mthfd1l (mthfd1l)


Basic Information

Item Value
gene id mthfd1l
gene name mthfd1l
gene type coding
species eurasian perch (Perca fluviatilis)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_053129.1
NCBI id CM020926.1
chromosome length 36987114
location 20891408 ~ 20928761 (+)
genome version GENO_Pfluv_1.0_2020_eurasian_perch_Genome

Sequence

>XM_039782175.1
AGACAGCCTGGTGGACATGAAAAACAGACTGGCGCGCATGGTGGTGGGGACCAGCCGCTCTGGACAGCCTGTCACCGCAGAGGACCTGAAAGAAGTGTGATGGTTAGGTGTGTCCTACATTTTTGGGTGTGAGTGGGGCACTGGCGGTGTTAATGAAAGATGCCATCAAGCCCACGTTGATGCAGACCCTAGAGGGTACGCCAGTGTTTGTCCATGCTGGGCCCTTTGCCAACATCGCCCATGGCAACTCCTCGGTGCTGGCTGACAAGCTGGCTTTAAAGTTGGTTGGACGTGACGGCTTTGTGGTGACAGAAGCTGGTTTTGGTGCAGACATCGGCATGGAGAAGTTCTTCAACATCAAATGTCGGGCTTCAGGGCTGAGGCCAAATGTGGTGGTGCTAGTTGGAACTGTCAGAGCGTTAAAGATGCACGGcggtggcccaaatgtgtCGGCAGGCGCACCTCTTCCCAAAGAGTACATTGATGAGAATCTGAGTCTTGTTGCAGGGGGTTGCCATAGCAATCTCAGGAAGCAGATCCAAATAGCACAGCTGTTCGGGGTACCAGTTGTGGTGGCACTCAATGTCTTCAAGACAGACACCCAGGCGGAGATTGACCTTGTGTGTCAGATAGCAAAAGAGTGTGGAGCATCTGATGCTGTGCCATGTCACCACTGGGCCCAGGGCGGCCGGGGTTCATTAGAGCTGGCCCAAGCTGTGAATGAGGCTGCCAGCAGACCCAGCCACTTCAAGTTCCTGTACAACATAGAGATGCCGATAGTGGAGAAGATCAGAACAATCGCCCAACAAGTGTATGGAGCTGATGACATTGAGCTGTCTCCAGAGGCCAAGGCCAAGATAGATTACTACAATCAACAGGGCTATGGTTCATTACCCATCTGCATGGCCAAGACTCACCTGTCCCTGTCCCACATGCCTGACAAGAAGGGTGTACCCACTGGATTCGTTTTGCCAATCCGAGATGTTCGTGCTAGCATTGGGGCTGGTTTCATCTTCCCACTTGTGGGAACGATGAGCACCATGCCTGGCCTGCCAACCCGACCCTGTTTCTATGACATTGACCTGGACCCGGTCACAGAGGAGATCACTGGGCTCTTCTGAGCATGCTTCAATAAATGCTATTCTCACAGGCTTCCTGTTCTGTTCTCAGGATCCTCAACTTCTCGTGTGCACCATCAGACGCATCCATCCCCTGCATCTTTGACAGGAAATTCTTTCTTACTTCCCAGGAGCCCAAACTCTCTCCACCTCACATTAACATgctctgggggaaaaaaaagattactGGAGAATTAGCTCAATGCTGTATTTGCACATCTGTGCGATATGCCAAAGATGACCTTCTACAGCCATATCGTCTATATCATATAAGCAGTATGTTTATGCTTTTGACCTCTCTGTATAATGTTTTCTGAGTATGTAAGAGTTAGTTTTAAAACCATCTTGAGTTTTATGTTGTTTACATCAacttttaatttccttttttgtgtgaaaaggTCAGTCACATGTCTTAAAACAGagctacattttttttatacatgtctTAAGCTTTTAAACTGAAATGGGCAGAGCTTGTGTATTTAACTGAATTGCTGTTGTACGCACAAAAAGCCATTATGGTGTTCATGTAAGCTCTAAATGTCCTAACCTGCTGGATGCTGCTGAATGTCCAAACTGCTGGAGTGAAAAGTTAGAATCATCAGTTTAAAGACACTTTTGAGATATTGTTCAAGTATTAACTATTATATGTTGAGAAAGCTCAAATTGAAATTGTTGTAGCAGAGGTGATGCATCCTGATACATTTTAACATGAgtttagtttgacttttttgtaTGTTGCACTTCAGAAGTATCacatctgtttgtttgttttttgaatcTTACTTTAATAGCCTTTAACAGCTCATTCCATGTATGGCATTTGCTGTGTGAAATAGCGCTTCTGCTATTTTCTCTGAaggtttcagaaacatttacaaTTACTTTATAATGTTGGTGAAGGTGGTCTGAATTTCTCTATagaactttattttacatttcatgCTCAGGTTGGGGTTTGCATTCACACAGCTGAAACTTACATTGTCAGCTGCTGGCCAACTTGTAATCTTGTTTTAATTAGCAATGTGATTAACATCCAGTGTTTTTGTTTCCTGACCACATCTCAAAGAAATGAAAATTGGTGTGGTTCTCATTTACAACAGTATGTTAAACATTTGGTTCTCAAACGTGAGTGCCTTTCAAATAAACCTTTTATTTACTCCAAAA
>XM_039782176.1
GGTGTGAGTGGGGCACTGGCGGTGTTAATGAAAGATGCCATCAAGCCCACGTTGATGCAGACCCTAGAGccttTAGGGAGTAATCCAAATCAGCAGGGGAAGGAAGCCTGGCCCACAGTCAGGCTGCCATGCCAGGTACGCCAGTGTTTGTCCATGCTGGGCCCTTTGCCAACATCGCCCATGGCAACTCCTCGGTGCTGGCTGACAAGCTGGCTTTAAAGTTGGTTGGACGTGACGGCTTTGTGGTGACAGAAGCTGGTTTTGGTGCAGACATCGGCATGGAGAAGTTCTTCAACATCAAATGTCGGGCTTCAGGGCTGAGGCCAAATGTGGTGGTGCTAGTTGGAACTGTCAGAGCGTTAAAGATGCACGGcggtggcccaaatgtgtCGGCAGGCGCACCTCTTCCCAAAGAGTACATTGATGAGAATCTGAGTCTTGTTGCAGGGGGTTGCCATAGCAATCTCAGGAAGCAGATCCAAATAGCACAGCTGTTCGGGGTACCAGTTGTGGTGGCACTCAATGTCTTCAAGACAGACACCCAGGCGGAGATTGACCTTGTGTGTCAGATAGCAAAAGAGTGTGGAGCATCTGATGCTGTGCCATGTCACCACTGGGCCCAGGGCGGCCGGGGTTCATTAGAGCTGGCCCAAGCTGTGAATGAGGCTGCCAGCAGACCCAGCCACTTCAAGTTCCTGTACAACATAGAGATGCCGATAGTGGAGAAGATCAGAACAATCGCCCAACAAGTGTATGGAGCTGATGACATTGAGCTGTCTCCAGAGGCCAAGGCCAAGATAGATTACTACAATCAACAGGGCTATGGTTCATTACCCATCTGCATGGCCAAGACTCACCTGTCCCTGTCCCACATGCCTGACAAGAAGGGTGTACCCACTGGATTCGTTTTGCCAATCCGAGATGTTCGTGCTAGCATTGGGGCTGGTTTCATCTTCCCACTTGTGGGAACGATGAGCACCATGCCTGGCCTGCCAACCCGACCCTGTTTCTATGACATTGACCTGGACCCGGTCACAGAGGAGATCACTGGGCTCTTCTGAGCATGCTTCAATAAATGCTATTCTCACAGGCTTCCTGTTCTGTTCTCAGGATCCTCAACTTCTCGTGTGCACCATCAGACGCATCCATCCCCTGCATCTTTGACAGGAAATTCTTTCTTACTTCCCAGGAGCCCAAACTCTCTCCACCTCACATTAACATgctctgggggaaaaaaaagattactGGAGAATTAGCTCAATGCTGTATTTGCACATCTGTGCGATATGCCAAAGATGACCTTCTACAGCCATATCGTCTATATCATATAAGCAGTATGTTTATGCTTTTGACCTCTCTGTATAATGTTTTCTGAGTATGTAAGAGTTAGTTTTAAAACCATCTTGAGTTTTATGTTGTTTACATCAacttttaatttccttttttgtgtgaaaaggTCAGTCACATGTCTTAAAACAGagctacattttttttatacatgtctTAAGCTTTTAAACTGAAATGGGCAGAGCTTGTGTATTTAACTGAATTGCTGTTGTACGCACAAAAAGCCATTATGGTGTTCATGTAAGCTCTAAATGTCCTAACCTGCTGGATGCTGCTGAATGTCCAAACTGCTGGAGTGAAAAGTTAGAATCATCAGTTTAAAGACACTTTTGAGATATTGTTCAAGTATTAACTATTATATGTTGAGAAAGCTCAAATTGAAATTGTTGTAGCAGAGGTGATGCATCCTGATACATTTTAACATGAgtttagtttgacttttttgtaTGTTGCACTTCAGAAGTATCacatctgtttgtttgttttttgaatcTTACTTTAATAGCCTTTAACAGCTCATTCCATGTATGGCATTTGCTGTGTGAAATAGCGCTTCTGCTATTTTCTCTGAaggtttcagaaacatttacaaTTACTTTATAATGTTGGTGAAGGTGGTCTGAATTTCTCTATagaactttattttacatttcatgCTCAGGTTGGGGTTTGCATTCACACAGCTGAAACTTACATTGTCAGCTGCTGGCCAACTTGTAATCTTGTTTTAATTAGCAATGTGATTAACATCCAGTGTTTTTGTTTCCTGACCACATCTCAAAGAAATGAAAATTGGTGTGGTTCTCATTTACAACAGTATGTTAAACATTTGGTTCTCAAACGTGAGTGCCTTTCAAATAAACCTTTTATTTACTCCAAAA
>XM_039782177.1
TATGCCGATGTCTTCACATTTCCGACTGCCCCTGAAGAGTATACCTCCATCAGGACCCTGTGTTGACTCGCCCCCTCAACTTTCTTTTTGTTCCTCCTGGAGGTTGAATCCCTCGCTAACCACCGTAAGACCAACAAAGAGAAGAAAACCGTATACGCCACAATTACAAAACTAAAAGTAACGTGAAGTTACTTAGTTAGTAAGCCATGAAGTTGTCTATAATGCGTAGTGCTTGTGGCAGCCTTCGGATACATTCAGCCTGTCCAGGCAGCAGGGTCAGCGGCTTGACACGGAGATGCCTACCGGTTGGTCCTGCCAACAACCGTTTGATCCTCCGGACAGCAAGCGCTAGCAGCGGCGGTACCAGCAACAAATTAGCCGTCAGCTTTGGAAAACAGTCTCAAAATGGTGATGGGTTTGACTGCGACAGTTCTTTGAGGGAAGTGGTTCAAAGCACCAAGGAGGCAATGTTGGCACTGCAGGGAAGAAATCCAGTAGTCCAACCATTGTTAGTCATTATACAGgcaggTGAAGATGACCAATTGTTGGAGATCAATAAGAAAATGGCAGGAAGGATTGGCTTAAACATCACCCAGATTTGTCTGGCAAAGGAATGCAGTGAAGATGAAaTTGTAGAGGAGGTGTTGAAGCTGAATGAAGACCCCAGGGTGCACGGAGTCTACCTCCACCTCCCCCCTGCCTACATCACCAGTCGAGTGTTGAACACAATCAAACCTGAGAAGGATGTAGACGGGATATCCGATTTGAATATGGGCCGTCTGGTACGAGGACACCTAAGCAAAGGCTTTGTGCCACCCATAGCCAGCGCTGTGCTGGATCTGCTGGAGAAACATGATTCTGCTTTGGAAGGGAAAACTGTGTTGCTTGTTGGAGGAGAAGGACCCCTTGGGGTGTCCCTGCAGTGCCTGATTGAAAGAAGTGGAATGGTAGCTCTCAAGGGTCAGTGGAGCTCAAAAAGCCTACGGAGACAGGCGATGCAGGCTGATGCTGTGGTCCTGTTAGGGGCAGGGAACATGGATCTTCCCCCCACCTGGGTTAGACCAGGGGCTGCTGTCATCCGCTGTGAGCCCACACTGGAGACAGATGAACATGCCGTTGAGATGTCCTCAAAGTCTGGGTTAGGATATCTCACAGCAGCTTACAGATCACAGAATGTGGTGGGTAGTTGCAGTCGGTGGCTCCAGGAGCAGCAGTACCGACCCTGGCATCTGCACAGCCTCAAACTGCAGCCCCTGACCCCTGTACCAAGTGACATAGAGATTTCCAGAGCTCAGACACCCAAGCCAGTGGACCAGCTGGCTGAGGAGATTGGTTTGCTGCCAGAGGAGCTTGAAGCCTATGGCAGGAGCAAAGCTAAGGTCCGACTCTCCTTGTTGGACCGCCTCCACAAACAGCCGGATGGGAAATATGTACTGGTTGCTGGTATAACTCCCACCCCACTGGGTGAAGGTAAAAGCACGGTGACCATCGGCCTAGTCCAGGCCCTGTCTGCCCACCTTAAGCTCAACTCCTTCGCCTGTCTCCGACAGCCTTCCCAGGGACCCACCTTTGGGGTTAAAGGGGGAGCTGCAGGAGGGGGATATGCCCAGGTCATCCCTATGGAGGAggtaaattttttccccacTGGTGACATTCATGCCATTACAGCAGCCAACAACCTGGTGGCAGCAGCCATCGATGCCAGAATGCTCCACGAGGCGACTCAATCAGACAAGGCCCTGTTCAATAGACTGGTCCCTTCAGTGAATGGAGTCCGAAGATTTTCACCCATCCAAATCTCCAGGCTACGTCGTTTAGGGATCAATAAAATAGATCCTGCATCTCTCACACCGCAGGAAGTCAGCACCTTTGTTCGTCTTGACCTGGACCCCTCCAAGATCACCTGGCAGAGAGTTGTTGACACAAATGACCGTTTCTTGAGGAAGATCACAGTAGGACAGGCGAGCACTGAAAAAGGACAGATCAGAGAGACTGGGTTCGACATTGCAGTGGCCAGCGAGATCATGGCCATCCTGGCCCTGGCAGACAGCCTGGTGGACATGAAAAACAGACTGGCGCGCATGGTGGTGGGGACCAGCCGCTCTGGACAGCCTGTCACCGCAGAGGACCTGGGTGTGAGTGGGGCACTGGCGGTGTTAATGAAAGATGCCATCAAGCCCACGTTGATGCAGACCCTAGAGGGTACGCCAGTGTTTGTCCATGCTGGGCCCTTTGCCAACATCGCCCATGGCAACTCCTCGGTGCTGGCTGACAAGCTGGCTTTAAAGTTGGTTGGACGTGACGGCTTTGTGGTGACAGAAGCTGGTTTTGGTGCAGACATCGGCATGGAGAAGTTCTTCAACATCAAATGTCGGGCTTCAGGGCTGAGGCCAAATGTGGTGGTGCTAGTTGGAACTGTCAGAGCGTTAAAGATGCACGGcggtggcccaaatgtgtCGGCAGGCGCACCTCTTCCCAAAGAGTACATTGATGAGAATCTGAGTCTTGTTGCAGGGGGTTGCCATAGCAATCTCAGGAAGCAGATCCAAATAGCACAGCTGTTCGGGGTACCAGTTGTGGTGGCACTCAATGTCTTCAAGACAGACACCCAGGCGGAGATTGACCTTGTGTGTCAGATAGCAAAAGAGTGTGGAGCATCTGATGCTGTGCCATGTCACCACTGGGCCCAGGGCGGCCGGGGTTCATTAGAGCTGGCCCAAGCTGTGAATGAGGCTGCCAGCAGACCCAGCCACTTCAAGTTCCTGTACAACATAGAGATGCCGATAGTGGAGAAGATCAGAACAATCGCCCAACAAGTGTATGGAGCTGATGACATTGAGCTGTCTCCAGAGGCCAAGGCCAAGATAGATTACTACAATCAACAGGGCTATGGTTCATTACCCATCTGCATGGCCAAGACTCACCTGTCCCTGTCCCACATGCCTGACAAGAAGGGTGTACCCACTGGATTCGTTTTGCCAATCCGAGATGTTCGTGCTAGCATTGGGGCTGGTTTCATCTTCCCACTTGTGGGAACGATGAGCACCATGCCTGGCCTGCCAACCCGACCCTGTTTCTATGACATTGACCTGGACCCGGTCACAGAGGAGATCACTGGGCTCTTCTGAGCATGCTTCAATAAATGCTATTCTCACAGGCTTCCTGTTCTGTTCTCAGGATCCTCAACTTCTCGTGTGCACCATCAGACGCATCCATCCCCTGCATCTTTGACAGGAAATTCTTTCTTACTTCCCAGGAGCCCAAACTCTCTCCACCTCACATTAACATgctctgggggaaaaaaaagattactGGAGAATTAGCTCAATGCTGTATTTGCACATCTGTGCGATATGCCAAAGATGACCTTCTACAGCCATATCGTCTATATCATATAAGCAGTATGTTTATGCTTTTGACCTCTCTGTATAATGTTTTCTGAGTATGTAAGAGTTAGTTTTAAAACCATCTTGAGTTTTATGTTGTTTACATCAacttttaatttccttttttgtgtgaaaaggTCAGTCACATGTCTTAAAACAGagctacattttttttatacatgtctTAAGCTTTTAAACTGAAATGGGCAGAGCTTGTGTATTTAACTGAATTGCTGTTGTACGCACAAAAAGCCATTATGGTGTTCATGTAAGCTCTAAATGTCCTAACCTGCTGGATGCTGCTGAATGTCCAAACTGCTGGAGTGAAAAGTTAGAATCATCAGTTTAAAGACACTTTTGAGATATTGTTCAAGTATTAACTATTATATGTTGAGAAAGCTCAAATTGAAATTGTTGTAGCAGAGGTGATGCATCCTGATACATTTTAACATGAgtttagtttgacttttttgtaTGTTGCACTTCAGAAGTATCacatctgtttgtttgttttttgaatcTTACTTTAATAGCCTTTAACAGCTCATTCCATGTATGGCATTTGCTGTGTGAAATAGCGCTTCTGCTATTTTCTCTGAaggtttcagaaacatttacaaTTACTTTATAATGTTGGTGAAGGTGGTCTGAATTTCTCTATagaactttattttacatttcatgCTCAGGTTGGGGTTTGCATTCACACAGCTGAAACTTACATTGTCAGCTGCTGGCCAACTTGTAATCTTGTTTTAATTAGCAATGTGATTAACATCCAGTGTTTTTGTTTCCTGACCACATCTCAAAGAAATGAAAATTGGTGTGGTTCTCATTTACAACAGTATGTTAAACATTTGGTTCTCAAACGTGAGTGCCTTTCAAATAAACCTTTTATTTACTCCAAAA

Function

symbol description
mthfd1l Predicted to enable methenyltetrahydrofolate cyclohydrolase activity and methylenetetrahydrofolate dehydrogenase (NADP+) activity. Predicted to be involved in tetrahydrofolate interconversion. Predicted to act upstream of or within one-carbon metabolic process. Predicted to be active in cytosol. Is expressed in anterior neural tube and optic cup. Human ortholog(s) of this gene implicated in neural tube defect. Orthologous to human MTHFD1L (methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like).

NR:

description
monofunctional C1-tetrahydrofolate synthase, mitochondrial isoform X2

GO:

id name namespace
GO:0009396 folic acid-containing compound biosynthetic process biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0004329 formate-tetrahydrofolate ligase activity molecular_function

KEGG:

id description
K13402 MTHFD1L; monofunctional C1-tetrahydrofolate synthase, mitochondrial

RNA

RNA id representative length rna type GC content exon number start site end site
XM_039782175.1 False 2288 mRNA 0.44 12 20904635 20928761
XM_039782176.1 False 2228 mRNA 0.44 11 20905503 20928761
XM_039782177.1 True 4295 mRNA 0.48 28 20891408 20928761

Neighbor

gene id symbol gene type direction distance location
LOC120547338 NA coding upstream 9821 20878480 ~ 20881587 (+)
epm2a epm2a coding upstream 252694 20628841 ~ 20638714 (+)
LOC120546927 LOC104961664 coding upstream 268777 20617250 ~ 20622631 (+)
slc22a16 slc22a16 coding upstream 898522 19977864 ~ 19992886 (+)
cdc40 cdc40,LOC103135076 coding upstream 947377 19919473 ~ 19944031 (+)
akap12b akap12,LOC102289546,LOC102211499,LOC102799877 coding downstream 8757 20937518 ~ 20980163 (+)
armt1 armt1 coding downstream 63705 20992466 ~ 20996625 (+)
esr1 esr1 coding downstream 70813 20999574 ~ 21012236 (+)
myct1a myct1,LOC103355010 coding downstream 231195 21159956 ~ 21162886 (+)
serac1 serac1,LOC102777075 coding downstream 234457 21163218 ~ 21170361 (+)
G186035 utrn non-coding upstream 132602 20746317 ~ 20758806 (+)
G186025 NA non-coding upstream 188764 20693170 ~ 20702644 (+)
LOC120546929 NA non-coding upstream 263143 20626548 ~ 20628265 (+)
LOC120546242 NA non-coding upstream 531799 20261785 ~ 20359609 (+)
LOC120546509 NA non-coding upstream 918065 19950611 ~ 19973343 (+)
LOC120546176 NA non-coding downstream 60544 20989305 ~ 20991418 (+)
G186088 LOC103355013 non-coding downstream 91060 21019821 ~ 21023878 (+)
G186094 syne1,LOC103355013,LOC106946714 non-coding downstream 103880 21032641 ~ 21033182 (+)
G186106 NA non-coding downstream 131996 21060757 ~ 21061976 (+)
LOC120546175 NA non-coding downstream 222683 21151444 ~ 21153184 (+)
kif25 LOC104961976,LOC100703631 other upstream 1031191 19852643 ~ 19860217 (+)
acp1 acp1 other upstream 1243252 19633500 ~ 19648156 (+)
zgc:193593 NA other upstream 1270625 19572573 ~ 19620783 (+)
nhsl1b nhsl1,LOC101470763 other upstream 1349576 19429595 ~ 19541832 (+)
si:dkey-206f10.1 LOC103360989,LOC103380838 other upstream 1502185 19367720 ~ 19389223 (+)
gtf2h5 gtf2h5 other downstream 242187 21170948 ~ 21172639 (+)
erh erh,LOC100699790,LOC101174968 other downstream 1015982 21944743 ~ 21947000 (+)
G186394 mycn,LOC108233328 other downstream 1057018 21985779 ~ 22065589 (+)
lin28b lin28b other downstream 1352206 22280967 ~ 22301585 (+)
kcns3b kcns3,LOC103372653 other downstream 1879118 22807879 ~ 22810520 (+)

Expression


Co-expression Network