map2k2a (map2k2)



Basic Information


Item Value
gene id map2k2a
gene name map2k2
gene type coding
species eurasian perch (Perca fluviatilis)
category of species economic fish

Chromosome Information


Item Value
chromosome id NC_053120.1
NCBI id CM020917.1
chromosome length 41568296
location 26258304 ~ 26268496 (+)
genome version GENO_Pfluv_1.0_2020_eurasian_perch_Genome

Sequence


>XM_039811876.1
TGGATAAGATTGTTAAACTGGACTAACGTTATGCTGTCTATGGATTTGcctcatttaaaaacaacattccGGAGGCGTTATCACAAACTGCAGATGTCGTAAATCTTCCAGTCCGTCCATGTACATCTCCCATGAGATTTCTGCATCTCTCGTATCAACTTGTCAGATGGACTCAGTCTCGCGCTATTTATGAAGAGCTCTCCCTGTGGGTGTCACAGGTCTGATGCCGCAGCTGCTGCTTCCTGTATTGAAGCACCACCAGAACGAGCCAAAGCCCAATTTCGTTTCAGAGCCCCACACCCAGAACTGAAACACGGAGGAATTTGATGCTCGGACGCTGCCGTCCTGCAGAGGGGAAGCTAGCCGAGTCGGTCTGCCGGTGTAGCTGCGGGGAAGACCGCGGCGGCCCGTGTCTTGTGAAAGCGGAGAAGCGAGGAGCTGCACATTAGGACTGAGAGACGCAGGGCACGATTTCTCCAGGAGCTGGTGCTAGCTAGTAGCAGCTAGCTAGTTGGGTAATAGCAGCAGGTAGATAACCCAGAAGAAGCAATAGAACAATAGAAATGTGTTTACTCCAAAAACTATAGATGCACCGGAAAGCGACCTGACCTTTAAAGAGCATCTCGGCATGATACGGTTTAACGTTACCCAAATAGCTGACTGACATGCTACCGAAAGTATACTAACtctttgctaacgttagctagccaaGTTACTAGCCACCAAGAGCTGATCCTGTTGCTTTTTCAAACTTGAGTTTCGAATAAGGAAAAGGCTAGATTAGCAGCCTTCCAGCTCACTGCGGGTTAGTGCATTCTTTGAGAAAGtcatttaggttttttttttattgaaatggcTCCTAAAAGAAGACCCGTTCCCCTGAACATAACGCCCATCGGGGAAGGACAGGCCACCTCAAACACGATTGATGCTGCATCTGAAGCCAACCTCGAGGCCTTACAAAAGAAACTGGGTGAGTTGGACCTGGACGAACAACAGAGGAAACGACTGGAGGCCTTTCTGACCCAGAAAGCTCAGGTTGGGGAGCTGAAGGATGAGGATTTTGACCCCATATGTGAATTGGGTGCTGGAAACGGAGGAGTAGTCAACAAGGTCCGCCACAAACCCTCGGGATTGGTCATGGCTcggaagTTGATCCACCTGGAAATCAAACCTGCCATCAGAAACCAGATTATCAGAGAGCTGCAGGTGCTTCATGAATGCAACTCCCCCTACATTGTGGGCTTCTATGGAGCCTTTTACAGCGATGGGGAGATCAGCATCTGTATGGAGCACATGGATGGTGGATCCTTGGACCAGGTCCTGAAGGAAGCCAGAAGAATCCCAGAAGAAATCCTGGGGAAAGTTAGCATAGCTGTATTGAGGGGATTAGCCTACCTGCGGGAGAAGCACCAGATCATGCACAGAGATGTCAAGCCCTCCAACATCCTGGTCAACTCTCGCGGGGAGATCAAgctgtgtgactttggtgtgaGCGGCCAGCTCATAGATTCCATGGCCAACTCCTTTGTTGGAACGCGCTCCTACATGTCGCCGGAGAGACTGCAGGGCACTCACTACTCGGTTCAGTCTGACGTGTGGAGCATGGGTCTGTCCCTGGTGGAGTTGGCGATTGGCCGCTACCCCATCCCCCCACCAGAAGCCAAAGAGCTGGAGGCCATCTTCGGACGTGCCATTATGGACGGGGCCGAGGGAGAGCCTCACACCAACATGCAGAGGCCCAGACCACCGGGCAGACCCGTGAGCGGTCATGGGATGGACAGTAGACCAGCGATGGCCATCTTTGAACTTTTGGACTACATTGTGAATGAGCCACCCCCTAAACTGCCACTTGGGGTATTCACCAACGACTTTCAAGACTTTGTGACAAAATGTTTGATCAAAAACCCAGCTGAAAGGGCAGATCTGAAGATGTTGATGagTCACACATTCATCAAAAGATCAGAAGTGGAGGAAGTGGACTTTGCTGGCTGGTTGTGCAAAACCATGGGCCTCAACCAGCCCAGTACTCCCACCCGCGGCACTGAGTGAACAGGCCCCCACTGTCCTGACACACCTTCGGTCTTGCTTGCATACACATCAATATACTGCAcctacacacacgtacacacacgtacacaagcCATCCCACACATTGGCactttttttctatctttctctTGGGGAAAACGATCTTCCCCCACATTTATTTCTTCACCAGCAGCAGGGCCCGTTGAGTCATTGTACCCCAGCTTCACCATGCCAGTGTCAAGAGTAGCCACAGCTCATGTTTCCACACTGCAACAGCGGATGTAAAGCACTGAAGGGCTGCCAGTGTGTCAGCTGAATTTGCATTGATTGACAAACTTCTTTTGTATTGTTGAATATACTGTattcatctttttctttttttatggcaACAGTTGATGGCTTGTGTGACTTGTATTTTAACAAATGACCTGCTGTAGAGATTTCCATACAAAGAAATCCGAACATATCACCTACTTGCAAATTCTAAATTGGTTTTATCAAAGGTGAATGCActtattttgatttaaaatccCTTTGTCAAATGTATTCATGCTAAAATGACCAGAGACCTTGCAATTCAATGTAATTAATTGTTAGTAGAGAGTTCagggcgtgtgtgtgcgcgtgtgcgtgtgtgcgtgcgtgcgtgcgtgtgtgtgtgtgtgtgttcattttcactttttggTAAATGAGTGATCACTCTAAAGATCCCTTTGTGAACAATGTCACAAACCAAAGAGGGTACTCATGACTAAATGTTTTCAGTGCGTGATCAGTTTGTTTTCATATGCACATTCATGAACAGTATATTGGTgtattttaa

Function


symbol description
map2k2 Enables several functions, including MAP-kinase scaffold activity; PDZ domain binding activity; and scaffold protein binding activity. Involved in ERK1 and ERK2 cascade; peptidyl-serine autophosphorylation; and positive regulation of nitrogen compound metabolic process. Located in several cellular components, including cytoplasmic side of plasma membrane; microtubule; and perinuclear region of cytoplasm. Implicated in cardiofaciocutaneous syndrome 4 and small intestine adenocarcinoma. Biomarker of breast cancer and glioblastoma.

NR:

description
PREDICTED: dual specificity mitogen-activated protein kinase kinase 2

GO:

id name namespace
GO:0006468 protein phosphorylation biological_process
GO:0005524 ATP binding molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function

KEGG:

id description
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2

RNA


RNA id representative length rna type GC content exon number start site end site
XM_039811876.1 True 2854 mRNA 0.48 11 26258304 26268496

Neighbor


gene id symbol gene type direction distance location
pias4a pias4,LOC102797537 coding upstream 857 26244296 ~ 26257447 (+)
atp8b3 LOC108230572,LOC103354223,LOC102796064,LOC102293201 coding upstream 68382 26143887 ~ 26189922 (+)
lingo3a lingo3,LOC102210007,LOC101476815,LOC102795762 coding upstream 123141 26097785 ~ 26135163 (+)
org NA coding upstream 204683 26050911 ~ 26053621 (+)
amh NA coding upstream 227241 26027275 ~ 26031063 (+)
tcf3b tcf3 coding downstream 38126 26306622 ~ 26339210 (+)
mbd3b LOC103354193,LOC101480296,LOC101063908,LOC104920733,LOC108230843,LOC105938962,LOC103399996 coding downstream 73946 26342442 ~ 26350427 (+)
si:dkey-110c1.10 LOC100701936,LOC102208033,LOC101482435,LOC102800276 coding downstream 82103 26350599 ~ 26379944 (+)
celf5a celf5,LOC102777648 coding downstream 253848 26522344 ~ 26724401 (+)
polrmt polrmt,LOC101481838 coding downstream 609812 26878308 ~ 26935883 (+)
G98384 NA non-coding upstream 64215 26191868 ~ 26194089 (+)
G98363 NA non-coding upstream 121674 26135237 ~ 26136630 (+)
G98312 NA non-coding upstream 333254 25884516 ~ 25925050 (+)
LOC120565749 NA non-coding upstream 420557 25786325 ~ 25837747 (+)
G98280 NA non-coding upstream 517755 25739131 ~ 25740549 (+)
G98494 NA non-coding downstream 229536 26498032 ~ 26498261 (+)
G98500 NA non-coding downstream 242688 26511184 ~ 26511527 (+)
G98546 NA non-coding downstream 602848 26871344 ~ 26871564 (+)
G98552 hcn2 non-coding downstream 672416 26940912 ~ 26949064 (+)
G98544 bsg non-coding downstream 724402 26992898 ~ 26998445 (+)
oaz1a oaz1,LOC104950707 other upstream 218438 26034751 ~ 26039866 (+)
dot1l dot1l,LOC102793654 other upstream 238933 25991506 ~ 26019371 (+)
slc35a3a slc35a3,LOC101471768,LOC102790943,LOC100705874,LOC108230529,LOC103354215,LOC106515047 other upstream 519515 25730225 ~ 25738789 (+)
G98194 NA other upstream 711215 25532825 ~ 25547089 (+)
elovl1b LOC106963699,LOC101078639 other upstream 1384388 24852287 ~ 24873916 (+)
zbtb7a zbtb7a other downstream 14556 26283052 ~ 26295382 (+)
LOC120565098 NA other downstream 71047 26339543 ~ 26342293 (+)
micos13 LOC104918748,LOC103371279,LOC104964520,LOC106536194 other downstream 523233 26791729 ~ 26796287 (+)
si:ch211-212d10.2 LOC103371119,LOC104950605,LOC100693321,LOC101487565,LOC102778050 other downstream 1104313 27372809 ~ 27377054 (+)
ncanb ncan,LOC104966594,LOC107554802 other downstream 1391200 27659696 ~ 27832855 (+)

Expression



Co-expression Network