGAGCTGCAGAGAAAACTGCGTGTTCGAGCATGGCAGGAACCATGAAGAAGTTTTACGACCTGTCCGCGAAACTATTGTCAGGAGATCTCCTGAATTTTTCCTCTCTCAAAGGAAAGGTTGTGCTGATTGAAAATGTGGCGTCGCTTTGAGGCACAACAGTCAGGGATTACACCCAGATGAACGAGCTCCACAGCCGGTACGCCGACCAGGGGCTGGTGGTTCTGGGCGCTCCCTGCAACCAGTTCGGGCACCAGGAGAACTGCAAGAATGAAGAAATCCTGCAGTCTCTGAAATACGTCCGTCCTGGAAATGGCTTCGAGCCCAAATTCCAAATTCTGGAGAAGCTGGAAGTGAATGGTGAAAACGCCCACCCTCTGTTTGCGTTCCTGAAGGAGAAGCTTCCTCAGCCCAGTGACGACCCTGTGTCCCTTATGGGAGACCCTAAATTTATCATCTGGAGCCCCGTGTGCAGGAATGACATCTCCTGGAACTTTGAAAAGTTCCTCATCGGGCCGGACGGGGAACCATTCAAGAGGTACAGCAGAAGGTTCCTCACCATCGACATTGATGCTGATATTAAAGAGCTTCTGAAGAGAACCAAGTAAACCAGCGGCTTCTACGTGTTGTGTTCTTGCAAGATAAACCGTCCACTGCACATcacatgctttaaaaataagattGTAGTTTGATATAGACCGACTGTGCAGTCATGATTAAAGTGCCACTGCTTTCTACACTGTTTACTTAATGAAGATGCTTCCTAAAACCTTTTCTGAGGGGAGTTTCTGATGgactgtaaatgtttattatagcTGTTGTAAGTTATGCATGAACTGCACGGCTCAGGTTTTATCATTCCACTCTGTGAactgaaaataaactttttaaacaaa
>TCONS_00008143
GCATGCTGTCGGAATGGTCTTAAATCCGCGTTTATTCTTCGGAAATTGGACATGCACTGTCTCTAAAGTGATAGAGTAGTAAAATCAGAAGTAAAGTTACTTCTGGGATACTTCGAGATCATTTTGAGGCCAGATTTGGACAGGCCACAAACTTTAAACAGCGAAGATAACAAGTGGTGTGTGAGTGTGACTGGTTGTGTTTTCCGCCTGTTGCGAGGGCTGGAAGAGTGTGTTCGCACCTGTCCGAATCCAGCTCCAGCTCCTCGAAGGAAGAGACGCTGGAGGTGTCGCTTCTCTCCACACGATCGAAGTCCCAGTATTGCTGTCTGTCCGGGTGCGAGTGTGTCCGCGTGCTGGACGGGGCAGGTGAAGCGTCCTGCTGGCTCACAGAAGAACTGCGCTCGCTGTTGGAATCAGCACCTGAAAGGTTGTGCTGATTGAAAATGTGGCGTCGCTTTGAGGCACAACAGTCAGGGATTACACCCAGATGAACGAGCTCCACAGCCGGTACGCCGACCAGGGGCTGGTGGTTCTGGGCGCTCCCTGCAACCAGTTCGGGCACCAGGAGAACTGCAAGAATGAAGAAATCCTGCAGTCTCTGAAATACGTCCGTCCTGGAAATGGCTTCGAGCCCAAATTCCAAATTCTGGAGAAGCTGGAAGTGAATGGTGAAAACGCCCACCCTCTGTTTGCGTTCCTGAAGGAGAAGCTTCCTCAGCCCAGTGACGACCCTGTGTCCCTTATGGGAGACCCTAAATTTATCATCTGGAGCCCCGTGTGCAGGAATGACATCTCCTGGAACTTTGAAAAGTTCCTCATCGGGCCGGACGGGGAACCATTCAAGAGGTACAGCAGAAGGTTCCTCACCATCGACATTGATGCTGATATTAAAGAGCT

Function

symbol description
brk1 Predicted to be involved in cell motility and regulation of actin polymerization or depolymerization. Predicted to act upstream of or within actin filament organization. Predicted to be located in cytoplasm and cytoskeleton. Predicted to be part of SCAR complex. Orthologous to human BRK1 (BRICK1 subunit of SCAR/WAVE actin nucleating complex).

GO:

id name namespace
GO:0007015 actin filament organization biological_process
GO:0048870 cell motility biological_process
GO:0008064 regulation of actin polymerization or depolymerization biological_process
GO:0005856 cytoskeleton cellular_component
GO:0031209 SCAR complex cellular_component
GO:0005737 cytoplasm cellular_component
GO:0044877 protein-containing complex binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040625-77 Predicted to be involved in cell motility and regulation of actin polymerization or depolymerization. Predicted to act upstream of or within actin filament organization. Predicted to be located in cytoplasm and cytoskeleton. Predicted to be part of SCAR complex. Orthologous to human BRK1 (BRICK1 subunit of SCAR/WAVE actin nucleating complex).
ZDB-GENE-030410-1 Predicted to enable glutathione peroxidase activity. Predicted to be involved in several processes, including glutathione metabolic process; hydrogen peroxide catabolic process; and response to selenium ion. Predicted to act upstream of or within response to oxidative stress. Predicted to be active in cytosol and mitochondrion. Is expressed in Kupffer's vesicle; digestive system; muscle; optic tectum; and sensory system. Human ortholog(s) of this gene implicated in several diseases, including anemia (multiple); cardiovascular system disease (multiple); hematologic cancer (multiple); nutritional deficiency disease (multiple); and pseudoxanthoma elasticum. Orthologous to human GPX1 (glutathione peroxidase 1) and GPX2 (glutathione peroxidase 2).

Ensembl:

ensembl_id ENSDARG00000018146 ENSDARG00000041974

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00008139 False 1902 mRNA 0.34 3 36041617 36046741
TCONS_00008140 False 1414 mRNA 0.43 5 36042269 36156935
TCONS_00008141 False 878 mRNA 0.39 2 36042445 36046458
TCONS_00008142 False 994 mRNA 0.46 2 36048579 36051004
TCONS_00008143 True 897 mRNA 0.52 4 36048886 36156971

Neighbor

gene id symbol gene type direction distance location
XLOC_004261 setmar coding downstream 1068 36037076 ~ 36040549 (-)
XLOC_004260 itpr1b coding downstream 21612 35777329 ~ 36020005 (-)
XLOC_004259 bhlhe40 coding downstream 278294 35759652 ~ 35763323 (-)
XLOC_004258 arl8bb coding downstream 285149 35744918 ~ 35756468 (-)
XLOC_004257 NA coding downstream 300173 35578730 ~ 35741444 (-)
XLOC_004263 rrp9 coding upstream 58727 36215698 ~ 36230163 (-)
XLOC_004264 NA coding upstream 85088 36242059 ~ 36246756 (-)
XLOC_004265 nfya coding upstream 97313 36254284 ~ 36279664 (-)
XLOC_004266 sort1a coding upstream 123552 36280523 ~ 36341189 (-)
XLOC_004267 psma5 coding upstream 186026 36342997 ~ 36350993 (-)
XLOC_004063 CR854846.1 misc downstream 19913939 16127382 ~ 16127678 (-)
XLOC_004019 CR450764.8 misc downstream 23349926 12691395 ~ 12691691 (-)
XLOC_004015 CR450764.4 misc downstream 23419850 12621518 ~ 12621767 (-)
XLOC_004013 CABZ01022569.1 misc downstream 23450321 12590999 ~ 12591296 (-)
XLOC_004008 BX000700.19 misc downstream 23528355 12512966 ~ 12513262 (-)
XLOC_004255 NA non-coding downstream 600200 35438013 ~ 35441417 (-)
XLOC_004254 BX293991.1 non-coding downstream 816478 35225022 ~ 35225139 (-)
XLOC_004249 NA non-coding downstream 1464511 34550847 ~ 34577106 (-)
XLOC_004247 BX548160.2 non-coding downstream 1575104 34466395 ~ 34466513 (-)
XLOC_004269 NA non-coding upstream 327421 36484392 ~ 36687161 (-)
XLOC_004270 NA non-coding upstream 411953 36568924 ~ 36569266 (-)
XLOC_004271 CR457444.8 non-coding upstream 463746 36620717 ~ 36627322 (-)
XLOC_004274 BX248521.2 non-coding upstream 853190 37010161 ~ 37015507 (-)

Expression


Co-expression Network