tdo2a (tdo2)


Basic Information

Item Value
gene id tdo2a
gene name tdo2
gene type coding
species eurasian perch (Perca fluviatilis)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_053121.1
NCBI id CM020918.1
chromosome length 40300294
location 29867532 ~ 29874648 (-)
genome version GENO_Pfluv_1.0_2020_eurasian_perch_Genome

Sequence

>XM_039812697.1
TATCCTCAAGAGTGATTGGATGGGGTGAGTCTTTAAAAGTCTGGATTGCGTTGAAGACAATTTTAGTTAATGTTGTCAAGGAAGAAGAACACATCTGTGCCACAACTGAAGTCATGAGTGGATGTCCATACTTTGAGAAGAGGCATTTGTTATTCAAAAACAAGCCTCCCAAAACAGAGGAAGATGAGGATGCCTCTCAGGCAGGCGTTAACAAGGCCAGTAAAGGAGGAATCATCTATGGAGACTACCTGCAGCTCGACAAAATCGTCTCAGCCCAGGTGTTGCAGAGTGAAGTAAAGGGCAATAAAATCCATGATGAGCACCTCTTCATCGTCACCCATCAAGcATATGAACTGTGGTTCAAACAGATTTTGTTTGAACTTGATTCGGTGCGACATCTCTTCATCAGTGGACATgTCAGAGATGAACGCAACATGCTGAAAGTCAACAATCGCATCCACAGGATTGTGATGATCTTTAAGCTGTTGGTCGACCAGTTTGCGGTTTTGGAAACAATGACAGCCTTGGACTTTTTTGACTTTAGgGAATACCTGGCTCCAGCCTCTGGATTCCAAAGCCTTCAGTTTCGGATCTTGGAGAACAAAATTGGGGTCCCGGACAACCTGAGGGTTCCATACAACAGACGCCATTACAGGGACAATTTCAAGGGTCATGAGAGTGAGATGCTGCTCGCCACAGAACAGGAGCCGACACTTTTAAAACTAGTCGAGGAGTGGCTGGAGAGAACTCCTGGCTTGGAGGTGGACGGATTCAATTTCTGGGAAAGGCTGGAAATCAATATTTTTGATGGGCTGAAACTGGAAAAGGAGAAAATCGAGaaaatggaaGATTCTGAGGACAAGGAAGAAATGATGGCTGAACTGGTCAAACAGAAAGAGCTGTTTACGTCACTCTTTGATGAAAAGCGACATGACCATCTCCTTAGCAAAGGCGAGAGGCGGCTCTCTTACAAGGCTCTCCAAGGTGCCCTGATGATCAACTTCTACAGGGAAGAGCCGAGGTTCCAGGTTCCTTTCCAACTGCTCACATCTCTCATGGATATTGACACCCTCATGACAAAATGGCGATacAATCACGTATGCATGGTGCATCGTATGATTGGCAGCAAAGCCGGCACAGGGGGTTCATCTGGCTACCACTACCTGAGATCTACTGTCAGTGACCGCTACAAAGTGTTTGTGGATCTGTTCAATCTGGCAACGTTCCTGGTGCCTCGCCACTGGGTGCCCAAGCTAAATCCCAACATTCACACGTTCCTCTACATGGCCGAATGTTGCGACAGCTCCTACTGCAGCAGTGAAGACTCAGACTAGAGGAATCAATCCCAGTCGTCTGTCCTGGCTTACATTTTCACCGTAACTGACCTCAAAACAGTAGATCCGTTGCACAGCTGAAAGGTTTTAGTAAGAGGTGCATACAGTaagatgatgaagaaaactcttaaaacacaggaaaatggaatttttgtttgtttgttttgtttttttttacagttgaaaAAAGAGTGAAGCATGGCACAGGGAGGGGTCATTTAACATAGGTGACAATCTAAACCACCAAAATATCCATTAGGGAGAGACACTTGATACCATGATAGTATTATTGGTTGGgatttaaataattttagtatttggattgtattttttaatgtaaaatatatatatataatttttttttcatctcattGTGACACTAAAAGCATGCCAAATATCCTACACTTATGTTAACAAAGAACAGTAACAGAATTTAGCTTATTAGTTACATCAGACTGCAGCACCAAGGTTTATACGCCAGAATCTTGTGACGCAGTGTCTGACCCTGAACAATTCAAATGGCCAAATTAGACAATTTTGCTCTAATTTCTAATCTTAACCGGTGACAAAGTATAGCAGATGGCTACTTGATAAAATTtgctttgatgtttttttttcagtacaATTATGTAAATTCCCTGTGACTGACCTGAAAG

Function

symbol description
tdo2 Enables heme binding activity; identical protein binding activity; and tryptophan 2,3-dioxygenase activity. Involved in protein homotetramerization and tryptophan catabolic process to kynurenine. Predicted to be located in cytosol. Implicated in Gilles de la Tourette syndrome and familial hypertryptophanemia.

NR:

description
tryptophan 2,3-dioxygenase A-like

GO:

id name namespace
GO:0055114 oxidation-reduction process biological_process
GO:0019441 tryptophan catabolic process to kynurenine biological_process
GO:0004833 tryptophan 2,3-dioxygenase activity molecular_function
GO:0020037 heme binding molecular_function

KEGG:

id description
K00453 TDO2, kynA; tryptophan 2,3-dioxygenase

RNA

RNA id representative length rna type GC content exon number start site end site
XM_039812697.1 True 1990 mRNA 0.42 12 29867532 29874648

Neighbor

gene id symbol gene type direction distance location
asb5a asb5,LOC103355623,LOC101464329,LOC100697054,LOC107095814 coding downstream 8420 29852829 ~ 29859112 (-)
spata4 NA coding downstream 14848 29847910 ~ 29852684 (-)
gpm6aa gpm6a,LOC103355621,LOC104917912 coding downstream 26094 29819789 ~ 29841438 (-)
lrit3a lrit3,LOC100696521 coding downstream 49241 29811122 ~ 29818291 (-)
egf egf coding downstream 59494 29781903 ~ 29808038 (-)
si:dkey-237h12.3 tenm3 coding upstream 6542 29881190 ~ 30028138 (-)
neil3 neil3 coding upstream 216300 30090948 ~ 30102919 (-)
pdgfc pdgfc coding upstream 265161 30139809 ~ 30184692 (-)
ppid ppid coding upstream 663179 30537827 ~ 30548407 (-)
LOC120566929 clg2h4orf45,LOC104948239,LOC102200624,LOC101472142 coding upstream 678528 30553176 ~ 30555189 (-)
G108600 NA non-coding downstream 91111 29723824 ~ 29776421 (-)
LOC120567321 NA non-coding downstream 116996 29553435 ~ 29750536 (-)
G108560 NA non-coding downstream 593578 29273594 ~ 29273954 (-)
LOC120567081 NA non-coding downstream 938627 28833175 ~ 28928905 (-)
G108524 LOC104954097 non-coding downstream 1186433 28678279 ~ 28681099 (-)
G108702 NA non-coding upstream 401216 30275864 ~ 30282627 (-)
G108718 NA non-coding upstream 512873 30387521 ~ 30387854 (-)
G108722 NA non-coding upstream 528012 30402660 ~ 30403036 (-)
G108772 rapgef2 non-coding upstream 778222 30652870 ~ 30654526 (-)
G108785 NA non-coding upstream 858911 30733559 ~ 30733770 (-)
cxcl14 cxcl14 other downstream 1059538 28797298 ~ 28807994 (-)
fam13b fam13b,LOC102777128 other downstream 1072024 28714863 ~ 28795508 (-)
LOC120566547 NA other downstream 1828832 28024570 ~ 28038700 (-)
G108433 neto1,LOC101071133 other downstream 1844303 28021737 ~ 28023229 (-)
LOC120566991 NA other downstream 1911838 27952256 ~ 27955694 (-)
gask1b fam198b,LOC102776406 other upstream 472330 30346978 ~ 30356856 (-)
G108777 rapgef2 other upstream 786264 30660912 ~ 30661623 (-)
G108781 rapgef2 other upstream 794883 30669531 ~ 30670849 (-)
LOC120566409 limch1 other upstream 1510442 31385090 ~ 31423481 (-)
LOC120566557 limch1 other upstream 1545231 31419879 ~ 31485976 (-)

Expression


Co-expression Network