npc1 (npc1)


Basic Information

Item Value
gene id npc1
gene name npc1
gene type coding
species eurasian perch (Perca fluviatilis)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_053122.1
NCBI id CM020919.1
chromosome length 39550354
location 20507410 ~ 20523539 (+)
genome version GENO_Pfluv_1.0_2020_eurasian_perch_Genome

Sequence

>XM_039815168.1
ATTCGACGAAGAAGAAACCATTCACAAGATTATGCGAAACTTGTTGTGGACTGTCACTTCGATACTATCGTTTCAGTAAGAGGGATGGGAGTCCTACCAGGGAGAAGCCTTTTATGcatactttttttaattataatcaTCTCAGAGGGACATTTTCGATGGGTTGAGGCCCAGCACTGTGTGTGGTATGGTGAGTGTGGGGAATCCGTAAAGGTGCCTGGAAAAAAGTACAACTGCAACTACACAGGTCCTCCCCGCCCCCTAGACGCTAAGGGCTATGACCTTCTCACGGAGCTTTGTCCTGGATATGACTATGGAAGCAAAAGCCTCTGCTGTGACGTTAACCAGTTGCAAACACTCAAAGGGAGTCTCCAGCTGCCCCTACAGTTCCTGTCTCGGTGTCCTGCCTGTTTCTTCAACTTGATGAACCTGTTCTGTGAGCTTACATGCAGCCCTCACCAGAGTCAGTTCATGAATGCCACGAAGATCGACAAGACCAATGTAGTGGAAGTCCAGTACTATATTGGACAGACATTTGCTAATGCCATGTACAATGCCTGTAAGGACGTCCAGGCACCATCCAGCAACGTAAAGGCCTTATCACTGCTGTGTGGGAAGGATGCAAAGGACTGCAATGCTACCAACTGGATCCAGTATATGTTTGATATTAACAATGGACAGACTCCCTTTCCTATCATCCCAATATTCTCAGATGTCCCAGTGTCTGGTTACACTCCCATGAACAACAAAACATATGCCTGTACAGAGGGCCTGGAGGACGGTTCAGGTCCCTGCTCCTGTCAGGACTGCACAAAGGCCTGTGGCCCCAAACCTGTGCCCCCCCCTGTCCCCCCTCCCTGGACAATCCTTGGTATCGATGCCATGACTCTCATCATGTGGATCTCTTACATGGCCTTCCTGCTTATCTTTATTGGAGCTGTACTGGGAGCTTGGTGTTACAGGAAAAGGACCATCATGTCTGAGTATGGCCCCATATTGGACAGCAATAACCCACTGTCTCTCAACAGTGATAATCCTGACCAAGTAAATGCATCATGCTGTGAAACATTGGGTGAGCGATTCGAGAATGCTCTGCGGACCCTCTTCAGCTCCTGGGGTTCCTTCTGTGTGCGGCATCCTTCTGTGGTCATACTGGGCAGCCTGATACTGGTGGTCTCCGCCTCTGGGGGCCTGGTCTATATGCGCATCACCACAGACCCTGTTGAGCTGTGGTCATCTCCCACTAGCCAGGCTCGTCAAGAGAAGGACTACTTTGACAGCCACTTTGGACCCTTCTTTAGAACTGCGcagctcatcataaccactccACTCAATGGAAGTTTCACCTACTCCCCATACTTTGGAGGATCAGATGTCCCATTTGGAGCCATCCTGGACAAAGATATCCTGCACCAGGTGCTGGATCTGCAGCTTGACATTGAAGGCATTGTAGCCACATATGAGGGCCAAACCGTCACCCTTAATGACATCTGCTTGGCTCCGCTGGCCCCGTACAATAACAACTGTACCATCTTGAGTGTCCTCAACTACTTTCAGAACAGCCATGCTGTGCTGGACCACACCATAGGAGACGATTTCTTTGTGTATGCTGACTTTCACAGCCACTTCCTCTACTGTGTCAGTGCACCAGCATCCCTAAATGACACCACCCTCCTCCATGACCCCTGTTTAGGCACTTTTGGCGGCCCCGTCTTCCCTTGGCTGGCCCTCGGGGGTTACGATGAAACCAACTACAACAATGCCACTGCTCTTGTGATCACCTTCCCACTCAACAACTACCTGAATGACTCAGTTAGGCTGGGCAAAGCTCTGGCATGGGAGAAAGAATTCATCAAATTCATGAAGAACTTCAAAAACCCTAACCTGACCATAGCCTTTAATGCTGAGAGGAGTATTGAAGATGAAATAAACAGAGAGAGCAACAGTGACATCAGCACCATAGTAGTCAGCTATGCCATCATGTTCATCTACATCTCCCTGGCCCTGGGTCACATCCACAGCTGCAGGAGACTGATGGTGGACTCCAAGATTTCTCTGGGTATAGCGGGTATCCTGATTGTGCTCAGCTCTGTGTCCTCATCACTGGGGATCTTCAGCTATTTTAACATCCCCCTTACCCTCATTGTGATTGAGGTCATTCCTTTCCTGGTGCTGGCCGTTGGAGTGGACAACATCTTTATTATAGTACAGACCTATCAGAGGGATGAGCGGATGCCCCAGGAGGAACTTCACCAGCAGATTGGTCGTATTCTTGGAGACGTAGCCCCCAGCatgttcctctcctccttctcagAGACAGTTGCCTTCTTCCTGGGAGCCCTGTCCAACATGCCCGCAGTGAGGACTTTCTCTCTGTTTGCTGGCTTGGCTGTTTTTattgatttcctgttgcagaTCAGTTGCTTTGTCAGCTTGCTCGGCATGGACGCCAGGAGACAGGAGGGGAATCGACTCGACATCTTTTGCTGTGCGAAGCTGCCGGAAGCTCAGGAAACTAAGACGGACAGCTTCCTCTTCCGTTTTTTCAAGAAAGTCTTTGCTCCATTCATCCTCAAAGAGTGGGTGCGACCGATCATAGTGGCAGTGTTTGTGGGAATACTCTCCTTTAGTATTGCTGTGGTGAATAAAGTAGAGATTGGACTGGACCAGAAACTCTCCATGCCGGATGACTCGTACGTCCTGGACTATTTTAAGAACATGAGCATGTATCTCCACACTGGAGCTCCAGTGTACTTTGTGGTAGAAGACGGTCTTAACTACAGTAGCCCAGAAGGCCAGAATGTtgtgtgtggaggagtgggCTGCAACAACGACTCTCTGGTCCAGCAGGTCTACAGCGCCTCACTCATCAGCAACTACACAACCATCGCCTTCACACCGTCCTCTTGGCTCGATGACTACTTTGACTGGGTGAAGCCGCAGTCCTCCTGCTGTCGATACTACAACACCAGTGGGGCTTTCTGCAATGCCTCTGTGGTAAATCCCTCCTGCGTACACTGTCGGCCCATGACTCCCAGTGGTAAGCAGCGGCCAGAAGGAGAGGACTTCATGCATTTTCTACCCATGTTTCTGTCAGACAATCCAAACATCAAGTGTGGAAAAGGCGGCCACGCGGCGTACGCCACAGCAGTTGACCTGTATCCCAACAACACGGGGGTCGGAGCCACTTACTTCATGACTTACCACACCATCCTGAAAGAATCCCCAGACTTCATAGATGCTTTAAAAATGGCCCGAATCCTGGCTGACAATATCAGTCAGTCCATGGATCACAAAGTTTTTGCCTACAGCGTCTTCTATGTGTTTTACGAGCAGTACCTCACCATTGCATATGACACAGCTCTGAACTTGAGCGTGTCACTGGCATCCATATTTGTTGTGACGACGGTGTTGCTGGGCTTCGAGCTGTGGTCGGCTGTGATCGTCAGCATTACCATCGGCATGATCCTGGTCAACATGTTCGGCGTCATGTGGCTGTGGAACATCAGCCTCAACGCAGTTTCCCTTGTGAACCTGGTCATGTGCTGCGGTATCTCGGTGGAGTTCTGCAGTCACATTGTGCGAGCGTTTTCCATCAGTGTGAAGAAGAACAGAGTGGAGCGGGCTGAGGAGGCCCTGGCTCACATGGGCAGCTCTGTATTCAGTGGGATCACATTAACAAAGTTTGGAGGTATACTAATCCTGGCGCTTTCCAAGTCGCAGATCTTCCAGGTCTTCTACTTCAGGATGTACTTGGCCATAGTGTTGCTGGGGGCCACGCACGGCCTCATCTTCCTCCCTGTACTGCTCAGTTATATCGgtcCTTCGGTGAACAAAGCAAAGGTGTTTGCTGCTAACAAGCGCTATGCTGGTACAGAACGGGAGCGCCTCCTCAACTACTAGCAGGCTGTTTGGGAACAACAATGAACAATGAACTATGAACTATTTGTCTGAAagggactgtgtgggtgtgcgcGCAAGCCGTTTCTGTGATTACTGACACACTCATCACTGTTGACACTACTATGCACGGATTTAACTCAGGAATATACTTGGGAGTAGAAGTGCCAGAGGCCGTGTCCAACTGTAAAATTATTGATTTTCCTCAGAAGACTTTGGACCCCCACCATTCGTCCTCCTCACACTACGGGACAAGCCTGACTTCTGCATTTGAAGCACGGGTGACATACCACTGAACAAAAAAATGCACTGTCTGCTTTGACAGTGTGGAAGTAGGAGAGACACCACCCCCAACATCAGTTACAGACCAACTCTGTCAGTTCCATATGCTATGAGCTATTTTGATTTGGGAAAAAACTCAAAAGGGTAAAACTGGaccgttttttttccccatgattttaaatatatttaccaGGATAAAAATCAAATGAGTAATGGtaaattattttgaaatttttacTTAACTTACGTGGGACTTTTGTAGAACTGTTTgatattatgaataatttgttTACTGGAATAGAACATACAGTGGAGCTGAGAGATAACTATTTTGATATGAGAAGGGCCTCATAATACCTGGTATTAACATGTATCGTATCCCGGGGCTGTGTCTACATACTGTATTATAAATCAGGTCAGCTAGTTGTAGCATTTTCACCTAGCAATAATGGGTTTCCTGTGTATTTGCACAGTAATGTTTTCACTGCAGCACACTGGATTTGAATGTTGAAGGTTTTTGGGCGTGTTCACATCCATGTTGGGAGAGCAGTGTAGGAATTGTAGCCCCTTTTTACCTTTCGtagtatacatttaaaaaaaaaaaaggctacaaTTTCTAAAtggacatggatgtaaactCCATCAAAGCTGAAACTTCACagtaattgttttatttaaaaatcagAGAATGGGAATGCAGAGCCAAAAACAGTGCAAGTACTAGCCCTTAGGTGTTGTGTGTTGCTCTCCAAACTGCATCCtgctgtttcttttattttcacattggTTTTTACATGATCTGGTGCAACATTTCATTTTAGAGCTAGTTAGTGTATCTTAAGTGTCCTTTTAAGGTGTTTGCATGCTTTTACAAAAAACTCTGTGTGACATCAGTCAAGACACATGTTAATGCCAGGTGAACAGGATGCTATCAGGCCAATAATGGGTTTTACATTGAAGTGTAAGTGAGACATTTTGCAGTTACTGAACAGAACATTTGTTGCATTAAGAGGTAAAGAGACGAAGCTTTACATTTCACTATAATGGGACTAATTTAGATGTATTTCTACGGTATGtcatttactgtgtgtgttgagaCAGAATACTGTAGCTTGGCTGAATGGTACAGGTCTGAGTTTTTCATTCAAACACATTTaagttattctttttttatttagttaacTATTAACATTTTGTTACCATGCAAAAACACTTCCAGTGACCTTGAAAGTAAAGGATCCTCCCAGCAACATGTTCAGCTGCAGCTCAACGTGTCTGAGATTGGAGCTAGTCGAGATGATGACACATCCAGGTGGTGTGATCCCACCAGATTAATGTGAATAGGGTTGTACCATCATTGGAACAGGATGTTATGTTTAGGTTTTTTGTTTCCCACGAttcagttatttttatttttattttttatttttttattttttttctttggaatGTAAGAAAGAATTGTGTTAATTAACAgtttaatgtaaaaacaaatgtttatgAGCAACCGACTGAAGAAGTTGTAACGAATAACGAAGAATTGTGCTTGCTAACAGTGCTGTGCATTGACATGGACAAATCATCTCTGCATTGAAGAATATGATTGTGGGGGAAAAAACCTAAACCAAGTATAGGAATACTTTAGTTTTTAACAATTTTAACACAATATTAAATAGTTCTCAGAAAAATA

Function

symbol description
npc1 Predicted to enable lipid transporter activity. Acts upstream of or within several processes, including cholesterol homeostasis; epiboly involved in gastrulation with mouth forming second; and megakaryocyte development. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including heart; liver; nervous system; pleuroperitoneal region; and yolk syncytial layer. Used to study Niemann-Pick disease type C1. Human ortholog(s) of this gene implicated in Niemann-Pick disease type C1. Orthologous to human NPC1 (NPC intracellular cholesterol transporter 1).

NR:

description
Niemann-Pick C1 protein-like

GO:

id name namespace
GO:0030301 cholesterol transport biological_process
GO:0007165 signal transduction biological_process
GO:0016021 integral component of membrane cellular_component
GO:0008158 hedgehog receptor activity molecular_function

KEGG:

id description
K12385 NPC1; Niemann-Pick C1 protein

RNA

RNA id representative length rna type GC content exon number start site end site
XM_039815168.1 True 5872 mRNA 0.46 25 20507410 20523539

Neighbor

gene id symbol gene type direction distance location
egfra LOC103369338 coding upstream 3134 20461791 ~ 20504276 (+)
c1ql3b LOC108241646,LOC102783794,LOC101484294,LOC102201850,LOC103369334 coding upstream 98377 20407668 ~ 20409033 (+)
gpt LOC102200225,LOC103359759,LOC101485501,LOC100690242,LOC102299610,LOC102784352 coding upstream 111192 20376975 ~ 20396218 (+)
fuz fuz coding upstream 128103 20377158 ~ 20379307 (+)
ssx2ipa ssx2ip,LOC103359758 coding upstream 134265 20366760 ~ 20373145 (+)
abhd3 abhd3 coding downstream 153818 20677357 ~ 20689630 (+)
rock1 rock1 coding downstream 217722 20741261 ~ 20779745 (+)
usp14 usp14,LOC102778130 coding downstream 258716 20782255 ~ 20792499 (+)
pth1r pth1r coding downstream 411896 20935435 ~ 20983609 (+)
LOC120567629 NA coding downstream 493363 21016902 ~ 21019325 (+)
G116327 NA non-coding upstream 184869 20322288 ~ 20322541 (+)
G116322 NA non-coding upstream 192139 20314888 ~ 20315271 (+)
LOC120567788 NA non-coding upstream 303672 20202125 ~ 20203738 (+)
G116216 NA non-coding upstream 604591 19902243 ~ 19902819 (+)
G116215 NA non-coding upstream 621711 19884595 ~ 19885699 (+)
LOC120567944 NA non-coding downstream 125066 20648605 ~ 20654150 (+)
G116461 NA non-coding downstream 168080 20691619 ~ 20691985 (+)
G116463 NA non-coding downstream 169348 20692887 ~ 20693141 (+)
G116464 NA non-coding downstream 169881 20693420 ~ 20696473 (+)
G116465 NA non-coding downstream 173365 20696904 ~ 20699209 (+)
LOC120567833 gbg5 other upstream 131777 20373227 ~ 20375633 (+)
emilin2a NA other upstream 1042029 19447011 ~ 19465381 (+)
LOC120568770 NA other upstream 1455168 19017039 ~ 19052242 (+)
LOC120568911 NA other upstream 1781963 18720365 ~ 18725447 (+)
LOC120568691 NA other upstream 1833270 18660429 ~ 18674140 (+)
LOC120568904 crhr2,LOC101476678,LOC102776588 other downstream 359078 20882617 ~ 20915322 (+)
LOC120568354 NA other downstream 1347414 21870953 ~ 21897391 (+)
LOC120567968 NA other downstream 2084510 22608049 ~ 22620131 (+)
LOC120568311 LOC103368946,LOC103142996,LOC106925933,LOC104929332 other downstream 2117971 22641510 ~ 22681293 (+)
kdsr kdsr,LOC102792240 other downstream 2910086 23433625 ~ 23440843 (+)

Expression


Co-expression Network