gba (gba)


Basic Information

Item Value
gene id gba
gene name gba
gene type coding
species eurasian perch (Perca fluviatilis)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_053118.1
NCBI id CM020915.1
chromosome length 43092710
location 22339629 ~ 22345550 (+)
genome version GENO_Pfluv_1.0_2020_eurasian_perch_Genome

Sequence

>XM_039805192.1
TTTTCAAAATCACATGACAAAAAATCGGATCGCCGAAACAAACAAGGTGGCCCGAGGAGGAGACGCTGGTATGGCAGATTGGACAAAGTTAAGCTGACGGTGGAGTGtgaatatttttaaatgaaccCGCGGGACATGCCAGAGTTTGTATCAGGATCCTCTGAGATAAAATGGCGTTGTCATTGCCGTCATCTGTTCTTCTGGCCCTTGTTTTCCTCACAGCTGAATTGACCCTCTCTACAGGAAACAATACATGTGTTGCCAGAAACTTTGGCCATGACTCAGTGGTGTGTGAGTGTAATTCAACCTACTGTGACAGTGTTGGATCAGTCACCTTGCCCCCACTGGGCCACTACTCCTCCTACCTGACCAGCATGGTCGGCGACAGACTGGAGGCGGGCCGGGGTCAGGTCCAGGTGAACAGCACCGGCGCAGGGCTCAGGTTGACTATCGTTCCCTACCAGAAGTACCAAAAGATCAAGGGATTCGGTGGAGCTATGACGGACGCAGCAGCTGTTAACATCCTGTCTCTTTCTGCTGGTGCACAGGACCAGCTGCTGCGACAGTACTTTTCCCCTGAAGGTATTGGCTACAGCGTGGTGCGTGTCCCCATGGCCAGCTGTGACTTCTCCACCCGTCTGTACACGTATGCTGACACACCTGGAGACTACAACCTGGACAATTTCACACTGGCCCCCGAGGACATCAAAATGAAGATCCCTCTCCTGCAGCGTGCTCAGGCCTTATCTCCTCGCCCCCTGTCTCTGCTGGCCAGCGCCTGGAGTGCCCCCGCCTGGATGAAAACTAACGGTGCTCTCATAGGAAAGGGCTCCCTGAAGGGCCAGCCTGGGGGCAAGGAGCACAAAACCTGGGCTCAGTACTATATCAGgTTCCTTGAGGAATATGCTAAATATAACTTGACCTTCTGGGCTTTGACCACAGGGAATGAGCCCTCTGCAGGACAGATAACAAACTACAGTTTCCAGGCACTTGGCTTCACTCCTGAGGAGCAGAGGGACTGGGTGGCTCTGGACCTGGGCCCTGCCCTGCACGCTTCTtcacacccacgcacacacgTCCTCCTACTGGATGACAGCCGCCTGCTGCTGCCTCACTGGGCTAAAGTGGTCCTAAATGACATTCATGCAGGAAGGTACATTCATGGCGTTGCAGTTCACTGGTACATGGACAGCCTTGTCCCAGCAGAGATAAGCCTGGGAGTCACCCATCATCTGTACCCAGAGTATTACCTGTTTGGCACAGAGGCCTGCTCTGGCTGGAGCCCGCTAGACAGAGGGGTGAAGCTGGGTAGCTGGGACAGGGCTGAACAGTACGCACATGATATTATAGAGGACTTAAATCATTATGTGGTGGGGTGGACTGACTGGAATTTGGCGTTGGACCAGACTGGTGGGCCAAACTGGGTTAAAAACTTTGTGGACAGCCCTGTTATAGTGGATGCGCAGCGTGATGTCTTCTACAAGCAGCCAAACTTCTACAGCATGGCCCACTTCAGCAAGTTCCTGTGGGAAGGGTCTCAGAGAGTGGGTGTAACCGCCAGTCGGGAAACAGAACTGGAATACTCTGCCTTCATCAGACCAGATGGCTCAGTAGTGCTCATCATACTCAACAGGTCATCATCAATGATCCAGTTTGAGGTATGGCATCCCGCTGTGGGCTACATCTCCTCCACTGCACCGGCTCATTCATTGCTCACACTTGCTTGGAACACACACTGATCATTAATACAAGTTCATATTTGTTCCACCATCATTAATTTTTCTATGCATATTCCAAAATGCCACAAAAAGTAACTGTTTCCTGTTGGAACCTTCTCATTACCAAAGTGGTTACTTTGAGTGCTTTGTCGGTATTGAACCACTCAGACGCACATTTTCTAATTACCGGTGCaagattaatttatttttaaattccgTGCTTTTATGCACAGCTTTACTGATTTAAGTGgtcactttattttatttttggtcACTTTATGTATTTTGTTAACCTTGGCAAACTAAAATAAGAACCTTAcctcatttgattttcattcaAAAGCCTAAAATGCTTTTTTATGCACTGATTCCTATCAGGAATGGTACCTGAAAGTAATGAATGTATCAGTTCACCAGAATGACCTTTACTGAAGCGTAACTGGTGCCTTGATTTCCCGCTAATGATGAAGTATCGTCACACCATCTTATCAAGAAATCATATAAATAATGTACAGAAATTAAAATGCCTTCTGCTGTTgctatttaattttaaataaagtgcATTTTGGTTCAAAATA

Function

symbol description
gba Enables glucosylceramidase activity. Acts upstream of or within neuron cellular homeostasis; regulation of ossification; and swimming. Predicted to be located in lysosomal membrane. Is expressed in brain; fin; and liver. Used to study Gaucher's disease. Human ortholog(s) of this gene implicated in Gaucher's disease (multiple); Lewy body dementia; Parkinson's disease (multiple); and Parkinsonism. Orthologous to human GBA (glucosylceramidase beta).

NR:

description
glucosylceramidase isoform X1

GO:

id name namespace
GO:0006665 sphingolipid metabolic process biological_process
GO:0005975 carbohydrate metabolic process biological_process
GO:0004348 glucosylceramidase activity molecular_function

KEGG:

id description
K01201 GBA, srfJ; glucosylceramidase

RNA

RNA id representative length rna type GC content exon number start site end site
XM_039805192.1 True 2296 mRNA 0.48 12 22339629 22345550

Neighbor

gene id symbol gene type direction distance location
dap3 dap3 coding upstream 696 22332416 ~ 22338933 (+)
fdps fdps coding upstream 43724 22289236 ~ 22295905 (+)
rab13 rab13 coding upstream 60730 22273092 ~ 22278899 (+)
adar adar coding upstream 156201 22167465 ~ 22183428 (+)
s100w LOC104962188,LOC103388219,LOC106537129,LOC102230839 coding upstream 215192 22121704 ~ 22124437 (+)
polr3c polr3c coding downstream 12241 22357791 ~ 22366153 (+)
LOC120562192 LOC104934671 coding downstream 102969 22448519 ~ 22455722 (+)
prpf3 prpf3 coding downstream 115581 22461131 ~ 22469782 (+)
tars2 NA coding downstream 145203 22490753 ~ 22506497 (+)
adamtsl4 LOC104944899,LOC101074756,LOC106573456 coding downstream 173568 22519118 ~ 22556292 (+)
G74769 NA non-coding upstream 84151 22255271 ~ 22255478 (+)
G74765 NA non-coding upstream 93866 22245489 ~ 22245763 (+)
G74764 NA non-coding upstream 96596 22242817 ~ 22243033 (+)
G74760 NA non-coding upstream 155592 22183783 ~ 22184037 (+)
G74737 NA non-coding upstream 209715 22129652 ~ 22129914 (+)
G75042 NA non-coding downstream 573202 22918752 ~ 22920103 (+)
G75045 NA non-coding downstream 579042 22924592 ~ 22925155 (+)
G75065 NA non-coding downstream 637342 22982892 ~ 22987322 (+)
G75069 NA non-coding downstream 648870 22994420 ~ 22994706 (+)
G75077 LOC104960445 non-coding downstream 671257 23016807 ~ 23018595 (+)
rusc1 LOC104958857 other upstream 27109 22264939 ~ 22312520 (+)
fam189b fam189b,LOC102796117 other upstream 51335 22279556 ~ 22288294 (+)
kcnn3 kcnn3,LOC104958859,LOC106930148,LOC106962094 other upstream 91102 22197712 ~ 22248527 (+)
snx27b snx27,LOC102196713,LOC102288812 other upstream 184945 22139780 ~ 22154684 (+)
LOC120561537 NA other upstream 200406 22137547 ~ 22139223 (+)
rprd2b NA other downstream 124428 22469978 ~ 22489944 (+)
celf3b LOC104944900,LOC100708447,LOC107088821,LOC107379582 other downstream 214394 22559944 ~ 22585572 (+)
arnt NA other downstream 264468 22610018 ~ 22625953 (+)
LOC120562537 NA other downstream 314929 22660479 ~ 22667885 (+)
LOC120562539 LOC102295960,LOC100711672,LOC102209551,LOC101487210,LOC102786116 other downstream 343520 22689070 ~ 22705416 (+)

Expression


Co-expression Network