bcl2b (bcl2)



Basic Information


Item Value
gene id bcl2b
gene name bcl2
gene type coding
species eurasian perch (Perca fluviatilis)
category of species economic fish

Chromosome Information


Item Value
chromosome id NC_053122.1
NCBI id CM020919.1
chromosome length 39550354
location 23441591 ~ 23467811 (+)
genome version GENO_Pfluv_1.0_2020_eurasian_perch_Genome

Sequence


>XM_039815258.1
GCCTACTGAAGAGGATATTAGGAGCAATCGTGGAAGAGGGCTCAGTCCGACCTTGTCTGGCTCACAGTCCCGCGCGTGGTTGTGCGTAAACGCTGCTAAAATAGTTGGCGGCGTTTAAAGCCCCTTCAGGCGCGTACAACTTTGGCCctcattcatgttttttttcgcAACACATTCACGTCTGGGTGTTGTGCACAGGACAACCTCTTCCGCATATTGGATTTCAATGCAAAGAGAAGGTCGCCAACGTCCATCTAAGGATTCGGGAAATGAAGACAGCTACTGACACGGACTCAgtattatttttacttttgaaaCGTTTGAAACGCAGTTTTGATTAAGGGATTTTCTTCAACTCGCGAAGCATTTGCTCCCTGTGTGGGATTACTCGTTGCATTGCTCTTATTTGAATGTAATTGAGTTTTGGATACGCCTGTGCTGTGCATTGTACAGTGCACAAATTCGATCACGATGTATTTAATTTAGGACAACCTCTTTCTATACAAAGTGCCAAATTAAGCCGGAATGGCGAACGAGTGTAATCGCAACATTGTGGAAAAGTATATCTGCCATAAACTCTCCAAACGGGGCTACGTGTTTGGGTTTGATGATGTCCGGGATGAAGATGCTGCTAATAATGGGTCAATAGTTGTCCCTCCACCGACTTTGGTTCGCCGGTGCCGTGAAGCCAGCACTGGGCCTGACAGCGAGAGCATCCCTCACCTCTGCAAACGGCTCCCCCAGTCTGACCCGACCGCCGCCATCCACAGAGTTCTCCGCGAGGCTGGAGACGAACTTGAGAGACTATACCAGCCGGACTTCACGGAGATGTCGCGGCAGCTGTATCTCACCTCCACCACGGCGCAACGGAGATTCGCCGAGGTGATCGACGAACTGTTCCGGGACGGGGTGAACTGGGGCCGGATAATCGCTTTCTTCGAGTTCGGGGGCACGGTGTGCGTGGAGTGCGCCGCCAAAGAGGAGATGACATCGCAGGTGGACAACATCGCCGAGTGGATGACGGAGTATCTAAATGGACCTCTAAACAGCTGGATACAAGATAACGGAGGATGGGCTGCCTTTGTGGAGCTGTATGACAGACAGAGGGACTCCCTCTTCAGCTGCTCCTGGCCCTCCATTAAGACGGTCTTTGGTCTAGCTGCACTCGGGGCAGCTAGCCTCACCTTCGGAGCATACCTGACACAGAAGTGAAAGAGCCCTCGTTCTACCAGCTTGACTTTattccttctcctccttcttctccttgTGCCTCTTCTTATTCCTTTTTATAGACGCCCCTGACCCCTCAGAGACAACCTTCAGACTCTTTTGAATCTGGCTCTCTTCAAAGCCCTCTCTCAGAAATCTCCCTCTTCCTCGCCCCTACATGTCAAAACAGACACAAATCAAAACAACTGAAGCAACCAGATGCACAGCCTATACAGAGCAAAGGATGTCTTGAAAAGAGGCAACTTAGATGTAATCACACTAATCTGCTGAGTAGCCTACAACTGAGAAATGAGGTGGCATCAGTGgcatgcattttttatttttttttgttctgcctGCTTCTGTACTAGTTATAGCATGAATGTTGAGTGTTTGTGTAGATGTTGTTGCATGTGTCAGAGCTCATGCAGGATCTCTCTTTGGAGGCCTTGGTGATGGGGGTGCAGGGACAACGATGCTCCAAACCGGAGAGGAAGCGGCCGCAGCCCTGCCCCTGCTTGTTAGGGTGAAGAACCCCGTTTTGAACTgtgttgccccccccccccctgcagcCGTCCTTCAAAGGACTTCCTCCACAGAACAGCTGCTCAGAATGTATAATGGAAACGGCACGGTTTGTGTCTACTGCTTTCACTCCTTAGACAGCTCCAGTGAACTTTGAACACACTGCACCATTATACTCTCCATGGTCCTTAATATGTAGAGGAAGGGCCAGCGGAAGACTGAGGTCTGCTGATATTTCTTTTGCAGAGTTCGAAAGCTCCTCGATTGAGATTTTGATGTTGGTTTTAATTTTTGCAGCATGCCAAACCCCAAATTGTGTGGTTTtaccacagaaaaaaaagaggagaatgGAGAATTTTTTGAAGGACTGAAAAGCATGCAGAAGAAGTCTGTTGTTGCATAAAACTCATATGATGATGAATATACTGAGAAAAATGTCACGCGCAGCACAAAACAGTAAGGTAGAAGCATCTTAAAAAGGAAGCATGAATGGACAGGATTTGAAATGTGCATTCCTCAAGCAAAGCGATGTGAACGAGACCACCCATCTGCTAAAATGACTCTACTTTAAAAGCACCATCACTGTTCACTGATTAGCACCAAGCAACccttaaaaacagttttgttttctattttctaCCACTGTTTCTACCAGCTTTCTTACTCTTAACTCAGTCCATTCGTTGTCAGATTGTTTGGGCTCACCCAGGTCTCAGAGCTGACCCTGTCAACATGTGTCCTCCAGCTGCTGAGGCCCCACAGTGACCTGGTACTTCTAGAATCCACTCTGACAAAGACGCTTGTTGATGTGGACTGAGAAAATCTCGCTTGGCCACAGATGACTGAGTGGAATACCACGGCAGCAGGGTTTCAGTTTAGGACTAAAGCCAGTGGGTCCCGTGTGCTGGAACCTGAGATGTCCCCTCTCTCCGGTCTGCAAATGCGTTCAGTCATTGATTTGTTTTATTGATGTTTGTCTTGTGTTACAGTCTGACAGAAAATTTGGAAATGCTCACAGGCTTCAAAAGATTTTGTTGTAGCCTGCACAACTTTACTTGGTTAtggaaaagtgatttttttttgtcattacaaATCTTCAACTTCTTTATTGCATGGATGAAAGATACTGTCTTCACACGAGAAATATGTGTAACCATATTTATAACAGAATAGGGTAGAAGATAACGAATAACAGCAAAGGAGTTGCATTTTTCTATTTATTGAGAGGTACCAgatcacagattttttttaacagtagctactttgatgaaaaataaattgttttcaccttttttCTGTTCTATTGAATCACACTGTAACTACATTTTTTTCCTGGCTGCTATTATAATGAGaaagatgttttaaaaaaaaaaaaaagtgaatttctGTGTTGTATTACTATTGGCTTAAGGCTGCTATACTGTcgatttaacttttaattaacAGCttaaactgccacagatttacAGTATAGTTCTTGAGAGCTGGAAACCAAAGTTAACTTGTATTaatctttaatttaaaaaaacaaacaaaaaaagtagcTTAAGGAGGATACACGTTGCTTCACTTCACTGAGTCTATTCAGTGAGGTTTTATGATCTCTCTGGGTTTGTCTAGTGTTACTGTACTATATCAGCTTAACTTTTGTCAGCTTTGTGCTCCAATGATGACTCAGTGCTTATCTGTAAAATGTTGACCTGCCAGAGTTAAACCTTGTCTCAGTTGTCCCACTCTCATTACAGCAACTCACAGTCGTGTGATATTCCTAGtgatgtgtgtgtaagagagaatCAGAAGGCTATTTATGAGCAGGAGTAGGAACAGTTCAACCGcaatatactgtaattttatATTCTCTGTGCATAATATATGAATGTAGACGCCATGGTTGCTACTGTTTCATGTCTATAATCACAAACCTGTAGCACTTAAAAAAGTgaattgtgtttctgttgtttacTGCTATATCCACAATAAGCTAGTGGGATCATATTGTTCCTAATAAACCAGATTTCTCAAGCAGCTGCAGTCCAAGTTCACGTTGcgtctgctttaaaaaaaaatgtttttatcgaTTCTCAGCTTTGTCTCCGTGCATATCCgcaagacagaaagaaaataagagAAATTGTCAGTGAAGAGCAGTGTATCAACAGTGCTGTTTTGATGATCTGTGATCTATTCACAGCTGTGAATTGTATATGTAATCTTGGTTGTGTCAACGTGAGCGTCCTTGTGAAGGACTGTGaaagcacagcagcagcaccccATCAGACATCAAAGCTGTCCCCAAACACTGCACTTGTCAGCCTCCCTCTTCTGCTCCATGTGCTGTTAAACATGAGTGCAAAAACCCAAAATGCCCTGaggctagttttttttttttttactgttctgATCACACTTGTCTTCAAAGGCCACGGCACTCTTGCTGCTCGGTGGAATTTGTGAAAAGCATGATGTAGTAAAACTAATGTTGAAAGAGTTGAGTGGGTATGGTAAAATGAAGGGAGTGAAAgaaagtggtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgcgcacacataCATCCCTGAGGAGACCAACAGGAAAGTTCATTTGGGCTGGAGCCCCACGCAAAACCTCCTCTCGCTCCCTCACTCGCCATGCATATAAAATGCAGGACACGCTCTGAAGAGGAATGTTAAATCAAGCCAGAGACTTTCAAAAGAGAGTCCAGTGTGAGTGTGgatggtgaatgtgtgtgtgtgtgtgtaaagaaagAGATGGGCAGTAAGAAgaggaaagggggaggggggggcggtGAGTGAAGCCCTCCTGCCTCTTCTGCTTTAGGGCTACACGGTGTAGAGGAGGCTTCCCCAGCACTGGATATCACAGGGGAGATTGGGAGATCAAAGCAGATTGTCTGGAGTAAGTCTGGTCCAGTTATACCCCTCATTTGGAAGTCCATCAGATCCACTCACGGCACCTTTGCCTCATTTAGAGGCAGCCTTTGCTGCATTAAAAACTTCCTTCTGAAATCTAGCAATTTCCTTAAAAAGAGATCAAAAAAAGCACCCCTCGCAAATCATTCATCTCTCATTGGAATGCAAATATTCAATGAGAAAGAGTTACTTATTACACCAACTGTAgaagcagattttttttaagccttgaAGTCCTGCCTGAAATGTGTGCTGCAGTGTCACCTTGTGGCTGCTTCACAAACAATCCAGCAGGGTTTAAAACATCAGGCAATCACAGTGCCAAGAGTCTGCACATTTCTACCTCATCTACAGGAAATGACAGCTGATTTCACTGAGCAGATCATCTTCAAATATGGAGAATGAACCATCAGCTGCTGCAGCATTCAGCTGAAATAAAAACCAGCCTTTTCTCAGCACTCTCTGGCACATGGTTGCCTATCCCTGCTCTAAAATATCCTCAGGGCACCATGCCATGAAGAGAAAAAGGCTCCAGGCGGAAGGCTCAACTGCTTACAGCTTCGGTGATGACTGTTCAAGCCGTCTGTGGTTAGTGATAGTCTTCTTAGAAATGTCTAATGAAAGAAAAGCATCTGAATCTCACAGAATATGGTAATCAGAAGGAAAGAAGACGTGGTGTAACTTCCAACTTCAAATCATGTCTGTGATAACCCATACAGACCATTTGTTCAAAGCTTTAAAAAGTAATGTTAAACTATTTGTTTGAATACTAAGTGATAGTACTGAAGGTTACTGTAGTGCTGCACATACCACAACACTGCTTTGTAATAATTTGTTTTGTGGTGTTGCTTTTTCAGGGTTTTTGCTGATATGAAAATTAGGAAACTATTGCAACACTGTTATTTACTGTCGTCCATCATTAAAGAACAGTTGTACGTGT

Function


symbol description
bcl2 Enables several functions, including BH3 domain binding activity; enzyme binding activity; and protein heterodimerization activity. Involved in several processes, including B cell receptor signaling pathway; negative regulation of apoptotic process; and positive regulation of B cell proliferation. Acts upstream of or within several processes, including B cell proliferation; apoptotic signaling pathway; and negative regulation of apoptotic process. Located in endoplasmic reticulum; mitochondrial outer membrane; and nucleus. Part of pore complex. Implicated in several diseases, including carcinoma (multiple); hematologic cancer (multiple); intracranial aneurysm; prostate cancer; and urinary bladder cancer. Biomarker of several diseases, including cervix uteri carcinoma in situ; ductal carcinoma in situ; gastrointestinal system cancer (multiple); hematologic cancer (multiple); and urinary system cancer (multiple).

NR:

description
PREDICTED: apoptosis regulator Bcl-2

GO: NA

KEGG:

id description
K02161 BCL2; apoptosis regulator Bcl-2

RNA


RNA id representative length rna type GC content exon number start site end site
XM_039815258.1 True 5603 mRNA 0.44 2 23441591 23467811

Neighbor


gene id symbol gene type direction distance location
vps4b vps4b coding upstream 8217 23422716 ~ 23433374 (+)
LOC120569134 NA coding upstream 97696 23325302 ~ 23343895 (+)
LOC120568373 znf521 coding upstream 138802 23212498 ~ 23302789 (+)
ss18 ss18 coding upstream 252020 23177741 ~ 23189571 (+)
LOC120568942 kctd1,LOC103479566,LOC103373355,LOC106534090,LOC108239680 coding upstream 294174 23134256 ~ 23147417 (+)
glula LOC103366706,LOC100534445,LOC108239682 coding downstream 348229 23816040 ~ 23820441 (+)
trnaw-cca_13 NA coding downstream 400443 23868254 ~ 23868325 (+)
gigyf2 gigyf2 coding downstream 402240 23870051 ~ 23890968 (+)
snorc NA coding downstream 423333 23891144 ~ 23896911 (+)
LOC120567818 gpr55,LOC103396173,LOC103366713 coding downstream 431397 23899208 ~ 23905529 (+)
G117190 NA non-coding upstream 63075 23377133 ~ 23378516 (+)
G117187 NA non-coding upstream 67392 23373710 ~ 23374199 (+)
G117128 NA non-coding upstream 523485 22917876 ~ 22918106 (+)
G117082 dsp non-coding upstream 687101 22752252 ~ 22754490 (+)
G117077 NA non-coding upstream 693859 22747120 ~ 22747732 (+)
G117220 NA non-coding downstream 809 23468620 ~ 23519769 (+)
G117221 LOC101467149 non-coding downstream 4736 23472547 ~ 23473684 (+)
G117228 NA non-coding downstream 25295 23493106 ~ 23566317 (+)
G117297 LOC104918287,LOC103479586,LOC107686770,LOC108443834,LOC107083372,LOC106929027,LOC108239658 non-coding downstream 274673 23742484 ~ 23745977 (+)
G117315 NA non-coding downstream 380876 23848687 ~ 23848946 (+)
kdsr kdsr,LOC102792240 other upstream 748 23433625 ~ 23440843 (+)
LOC120568311 LOC103368946,LOC103142996,LOC106925933,LOC104929332 other upstream 760298 22641510 ~ 22681293 (+)
LOC120567968 NA other upstream 821460 22608049 ~ 22620131 (+)
LOC120568354 NA other upstream 1544200 21870953 ~ 21897391 (+)
LOC120568904 crhr2,LOC101476678,LOC102776588 other upstream 2526269 20882617 ~ 20915322 (+)
LOC120567964 dpp6,LOC100710983 other downstream 124921 23592732 ~ 23685804 (+)
G117319 LOC101487892,LOC104941256 other downstream 383068 23850879 ~ 23855157 (+)
G117353 LOC103366712 other downstream 438059 23905870 ~ 23908401 (+)
hes6 LOC104918282,LOC104941260,LOC103366710 other downstream 444853 23912664 ~ 23914498 (+)
G117400 LOC104965054 other downstream 554630 24022441 ~ 24023659 (+)

Expression



Co-expression Network