XLOC_004742 (itgb3b)


Basic Information

Item Value
gene id XLOC_004742
gene name itgb3b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007123.7
NCBI id CM002896.2
chromosome length 49182954
location 26434478 ~ 26461744 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00009388
CTACAGAGGTTCCTGTAAATGCTTCAGGCTCCATCACAGTCCAATCTCTCAATAATCTCCATCCTGGCCCACAATTTTCTACAGTATCAAGGCCATCTGGTTGCAGGTATAGGCAACAGTTCCAGAACCCGCGGCAAATGTTCGTGAGTCGATCCCTCATATGCCCCCTCCCTCGAAAACAAGCTTTTACCACAATTTACTCTATATTTGGTGTTGGTCTGATGTCTGTGCTGGACCGTAAAGGAAAGGAAGAGGAGGGCGCAGACTGCACAAACCACCGGTGAAGTAGAGGAGAACAGCGATAACAACGATGGAGGAAACTTCAGCCAAACTCTTCAGCTTATGGATTTACTGTGTAATTATTTTCCTATCTGATGTTGGACTAGGTTCTAACGTCTGTACTTCTCGAGGAGCCAGTACATGTCAGCAGTGCC
>TCONS_00009389
GTTAACATAATCTTCCTCTATTAATAACAAGCGGTTTTGATCACGGTGATCTTTCGCAGGTATAGGCAACAGTTCCAGAACCCGCGGCAAATGTTCGTGAGTCGATCCCTCATATGCCCCCTCCCTCGAAAACAAGCTTTTACCACAATTTACTCTATATTTGGTGTTGGTCTGATGTCTGTGCTGGACCGTAAAGGAAAGGAAGAGGAGGGCGCAGACTGCACAAACCACCGGTGAAGTAGAGGAGAACAGCGATAACAACGATGGAGGAAACTTCAGCCAAACTCTTCAGCTTATGGATTTACTGTGTAATTATTTTCCTATCTGATGTTGGACTAGGTTCTAACGTCTGTACTTCTCGAGGAGCCAGTACATGTCAGCAGTGCCTGGCTGTGCATCCAACCTGTGCCTGGTGCTTTCAAGAGGATTTTGGACAAGATGTTCCTGGCTCTTCCCGATGTGACCTGAAAAGGAACCTTGTAGAAGCAGGATGCAACAAGGGAGCTCTGGAGTATCCAACCAGCAAAATGCACGTAAAAGAGAATGAAGATCTCAGTGACAAGGCCTCAGGATCCACCACTGACGTCACCCAGATCCAACCTCAAAGCATACACATCTCTCTGAGACCCGATGATTCGCAGGTTTTCAAGCTGAAAGTCCGACAGGTAGAGGACTACCCTGTGGATTTGTACTATCTGATGGACCTGTCCTACTCCATGAATGACGACTTGTCTCAGTTGAGACGGCTGGGGCGAGGCCTGGCTGAAGAGATGAGCAAAACCACTAGTAATCTGCGCATGGGCTTTGGGGCTTTTGTGGATAAACCTGTGTCCCCGTACATGTACATCTCCCCTGAGGAAGCCGTGTTAAATCCCTGCTACTCAATCCCGTACAAATGCCAGCCTCAGTTTGGCTACAGACACGTTCTGTCTCTGACGGAGGAGGTGAACCGCTTTACAGAAGAAGTGAAGAAACAGAAGGTGTCCCGAAACAGGGACGCGCCAGAGGGAGGCTTTGACGCCATCATACAAGCAGCCGTGTGCAAGGACAAAATTGGTTGGAGGCCAGGTGCATCCCACTTGCTGGTTTTCACTACAGATGCCAAAACACATGTGGCACTGGATGGGCGTATGGCAGGAATTGTGCGACCCAATGATGGCCAATGCTATGTGGGCAGGGACAACATCTACAATATGTCCACAACTATGGACTACCCATCCCTGGCACTAATCACAGAGAAAATGTCTGAGAACAATATAAATCTGATCTTTGCTGTAACTAGCCATGTGGAATCACTCTATAAGAACTACAGTGAGTTGATCCCTGGCACTGCAGTGGGTACGCTGTCCGAGGACTCTCATAACGTCATCCAGCTGATCCAGGATGCGTATGCTAAACTGCGCTCTAAGGTAGAGCTGGAGCTCTTGAACGTCCCGGAAGAGCTCAGTCTAACATTTAATGCCACATGTCTCAACGGAGAGGTCATTCCTGGGCTGAGATCCTGCTCAGGCCTCAAAAGAGGAGATACCGTGTCCTTCAGTGTTGAAGCCCGAGCCAGAGGCTGTCCGAAGGAGAAGCGCAAAACCTTCACTATAAAACCAGTGGGCTTCAAAGACACCTTGCAGATCACAGTCAACTTTGAATGTGAGTGTAAATGCCAAGCAAAGGCTGAGCTTGAGAGTCCCGTCTGCCACCACGGCAATGGCACCTATGAGTGTGGCATCTGCCTGTGTCACCCGGGGCGGCTGGGTCCCCGCTGCGAATGTGCAGAGGGCGACTACAGCCCAACAGAACAGGACGCCTGCAGTGGGCCAGACAAGGTGATCTGCAGCGGCCGGGGAGACTGTGTGTGCGGACAGTGCGTCTGTCACAATAATGACTTCGGCAAAGTATGGGGGAAGAGATGCGAGTGTGATGATTTCAGCTGCCTGCGCTATAAAGGAGAGCTCTGCTCAGGTCATGGCACTTGTTACTGTGGGTTTTGTCAGTGTGATCCGGACTGGAAAGGGGAAAACTGCAACTGTTCCACTCGAACAGACACCTGTATGTCCAGCTTGGGTCTGCTGTGCAGCGGTcggggtcagtgtgtgtgtggcagctgtGAATGTACTCAACCAGGTGCTTATGGATCTACCTGCGACAAATGTCCCACCTGCCCTGACGCCTGCACACTGAAGAAGGAGTGTGTAGAGTGTAAGCACTTCAAGAGAGGGAAACTCTTCGATGATGATTCCTGCACTCGCATCTGCAGAGATGAAATCAGACTAGTGGATGATCTTGTGTTCCATGATAAGAATGCAGTGAATTGCACCTATAAGGATGAGGACGACTGTGTGCAAAGGTTTCAGTACTACGAGGACAACAGTGGCAAATCCATCTTGTCTCTGGTCAAAGAGCCAGATTGCCCTAAAGGCCCCGATATCTTGGTGGTGCTGCTGTCAGTAGCTGGTGCCATCTTATTCTTGGGTCTTGCCGCCTTGCTTATCTGGAAACTATTAATAACCATTCATGATCGGCGTGAATTTGCGAAGTTTGAGGAGGAGCGGGCACGAGCTAAGTGGGAAACGGGTCACAATCCCCTTTATAAAGGCGCCACGTCGACATTCACAAACATCACATATCGAGGCAAAGACTGACCGCAGAGAAAGGACTGGACAGCGCTAAAAAGACAGTGttctttttaaaagtttaaacgtTAAAACTTTCTTAAAGAATTATGCAAACATGAAAGAGTTGTAGATATTTTGTTGCTGTACATATGTAAAGTCAAATATGGCATCTTCatgtggcaagccgttttaacatttaatctataaactgttctaatatttattttcatgcaatACCCAGTTTTtgatattagtattttttatcttattcattatgtattatattctagttcttatttattagatactactaCTTATTAAATGGACACTATTAATAGCTATTAAAAA

Function

symbol description
itgb3b Predicted to enable fibronectin binding activity and integrin binding activity. Predicted to contribute to fibrinogen binding activity. Predicted to be involved in several processes, including cell adhesion mediated by integrin; cell-matrix adhesion; and integrin-mediated signaling pathway. Predicted to act upstream of or within platelet aggregation. Part of integrin complex. Is expressed in brain; cardiovascular system; dental epithelium; digestive system; and pectoral fin fold. Human ortholog(s) of this gene implicated in several diseases, including acute myeloid leukemia; autoimmune thrombocytopenic purpura; blood platelet disease (multiple); end stage renal disease; and non-arteritic anterior ischemic optic neuropathy. Orthologous to human ITGB3 (integrin subunit beta 3).

GO:

id name namespace
GO:0070527 platelet aggregation biological_process
GO:0007229 integrin-mediated signaling pathway biological_process
GO:0016477 cell migration biological_process
GO:0007155 cell adhesion biological_process
GO:0007160 cell-matrix adhesion biological_process
GO:0033627 cell adhesion mediated by integrin biological_process
GO:0005925 focal adhesion cellular_component
GO:0008305 integrin complex cellular_component
GO:0009986 cell surface cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0005515 protein binding molecular_function
GO:0070051 fibrinogen binding molecular_function
GO:0005178 integrin binding molecular_function
GO:0001968 fibronectin binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-071207-2 Predicted to enable fibronectin binding activity and integrin binding activity. Predicted to contribute to fibrinogen binding activity. Predicted to be involved in several processes, including cell adhesion mediated by integrin; cell-matrix adhesion; and integrin-mediated signaling pathway. Predicted to act upstream of or within platelet aggregation. Part of integrin complex. Is expressed in brain; cardiovascular system; dental epithelium; digestive system; and pectoral fin fold. Human ortholog(s) of this gene implicated in several diseases, including acute myeloid leukemia; autoimmune thrombocytopenic purpura; blood platelet disease (multiple); end stage renal disease; and non-arteritic anterior ischemic optic neuropathy. Orthologous to human ITGB3 (integrin subunit beta 3).

Ensembl:

ensembl_id ENSDARG00000045070

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00009388 False 434 mRNA 0.47 3 26434478 26437252
TCONS_00009389 True 2957 mRNA 0.48 15 26435918 26461744

Neighbor

gene id symbol gene type direction distance location
XLOC_004741 mmrn2b coding upstream 485999 25945560 ~ 25948479 (+)
XLOC_004740 glud1b coding upstream 552534 25845494 ~ 25881944 (+)
XLOC_004739 epas1a coding upstream 604210 25775734 ~ 25830268 (+)
XLOC_004737 prkcea coding upstream 664246 25640480 ~ 25770232 (+)
XLOC_004738 CR932018.1 coding upstream 786235 25648127 ~ 25648243 (+)
XLOC_004743 ndel1a coding downstream 6103 26467847 ~ 26487363 (+)
XLOC_004744 NA coding downstream 27609 26489353 ~ 26491973 (+)
XLOC_004745 armc7 coding downstream 29893 26491637 ~ 26494851 (+)
XLOC_004746 chad coding downstream 50825 26512569 ~ 26525699 (+)
XLOC_004747 faap100 coding downstream 77117 26538861 ~ 26547248 (+)
XLOC_004735 NA non-coding upstream 930098 25502406 ~ 25504380 (+)
XLOC_004733 CR932077.1 non-coding upstream 1004107 25312018 ~ 25430371 (+)
XLOC_004731 CR848736.1 non-coding upstream 1219751 25201543 ~ 25214727 (+)
XLOC_004728 CR385067.1 non-coding upstream 1359358 25073305 ~ 25075120 (+)
XLOC_004748 NA non-coding downstream 127900 26589644 ~ 26593298 (+)
XLOC_004751 NA non-coding downstream 230075 26691819 ~ 26692051 (+)
XLOC_004752 NA non-coding downstream 275687 26737431 ~ 26834192 (+)
XLOC_004754 BX469896.1 non-coding downstream 432577 26894321 ~ 26896616 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000063_05922194_05935361 ITGB3B, ITGB3 coding CI01000063 null 5922194 ~ 5936249 (+)