insra (insr)


Basic Information

Item Value
gene id insra
gene name insr
gene type coding
species eurasian perch (Perca fluviatilis)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_053122.1
NCBI id CM020919.1
chromosome length 39550354
location 18394984 ~ 18453965 (+)
genome version GENO_Pfluv_1.0_2020_eurasian_perch_Genome

Sequence

>XM_039815220.1
ATGGGGTATTATTCCGAGTCAGTTATGTGGCTCCGGACtttgtgcttgtgttttgttttgaccGCTGTCTGCTTTGTGATGAGCTGTCAACGAGCAAGTGGAGAGGTTTGTCCAAGCAAGGACATCCGCAACAATGTGACCAATCTACATACGCTAGAGAACTGCACCGTGATCGAAGGCCACCTGAAGATCTTACTCATGTTCAGGACCAAGCCCGAAGATTTCCGAGGCCTCAGTTTTCCCAAACTGACAGTGGTCACTGACTACCTGTTGCTCTTCAGAGTTTACGGCCTGGAGACCCTCAGCGATCTCTTCCCCAACCTAACTGTCATCAGAGGCAATAACCTGTTCTTCAACTATGCCCTAGTAATGTTCGAGATGCTCCAACTGCGAGAGATCGGCCTCCATAGCTTGATGAACATCACCCGAGGAGCCGTGAGAATTGAGAAGAACCCAGATCTCTGCTATCTCTCCACTCTGGACTGGTCCAAGATCCTGGACACAGGGGAGGACAACTACATCATGGCTAACAAGAACGACAGAGAGTGTGGAGACGTCTGCCCCGGGGCGGCCAGTGGAAAGACCACCTGCCAGACCACCACCATCAACGGACACTTCAGTGAACGCTGCTGGACTCAGAACCACTGTCAAAGAATGTGCCCTGTTCATTGTAAACATCGAGCCTGCACCAAGGACGACCAGTGCTGCCACGACCAGTGCCTGGGCGGCTGCCGGAAGCCCCACTCATCCAGCCACTGCGTGGCCTGCCGCGGCCTCCAGCACGAGGACAGTTGTGTTGAGCGCTGCCCTGAAAATCACTTCACCTACAAAGGCTGGCGCTGCGTCTCCTTCGCCTTCTGCCAGGATCTCCACAACAGATGCAAGCGGGAGAAGGAGCACAGCAAGAACCCCGACTGCCACGAGTATGTCATACACAATGGTGCCTGCATCCCTGAGTGTCCCTCTGGCTACACGACCATCAACTCCTCCGCGCTCAACTGCACTCCCTGTGCAGGGCTGTGTCCCAAGGTATGTATGGGTTTAAAAACTGTGGACTCAGTCACTGCTGCCCAGGCTTTGAGAGGCTGCACAGTTCTCAACGGGAGCCTGGTCATCAACCTGCGGGGAGGAAACAACATAGCAGCTGAACTGGAGGCCAGTCTGGGCCAGCTGGAGGAGATCACTGGCTACCTGACAGTGCGACGTTCCTACGCCCTCGTATCCCTCTCTTTTTTCCGCAAACTCCGTGTTATTCGTGGAGAGGAACAGGAAATCGGGAATTACTCATTCTATGCCCTGGACAACCAGAACCTGCGGCAGCTCTGGGATTGGTCCAAACACAAGCTGACCATCCTGCAGGGACGCATGTTTTTCCACTACAACTCCAAACTCTGCATGTCTGAGATCCGCAAGATGGAGGAAGTGACTGGGACCAAAGAGCGGCAAGTCAAGAACGACATCGCCTCCAAGACCAATGGAGACCAGGCCTCATGTGAGAACCATGTGTTGAAGTTTACCCTGATTCGAACCATGAGCGATAAGATAATGGTCAAGTGGGAACCCTTCTGGCCTTCAGACTTCAGAGACCTGCTGGGCTTCATGGTGCTCTACAAAGAAGCACCTTTTCAGAACGTAACCGAGTTTGACGGGCAGGATGCCTGCGGCTCCAACAGCTGGGTGATTGCTGACGTAGACCCTCCTCGTCGAGCCACAGAGGGGGACAAAGAGCAGTTAGAACCAGGTCATCTCATCCTACCACTGAAGCCCTGGACGCAGTACGCCATTATGGTGAAAACCCAGCTCTCTGCCTCTGATGAGCACCAGGTCCACGGAGCCAAGAGTGAGATCATCTATGTTCGCACCAACGCCACCAAACCCTCAGTCCCACTGGACCCCATTTCCTCGTCCAACTCTTCCTCCCAGATCATCCTCAAGTGGAAACCTCCCAACGACCCCAACGGCAACATCACTCACTACCTGGTCTTCTGCCAGCGCCAGCCTGAAGCCAGCGAGCTTTACAAGTTTGACTACTGTCAAAAGGGGATGAAGTTGCCGTCACGAGTGCCCACTCAGGTTGACAGTGACGAGGAGCAGAAATGGAACCAGACGGAGGAGCAGGGCCCGGGGACACGATGCTGCGCCTGCCCCAAAACCGACAAGGAGCTcaagaaggagaaagaggacTCAGAGTACCGCAAAACCTTTGAGAATTATCTCCACAATGAAGTCTTTGAGATCAAACGCTCAAGAGAGCGACGCTCTGTGGTGGGCATCGCCAACCAAACACAACCCTTCCTCACCACTGCCCCCAGCCCTCCCCAGGGCACAGGCATCCCCGAGGACGAGGAAACCTTTGAAAGCACAAAGACAGTGGTTACCGTCCACGCCCACGCCAAGGAGTCCACTGTCATTTCCAGCCTGCGCCACTTCACCAGCTACCAGATCGAGGTCCACGCCTGCAACCACCTGACCGATCCGGCCCGCTGCAGCATGGCAGCGTATGTCAGTGCCCGCACACTGCCTGAAGACAAAGCTGATGACATTGAGGGTCCCATCAGATACGAGGTGACAGAAAATGCAGTGCACGTCACGTGGCAGGAACCGGTGTCCCCAAATGGTATGATCATCCTGTACGAGGTCAACTACAAGAGGCTGGGAGACACAGagGAGCTGCACTACTGCGTGTCAAGGAACATGTACAGAGATACCCGGGGCTGCAAGCTGAAAGTGATGCATCCTGGGAACTACACGGTGAGGATCAGGGCCACCTCGCTGGCCGGGAACGGATCCTGGACCGAACCCACGTACTTCTACATCCAGGATTCAAGCGATCCTCTCTACGTCGTGAAGATCATTATTGGACCGATCATCTGCTTTGTCCTGCTGCTGTTTGTGGCCGTGGCAGGATTCGTCGTTTTCAGGAAGAATCAAACTCAAGGACCTAGTGGTCCCATCTACGCCTCTTCAAACCCAGAGTATCTCAGTGCTAATGACATGTATGAGGAGGACGAGTGGGAAGTGGGCAGAGACAAGATCCACATTTTGAGGGAACTGGGTCAGGGCTCCTTCGGCATGGTCTACGAGGGCATCGCCAAGGACATCATCAAGGGCGAGGGGGACATGCACGTAGCGGTGAAGACGGTGAACGAGTCGGCCAGCCTGAGAGAAAGAATTGAGTTCCTGAACGAGGCCTCGGTCATGAAGGCCTTCAGCTGCCACCATGTGgtgCATCTGCTGGGTGTTGTGTCTAAAGGCCAGCCCACCCTGGTGGTGATGGAGCTGATGACCCACGGAGACCTGAAGAGCTTTCTGCGCTCTCTACGACCGGACGCTGAGAACAACCCCGGGCGTCCACCGCCCACTCTAAAGGAGATGATCCAAATGGCCGCTGAGATCGCCGACGGCATGGCTTACCTTAACGCTAAGAAGTTTGTCCACAGAGACCTGGCAGCCAGAAACTGCATGGTAGCTCACGATCTTACCGTCAAAATAGGAGACTTTGGAATGACTAGAGACATCTACGAGACGGACTACTACAGGAAGGGAGGGAAGGGCCTGCTGCCCGTCCGGTGGATGGCACCTGAGTCTCTGAAGGACGGGGTCTTTACCGCAAATTCAGACTGCTGGTCATTTGGGGTTGTGCTTTGGGAGATCAGCACGCTGGCCGAGCAGCCGTACCAGGGCCTGTCTAACGAGCAGGTCCTCAAGTTTGTCATGGACGGAGGCTACCTGGACCGGCCAGACAACTGCGCTGACAGACTACACAACCTGATGCAGATGTGTTGGCAGTACAACCCCAAGATGCGTCCTGCCTTCCAGGAAATCATTGAGATGCTACGCGAGGATCTGCATCCTTCCTTCCAGGAGTTGTCCTTCTTCTACAGTGAGGAGAACAAGCCACCCGAGACCGAAGACTTTGACCTGGACATGGAAAACATGGAGAGCATCCCACTGGACCCATCGTAACCCTA

Function

symbol description
insr Enables several functions, including insulin-like growth factor binding activity; peptide binding activity; and purine ribonucleoside triphosphate binding activity. Involved in several processes, including positive regulation of cellular metabolic process; positive regulation of intracellular signal transduction; and protein phosphorylation. Located in caveola. Is integral component of plasma membrane. Part of insulin receptor complex. Colocalizes with nuclear envelope and nuclear lumen. Implicated in Donohue syndrome; diabetes mellitus (multiple); familial hyperinsulinemic hypoglycemia 5; and reproductive organ cancer (multiple). Biomarker of Alzheimer's disease; breast cancer; hepatocellular carcinoma; renal cell carcinoma; and seminoma.

NR:

description
PREDICTED: insulin receptor

GO:

id name namespace
GO:0018108 peptidyl-tyrosine phosphorylation biological_process
GO:0048589 developmental growth biological_process
GO:0046777 protein autophosphorylation biological_process
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway biological_process
GO:0009790 embryo development biological_process
GO:0016021 integral component of membrane cellular_component
GO:0043548 phosphatidylinositol 3-kinase binding molecular_function
GO:0043560 insulin receptor substrate binding molecular_function
GO:0005524 ATP binding molecular_function
GO:0004714 transmembrane receptor protein tyrosine kinase activity molecular_function

KEGG:

id description
K04527 INSR, CD220; insulin receptor

RNA

RNA id representative length rna type GC content exon number start site end site
XM_039815220.1 True 3971 mRNA 0.55 21 18394984 18453965

Neighbor

gene id symbol gene type direction distance location
mfsd14a2 mfsd14a,LOC103353046,LOC100705862,LOC102785602 coding upstream 10013 18360882 ~ 18384971 (+)
myo9b NA coding upstream 34754 18328258 ~ 18360230 (+)
loxl5b NA coding upstream 101944 18288083 ~ 18293040 (+)
LOC120568295 nmrk2,LOC106914787,LOC103146068,LOC102216674,LOC106516864,LOC103479788,LOC107094235,LOC102787357 coding upstream 113164 18279102 ~ 18281820 (+)
LOC120568293 LOC103353052,LOC101477959 coding upstream 117981 18265917 ~ 18277003 (+)
arhgef18a NA coding downstream 12085 18466050 ~ 18479721 (+)
dapk3 dapk3,LOC102784251 coding downstream 42726 18496691 ~ 18505667 (+)
prkci prkci coding downstream 68004 18521969 ~ 18556360 (+)
nadkb LOC103353035,LOC102782138,LOC101483211,LOC102289018 coding downstream 155248 18609213 ~ 18625177 (+)
LOC120568684 NA coding downstream 226635 18680600 ~ 18682419 (+)
G115733 NA non-coding upstream 9015 18379112 ~ 18385969 (+)
G115723 NA non-coding upstream 97475 18296146 ~ 18297509 (+)
G115705 NA non-coding upstream 132323 18262396 ~ 18262661 (+)
G115690 NA non-coding upstream 160926 18233743 ~ 18234058 (+)
LOC120568296 NA non-coding upstream 161278 18232617 ~ 18233706 (+)
G115781 NA non-coding downstream 68 18454033 ~ 18455620 (+)
LOC120567854 NA non-coding downstream 4216 18458181 ~ 18465450 (+)
G115793 NA non-coding downstream 34566 18488531 ~ 18490186 (+)
G115826 sec62 non-coding downstream 178751 18632716 ~ 18646383 (+)
G115856 samd7 non-coding downstream 194809 18648774 ~ 18649804 (+)
G115729 NA other upstream 40640 18305149 ~ 18354344 (+)
LOC120567767 NA other upstream 365089 18027280 ~ 18029895 (+)
LOC120568596 LOC103479750,LOC106948690,LOC102229933,LOC103146349,LOC108232807,LOC105930991,LOC100691642,LOC103353958,LOC107383564 other upstream 911431 17406497 ~ 17483553 (+)
LOC120568363 ankrd12,LOC103396444,LOC102778611 other upstream 1782778 16610376 ~ 16612206 (+)
LOC120568419 LOC102779359 other upstream 1867302 16439025 ~ 16527682 (+)
skila skil,LOC102782637 other downstream 112668 18566633 ~ 18602263 (+)
LOC120568691 NA other downstream 206464 18660429 ~ 18674140 (+)
LOC120568911 NA other downstream 266400 18720365 ~ 18725447 (+)
LOC120568770 NA other downstream 563074 19017039 ~ 19052242 (+)
emilin2a NA other downstream 993046 19447011 ~ 19465381 (+)

Expression


Co-expression Network