XLOC_004403 (eif4a3)


Basic Information

Item Value
gene id XLOC_004403
gene name eif4a3
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007122.7
NCBI id CM002895.2
chromosome length 45484837
location 44878571 ~ 44898129 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00008329
agttctAATAAACTTTCGACCACAGCTGTATCACTTTTTTATTAAGctccaaaacattcattcattcattcatttaatcattcattcattcattttcttgtcagcttagtaacttttttaatccggggtagccacagcgcaatgaaccgccaacttagccagcacatttttacgcagcggatgcccttccagccgcaacccatctctgggaaaagctCCAAAACAGTGTATacaatataaacataaacatgcaGTAACAAATaggcaaaatatttatatttaacaatcaaaaacatacaaaaacgggGAGAAACAACTAAACACAGagacagctgtatcccttttttattttttattttttcagctgTATCCTTTCTAGCGACGCCAGGACTCTTGTGTGACGTCACTGCGCGTCTCCTGCTTTGTGCGTCACCGGTGCGACACACGCGGCTCTCTACGCGCACAGTCGCGCTTTCATATTTTAACTCGTAATTTACACCGAAATCCGTCACAATTATGGCCACCGCCGTCGTTCCCGTGAGGAAGAGGATCCTGAAGGAGGAAGACATGACGAAGATTGAGTTTGAGACGAGTGAAGAAGTGGACGTGACGCCGACGTTTGACACGATGGGCCTGAGGGAGGATTTACTGCGCGGGATCTACGCATACGGTTTTGAGAAGCCATCGGCCATCCAGCAGAGAGCCATCAAACAGATCATCAAGGGCAGAGACGTCATCGCACAGTCACAGTCTGGAACTGGTAAAACAGCCACCTTCTGTGTCTCAGTGCTGCAGTGTCTGGATATACAGGTACGAGAGACTCAAGCGTTGATTTTGGCTCCAACCAGAGAGTTAGCAGGACAGATCCAGAAGGTTTTACTGGCTCTGGGCGACTACATGAACGTTCAGTGTCACGCGTGTATCGGCGGCACAAATGTCGGTGAAGACATCCGGAAGCTGGATTACGGTCAGCACGTGGTGGCAGGAACGCCTGGACGAGTGTTCGACATGATCCGCAGGAGGAGTTTAAGGACTCGCGCCATCAAGATGCTGGTGTTGGATGAAGCCGATGAGATGCTCAACAAGGGTTTTAAGGAACAGATTTACGACGTGTACCGATACCTGCCGCCGGCCACTCAGGTGTGTCTGATCAGCGCCACACTGCCACACGAGATCCTGGAGATGACCAACAAGTTCATGACCGACCCCATCCGCATCCTGGTCAAACGtgatGAGTTGACTCTGGAGGGCATTAAGCAGTTCTTCGTGGCCGTGGAGCGCGAGGAGTGGAAGTTCGACACTCTGTGTGATCTGTACGACACGCTGACCATCACACAGGCCGTCATCTTCTGCAACACCAAACGCAAGgtgGACTGGCTGACAGAGAAAATGAGGGAGGCAAATTTCACCGTATCCTCGATGCACGGAGACATGCCTCAGAAAGAGCGAGAGTCCATTATGAAGGAGTTCAGATCTGGAgccagTCGAGTGTTGATCTCCACAGACGTTTGGGCCAGAGGTCTGGATGTGCCGCAGGTTTCCCTCATCATTAACTACGATCTTCCCAACAACAGAGAGCTGTACATCCACAGGATTGGTCGATCGGGTCGTTACGGCAGGAAGGGTGTGGCCATCAACTTTGTGAAGAATGACGACATCCGTATCCTGCGTGATATCGAGCAGTACTACTCCACACAGATCGATGAAATGCCCATGAACGTGGCTGATCTGATCTGAGAACAGAGATTATCCCAGAACAGTTCTGCTTTCCTCTGCATCTTTATTTCCCATTTCCATTAGTAATTgcctttttattttctatttttatgtaGTTTGAGCGCTCTGATGTTACAGGATCTGGTGTTCAGATCAGAGCTTCCATTGGGTTTTGTAAATAAAGAATCTTTGTCTCCATCTTTGAGCTCATCTCTGTTTTATTCGAGTTCTTTATTGTTTACCGTACATCAGGTCTTGAGATTATAGATtagttgcattttaaaataaatgttaaattaaatgtaaattaagctTAGTAAtatccttatttttatttatttatttatttatatctctatttttattttaacctgttgccaaaataatttttttatattgtttttatttagtttgacttGGTGCATTAAAATATcttacaatattaaaatattacaggaTGGGTTAAAGATAAGCATAATTAAATTTAATCTCTAAATTTatcatattaaatacaatttcatATTTTTTGAGTCGGTAATGCAGGCAGTATAGGGAATATTCACTATGCCACTCGTTTTTAATGCCTTGTTACTCTTCACCCAGTCTCTATACACTCCACAGGCACATTTAACCACTGAAGAATaatacaaaaatgacaaaaacaagacCACTAGAGCAATCAAATCCTAACTATTGTAACCCTTCAGTGTGAATTCAGGAAATTCTAACTATTTCCTCGTTATTATCATGCCTATTTTTaacattggctgtttattagtctTCATAAATTAGATATATTCTGCATGAGGATATCCTACATCCATAATCCTACAAATACCTCATTTAACTACTACTACCCtgttaactattaataagcagcaagtTAATTGAGGCAAATCATGCTTGAACCATAAAtaaatttattgttaattattacaaCAATGTACAATGATACTGAAATGGTGCAGGATATTTATGTTGCTCAATCTGTGTGATGAGGCTGTGCCTTTTAGAAAGATTCATATAGATTCATATATCAAGATTAAAAGAGAATGATAAAGCTGTTGAGTTATTTTCCACTTTAGGATGTGTATAGTCTTCTGGAGAGTCATCGCTCTGGAGTTTGCAGGtatattattgctattatattattttcttcaatattgttttacattaaaatggtttattttgtCGGTAACAcgttacaataaggttgtattagttaatataaatgcatttactaacatgaacaaacaattaacaatatTACAGTGTTGATGCTTGTTAACGttactaaatgaaaataaaatcatttattattagtttatcatAACTGATGGTGCATTAATTAGTCAACAAGCATGAACTCTGATGCTcacaataatgcattagtaaatgttcaactgTGATTAATGCTGTTCATGTGTCGTtcatagttcatgttagtaaattcattaactaatacaaccttattgtaaagtgtgactgtgtgtgtgtgtgtgtgtttgttaatgtACTGATGAATGAATGCGTCTCTGTGTAAGAGTGAAGCTCcagctgattctctctcacacacgtgACTGTGGATGAGCTGCTGTAACCATGGAGACAGACCATAATCACTGACACCATTCACTCACGCCGTCTGCTATAGAGCTCATTTGACCTGCTTTTTCATGCTGTTTACTAATCTTTATCAACTTaatgatttacacacacacacacacacacacacacacactgtaaaagcgtttaacagtttccatattctGTGATTTGCAGGTGTTTTCAGATTATTTGCGGGTATAAATTGCAGTG
>TCONS_00008499
CAAGTTCATGACCGACCCCATCCGCATCCTGGTCAAACGtgatGAGTTGACTCTGGAGGGCATTAAGCAGTTCTTCGTGGCCGTGGAGCGCGAGGAGTGGAAGTTCGACACTCTGTGTGATCTGTACGACACGCTGACCATCACACAGGCCGTCATCTTCTGCAACACCAAACGCAAGgtgGACTGGCTGACAGAGAAAATGAGGGAGGCAAATTTCACCGTATCCTCGATGCACGGAGACATGCCTCAGAAAGAGCGAGAGTCCATTATGAAGGAGTTCAGATCTGGAgccagTCGAGTGTTGATCTCCACAGACGTTTGGGCCAGAGGTCTGGATGTGCCGCAGGTTTCCCTCATCATTAACTACGATCTTCCCAACAACAGAGAGCTGTACATCCACAGGATTGGTCGATCGGGTCGTTACGGCAGGAAGGGTGTGGCCATCAACTTTGTGAAGAATGACGACATCCGTATCCTGCGTGATATCGAGCAGTACTACTCCACACAGATCGATGAAATGCCCATGAACGGTCAGTACCAACTTTCATCCTTATTCTGATCTATTAGTTATTAATTTTAGAGCAAGACGGAATAGGAATTAAGCTAAAACAAATGCCCAAAAGACAATCAAATTAAGCCCAAACACGAGCAAATGCATTCaaatctacatttatttattgctcattcacacatattttaatttcaatgtaAACTGCAGATTTAATTTGTGCTGTTAAggttaatcatgattaattgcatacaaaataaaagtttgtttacaCAATATGTTGTGCTGTGTACAGTTTTTGTGTTCGT
>TCONS_00008500
atattcttttgttcaTGTTGTAAATGTATTTCATGCTTTTAATTAACAATAACTGTGCACCCTTTATACTGTTAGGTACGAGAGACTCAAGCGTTGATTTTGGCTCCAACCAGAGAGTTAGCAGGACAGATCCAGAAGGTTTTACTGGCTCTGGGCGACTACATGAACGTTCAGTGTCACGCGTGTATCGGCGGCACAAATGTCGGTGAAGACATCCGGAAGCTGGATTACGGTCAGCACGTGGTGGCAGGAACGCCTGGACGAGTGTTCGACATGATCCGCAGGAGGAGTTTAAGGACTCGCGCCATCAAGATGCTGGTGTTGGATGAAGCCGATGAGATGCTCAACAAGGGTTTTAAGGAACAGATTTACGACGTGTACCGATACCTGCCGCCGGCCACTCAGGTGTGTCTGATCAGCGCCACACTGCCACACGAGAT

Function

symbol description
eif4a3 Predicted to enable RNA helicase activity and mRNA binding activity. Predicted to be involved in regulation of alternative mRNA splicing, via spliceosome. Predicted to act upstream of or within RNA metabolic process; mRNA transport; and regulation of translation. Predicted to be located in nucleus. Predicted to be part of U2-type catalytic step 1 spliceosome and catalytic step 2 spliceosome. Predicted to be active in nucleolus. Human ortholog(s) of this gene implicated in intellectual disability. Orthologous to human EIF4A3 (eukaryotic translation initiation factor 4A3).

GO:

id name namespace
GO:0000381 regulation of alternative mRNA splicing, via spliceosome biological_process
GO:0006397 mRNA processing biological_process
GO:0006417 regulation of translation biological_process
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay biological_process
GO:0051028 mRNA transport biological_process
GO:0008380 RNA splicing biological_process
GO:0071013 catalytic step 2 spliceosome cellular_component
GO:0005634 nucleus cellular_component
GO:0016607 nuclear speck cellular_component
GO:0005681 spliceosomal complex cellular_component
GO:0005730 nucleolus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0071006 U2-type catalytic step 1 spliceosome cellular_component
GO:0005524 ATP binding molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0003676 nucleic acid binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0003723 RNA binding molecular_function
GO:0003724 RNA helicase activity molecular_function
GO:0003729 mRNA binding molecular_function
GO:0004386 helicase activity molecular_function

KEGG:

id description
ko03040 Spliceosome
ko03013 Nucleocytoplasmic transport
ko03015 mRNA surveillance pathway
ko03019 Messenger RNA biogenesis
ko03041 Spliceosome
ko03009 Ribosome biogenesis
ko03012 Translation factors

ZFIN:

id description
ZDB-GENE-040426-915 Predicted to enable RNA helicase activity and mRNA binding activity. Predicted to be involved in regulation of alternative mRNA splicing, via spliceosome. Predicted to act upstream of or within RNA metabolic process; mRNA transport; and regulation of translation. Predicted to be located in nucleus. Predicted to be part of U2-type catalytic step 1 spliceosome and catalytic step 2 spliceosome. Predicted to be active in nucleolus. Human ortholog(s) of this gene implicated in intellectual disability. Orthologous to human EIF4A3 (eukaryotic translation initiation factor 4A3).

Ensembl:

ensembl_id ENSDARG00000102978

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00008329 False 3534 mRNA 0.40 12 44878571 44898129
TCONS_00008499 False 816 lncRNA 0.44 5 44880825 44889032
TCONS_00008500 True 440 lncRNA 0.49 4 44889048 44893409

Neighbor

gene id symbol gene type direction distance location
XLOC_004402 opn6a coding downstream 2566 44858979 ~ 44876005 (-)
XLOC_004401 NA coding downstream 19970 44852582 ~ 44858601 (-)
XLOC_004400 map1lc3c coding downstream 76603 44798056 ~ 44801968 (-)
XLOC_004399 BX569779.1 coding downstream 122088 44750935 ~ 44756483 (-)
XLOC_004398 NA coding downstream 156240 44716828 ~ 44722331 (-)
XLOC_004404 zgc:171772 coding upstream 585 44898714 ~ 44906703 (-)
XLOC_004405 pfklb coding upstream 12486 44910615 ~ 44931962 (-)
XLOC_004406 orc2 coding upstream 39076 44937205 ~ 44945636 (-)
XLOC_004407 ldb1b coding upstream 55469 44953598 ~ 44999858 (-)
XLOC_004408 cant1b coding upstream 224018 45122147 ~ 45153006 (-)
XLOC_004063 CR854846.1 misc downstream 28750893 16127382 ~ 16127678 (-)
XLOC_004019 CR450764.8 misc downstream 32186880 12691395 ~ 12691691 (-)
XLOC_004015 CR450764.4 misc downstream 32256804 12621518 ~ 12621767 (-)
XLOC_004013 CABZ01022569.1 misc downstream 32287275 12590999 ~ 12591296 (-)
XLOC_004008 BX000700.19 misc downstream 32365309 12512966 ~ 12513262 (-)
XLOC_004395 NA non-coding downstream 274946 44601861 ~ 44603625 (-)
XLOC_004393 NA non-coding downstream 353641 44522806 ~ 44524930 (-)

Expression


Co-expression Network