cdkn1bb (cdkn1b)


Basic Information

Item Value
gene id cdkn1bb
gene name cdkn1b
gene type coding
species eurasian perch (Perca fluviatilis)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_053119.1
NCBI id CM020916.1
chromosome length 42187026
location 23144257 ~ 23148303 (-)
genome version GENO_Pfluv_1.0_2020_eurasian_perch_Genome

Sequence

>XM_039809715.1
CTCCGAGTCAAACTCCACTCTCAATCCCAAGTACATCTCTAAATCGCCATATTGGGTACTGAGAAGGTTTGTCTGCAGTTCCTCTCACTACGGGACGAATTTGACAGAGCGGCTTCAGTTCCTGGCCACTTTGTTTTGATGATCCGCGGAGACAACTTTCGGCGCGGCCGTTACCGTTTCCAGCCCGACGTATGCATGGCATAAGTCGTTTTACGCTTGTTTTGGATCTTGCTCAGCGACGAGGAGATACCCGTTGTTTTTGAGCGGTgggttttttcttttgaaaactGGACGCTGCAGGCTGTTTGAAAAATTTCGTCTTAATTTAGGGGGAAATGTCAGATGTTCGACTATCAAACGGGAGCCCGACTTTGGAGCGGACGGACTCCCGGGTGTCGGATCACCCAAAACCGTCAGCTTGCAGAAGCCTCTTCGGCTCGGTGGATCACGAAGAGTTAAAGAGGGAGTTAAAGGGACATTTGCGGGAGATGGAGGAGGCTGCCTCCGCCAAGTGGGGCTTCGACTTCGCCAATCACACGCCGCTGGCCAACGGCAGGCTCAAGTGGGAATTAGTGGATTGTAGAGACGTCCCGGATTTCTACAACAAGCAACCGCGGAGGGAGAAGAGAGTCTGCTCTGCTGGGAATAACAATGTGGATCTAAATGGGAATCATAACTGTGTTGTGGTGGCTCCGAGCGAAGACACCGACAGGTCTGACGCGCAGATGGAGTGCACGGAACAGTGCACCGGGCTGAGGAAAAGACCTGCATGTCACGACCCCTCGGCCCAAAATAAGAGGTCACACACCAGCTCAGATGAGGTTACTTGTCCAAGCCTGGGCCACTCTACAGAACACACACCCAGAAAGACCAGTCCCAAGAGGCAAACGTGAGGGCCAGGAACGAGCCAAAGATGTATTTCCCCTGTTACGTGGGAAACCTCAGTGTTGGCCGATTTTGGAAGAGGAACTACACAGCATCAGAAACATATCAACTCTCCTGAAGATGGGGGAGGACGCTGTTGAAGCACTGAATAGAAACACTAAAGTTGTGGCACTCAATTAAAAAGTTACTGCCTCTAAAAGCAGTCAATGTAGCAGTATGCAATTAGGTTGGATTTCCTTTTTTGCTCATTTTTTTACTACCTGtgtgtaaataaatatacatattatattatatttctcTCCATATGTAGCACATAAGAAAATATGATTTGAACACAAATCCTTTATGTAAAAAGGTGTGAATTTTTGATTTGACTTGAAGAATTGCAGTGTAGTTTGATACATGTTTCCAAAATgctgttctgtttttttgtcattttattttctgaaagGCGGTGTGACTTTGACACGGTCACTAATtgctacatttaaaaacaaaatcatggCTTCTTACAGTTTCTTAACAGTGTATCTTCACTCCGTCATCTTCCTAACTCAGCAGTGAAGAATGGTACAAATGTAGCTCatctgttttttgtattttattttatttttttcctttggtCACTTCATTTTCACCAAGTGCAGGTTCTCCTATTAGATCTATTTCCCCAGGAAATCAACACagacaaaaataattaatatttcTGTTAGGACTTCCTTTACATCAtctgatatttattttttgaaaggtGCTTTTAGCATCAGCTGAATCCTggaatatgatttttttaagtTCTCCTGCACACCTCAGCCACATGTAATGGTGTGTTTGATTTGGAGTTGTGAGGTACTCTGATATTGAAGGACAAAGACCATACAAACTGCACAGCTTGTGTTGTAAAGTCATCCTCTCCTTGACTTGATTCCTTTTTGTTTCATCAGCCTTAATGCTCTTCACAGAGGAGGTATTCTGAAAAGGGTTGAATGTCCTACAATACCAAAAACATGGTTGCTTCAGTATGGTTGCCAGCACTGCCTGTGCGCCTTAATTgacttcacatttttttttgtgataacCTAGATATAAATTTCCATTTGTTTGTACTTGTTTCACCAATGTTGTTAGCCTGCTGAGGATGCAAATGTGCACATCACAAGCATCTAAAAGCTTCCCTTTATTTGCCTAAAGTGTAGGTTATATTCAAAGAGACCAGTGTACAcctggatggagagagagagaacagaatcGCAGTCACCATgcctgtgtatttgtgtaaatCTTTGCAATGTACCTATGTACATAATTTTGTAAAAACACTGAGAAATTATACTAACTTATTTAtgtcaagcttttttttttttatgtagaatAAAAAATGGGGTTTTGATTACGGTTATCCAAAGTGGCATTTACTTTATTataattgttgtattttgttaaagcatatttttggtagtttttttttgttttttttcttatcaaTAAGGTTGCAAACTGAGCCTGATTAAAATATTTGATGTGCATTTTGTAATGTGTGGTTATAAAATGTGTTGAAATCAATTAAAAGAGAAAATTATATCTA

Function

symbol description
cdkn1b Enables cyclin binding activity; cyclin-dependent protein serine/threonine kinase inhibitor activity; and enzyme binding activity. Involved in several processes, including G1/S transition of mitotic cell cycle; negative regulation of cell cycle; and negative regulation of vascular associated smooth muscle cell proliferation. Acts upstream of or within cellular response to lithium ion and positive regulation of protein catabolic process. Located in cytoplasm and nucleoplasm. Part of Cul4A-RING E3 ubiquitin ligase complex. Implicated in acute myeloid leukemia; breast cancer; multiple endocrine neoplasia type 4; and myelodysplastic syndrome. Biomarker of several diseases, including cervix uteri carcinoma in situ; chronic myeloid leukemia; lung carcinoma (multiple); prostate carcinoma in situ; and urinary system cancer (multiple).

NR:

description
cyclin-dependent kinase inhibitor 1B-like

GO:

id name namespace
GO:0071901 negative regulation of protein serine/threonine kinase activity biological_process
GO:0007050 cell cycle arrest biological_process
GO:0005634 nucleus cellular_component
GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity molecular_function

KEGG:

id description
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B

RNA

RNA id representative length rna type GC content exon number start site end site
XM_039809715.1 True 2470 mRNA 0.41 3 23144257 23148303

Neighbor

gene id symbol gene type direction distance location
mrps35 mrps35,LOC102787710 coding downstream 200781 22934142 ~ 22943476 (-)
adck2 adck2 coding downstream 300494 22837978 ~ 22843763 (-)
pus7 pus7 coding downstream 386267 22746489 ~ 22757990 (-)
aplnr2 NA coding downstream 404479 22736375 ~ 22739778 (-)
hdac10 hdac10 coding downstream 408430 22726485 ~ 22735827 (-)
yars2 yars2,LOC102786810 coding upstream 2416 23150719 ~ 23156968 (-)
pparab LOC104921011,LOC103371465 coding upstream 12847 23161150 ~ 23191431 (-)
fbln1 fbln1,LOC104955511,LOC103380317 coding upstream 228278 23376581 ~ 23407669 (-)
ppm1h ppm1h coding upstream 355494 23503797 ~ 23537525 (-)
avpr1aa LOC103358863,LOC100711102 coding upstream 403550 23551853 ~ 23556076 (-)
G87400 NA non-coding downstream 306391 22761185 ~ 22837866 (-)
LOC120563633 NA non-coding downstream 461981 22577017 ~ 22682276 (-)
G87329 appl2 non-coding downstream 754041 22387995 ~ 22390216 (-)
G87320 nuak1 non-coding downstream 789061 22287944 ~ 22355196 (-)
G87254 NA non-coding downstream 1038002 22105880 ~ 22106255 (-)
G87464 NA non-coding upstream 816 23149119 ~ 23149344 (-)
LOC120563856 NA non-coding upstream 50269 23198572 ~ 23224641 (-)
G87469 NA non-coding upstream 82935 23231238 ~ 23238532 (-)
G87596 ankrd26 non-coding upstream 481423 23629726 ~ 23630285 (-)
G87614 bmt2 non-coding upstream 532445 23680748 ~ 23737505 (-)
parvg parvg other downstream 437961 22689161 ~ 22706296 (-)
LOC120564428 NA other downstream 777279 22347170 ~ 22366978 (-)
LOC120564778 LOC103358851,LOC101480430,LOC100706913,LOC102797593 other downstream 1404913 21735006 ~ 21739344 (-)
G87140 NA other downstream 1430703 21713042 ~ 21713554 (-)
dnajb9a dnajb9,LOC100706374,LOC102775779,LOC102215328 other downstream 1771748 21369531 ~ 21372509 (-)
LOC120564579 LOC103366737 other upstream 263207 23411510 ~ 23422457 (-)
G87538 NA other upstream 346027 23494330 ~ 23498659 (-)
G87624 LOC103358853,LOC104921025 other upstream 590679 23738982 ~ 23741190 (-)
LOC120563922 NA other upstream 760866 23909169 ~ 23916202 (-)
G87803 NA other upstream 1916449 25064752 ~ 25065488 (-)

Expression


Co-expression Network