XLOC_004322 (tnfrsf1b)


Basic Information

Item Value
gene id XLOC_004322
gene name tnfrsf1b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007122.7
NCBI id CM002895.2
chromosome length 45484837
location 40431629 ~ 40457325 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00008225
GTCACTTTATCTATTTGTCCGTCGCAATTATTTAGCCTTTTACATTTGAGTGATATCCCCTAACATTGTTTAGACAAAATAATTAGAGGACTGgacttaaatatataaataaatacagtttgtgCACGCGCGGACTTCAGAGGTCCGGGTCTGACGCATTGCCACTGCTTCCTGTATTTCACCATTTCCGAGACGCGAATCATGCGAGAGTGATGGTCAGTGAGTCGCGCGGGTCTCTGAAGGATCATGTTGATTTTAATCGCAcggttattgttgttatttatgacGGTGGTGTGGCTCATGGCGGAAGGAAAGATTCCTCCGCCATTTAGACCTGAAAAAGAACAATGTAATAACACCACCTCTGAATATTACATGAAACAACTGGGACTTTGCTGCAGTAGATGCAAACCAGGGACTCGCTTGTCTGTGCAATGCAGTACTGCTTCGGACACCATTTGTGAACCCTGCCCAGATGGAATGTACTCAGAGAATATGAACCATTATCCCAATTGTTTCAAGTGTCCAACATGTAGAGAAGAGAAAGGACTGATGTACGGCAGGAACTGCTCCGCTGATACCAAAGCTGTCTGTGTTTGCAAGCCTGGAATGTACTGTTCGAAGTATGGTTTGTCATCTGCATGTGAGgaatgtaaaaaatacaaaacctGCAAACCCGGCGAAGGCGCTCAAAGAAAAGgaaCACCTACAGGTGTTGTGAAGTGTGCACCGTGTCCAACTGGGACGTTTTCAGACCGCAGTGGCTCTGAGCCATGCAGACCACACACCGAatGTGAAGGTAGTGCAGTTTTAAGGTCTGGCAACTCTACAGATGACACAGTTTGTGTAGTGAAACCATTAAAAGCAACGCCGGAAATATGGCCCATGAATACTATCAGCACATCGACTGTTTCTGTATTGAGCAGCGACgtcaaacacagcagcacagtgacgACAAACGCACAAGGGACCCGAAGCAACCCTCCGCCTGACTACATGACCATCATCTACATcactgGTGCTGTTGTGCTGGTTTTGCTGATTCTGGTTATGACGGTGGTTACTTGCAAGTTACGAGAACGAAAAGGTTTAACAAAAGTTCCCATCACAGATGTCAACACGGTGGAGCAGGATCCCTCACAGAGCAGCACACCTGACCATCAGCATCTGTTACATGTGGACAGAACCCAGACGGAGCCGTCCATGAGCTCGTCAGACAGTCAGAGTCAGCCGGACTGCGGTCAGAGCCACAGCAGCAGTGAGTGGCTGGAGCGCAGCAGTCAGGACGAATGTCCGTCCGTCTCCAGCCCTGTGCTCAATCTCAGCATCACGGCCACATTCAACTGCCAGCTCAACCCGGCCGCGACGTCCTGCTCCATCCCCATCAACCCGTCCACTTTGACGCCACACGCCGAAGCCCTGGTGCCGCTTTCTCAAGAGGAGGTCTGTACATCATCCTGCCAACAAGAGGACGGCAAAGAAGTGCTGAAGTCGGTGCAGGAGAGTGGCCCGTTCCTATACTGAACATCACACGCTTCCATTCACATCAATGCATTTGCTTTAAACATGTTGTATTGTATGGGCTGAAACACACCAAGCTGACACCAAACAACTAGCATTGCAAGAGGATGTGTTTTCTTCTCTGCAGAGGGCAGTGTGTGTTTTCTCATTCCACAATGGGAAACTGAACGTCTGACGTGCACAGTCGAAGAGTAAACAGAGCAGTGTTATCACAGTAATGGTCACTCAACACGAAGGGATTCGCTCATGCAAATATATCTGACAATCTAATAATTCGtatcatttacaaatatttgagACATATACTGAAGTTACAGCCGGCctctttgtgtttctttttgacttgaattgtttacttgctgTGTCACTTCATTACTTCACACCCGCGCTCTGATTTCCTTCAGCTGACGCCGATTTGCCATGCTGAATTGAACCAACGAGCTCCGATGTTAACCCGACGGGTCGGAACACACCAAGCTGATGCCAAACAGCTAGCACAAATGAAACATAACTGTGTTGTTGCCTTTTGTTGGATCGCATCTGGACCAAAAAcctgcatgtaaatgcatcaaacaCACCAAAGTCTAGTAAAACCAGAGCCTCGTTCTGTGCCTAGAACGAGTAGTAGGCCAGTAGTAACGCCAGTAGGAGGCAGTGTCGGTTTTCTTGTTCTGCAAAGGGAAACTTAACTTTCAACGTGCTCAGCcaaagtgtaaacaaagcagcgttcAGTACCATTATTACAGAAGTTGTCACTCAACACAGAGGGATTCACTCATGCAAATATGTTTGATAATTCACATCGTTTGCAAGAAATGTGTGAAATATAGCGAAATTACGGCCtctttgtgatgtttttttggCTTGAAATGTTTACTCGCTTCGTCACTTCCCTATGTCACACTCATGGtctgatttattttttgaataaCCCGTAAGAGTGGTCTCCTGCCCACAGTGATTTGACTTGGCCAAAGAGCCTTCTAGGTTAACCCCATGGGCGGGTACACACCAACCCAATGCCAAACTGCTAGTGAAAAACCAAACCCAACTGTGTTGTCACATCTGGACCAAAAAACAGCTCGTGACCACACCAAACGGATGATTGGACATGCTGAATTGGACCAActgggacacaccaagccaaCGCCAAAAAACTAGCACCAACTAAATCTGTGTGTTTGCCTCGCATTAGATTatgtctggaccaaaaagctgtgtgtgaacacaccaaacaaaGGATTGGACATGCTGAATTGTGCCAACCGGGACACGCCAAGCTGACGGCAAACAACTAGCACCAATGAAACCGAACTGTTGTTGCCTCGTGTTGGATTGCGTCTGGACCAAAAAACAGCTCGTGACCACACCAAACGGATGATTGGACATGATAAATTGGCCCAACCAGGACACACCAAGCTAACGCCAAAAAACTAGCACCAACTAAATCTGTGTTTTCGCCTCGCATTAGATTacatctggaccaaaaagctgttCGTGACCACACCAAACGAATGATTGGACTTGCTGAATTGGGCCAACCGGGACAAACCAAGCCGACACCAAACAACTAGCGCCAATGAAACCGAACTGTTGTCGCCTCGTGTTGGATCACGTCTGGACCAAAAAACTGTTTGTGACCACACCAAACGGATGATTGGACATGCTGAATTGGGCCAACCGGGACACAGCAAGCTGATGCCAAACAAGCAGCACCAATGAAGCTCTGTTGTCTCCTCACGTTGGATTGCGTCTGGACAAAAAATCTGTgtgtgaacacaccaaacaaaaAGCAGACTCAAAGAAGAACCATGTTCTGCACCTGTGCAAGAATACGTGTCTTTCCGCTCCGCAGGGGGCAGCAGGGTCAGTTTTCTTGAACTTCTGCACACACagacagtgtaaacaaagcagtgttaAGCTCCATTATCACTGTAATTGCCGCTGGATTCGCTTGTGCAAATATTTCTCAAACTTGataatgtctttattttcttttttcacttgAATTCTTTACTTGCTACGTCACTTCTCTACGTCACAGTCGCGCTAAATAACCAATCAGAGTGCTCTCTTCTGCTAATGCCCATTCGACATGATGAATTGCTCTAATGTTAACCTGTTGTGAGGCGATGTGTGGGTCACCAAACCAACTCCCCGGACTGACAAAGCTCAACAGCCGACAAATGGCTTGGTGTGTCCTGTCATTGTAAAATAGTATGCCATGTAAATAAGTGTTTTATAACCATTTCATGTCTTAATGATACGGTTTACTTAAAACTGACCGTTTACTCACACTCAAATAGTTCAATGGATGTCTTTTATGCATTCTTCAGTATGTTTTCCCCTGTATTCAACATAAGACATAAACtcaagcaggtttggaacaagagtaaatgatgatggaaggttaa

Function

symbol description
tnfrsf1b Acts upstream of or within several processes, including peripheral nervous system axon ensheathment; positive regulation of hematopoietic progenitor cell differentiation; and regulation of cysteine-type endopeptidase activity involved in apoptotic process. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including head; head mesenchyme; hematopoietic system; osteoclast; and scale. Used to study psoriasis. Human ortholog(s) of this gene implicated in several diseases, including Parkinsonism; acne; bone disease (multiple); glomerulonephritis (multiple); and lung disease (multiple). Orthologous to human TNFRSF1B (TNF receptor superfamily member 1B).

GO:

id name namespace
GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process biological_process
GO:1901532 regulation of hematopoietic progenitor cell differentiation biological_process
GO:1901534 positive regulation of hematopoietic progenitor cell differentiation biological_process
GO:0009615 response to virus biological_process
GO:0001944 vasculature development biological_process
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component

KEGG:

id description
ko04668 TNF signaling pathway
ko04060 Cytokine-cytokine receptor interaction
ko04061 Viral protein interaction with cytokine and cytokine receptor
ko04920 Adipocytokine signaling pathway
ko05170 Human immunodeficiency virus 1 infection
ko05014 Amyotrophic lateral sclerosis
ko05022 Pathways of neurodegeneration - multiple diseases
ko04050 Cytokine receptors
ko04090 CD molecules

ZFIN:

id description
ZDB-GENE-070410-133 Acts upstream of or within several processes, including peripheral nervous system axon ensheathment; positive regulation of hematopoietic progenitor cell differentiation; and regulation of cysteine-type endopeptidase activity involved in apoptotic process. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including head; head mesenchyme; hematopoietic system; osteoclast; and scale. Used to study psoriasis. Human ortholog(s) of this gene implicated in several diseases, including Parkinsonism; acne; bone disease (multiple); glomerulonephritis (multiple); and lung disease (multiple). Orthologous to human TNFRSF1B (TNF receptor superfamily member 1B).

Ensembl:

ensembl_id ENSDARG00000070165

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00008225 True 3935 mRNA 0.46 9 40431629 40457325

Neighbor

gene id symbol gene type direction distance location
XLOC_004321 trim62.1 coding downstream 12654 40331791 ~ 40418975 (-)
XLOC_004320 trim62.2 coding downstream 174404 40227753 ~ 40257225 (-)
XLOC_004318 znf362a coding downstream 227008 40175161 ~ 40204621 (-)
XLOC_004319 CT033813.1 coding downstream 248833 40182681 ~ 40182796 (-)
XLOC_004317 EMP3 coding downstream 259334 40134856 ~ 40172295 (-)
XLOC_004323 NA coding upstream 3526 40460851 ~ 40462487 (-)
XLOC_004324 si:dkeyp-61b2.1 coding upstream 10293 40467618 ~ 40504170 (-)
XLOC_004325 miip coding upstream 47719 40505044 ~ 40519886 (-)
XLOC_004326 prxl2b coding upstream 164985 40622310 ~ 40647237 (-)
XLOC_004327 si:ch211-222l21.1 coding upstream 220291 40677616 ~ 40696136 (-)
XLOC_004063 CR854846.1 misc downstream 24303951 16127382 ~ 16127678 (-)
XLOC_004019 CR450764.8 misc downstream 27739938 12691395 ~ 12691691 (-)
XLOC_004015 CR450764.4 misc downstream 27809862 12621518 ~ 12621767 (-)
XLOC_004013 CABZ01022569.1 misc downstream 27840333 12590999 ~ 12591296 (-)
XLOC_004008 BX000700.19 misc downstream 27918367 12512966 ~ 12513262 (-)
XLOC_004313 CR847998.1 non-coding downstream 786319 39637740 ~ 39645310 (-)
XLOC_004312 NA non-coding downstream 1126466 39303597 ~ 39305163 (-)
XLOC_004311 NA non-coding downstream 1218864 39208184 ~ 39212765 (-)
XLOC_004308 CU210919.2 non-coding downstream 1341638 39089875 ~ 39089991 (-)
XLOC_004330 FP236327.1 non-coding upstream 303393 40760718 ~ 40761318 (-)
XLOC_004331 CABZ01083815.1 non-coding upstream 401329 40858654 ~ 40860470 (-)
XLOC_004332 CABZ01044765.1 non-coding upstream 436441 40893766 ~ 40895245 (-)
XLOC_004333 NA non-coding upstream 491564 40948889 ~ 40949818 (-)

Expression


Co-expression Network