LOC120546716 (calm1,LOC107396020,LOC102778633,LOC102293206,LOC103380713)



Basic Information


Item Value
gene id LOC120546716
gene name calm1,LOC107396020,LOC102778633,LOC102293206,LOC103380713
gene type coding
species eurasian perch (Perca fluviatilis)
category of species economic fish

Chromosome Information


Item Value
chromosome id NC_053129.1
NCBI id CM020926.1
chromosome length 36987114
location 11619704 ~ 11634330 (-)
genome version GENO_Pfluv_1.0_2020_eurasian_perch_Genome

Sequence


>XM_039781838.1
TCAGTTTTAGTGTGGCGGAGGGATACACAGGCAATCCCCATTCTGGCCACGGCCAATATACACACTCCTAACCCGCCAGTGGAACTCCATCTAAGGAACGACCACACTCCTAGTCTGCCTCCACAGACCAACAAGCACACAACCTATCCGACATGGCTGACCAACTAACAGAGGAGCAGATTGCAGaGTTCAAGGAGGCTTTCTCCTTATTTGACAAGGACGGTGACGGCACCATCACCACCAAAGAGCTCGGCACCGTCATGAGGTCGCTGGGCCAGAACCCCACAGAGGCCGAGCTCCAGGACATGATCAACGAGGTGGATGCTGACGGTAATGGAACCATTGACTTCCCAGAGTTCCTGACCATGATGGCCAGAAAAATGAAGGACACAGACAGCGAGGAGGAGATCCGTGAGGCTTTCCGGGTATTCGACAAGGACGGAAATGGCTACATCAGCGCTGCAGAGCTCCGTCACGTCATGACGAACTTGGGAGAGAAGCTAACGGACGAGGAGGTGGACGAGATGATCAGAGAAGCAGACATTGACGGAGACGGACAGGTCAACTACGAAGAGTTTGTACAGATGATGACTGCAAAGTGAGGCTTGCCCGCCCCGTCCTGTCCCCtcttagaagaaaaaaaaaaggaaaaaaaacaaacaaacaaat

Function


symbol description
calm1 Enables several functions, including N-terminal myristoylation domain binding activity; enzyme activator activity; and enzyme binding activity. Involved in several processes, including positive regulation of hydrolase activity; regulation of calcium ion transmembrane transport; and regulation of heart contraction. Located in microtubule cytoskeleton and sarcomere. Part of calcium channel complex and catalytic complex. Implicated in catecholaminergic polymorphic ventricular tachycardia 4 and long QT syndrome 14. Biomarker of Alzheimer's disease.

NR:

description
PREDICTED: calmodulin-like

GO:

id name namespace
GO:0022400 regulation of rhodopsin mediated signaling pathway biological_process
GO:0001975 response to amphetamine biological_process
GO:0007190 activation of adenylate cyclase activity biological_process
GO:0045087 innate immune response biological_process
GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion biological_process
GO:0051412 response to corticosterone biological_process
GO:0007202 activation of phospholipase C activity biological_process
GO:0005513 detection of calcium ion biological_process
GO:0002027 regulation of heart rate biological_process
GO:0000086 G2/M transition of mitotic cell cycle biological_process
GO:0030168 platelet activation biological_process
GO:0002576 platelet degranulation biological_process
GO:0038095 Fc-epsilon receptor signaling pathway biological_process
GO:0007268 chemical synaptic transmission biological_process
GO:0035307 positive regulation of protein dephosphorylation biological_process
GO:1901841 regulation of high voltage-gated calcium channel activity biological_process
GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction biological_process
GO:0043647 inositol phosphate metabolic process biological_process
GO:0043388 positive regulation of DNA binding biological_process
GO:1901339 regulation of store-operated calcium channel activity biological_process
GO:0008543 fibroblast growth factor receptor signaling pathway biological_process
GO:0051000 positive regulation of nitric-oxide synthase activity biological_process
GO:0048011 neurotrophin TRK receptor signaling pathway biological_process
GO:0032465 regulation of cytokinesis biological_process
GO:0005980 glycogen catabolic process biological_process
GO:0051343 positive regulation of cyclic-nucleotide phosphodiesterase activity biological_process
GO:0032516 positive regulation of phosphoprotein phosphatase activity biological_process
GO:0016310 phosphorylation biological_process
GO:0046209 nitric oxide metabolic process biological_process
GO:0006006 glucose metabolic process biological_process
GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity biological_process
GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity biological_process
GO:0007173 epidermal growth factor receptor signaling pathway biological_process
GO:0034704 calcium channel complex cellular_component
GO:0030426 growth cone cellular_component
GO:0005813 centrosome cellular_component
GO:0000922 spindle pole cellular_component
GO:0005829 cytosol cellular_component
GO:0005576 extracellular region cellular_component
GO:0005876 spindle microtubule cellular_component
GO:0005886 plasma membrane cellular_component
GO:0005654 nucleoplasm cellular_component
GO:0030017 sarcomere cellular_component
GO:0043548 phosphatidylinositol 3-kinase binding molecular_function
GO:0043274 phospholipase binding molecular_function
GO:0017022 myosin binding molecular_function
GO:0031800 type 3 metabotropic glutamate receptor binding molecular_function
GO:0005509 calcium ion binding molecular_function
GO:0008179 adenylate cyclase binding molecular_function
GO:0030235 nitric-oxide synthase regulator activity molecular_function
GO:0019904 protein domain specific binding molecular_function
GO:0050998 nitric-oxide synthase binding molecular_function
GO:0048306 calcium-dependent protein binding molecular_function
GO:0005246 calcium channel regulator activity molecular_function
GO:0072542 protein phosphatase activator activity molecular_function
GO:0031432 titin binding molecular_function
GO:0044325 ion channel binding molecular_function
GO:0016301 kinase activity molecular_function
GO:0031996 thioesterase binding molecular_function
GO:0031997 N-terminal myristoylation domain binding molecular_function

KEGG:

id description
K02183 CALM; calmodulin

RNA


RNA id representative length rna type GC content exon number start site end site
XM_039781838.1 True 669 mRNA 0.52 6 11619704 11634330

Neighbor


gene id symbol gene type direction distance location
LOC120546403 NA coding downstream 43647 11575473 ~ 11576057 (-)
LOC120547228 LOC104952422,LOC104931204 coding downstream 71354 11546186 ~ 11548350 (-)
glrx5 glrx5 coding downstream 891179 10724470 ~ 10728525 (-)
pla2g7 pla2g7,LOC102800283 coding downstream 910867 10693839 ~ 10708837 (-)
sf3b6 sf3b6,pm14,SF3B6 coding downstream 953404 10662117 ~ 10666300 (-)
LOC120547092 psmc1 coding upstream 4516 11638846 ~ 11650060 (-)
kcnk13b kcnk13,LOC106526329 coding upstream 25664 11659994 ~ 11673089 (-)
tshr tshr coding upstream 259204 11893534 ~ 11918141 (-)
nrxn3b LOC102203786,LOC101486071,LOC103457817 coding upstream 393218 12027548 ~ 12358231 (-)
trnat-ugu_2 NA coding upstream 948839 12583169 ~ 12583241 (-)
G183720 brms1l,LOC103358934 non-coding downstream 29144 11586036 ~ 11590560 (-)
G183685 NA non-coding downstream 75639 11540514 ~ 11544065 (-)
G183682 NA non-coding downstream 82253 11536271 ~ 11537451 (-)
G183665 NA non-coding downstream 119051 11500081 ~ 11500653 (-)
G183656 NA non-coding downstream 172385 11446975 ~ 11447319 (-)
G183732 NA non-coding upstream 24108 11658438 ~ 11658962 (-)
G183734 NA non-coding upstream 24724 11659054 ~ 11659573 (-)
G183747 NA non-coding upstream 64722 11699052 ~ 11699965 (-)
G183753 NA non-coding upstream 112801 11747131 ~ 11747593 (-)
G183781 NA non-coding upstream 153671 11788001 ~ 11788321 (-)
G183650 NA other downstream 245089 11374108 ~ 11374615 (-)
LOC120546776 NA other downstream 1009079 10455244 ~ 10610625 (-)
G183528 NA other downstream 1098294 10520717 ~ 10521410 (-)
LOC120546281 LOC107372644,LOC107099224,LOC106591698 other downstream 1518643 10099478 ~ 10101061 (-)
G183176 NA other downstream 2486232 9129573 ~ 9133472 (-)
ost4 NA other upstream 1272972 12907302 ~ 12908747 (-)
LOC120547209 NA other upstream 1326168 12960498 ~ 13007868 (-)
hmgn3 hmgn3,LOC104958971 other upstream 1511134 13145464 ~ 13215900 (-)
runx2b runx2,LOC102312376 other upstream 1621555 13255885 ~ 13303784 (-)
fkbp1b fkbp1b other upstream 1824272 13458602 ~ 13468065 (-)

Expression



Co-expression Network