bmp2b (bmp2)



Basic Information


Item Value
gene id bmp2b
gene name bmp2
gene type coding
species eurasian perch (Perca fluviatilis)
category of species economic fish

Chromosome Information


Item Value
chromosome id NC_053129.1
NCBI id CM020926.1
chromosome length 36987114
location 13981265 ~ 13987401 (-)
genome version GENO_Pfluv_1.0_2020_eurasian_perch_Genome

Sequence


>XM_039782651.1
TCAATTCAACCACTACGCTGTGGCGCACAGAGGAGAGGCGACGCGCTCCCAAACTCGGTCCAACAAGGTCCGAGGAGCGACACTTGAGTGCGCTTATCTCTCTTAAAGCCAGGCTCCGCTCAACTTTGTGTCTCTGCGAACTGTTCTCTTTTGAAGATGTTCAACCAACATGCTTTATACTTAGATCGGTCCTGCCTACGCGAACCCGCTTCCTCATAGacttaacatattttttttccccctttctttCCGTGCTGACCAAGACCTAACCCGAATTTTGCAGCTGGTGAGAATATGTGCGAGAGGCGATCGGCGAAGGGCATGGACTGTCTTTGGTCCCTCACGGAGAAGCAGCGTGGATTAAACGCGAATTAATGTGGAATTTATCGGAGCCCCAAGGTGGAACGACGACCGGACACAGCGCTTCCTCGTCAGGGACTGACTGATCATGGTCGCCGTGGTCCGCTCTCTCATGGTACTGCTGCTCGCTCAGGTGTTGCTGGAAGGTGCTGCGGGACTTATCCCCGAGGTCGGCCGGAGGAAATACAGCGAATCCGGGAAGCAGACCCCAGAGCAGTCGGAGAGCTTCTTCAACGAGTTTGAGCTTCGGCTTCTCAATATGTTTGGACTGAGGCGCAGGCCGACCCCGAGCAAGCAAGCCGTGGTGCCGCAGTACATGGTGGACCTTTACCGCATGCACTCAGCAAACGGAGACCACATCTCGAAACGACCCAAGAGCATGGGGAAACACGCAGAGAGAGCCGCCAGCAAGGCCAACACGATTAGAAGCTTTCACCATGAAGAGTCTATGGAGGCCCTGGCCAGGCTGAAAGGCAAAACGACCCAGCAGTTCTACTTCAACCTCACTTCTATCCCTGATGAGGAGCTCATCACCTCTGCAGAGCTACGTGTCTACAGGGATCAGGTGATGGGAGCTGCACCCCCCAACAACAGCTCAAGAAACAGCAGCACCAGTAATAGCGCTCCTGGCTTCCATCGTATCAACATTTACGAGATATTCGGAGTTCCTGCCACTCAAAGTAGGGAACCTCTGGCACGTCTGCTGGACACTCGGCTAGTGCAGGACTCTTTGAGCCGCTGGGAAAGCTTCGACGTCAGCCCTGCTGTATCCCAGTGGACCTCTGGGAAAGGTCACAACCATGGCTTTATGGTGGAGGTGCTTCACCCAGAGGAAGGGGAGATGGATGGGGAGCACGCCCAGAGACGTAGTAGGCACATCAGGGTGAGCCGGTCCCTGCACCAGGACCGGGACTCGTGGCCTCAGGCTCGGCCTCTACTGGTGACGTATGGCCATGACGGCCGTGGGGACTCGGTACTCCACACACGGGAAAAACGTCAGGCAGCACTCCGCAAACAGCGCAGGAAGCAGCAGCACAAGGCCAGCTGCAAGAGACATGCCCTGTACGTGGACTTCAGTGATGTGGGGTGGAACGAGTGGATAGTGGCGCCCCCTGGCTACCACGCCTTTTATTGCCAAGGGGAATGTCCGTTCCCTCTAGCAGACCACCTTAATTCTACCAATCATGCCATTGTGCAGACGCTGGTCAACTCAGTCAACTCGAACATCCCCAGAGCCTGTTGTGTGCCCACTGACCTCAGCCCCATCTCCCTGCTCTACCTGGATGAATACGAGAAGGTGATCCTGAAAAACTACCAGGATATGGTGGTGGAGGGATGTGGCTGCCGGTGAGAAACGAACAGTGGcatggaaagaaagagaaagtgggcaagagagacagaaagagacatcaGAGGTTATTATGGACACCCGGTTTCCCAATGAAGACGTTTATTTAtatgaaagacaaaacagaGCTAttgtggaagaagaagaaaaaaaactatatatgaatatatttatGTCTACGTAAAGTtgggaaaaataaatattttaatcagaGGAAAAATCCTTTACTggttttgaaaatgtatttgtgatGTACATTTCGAAATGGGTGCAATACCACATGAAGTATAATGctcagatttttattttgtatttatttctat

Function


symbol description
bmp2 Enables several functions, including BMP receptor binding activity; co-receptor binding activity; and phosphatase activator activity. Involved in several processes, including regulation of cellular biosynthetic process; regulation of signal transduction; and transmembrane receptor protein serine/threonine kinase signaling pathway. Acts upstream of or within several processes, including animal organ development; positive regulation of cellular metabolic process; and regulation of transmembrane receptor protein serine/threonine kinase signaling pathway. Located in cell surface; extracellular space; and intracellular membrane-bounded organelle. Part of BMP receptor complex. Implicated in bone disease (multiple); hemochromatosis type 1; otosclerosis; prostate cancer; and tooth agenesis. Biomarker of prostate cancer and prostate carcinoma.

NR:

description
PREDICTED: bone morphogenetic protein 2

GO:

id name namespace
GO:0001710 mesodermal cell fate commitment biological_process
GO:0060876 semicircular canal formation biological_process
GO:0055015 ventricular cardiac muscle cell development biological_process
GO:0001503 ossification biological_process
GO:0045168 cell-cell signaling involved in cell fate commitment biological_process
GO:0051216 cartilage development biological_process
GO:0048264 determination of ventral identity biological_process
GO:0030509 BMP signaling pathway biological_process
GO:0040007 growth biological_process
GO:0007368 determination of left/right symmetry biological_process
GO:0001889 liver development biological_process
GO:0060030 dorsal convergence biological_process
GO:0030903 notochord development biological_process
GO:0042664 negative regulation of endodermal cell fate specification biological_process
GO:0005615 extracellular space cellular_component
GO:0005125 cytokine activity molecular_function
GO:0042803 protein homodimerization activity molecular_function
GO:0046982 protein heterodimerization activity molecular_function
GO:0008083 growth factor activity molecular_function

KEGG:

id description
K21283 BMP2; bone morphogenetic protein 2

RNA


RNA id representative length rna type GC content exon number start site end site
XM_039782651.1 True 2031 mRNA 0.52 3 13981265 13987401

Neighbor


gene id symbol gene type direction distance location
fermt1 fermt1 coding downstream 24127 13946704 ~ 13957138 (-)
trmt6 trmt6 coding downstream 36432 13938613 ~ 13944833 (-)
LOC120546266 slc23a2,LOC100699458,LOC101468039,LOC108231760,LOC106518547,LOC102297661 coding downstream 63141 13911571 ~ 13918124 (-)
gpcpd1 gpcpd1 coding downstream 71133 13889340 ~ 13910132 (-)
napbb napb,LOC103381049,LOC102194491,LOC102306363,LOC106518545,LOC102225024,LOC103457862,LOC107097573,LOC107378120 coding downstream 94095 13877232 ~ 13887170 (-)
pak5 pak5,LOC102790572 coding upstream 257040 14244441 ~ 14322141 (-)
LOC120547016 LOC103375044,LOC104947369,LOC101079388,LOC102209315 coding upstream 348238 14335639 ~ 14359390 (-)
magl NA coding upstream 373112 14360513 ~ 14378555 (-)
LOC120546406 NA coding upstream 392613 14380014 ~ 14381177 (-)
LOC120546407 NA coding upstream 400119 14387520 ~ 14388443 (-)
G184162 NA non-coding downstream 138788 13842272 ~ 13842477 (-)
LOC120546199 NA non-coding downstream 582690 13339183 ~ 13398575 (-)
G184049 NA non-coding downstream 662335 13318488 ~ 13318930 (-)
G184026 NA non-coding downstream 730829 13249591 ~ 13250436 (-)
G183981 NA non-coding downstream 946768 13034252 ~ 13034497 (-)
G184204 plcb1 non-coding upstream 131621 14119022 ~ 14141806 (-)
G184208 NA non-coding upstream 200027 14187428 ~ 14231705 (-)
G184217 plcb4 non-coding upstream 235574 14222975 ~ 14225219 (-)
LOC120546499 NA non-coding upstream 251025 14238426 ~ 14243275 (-)
G184224 NA non-coding upstream 261813 14249214 ~ 14328936 (-)
mfsd2b mfsd2b other downstream 490122 13473683 ~ 13491143 (-)
fkbp1b fkbp1b other downstream 513200 13458602 ~ 13468065 (-)
runx2b runx2,LOC102312376 other downstream 677481 13255885 ~ 13303784 (-)
hmgn3 hmgn3,LOC104958971 other downstream 765365 13145464 ~ 13215900 (-)
LOC120547209 NA other downstream 973397 12960498 ~ 13007868 (-)
G184299 LOC101066055,LOC100706360,LOC102203025 other upstream 484800 14472201 ~ 14498370 (-)
naa30 naa30,LOC102795089,LOC104960600 other upstream 583979 14571380 ~ 14612946 (-)
LOC120547045 LOC103359896,LOC104919819,LOC100704859,LOC107378087,LOC104956714 other upstream 669776 14657177 ~ 14667601 (-)
rps29 NA other upstream 1122839 15110240 ~ 15111479 (-)
si:dkey-177p2.18 LOC102081001,LOC102302990,LOC107088471,LOC105937616,LOC105357244,LOC102210773,LOC101470269,LOC104966503 other upstream 1801425 15788826 ~ 15795638 (-)

Expression



Co-expression Network