sirt2 (sirt2)


Basic Information

Item Value
gene id sirt2
gene name sirt2
gene type coding
species eurasian perch (Perca fluviatilis)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_053113.1
NCBI id CM020910.1
chromosome length 48524041
location 19525721 ~ 19532651 (-)
genome version GENO_Pfluv_1.0_2020_eurasian_perch_Genome

Sequence

>XM_039780820.1
CACGGACCGTGTTTCCGAcggacaacaacaaaacggtCCAGCTGAGTGccaatatatatgtcaatggtgccAACTGTGTAGTGAATATTGGTCGTAACTTAATAAAGTTGGggatttaaatacattttctttcggACCCTTGTGGTTGAAGGGTCTCAGTAGACGGTTAAATGTCTGATGCATCAGAACTtcctaaaaaagaagaaaaggaggaggaggttacACCTGAACCAGAGGAGGAATCGGACGACAGCAGTGGGGAAGAGGCTACAGGAGACACAGAGATGGACTTCCTGCGGAACCTCTTCTCCAGCACCCTTGGTCTCGGCTCGGCAGACAAAGTTCTGGATGAGCTGACTCTGGACGCAGTGGCACGATACATAAAGAGCGGAAAATGTAAAAACATCATCTGCATGGTTGGAGCAGGAATATCCACATCTGCTGGGATCCCTGATTTCCGTTCACCAGGAACTGGCCTGTATGCAAACCTGCAAAAATATGATCTGCCTTACCCAGAGGCCATCTTCCAGATAGATTACTTTAAGAAACATCCAGAACCTTTCTTCGCCTTGGCCAAGGAGCTTTACCCAGGACAGTTTAAGCCGACAATCTGTCACTACTTCATGAAGCTGCTGAAGGACAAGGGACACCTGAGACGCTGCTACACACAGAACATTGACACCCTGGAGCGTGTGGCCGGGCTCGAGGGAGAGGATCTAATTGAAGCTCATGGAACGTTCTACACGTCTCACTGTGTCAGCTTCTGTTGCCGCAAGGAGTATAACCTGGACTGGATGAAAGATAAAATATTTTCTGATGACATTCCCCGATGTGACAAGTGCAAAAGTTTGGTGAAGCCAGATATCGTTTTCTTTGGAGAGAATCTACCTGTCCGGTTCTTCACTTCAATGAAGATGGACTTTCCCTGCTGCGATCTTCTCATCGTCATGGGGACGTCCCTGCAGGTCCAACCGTTTGCAGGTCTAGTCGGCAGGGTTTCAAAAAGTTGCCCCAGACTGCTTATTAATATGGAGAAGGCAGGGCAGGCTGATCCTCTGTTTGGGTTGTTGGGTTTTGGAGGAGGAATGGACTTTGACTCAGACAAGGCATACAGAGATGTAGCTCACATCAGTACATGTGATGAGGGCTGTTTGGCTCTAGCTGAGCTGTTGGGATGGAAGGAGGAGCTTGAAGAGTTGGTGAAGCAGGAGCATGCCAGGATTGACAGTCAGGACAAGAAAGAGAAGGCCAGTGGGAGCAAAGGAGCAGCAGCCAAGGCCAGCTCTGCATCAGTAGCACCAGAGCCAGAAAAGGAAGAGTAACTTATTAAAAAGCTCCTTTTCTAAAGAAACGCTAATGTAGTGATGTTATTGTTTGGAGTTGGCCCTTAAAGGGAGATGATGATACCAGGGTTTTTGCTTGGAAGTGAAGCTTCGACGGCTGCGGACATTTAATTCTCCTAAACAATCTCACAGGTTATGCTTCTGCTCATTTGCACTTTACTGATATTAATCTACTTTGctaatttgttttttcattaGCTTACATCTTTCTCAGCTGTATATTTATTTCTGAGGAAGTTAACTGGGCAGAGTTCTTCAAGGATGTTTACAGATCTCACAGAGCTTGGGAGGTGGTAAATATCTCTTAAACCCCGGCAGTGTGATTATGAGTTTGCTGAATTATAGAACAAGCTACTATATTGTCTCCAAACCGAATGATGAACACATCTGATTGTGTGATTTGGGCCAAGCCACTTCAACTCTCTTCACTTCTTTGAGTTGTTGATTTCAGTTTAAGCTTCCTCAAAAGATAACCAGGCTATTGTATATTGCCCCCCAAGCCGAAAtctgttggtctgattggtcaTTGACCTCTTCAAGGTATCACATTTAGCACAAATTGAATTTCCTGATAGGAGAGCTAAGGTAGTTGTTAAATGTAACAGTAGGATAGTTTGTTAATTTgaacttttaaaacatttaaaattaacACCGTTTTTCACGTTAACCTTCTGCTCCTGTTGGCTTTTAACGGTGTTTATGAGGCAAGTTGTATTTTATTAATCTTATGGAACAACAAACTGTACATGGTGCACAACATAACAGTAACTTTGCACACTCCACAGGCAGGACCATAGTTGATTTTGCTGTTTAATTCATTTTGGATAGTCAAAGTGCTGAAGAAACACAAGAAGGTTAAACTGACAAGAATTCTAAAATAAGGTGTAATTCGGTTCAAGAAGTAGTTTTTAATAGGATACTTTTGGGTTATCTAAAATAGCATGAATTGTTGCATCATGAAATACAGGGGGTGGACACGGTTACATTATCATCTATACCAAATAATGGAAACCAATACAAAAATTCTGCAATAAATTTGACCTTTGTGAAGCTGA
>XM_039780828.1
CACGGACCGTGTTTCCGAcggacaacaacaaaacggtCCAGCTGAGTGccaatatatatgtcaatggtgccAACTGTGTAGTGAATATTGGTCGTAACTTAATAAAGTTGGggatttaaatacattttctttcggACCCTTGTGGTTGAAGGGTCTCAGTAGACGGTTAAATGTCTGATGCATCAGGAGGAATCGGACGACAGCAGTGGGGAAGAGGCTACAGGAGACACAGAGATGGACTTCCTGCGGAACCTCTTCTCCAGCACCCTTGGTCTCGGCTCGGCAGACAAAGTTCTGGATGAGCTGACTCTGGACGCAGTGGCACGATACATAAAGAGCGGAAAATGTAAAAACATCATCTGCATGGTTGGAGCAGGAATATCCACATCTGCTGGGATCCCTGATTTCCGTTCACCAGGAACTGGCCTGTATGCAAACCTGCAAAAATATGATCTGCCTTACCCAGAGGCCATCTTCCAGATAGATTACTTTAAGAAACATCCAGAACCTTTCTTCGCCTTGGCCAAGGAGCTTTACCCAGGACAGTTTAAGCCGACAATCTGTCACTACTTCATGAAGCTGCTGAAGGACAAGGGACACCTGAGACGCTGCTACACACAGAACATTGACACCCTGGAGCGTGTGGCCGGGCTCGAGGGAGAGGATCTAATTGAAGCTCATGGAACGTTCTACACGTCTCACTGTGTCAGCTTCTGTTGCCGCAAGGAGTATAACCTGGACTGGATGAAAGATAAAATATTTTCTGATGACATTCCCCGATGTGACAAGTGCAAAAGTTTGGTGAAGCCAGATATCGTTTTCTTTGGAGAGAATCTACCTGTCCGGTTCTTCACTTCAATGAAGATGGACTTTCCCTGCTGCGATCTTCTCATCGTCATGGGGACGTCCCTGCAGGTCCAACCGTTTGCAGGTCTAGTCGGCAGGGTTTCAAAAAGTTGCCCCAGACTGCTTATTAATATGGAGAAGGCAGGGCAGGCTGATCCTCTGTTTGGGTTGTTGGGTTTTGGAGGAGGAATGGACTTTGACTCAGACAAGGCATACAGAGATGTAGCTCACATCAGTACATGTGATGAGGGCTGTTTGGCTCTAGCTGAGCTGTTGGGATGGAAGGAGGAGCTTGAAGAGTTGGTGAAGCAGGAGCATGCCAGGATTGACAGTCAGGACAAGAAAGAGAAGGCCAGTGGGAGCAAAGGAGCAGCAGCCAAGGCCAGCTCTGCATCAGTAGCACCAGAGCCAGAAAAGGAAGAGTAACTTATTAAAAAGCTCCTTTTCTAAAGAAACGCTAATGTAGTGATGTTATTGTTTGGAGTTGGCCCTTAAAGGGAGATGATGATACCAGGGTTTTTGCTTGGAAGTGAAGCTTCGACGGCTGCGGACATTTAATTCTCCTAAACAATCTCACAGGTTATGCTTCTGCTCATTTGCACTTTACTGATATTAATCTACTTTGctaatttgttttttcattaGCTTACATCTTTCTCAGCTGTATATTTATTTCTGAGGAAGTTAACTGGGCAGAGTTCTTCAAGGATGTTTACAGATCTCACAGAGCTTGGGAGGTGGTAAATATCTCTTAAACCCCGGCAGTGTGATTATGAGTTTGCTGAATTATAGAACAAGCTACTATATTGTCTCCAAACCGAATGATGAACACATCTGATTGTGTGATTTGGGCCAAGCCACTTCAACTCTCTTCACTTCTTTGAGTTGTTGATTTCAGTTTAAGCTTCCTCAAAAGATAACCAGGCTATTGTATATTGCCCCCCAAGCCGAAAtctgttggtctgattggtcaTTGACCTCTTCAAGGTATCACATTTAGCACAAATTGAATTTCCTGATAGGAGAGCTAAGGTAGTTGTTAAATGTAACAGTAGGATAGTTTGTTAATTTgaacttttaaaacatttaaaattaacACCGTTTTTCACGTTAACCTTCTGCTCCTGTTGGCTTTTAACGGTGTTTATGAGGCAAGTTGTATTTTATTAATCTTATGGAACAACAAACTGTACATGGTGCACAACATAACAGTAACTTTGCACACTCCACAGGCAGGACCATAGTTGATTTTGCTGTTTAATTCATTTTGGATAGTCAAAGTGCTGAAGAAACACAAGAAGGTTAAACTGACAAGAATTCTAAAATAAGGTGTAATTCGGTTCAAGAAGTAGTTTTTAATAGGATACTTTTGGGTTATCTAAAATAGCATGAATTGTTGCATCATGAAATACAGGGGGTGGACACGGTTACATTATCATCTATACCAAATAATGGAAACCAATACAAAAATTCTGCAATAAATTTGACCTTTGTGAAGCTGA

Function

symbol description
sirt2 Predicted to enable NAD+ binding activity; NAD-dependent histone deacetylase activity (H4-K16 specific); and tubulin deacetylase activity. Acts upstream of or within cilium assembly; hemopoiesis; and negative regulation of angiogenesis. Predicted to be located in several cellular components, including Schmidt-Lanterman incisure; main axon; and microtubule cytoskeleton. Predicted to be active in nucleus. Is expressed in liver and retina. Orthologous to human SIRT2 (sirtuin 2).

NR:

description
NAD-dependent protein deacetylase sirtuin-2-like isoform X3

GO:

id name namespace
GO:0006476 protein deacetylation biological_process
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides molecular_function
GO:0008270 zinc ion binding molecular_function
GO:0070403 NAD+ binding molecular_function

KEGG:

id description
K11412 SIRT2, SIR2L2; NAD+-dependent protein deacetylase sirtuin 2

RNA

RNA id representative length rna type GC content exon number start site end site
XM_039780820.1 True 2398 mRNA 0.43 16 19525721 19532651
XM_039780828.1 False 2348 mRNA 0.43 15 19525721 19532651

Neighbor

gene id symbol gene type direction distance location
rinl NA coding downstream 140 19515263 ~ 19525581 (-)
LOC120548698 NA coding downstream 57813 19466663 ~ 19467908 (-)
her8.2 LOC100691593,LOC105923939 coding downstream 85581 19438240 ~ 19440140 (-)
her13 LOC103373083,LOC104919393 coding downstream 91426 19431359 ~ 19434295 (-)
mrps22 mrps22,LOC103373397 coding downstream 267899 19252336 ~ 19257822 (-)
dmac2 atp5sl,LOC102790974 coding upstream 459 19533110 ~ 19536541 (-)
LOC120548388 LOC104927217,LOC101068162,LOC100693448,LOC106522132,LOC103364869,LOC101175254,LOC102216590 coding upstream 31567 19564218 ~ 19595131 (-)
nop53 NA coding upstream 65499 19598150 ~ 19609021 (-)
LOC120552636 LOC107395012,LOC103364872,LOC101485936 coding upstream 100842 19633493 ~ 19637402 (-)
psma6l LOC107094495,LOC106935416,LOC103474855,LOC103155941,LOC100701743,LOC106914191,LOC102789735 coding upstream 117390 19650041 ~ 19653824 (-)
G18127 NA non-coding downstream 120360 19383403 ~ 19405361 (-)
G18002 NA non-coding downstream 291264 19230919 ~ 19234457 (-)
G17986 NA non-coding downstream 370470 19154962 ~ 19155251 (-)
G17964 NA non-coding downstream 776320 18749198 ~ 18749401 (-)
G17936 NA non-coding downstream 932048 18592975 ~ 18593673 (-)
LOC120573122 NA non-coding upstream 5724 19538375 ~ 19541130 (-)
G18179 NA non-coding upstream 92752 19625403 ~ 19628640 (-)
G18184 NA non-coding upstream 116565 19649216 ~ 19649652 (-)
LOC120548779 coq8b,LOC103364879,LOC107395920,LOC108247334 non-coding upstream 222236 19754887 ~ 19755993 (-)
G18216 NA non-coding upstream 319253 19851904 ~ 19856310 (-)
LOC120545639 eif4g1 other downstream 1302828 18179013 ~ 18222893 (-)
zgc:165508 fam131a,LOC102799247 other downstream 1373753 18127466 ~ 18151968 (-)
LOC120552194 NA other downstream 1635060 17799999 ~ 17890661 (-)
xaf1 LOC107094331 other downstream 2046818 17472947 ~ 17478903 (-)
G17597 NA other downstream 2594727 16848161 ~ 16930994 (-)
fbxo46 fbxo46,LOC102786997 other upstream 168576 19701227 ~ 19717307 (-)
si:ch211-11n16.2 LOC104927205,LOC101481481,LOC100694251,LOC103369702,LOC107094496 other upstream 268100 19800751 ~ 19810130 (-)
LOC120547993 NA other upstream 604421 20137072 ~ 20141538 (-)
si:ch1073-340i21.1 NA other upstream 1561526 21094177 ~ 21097201 (-)
slc6a4a slc6a4,LOC103359260,LOC108228506 other upstream 1704537 21237188 ~ 21261923 (-)

Expression


Co-expression Network