XLOC_004740 (glud1b)


Basic Information

Item Value
gene id XLOC_004740
gene name glud1b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007123.7
NCBI id CM002896.2
chromosome length 49182954
location 25845494 ~ 25881944 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00009386
GCCTAGCTCGGCTCCTCTGAACACGCCGCTGCCTTTTAAAGCGTGAATCGGCATGAGCGCTGACACTTTGACACTGAACGAGGCAGGCTCAGGAGCAACTGTCGTCTCGTTCATTTACCCCCCTTCTCGTTTCCTTTTTCCATCTCGTCGATAACCCAGCATCATTTCATCTCTTCTTTCTCCACAGTACCGTAACTTTCAAAGCCCCTTGTCGCCATGTACCGGTATTTCGGGGAGCTGCTGACTCGCGGAGCGGGAAGCGCTCTGGCCTCGGGATGCGTCGAGTCCGCTCTGCCGGCTTCCTCGTCTCTGCTGCGGGTGCGCCACTACAGCGATGCCGCTGACAAGGAGGACGACCCCAACTTCTTCAGGATGGTGGAGGGCTTCTTTGACCGCGGCGCTACTATTGTCGAAAACAAACTGGTGGAGGACCTGAAGACCCGGGAGACGCCGGAGCAGAAGAGGAGCCGTGTGCGGGGAATCCTCAAGATCATCAAGCCCTGCAACCACGTCCTGAGCGTGTCCTTTCCCATCAAGAGAGACAACGGAGAATGGGAGGTTATCGAGGGTTACCGGGCACAACACAGCCAGCACAGAACACCCTGCAAGGGGGGTATCCGATACAGCATGGATGTGTCTGTGGATGAGGTTAAAGCTTTGGCTTCCTTGATGACTTACAAGTGTGCTGTTGTAGATGTGCCATTTGGTGGAGCTAAAGCTGGAGTCAAAATCAACCCCAGGAATTACTCTGATAATGAGTTGGAGAAGATCACAAGAAGGTTCACAATTGAACTGGCCAAAAAGGGATTCATTGgaCCTGGCATTGATGTACCAGCCCCTGACATGAGCACTGGTGAGAGGGAGATGTCCTGGATTGCTGACACCTATGCTAACACTATTGCCCATACAGATATCAATGCCCATGCCTGTGTGACGGGAAAACCCATTAGCCAGGGTGGCATCCACGGCAGAATCTCAGCCACAGGTCGTGGAGTCTTCCACGGCATTGAGAACTTCATCAACGAAGCCTCATACATGAGCAAACTTGGCCTGACTCCTGGATTTGCTGACAAAACCTTTATTATTCAGGGCTTTGGTAATGTGGGTCTGCATTCCATGCGTTATCTTCACCGTTATGGAGCCAAGTGTGTAGGAATTGCTGAAATCGATGGCAGCATCTGGAACCCCAACGGCATGGACCCCAAAGAGCTGGAAGACTACAAACTGCAACATGGCACCATTGTGGGCTTCCCCAACTCTCAGCCATATGAAGGAAACATTCTGGAAGCTCAGTGTGATATTCTCATCCCTGCAGCTGGAGAGAAACAGCTGACCAGGAAAAATGCACACAATATCAAAGCTAAGATTATTGCTGAAGGTGCTAATGGTCCCACAACACCCGATGCTGACAAAATCTTCATTGAGAGGAACGTCATGGTCATTCCAGACATGTACCTGAATGCCGGAGGTGTCACAGTCTCTTACTTTGAGTGGCTGAAGAACCTGAACCACGTCAGCTATGGTCGCCTGACCTTCAAGTATGAGAGGGACTCCAACTACCACCTGCTGATGTCTGTGCAAGAAAGTCTTGAAAGGAAGTTTGGAAAGCAGGGTGGCCCCATCCCTATTGTACCCACTGCTGATTTCCAGGCTCGTGTAGCTGGAGCTTCTGAGAAGGACATTGTTCACTCTGGTCTTGCTTACACCATGGAGAGGTCGGCCAGGCAAATTATGCGCACGGCCAACAAGTACAACCTGGGCTTGGATCTGAGAACAGCGGCTTACGTCAACGCCATTGAGAAAGTCTTCAAGGTGTACAACGAGGCTGGTCTGACCTTTACATAAATCTCCTTTcacaaaaaacaagacaaaaacgtTCATCAACCTCTCAATTTCCCCGTTTTAACATATCAGAGTTTACATCATCTTCTCTATCATAACCCCGTCGTATCCCAGAAGCTCCGTCCTAATGAGAAACTCTAGCATGGTTTATACGGTTTCACTGCTTTGCTGTAAGTGCAAACTGGAGCCCATATTCAGGTTTCTCAAGTAATTCTTGTTGTAACTTGTTTATTTAGCTTCTGGTTTTTGTATTGATCTGTGGTAAACTGTTGTGGTCCTCTTCAAATGCAgctgttttaaatgtatgttgATTTAATCAGTTGAGTTGGTGCGTTTTTGTCCTCTgtcatgttttatttactttattcctACTGTTTGTCGTCACAGACCATTTTATCGATGGTCATTGCTAATGAAGGAATGAAGAGCGTTAAAAATGCCTTACAGTTGCGAGCAGGAGTTTTATACTCTCACTGTTAGTTCATATTAAAGGGAAGCCCAGCCATTTTGTTTGCCTCATCTCACTGTTTTTAACCCAGAGACGTAATGGAGTACTAGCCGGAAATGTGCTGTACAATTTAGATACagactttattttgtattcagaGCAGTTTGTATCCCTTGACGTTTAGAGATCTGTTTGTTGTTAGTGTGCGGCTAATGCTAATGCTACAGCTAGAGAAGCCAGGCCACATGTGCTTACATCAAAAGCTGGAAGCTGCTCACCAAACGTATCTGCACCCACGTCTGGAACTGTGTTTTGGGAGTTTATATTGGCTTTTTTTTGTTGAGAATAAATTCCAGTTCTCATAATTTA

Function

symbol description
glud1b Predicted to enable glutamate dehydrogenase (NAD+) activity. Predicted to be involved in glutamate catabolic process. Predicted to act upstream of or within cellular amino acid metabolic process. Predicted to be active in mitochondrion. Is expressed in several structures, including blastomere; digestive system; fin; mesoderm; and tail bud. Human ortholog(s) of this gene implicated in familial hyperinsulinemic hypoglycemia 6; hyperinsulinism; hypoglycemia; and late onset Parkinson's disease. Orthologous to several human genes including GLUD1 (glutamate dehydrogenase 1).

GO:

id name namespace
GO:0055114 oxidation-reduction process biological_process
GO:0006520 cellular amino acid metabolic process biological_process
GO:0006538 glutamate catabolic process biological_process
GO:0005739 mitochondrion cellular_component
GO:0016491 oxidoreductase activity molecular_function
GO:0004352 glutamate dehydrogenase (NAD+) activity molecular_function
GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-030828-1 Predicted to enable glutamate dehydrogenase (NAD+) activity. Predicted to be involved in glutamate catabolic process. Predicted to act upstream of or within cellular amino acid metabolic process. Predicted to be active in mitochondrion. Is expressed in several structures, including blastomere; digestive system; fin; mesoderm; and tail bud. Human ortholog(s) of this gene implicated in familial hyperinsulinemic hypoglycemia 6; hyperinsulinism; hypoglycemia; and late onset Parkinson's disease. Orthologous to several human genes including GLUD1 (glutamate dehydrogenase 1).

Ensembl:

ensembl_id ENSDARG00000101074

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00009386 True 2659 mRNA 0.47 13 25845494 25881944

Neighbor

gene id symbol gene type direction distance location
XLOC_004739 epas1a coding upstream 15226 25775734 ~ 25830268 (+)
XLOC_004737 prkcea coding upstream 75262 25640480 ~ 25770232 (+)
XLOC_004738 CR932018.1 coding upstream 197251 25648127 ~ 25648243 (+)
XLOC_004736 six3b coding upstream 242153 25600685 ~ 25603341 (+)
XLOC_004735 NA coding upstream 341114 25502406 ~ 25504380 (+)
XLOC_004741 mmrn2b coding downstream 63616 25945560 ~ 25948479 (+)
XLOC_004742 itgb3b coding downstream 552534 26434478 ~ 26461744 (+)
XLOC_004743 ndel1a coding downstream 585903 26467847 ~ 26487363 (+)
XLOC_004744 NA coding downstream 607409 26489353 ~ 26491973 (+)
XLOC_004745 armc7 coding downstream 609693 26491637 ~ 26494851 (+)
XLOC_004733 CR932077.1 non-coding upstream 415123 25312018 ~ 25430371 (+)
XLOC_004731 CR848736.1 non-coding upstream 630767 25201543 ~ 25214727 (+)
XLOC_004728 CR385067.1 non-coding upstream 770374 25073305 ~ 25075120 (+)
XLOC_004748 NA non-coding downstream 707700 26589644 ~ 26593298 (+)
XLOC_004751 NA non-coding downstream 809875 26691819 ~ 26692051 (+)
XLOC_004752 NA non-coding downstream 855487 26737431 ~ 26834192 (+)
XLOC_004754 BX469896.1 non-coding downstream 1012377 26894321 ~ 26896616 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
bowfin (Amia calva) AMCG00003174 gdh01,gdh3.2,glud1 coding CM030139.1 CM030139.1 13848510 ~ 13871340 (-)