XLOC_004382 (clcn4)


Basic Information

Item Value
gene id XLOC_004382
gene name clcn4
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007122.7
NCBI id CM002895.2
chromosome length 45484837
location 44144612 ~ 44163164 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00008296
CTGTATGTCGACGTCCTGCCGCATCAGTTTATTCTGATGTTATGATGGATAAACACTACTATATATCACCGTATATCTGATTTAATTACACACACGACGACATGGCGGAGGCTGAGGGCATCAGCAGTGCGACTCCCACTGAGGAGATGAACGGCGCCGGGAACCTGATGGACTTCTTAGATGAACCATTTCCAGATGTTGGCACTTATGAGGACTTTCACACCATCGACTGGCTCCGAGAGAAGTCcaaagacacagacagacaccGCAAGATCACCAGTAAGAGTAAAGAGTCCATCtgggagttcatcaagagtctgcTGGACGCCTGGTCAGGGTGGCTGGTGATGCTCCTGATTGGCCTGCTGTCAGGCACTCTGGCCGGAGTGATCGATCTGGCTGTTGATTGGATGACGGATCTGAAGGAAGGCGTGTGTTTATCTGCGTTCTGGTACAGTCATGAGCAGTGCTGCTGGACGTCCAACGAAACCACCTTCGCTGACAGAGACAAATGTCCACAGTGGCAGAAATGGGCTGAGCTGATGACCGGATACACAGAGggcgCTGGTGTGTATGTGCTGAACTACTTCCTGTACGTGCTGTGGGCTCTGTTCTTCTCCTTCCTGGCCGTGTCTCTGGTGCGAGTGTTTGCTCCGTACGCCTGCGGTTCAGGAATACCAgagaTCAAGACCATCCTGAGCGGCTTCATCATCCGTGGGTATCTGGGCAAGTGGACGCTGCTGATCAAGACGGTGACGCTGGTTCTGGCCGTGTCTTCAGGCCTCAGTCTGGGGAAGGAGGGTCCGCTGGTCCACGTGGCCTGCTGCTGTGGAAACCTCTTCTGCAGCCTCTTCTCCAAGTACAGCAAGAATGAAGGCAAACGCAGAGAGGTGCTGTCAGCTGCAGCGGCCGCTGGTGTCTCAGTGGCATTTGGAGCTCCGATTGGAGGAGTACTGTTCAGCTTGGAGGAGGTCAGCTATTATTTCCCTCTGAAGACTCTCTGGCGCTCGTTTTTCGCCGCTCTGGTCGCCGCCTTCACCCTGCGCTCCATCAACCCATTTGGGAACAACCGCCTGGTGCTGTTCTACGTGGAGTACCACACACCCTGGTACATGGCAGAGCTGGTGCCCTTCATCCTGCTGGGGGTGTTCGGAGGCCTTTGGGGGACACTGTTTATCCGCTGCAACATCGCCTGGTGCCGCCGCCGCAAAACCACCCGCCTGGGCAAATACCCGGTGCTGGAAGTGCTGGCGGTGACGGGCATCACTGCGGTGCTGGCCTTCCCGAATCCGTACACTCGCCGCAGCACCAGCGAGCTGATCTCAGAGCTGTTCAATGACTGCGGAGCGCTGGAGTCCTCGCAGCTCTGTGATTACATCAACAGCCCCAACATGACCCGCCCGGTGGACGATATTCCTGACCGACCCGCAGGGCCTGGGGTCTACAGCGCCCTCTGGCAGCTCACACTCGCACTTGCCTTTAAGATCATCATCACCATCTTCACCTTCGGCATGAAGATCCCGTCGGGTCTGTTCATCCCCAGTATGGCAGTGGGTGCGATTGCGGGCCGTATTGTTGGTATCGCAGTGGAGCAGATGGCGTATCATCATCACGACTGGATCATCTTCAAGAACTGGTGCCGCCCAGGAGCCGATTGCGTCACACCAGGGTTATACGCCATGGTTGGAGCCGCGGCCTGTTTGGGCGGTGTGACCCGTATGACGGTGTCTCTGGTGGTCATCATGTTCGAGCTGACGGGCGGACTCGAGTATATCGTCCCTCTGATGGCGGCGGCGGTCACCAGTAAATGGGTGGCGGACGCGTTTGGGAAGGAGGGGATCTACGAGGCGCACATCCAGCTGAACGGCTACCCGTACCTGGACCAGGACGAGTTCACACACCGCACGCTGGCCACTGACGTGATGCGCCCGCGCCGCAGCGAGCCGCCGCTGTCTGTCCTCACGCAGGACAGCAGCACGCTGGAGGAGGCCGAGGCGCTCATCACACACACCGACTACAACGGCTTCCCGGTGGTGGTGTCCCGCGAGTCTGAGCGACTCATCGGCTTCGTGCAGAGACGAGACCTGATCCTGGCTATcaagAACGCGCGTCAGAAGCAGGACGGTGTGGTCAGTAACTCAGTGGTGTATTTCACTGAAGACGCTCCTCAGCTTCCAGCATCAAACACTCAGCCCCTGAAGCTCAGACGGATCCTGAATCTGAGCCCGTTCACCGTCACCGACCACACGCCCATGGAGACCGTGGTGGACATCTTCAGGAAACTGGGCCTGCGGCAGTGTCTGGTCACACGCAGCGGACGTTTGCTGGGCATCATCACGAAGAAGGACGTGTTGCGTCACATGGCACACATGATGAACCAGGACCCAGAATCCATCATGTTCAACTAATCCCGTGCACCCTTCAGTCCTGTACACTTGCACACTAACAAGTGCTCACGTGGCCAAAACCAGACCTGTGCTCGCTTTactgttgttgctttttttatgccatatttatattttactgtaaGCCGCTGATCAACACTGTAAACATGTGCAATGAGAACACACTTTACGTACGGTACGTCActttaatatatctgtttattacgTGATGTGTCATAACGCAATGCAAGACGTAATTCAGACGACTAATCTACCGTGTGATATTGAGCATTTTACACTGGGTTTATCTGctctgttattatttattaatatttataacattatgaATGTTAGTTTTGATCTTCATGATCTTATGTATTGAATCATGAATATTGTTGTTGTAAAATAAACACCACAGCTCTGTTACGG

Function

symbol description
clcn4 Predicted to enable solute:proton antiporter activity and voltage-gated chloride channel activity. Predicted to act upstream of or within chloride transport and transmembrane transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus; early endosome; and synaptic vesicle. Predicted to be integral component of plasma membrane. Is expressed in brain; eye; gill; heart; and immune system. Human ortholog(s) of this gene implicated in Raynaud-Claes syndrome. Orthologous to human CLCN4 (chloride voltage-gated channel 4).

GO:

id name namespace
GO:0055085 transmembrane transport biological_process
GO:0006811 ion transport biological_process
GO:0006821 chloride transport biological_process
GO:0005768 endosome cellular_component
GO:0005769 early endosome cellular_component
GO:0005794 Golgi apparatus cellular_component
GO:0005886 plasma membrane cellular_component
GO:0005887 integral component of plasma membrane cellular_component
GO:0008021 synaptic vesicle cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0015299 solute molecular_function
GO:0005247 voltage-gated chloride channel activity molecular_function
GO:0031404 chloride ion binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-061013-353 Predicted to enable solute:proton antiporter activity and voltage-gated chloride channel activity. Predicted to act upstream of or within chloride transport and transmembrane transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus; early endosome; and synaptic vesicle. Predicted to be integral component of plasma membrane. Is expressed in brain; eye; gill; heart; and immune system. Human ortholog(s) of this gene implicated in Raynaud-Claes syndrome. Orthologous to human CLCN4 (chloride voltage-gated channel 4).

Ensembl:

ensembl_id ENSDARG00000035808

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00008296 True 2813 mRNA 0.54 12 44144612 44163164

Neighbor

gene id symbol gene type direction distance location
XLOC_004381 FO704721.2 coding downstream 21154 44123327 ~ 44123458 (-)
XLOC_004380 FO704721.3 coding downstream 24258 44100339 ~ 44120354 (-)
XLOC_004379 FP016005.3 coding downstream 106920 44030729 ~ 44037692 (-)
XLOC_004378 FP016005.1 coding downstream 113650 44019844 ~ 44030962 (-)
XLOC_004377 INHBB coding downstream 195727 43948091 ~ 43948885 (-)
XLOC_004383 SHROOM2 coding upstream 15396 44178560 ~ 44214767 (-)
XLOC_004384 CABZ01112732.1 coding upstream 102558 44265722 ~ 44276686 (-)
XLOC_004385 LOXL4 coding upstream 173993 44337157 ~ 44339220 (-)
XLOC_004386 LOXL4 coding upstream 177048 44340212 ~ 44347587 (-)
XLOC_004387 NA coding upstream 221650 44384814 ~ 44385749 (-)
XLOC_004063 CR854846.1 misc downstream 28016934 16127382 ~ 16127678 (-)
XLOC_004019 CR450764.8 misc downstream 31452921 12691395 ~ 12691691 (-)
XLOC_004015 CR450764.4 misc downstream 31522845 12621518 ~ 12621767 (-)
XLOC_004013 CABZ01022569.1 misc downstream 31553316 12590999 ~ 12591296 (-)
XLOC_004008 BX000700.19 misc downstream 31631350 12512966 ~ 12513262 (-)
XLOC_004376 NA non-coding downstream 428308 43713710 ~ 43716304 (-)
XLOC_004374 NA non-coding downstream 678092 43461395 ~ 43466520 (-)
XLOC_004373 NA non-coding downstream 687354 43455469 ~ 43457258 (-)
XLOC_004389 NA non-coding upstream 284531 44447695 ~ 44450349 (-)
XLOC_004390 NA non-coding upstream 288076 44451240 ~ 44451660 (-)
XLOC_004393 NA non-coding upstream 359642 44522806 ~ 44524930 (-)
XLOC_004395 NA non-coding upstream 438697 44601861 ~ 44603625 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
bowfin (Amia calva) AMCG00014186 clcn4 coding CM030128.1 CM030128.1 3617227 ~ 3629082 (+)