XLOC_004621 (acta2)


Basic Information

Item Value
gene id XLOC_004621
gene name acta2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007123.7
NCBI id CM002896.2
chromosome length 49182954
location 17100021 ~ 17116481 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00009156
aaattttctgttcCAAACGTATgcataagattttattttatttactttttgctttgtttttacagTACAGCTTGGGAGTTTAAACTTTTAAACTCGTGTGACCTATGTACTTAAGTGACCAAATGTCTTTGCCATTCCTTCTCAGGTGTGGGCCGTGGTGAGCGTCTGTGTAGCAGATCAGGCCCAGCCCTGTGTTTATTCTCGTGCATAGTGAAGTCCCCACAATTTCTGAGGAGAAAAAAGGAAAAGGTCCATTGGAATGCCCAGAGTAAGGAGGCAAGAGGCCGCCCTGGTGCTGCCCGGATTGGAGTGTTTTCTCCCAGTCATCCCTATAAGGCTTTAGTGGAGTGAGGCTACCGATCCGAGTGCAGCCCAGGCTCCTTGTTTGGGATGTTAGAGGGTGTGGTGAGCAGAGATGGAAACTACATAAGTACACCACAAACCAGTGAGGTGTACACCATCACCAAGTGGCTAAATACCCCCCCGGCCCAGCACTGTCAGGtgattGTCTCCTGTTGGAGTAAGAAAGGATATCCGAGCTGAAAATGTGTGACGACGAAGAAAGCACTGCCCTGGTGTGTGACAATGGATCTGGACTGTGTAAGGCAGGCTTCGCCGGGGATGATGCTCCCAGAGCGGTGTTCCCTTCCATAGTGGGACGTCCCAGACATCAGGGAGTGATGGTAGGAATGGGGCAGAAAGATAGTTACGTTGGTGATGAGGCGCAAAGCAAGAGGGGAATCCTGACTCTCAAGTACCCCATCGAGCACGGAATCATCACAAACTGGGACGATATGGAAAAAATCTGGCATCACTCTTTCTACAACGAGCTCCGTGTGGCTCCAGAGGAACACCCCACTCTGTTGACAGAAGCCCCACTTAATCCTAAAGCCAACAGGGAGAAGATGACCCAGATCATGTTTGAGACCTTCAATGTTCCAGCCATGTATGTAGCTATTCAAGCAGTGCTGTCTCTCTATGCTTCTGGACGCACAACAGGCATTGTGCTGGACTCTGGTGATGGTGTCACCCATAACGTACCCATTTATGAGGGCTACGCTCTTCCACATGCCATTATGCGTTTGGACTTGGCCGGCCGTGATCTCACTGACTACCTCATGAAGATCCTAACTGAACGAGGCTACTCATTCGTCACCACTGCTGAAAGAGAAATCGTCCGTGACATCAAGGAGAAGTTGTGCTACGTGGCTCTGGACTTTGAGAATGAGATGGCCACCGCTGCCTCTTCCTCCTCTCTGGAGAAGAGCTATGAGCTTCCCGATGGACAGGTCATCACCATTGGCAATGAGAGGTTCCGCTGTCCTGAGACGCTGTTCCAGCCGTCCTTCATCGGGATGGAATCTGCTGGTATTCATGAAACCACCTACAACAGCATCATGAAATGCGACATTGACATCCGTAAGGATCTGTACGCCAACAATGTGCTGTCTGGCGGTACCACCATGTACCCGGGCATTGCAGACAGGATGCAGAAGGAGATCACTGCTTTGGCTCCCAGCACCATGAAGATCAAGATAATCGCTCCACCTGAGCGCAAGTACTCAGTATGGATCGGCGGCTCCATCCTGGCCTCTCTCTCCACCTTCCAGCAGATGTGGATCAGCAAGCAGGAGTATGATGAAGCCGGACCCTCTATTGTGCATCGCAAGTGCTTCTAGACGACACCTCCAGCCCCCTCCTGGTCCCGTAATTCTGCTATTGCTTCATAGCCTGTAAACTGTGAACCTGCCCTTTATTTCCCTCTATTGTATTGTCTTTGCACTGCCCACTTCTGTTTGAATGTTCTGATCTAATTATGTCATGACCATATAGAGGTGTTTTCGGTTGGGTTATTAAGCTTGAACGTGCTGCCAATAAAGAAGATTGGGGGGATTTTTTTTAGGGTGGTGAGACTCCAGAGATGAGGAGAGCGTGTTATTCTTCCTATTGTGTTTAAATGCTACGAGGAAACACAACTGCATGTCGGCTTTCAGGCAGTCTGTTTGGATTTCATATGAAGGAATAAAGCTCAGCAATAATTAATTTGTCTTTTCATTGCTCACTACTGAgaaaaactaagaaaaacaacacggtacaaaaaaaaaatccaaaacacaAGTGAAAAAAATGAGGCGGTGATTAACATTGTTGCTTAACAGCAGGAAGGTTTCTAGTTCGAGTCCCAgatgggccagttggtatttctgcatggagtttgcaggTTTCCTCCGGCTTCGctcacagtccacagacatgcgctataggtgaatttaataaactattggccatagtgtatgggtaTGAGCTTGAATGagagaatgtatggatgtttccatgtactgggttgcagctgaaagcgTATCTGCTTCATAAAACATGGTTAAATAGTTGACGGTccattacgctgtggcaacctctgataaatcagagactaagctgaaggaaaatgaaagttGTGAAAGATTAACCTTCACATTCCTAAAGTATATTGTACAACAGCTTCAAAATTCCAAGGCATGAAGGCATCAAGGCATGTCCAAATCCAAATTCTGCTTCACTTCTTGTCTATTGTGCATTCCATTTCTGATCATTTAGCTAGACAAGTTAGTATTGTAGTACTAAGGAAATATTTCGTTTTTTATAGCCAAAAACTCTCATATTTGTTGTGTGATTAAATTGTAATGCAGTCTGTTGATTTTTGCTAAAGTGTACAAACTCTGCCTCTGAGTCACTTGCTAATAGGGCAGCTGTCTGGGCTTGCAGATACacccaatgtttttttattataacagca
>TCONS_00009157
GGAGTGATGGTAGGAATGGGGCAGAAAGATAGTTACGTTGGTGATGAGGCGCAAAGCAAGAGGGGAATCCTGACTCTCAAGTACCCCATCGAGCACGGAATCATCACAAACTGGGACGATATGGAAAAAATCTGGCATCACTCTTTCTACAACGAGCTCCGTGTGGCTCCAGAGGAACACCCCACTCTGTTGACAGAAGCCCCACTTAATCCTAAAGCCAACAGGGAGAAGATGACCCAGATCATGTTTGAGACCTTCAATGTTCCAGCCATGTATGTAGCTATTCAAGCAGTGCTGTCTCTCTATGCTTCTGGACGCACAACAGGCATTGTGCTGGACTCTGGTGATGGTGTCACCCATAACGTACCCATTTATGAGGGCTACGCTCTTCCACATGCCATTATGCGTTTGGACTTGGCCGGCCGTGATCTCACTGACTACCTCATGAAGATCCTAACTGAACGAGGCTACTCATTCGTCACCACTGCTGAAAGAGAAATCGTCCGTGACATCAAGGAGAAGTTGTGCTACGTGGCTCTGGACTTTGAGAATGAGATGGCCACCGCTGCCTCTTCCTCCTCTCTGGAGAAGAGCTATGAGCTTCCCGATGGACAGGTCATCACCATTGGCAATGAGAGGTTCCGCTGTCCTGAGACGCTGTTCCAGCCGTCCTTCATCGGGATGGAATCTGCTGGTATTCATGAAACCACCTACAACAGCATCATGAAATGCGACATTGACATCCGTAAGGATCTGTACGCCAACAATGTGCTGTCTGGCGGTACCACCATGTACCCGGGCATTGCAGACAGGATGCAGAAGGAGATCACTGCTTTGGCTCCCAGCACCATGAAGATCAAGATAATCGCTCCACCTGAGCGCAAGTACTCAGTATGGATCGGCGGCTCCATCCTGGCCTCTCTCTCCACCTTCCAGCAGATGTGGATCAGCAAGCAGGAGTATGATGAAGCCGGACCCTCTATTGTGCATCGCAAGTGCTTCTAGACGACACCTCCAGCCCCCTCCTGGTCCCGTAATTCTGCTATTGCTTCATAGCCTGTAAACTGTGAACCTGCCCTTTATTTCCCTCTATTGTATTGTCTTTGCACTGCCCACTTCTGTTTGAATGTTCTGATCTAATTATGTCATGACCATATAGAGGTGTTTTCGGTTGGGTTATTAAGCTTGAACGTGCTGCCAATAAAGAAGATTGGGGGGATTTTTTTTAGGGTGGTGAGACTCCAGAGATGAGGAGAGCGTGTTATTCTTCCTATTGTGTTTAAATGCTACGAGGAAACACAACTGCATGTCGGCTTTCAGGCAGTCTGTTTGGATTTCATATGAAGGAATAAAGCTCAGCAATAATTAA

Function

symbol description
acta2 Acts upstream of or within heart contraction. Predicted to be located in several cellular components, including cell body; filopodium; and lamellipodium. Predicted to be part of dynactin complex. Is expressed in several structures, including cardiovascular system; gut; mesoderm; musculature system; and swim bladder. Human ortholog(s) of this gene implicated in Moyamoya disease; megacystis-microcolon-intestinal hypoperistalsis syndrome; and thoracic aortic aneurysm. Orthologous to several human genes including ACTA2 (actin alpha 2, smooth muscle).

GO:

id name namespace
GO:0010628 positive regulation of gene expression biological_process
GO:0090131 mesenchyme migration biological_process
GO:0008015 blood circulation biological_process
GO:0060047 heart contraction biological_process
GO:0030175 filopodium cellular_component
GO:0005856 cytoskeleton cellular_component
GO:0005869 dynactin complex cellular_component
GO:0015629 actin cytoskeleton cellular_component
GO:0044297 cell body cellular_component
GO:0030027 lamellipodium cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005524 ATP binding molecular_function
GO:0000166 nucleotide binding molecular_function

KEGG:

id description
ko04371 Apelin signaling pathway
ko04926 Relaxin signaling pathway
ko04270 Vascular smooth muscle contraction
ko04812 Cytoskeleton proteins
ko04147 Exosome

ZFIN:

id description
ZDB-GENE-030131-1229 Acts upstream of or within heart contraction. Predicted to be located in several cellular components, including cell body; filopodium; and lamellipodium. Predicted to be part of dynactin complex. Is expressed in several structures, including cardiovascular system; gut; mesoderm; musculature system; and swim bladder. Human ortholog(s) of this gene implicated in Moyamoya disease; megacystis-microcolon-intestinal hypoperistalsis syndrome; and thoracic aortic aneurysm. Orthologous to several human genes including ACTA2 (actin alpha 2, smooth muscle).

Ensembl:

ensembl_id ENSDARG00000045180

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00009156 False 2794 mRNA 0.46 9 17100021 17116481
TCONS_00009157 True 1369 mRNA 0.49 7 17106117 17115730

Neighbor

gene id symbol gene type direction distance location
XLOC_004620 ch25h coding upstream 56147 17042754 ~ 17043874 (+)
XLOC_004619 slc16a12b coding upstream 113053 16967715 ~ 16986968 (+)
XLOC_004617 pank1b coding upstream 135181 16953415 ~ 16964840 (+)
XLOC_004618 dre-mir-107a coding upstream 139240 16960693 ~ 16960781 (+)
XLOC_004616 zgc:174153 coding upstream 148170 16949391 ~ 16951851 (+)
XLOC_004622 ankrd22 coding downstream 38174 17154655 ~ 17158635 (+)
XLOC_004623 rnls coding downstream 85041 17201522 ~ 17323341 (+)
XLOC_004624 AL731788.1 coding downstream 229069 17345550 ~ 17345667 (+)
XLOC_004625 NA coding downstream 307950 17424431 ~ 17427380 (+)
XLOC_004626 atad1b coding downstream 320423 17436904 ~ 17456083 (+)
XLOC_004615 NA non-coding upstream 225318 16742395 ~ 16874703 (+)
XLOC_004614 NA non-coding upstream 514967 16583373 ~ 16585054 (+)
XLOC_004613 NA non-coding upstream 529977 16567854 ~ 16570044 (+)
XLOC_004612 NA non-coding upstream 608215 16490198 ~ 16491806 (+)
XLOC_004634 BX005075.1 non-coding downstream 1009177 18125658 ~ 18125774 (+)
XLOC_004635 NA non-coding downstream 1093390 18209871 ~ 18228004 (+)
XLOC_004644 AL772266.2 non-coding downstream 1482369 18598850 ~ 18598964 (+)

Expression


Co-expression Network