XLOC_004978 (plaub)



Basic Information


Item Value
gene id XLOC_004978
gene name plaub
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007123.7
NCBI id CM002896.2
chromosome length 49182954
location 46740584 ~ 46766300 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00009738
GTTGGTGCACAGCTGGAAGTTTCAGAATGTggaAGGATGATGTGCTGGACATTGAGATCAAGTACATCCACTGCAGCAGTGCGTTTGAGAAGCTGGCTCAGAGTGAGACAAGCTCCTCCTCCCCCTgtgccagcagccaatcagaagagAGCAGCCTCTATAAAGGAGTGTTTTCAAACCAGCAGCTGGATAAACCACTGCTGATCTGATctctcacacagGTAGAGGCGAGATGTCTGGAATTCTCGTGTGGAGTTTGATTCTGGCTTTAACAGCTCTCACGGTGTGTAAAGCTCAGCGCAGACCCTTTCCCAGTGAATCCCATGATAAACCAGGTGTCTTGTGTCTGAATGGAGGATCGTCTCTATCTTCTCTGTCTGGTCGGCATCTTCTCTGTCTCTGTGCTGAAGGCTTCAGTGGCTCCAGATGTGAAACAGACACATCGGTCTCCTGCTTCGATGGGATTGGTCAGCTCTACGTGGGACCCGTGTCTAAATCAGCCAGTGGGAGGGAATGTCTGGAATGGGATTCAGAGAAAGCGCTTGAAATCGGAGTTTATCTCAAGAGTCTGATCGTGGGTggacacaaacactgcagAAACCCAGACTTCAGCCGAAGACCGTGGTGTTTCGTAAAGACGCCATCCGGGATCATGAAAGAGGACTGTGATATTCCACGCTGCTCTAAAGATCACGGATCTGATCAGGACAGTCTGGCAGTTTCACAGTCAGGCTGGAGGTGTGGTCAGGCAGAGGGGCGGAGCATGAAGGTAGTGGGCGGTGCTTTGAGCATGTTGGAGAGACACCCGTGGATGGCGGCGATTTACAGCAGAAAATCTCGTGGGAGATTTTTCACCTGCGGCGGGAGTCTGATCTCACCCTGCTGGATACTGACAGCAGCTCACTGCTTCCCTGATGGGGCTCAGACTCTTGTCCATAAACTCTCAGTGGTTCTGGGAAAGAAGGCCATAAACGAGACGGATGTTCAGAGCGAGCAGGAGTTCAGGGTCTCTGAGCTCTTCATCCATGAACACTTCGACAACACTGACGGAAACTTCAACAACGACATCGCTCTGTTGAAGATTCGTGGTCCTGATGGCCGCTGTGCTAAAGAGTCGAGTTCAGTGAAGACGGTCTGCATTCCTGGACCCAACGTGTCGCTCAGTGATGGGACGTCCTGTACGGTGACGGGATACGGCAGAGAACATGAAGGGTCGTGGTTTTACTCTCAGTATCTCAAAGAAGCACAGGTCAAGATTTTGTCTCAGGATTTGTGTTCGAGTAAAGAGTATTATGGCAACATGATCACCGAGAACATGCTGTGTGCCGGCAGCCCAGACTGGAGCTCAGATGCCTGTAAGGGTGACTCTGGCGGGCCGCTGGTCTGTCGTGTCCAGGACCGAGTGTTTCTCTTCGGTGTGGTCAGCTGGGGTGAAGGATGCTCCAGAGCGTTTCGGCCTGGTGTTTATGCCAAAGTCAGCAACTACTACCACTGGATCCTGGAGAAGAGCGGCCTGACCTCACTCTCATgatcacacccacacacacagttaacgtctgaattattagcccctctgtatgtttttacccaatttctgtttaacagagagaaggttttttcaacacatttctaaacataatagttctaacaactgatttatttcatctttgccatgatgacagcacataatagactagatattcttaaaagtactagtattcagctgaaagtgacatttaaaggcttcactaggttaattagggtaaagttagggtaattaggcaagtctttgtaaagcagtgatttgttctggagacaatccaaaactaatattgcttaagggggctaataatattgaccttaaaatgggtttaaaagaattaataactgcttttattctagccgaaataaataaaactttccagaagaaaaaatattataggaaatactgtgaaaaatttctgaatctgttcaacatcatttgagaaataatagaaaaaaggaggggcataattctgactttagctgtatatgCTCTGCCATCTCATTGTAGTTCATTTACTGTAGATCAGTTACCTATAATCTGCTAGTCAGTACTGTATTGCATGTGTTGAAAGCAGCAAATAGTTTTAGTAAGTATTATTTAGAAAGTGTTagtttccattgtttttaaactgtacagCGTAACTTTGTAGACGTTTCTCTTTTGtctattttaattttcttttgttgtgTAACTACATACAATGACACTGGCCAAGTCAGAAACAGgccaataaacatttttaaataccttTTC
>TCONS_00009739
ttatttaacaagtcatttgtaactcattaattaacagtttattaatgatctataaACTAGGTATAACAGATAGTTATTACAAAGTGTTACCGAATGTTCAATAATTAATCAGACTCCTTCAACCTTTGTTTCTTAGATTATCATTGtagcaaaaaaaaagatgttttgaaaaatgttgcaaaaatcattgacttccatagtaggaaaaacaaatacagaagtcaatgattacaggtttccaacattcttcaaaatatcttcatttgtgatcGCCAGAGTGAAAGAATAACAttctcaaactggtttggaacattTTTATGGGAagttaatgatgacagagtttgcattttggggtgaactatacctttaaacaaGTGTTTTTAGGTTAAGAATTATTTCAAATAGTGTTGGACAGAAGCAGAGTGTCAGGAGATTTCTAATATTATGGAGAATGCTGGGTTATTTGAGTCATTCTAGTGATTCAGTGAAGTGGTTTCAGTTTGTTTGCAGACAAGCTCCTCCTCCCCCTgtgccagcagccaatcagaagagAGCAGCCTCTATAAAGGAGTGTTTTCAAACCAGCAGCTGGATAAACCACTGCTGATCTGATctctcacacagGTAGAGGCGAGATGTCTGGAATTCTCGTGTGGAGTTTGATTCTGGCTTTAACAGCTCTCACGGTGTGTAAAGCTCAGCGCAGACCCTTTCCCAGTGAATCCCATGATAAACCAGGTGTCTTGTGTCTGAATGGAGGATCGTCTCTATCTTCTCTGTCTGGTCGGCATCTTCTCTGTCTCTGTGCTGAAGGCTTCAGTGGCTCCAGATGTGAAACAGACACATCGGTCTCCTGCTTCGATGGGATTGGTCAGCTCTACGTGGGACCCGTGTCTAAATCAGCCAGTGGGAGGGAATGTCTGGAATGGGATTCAGAGAAAGCGCTTGAAATCGGAGTTTATCTCAAGAGTCTGATCGTGGGTggacacaaacactgcagAAACCCAGACTTCAGCCGAAGACCGTGGTGTTTCGTAAAGACGCCATCCGGGATCATGAAAGAGGACTGTGATATTCCACGCTGCTCTAAAGATCACGGATCTGATCAGGACAGTCTGGCAGTTTCACAGTCAGGCTGGAGGTGTGGTCAGGCAGAGGGGCGGAGCATGAAGGTAGTGGGCGGTGCTTTGAGCATGTTGGAGAGACACCCGTGGATGGCGGCGATTTACAGCAGAAAATCTCGTGGGAGATTTTTCACCTGCGGCGGGAGTCTGATCTCACCCTGCTGGATACTGACAGCAGCTCACTGCTTCCCTGATGGGGCTCAGACTCTTGTCCATAAACTCTCAGTGGTTCTGGGAAAGAAGGCCATAAACGAGACGGATGTTCAGAGCGAGCAGGAGTTCAGGGTCTCTGAGCTCTTCATCCATGAACACTTCGACAACACTGACGGAAACTTCAACAACGACATCGCTCTGTTGAAGATTCGTGGTCCTGATGGCCGCTGTGCTAAAGAGTCGAGTTCAGTGAAGACGGTCTGCATTCCTGGACCCAACGTGTCGCTCAGTGATGGGACGTCCTGTACGGTGACGGGATACGGCAGAGAACATGAAGGGTCGTGGTTTTACTCTCAGTATCTCAAAGAAGCACAGGTCAAGATTTTGTCTCAGGATTTGTGTTCGAGTAAAGAGTATTATGGCAACATGATCACCGAGAACATGCTGTGTGCCGGCAGCCCAGACTGGAGCTCAGATGCCTGTAAGGGTGACTCTGGCGGGCCGCTGGTCTGTCGTGTCCAGGACCGAGTGTTTCTCTTCGGTGTGGTCAGCTGGGGTGAAGGATGCTCCAGAGCGTTTCGGCCTGGTGTTTATGCCAAAGTCAGCAACTACTACCACTGGATCCTGGAGAAGAGCGGCCTGACCTCACTCTCATgatcacacccacacacacagttaacgtctgaattattagcccctctgtatgtttttacccaatttctgtttaacagagagaaggttttttcaacacatttctaaacataatagttctaacaactgatttatttcatctttgccatgatgacagcacataatagactagatattcttaaaagtactagtattcagctgaaagtgacatttaaaggcttcactaggttaattagggtaaagttagggtaattaggcaagtctttgtaaagcagtgatttgttctggagacaatccaaaactaatattgcttaagggggctaataatattgaccttaaaatgggtttaaaagaattaataactgcttttattctagccgaaataaataaaactttccagaagaaaaaatattataggaaatactgtgaaaaatttctgaatctgttcaacatcatttgagaaataatagaaaaaaggaggggcataattctgactttagctgtatatgCTCTGCCATCTCATTGTAGTTCATTTACTGTAGATCAGTTACCTATAATCTGCTAGTCAGTACTGTATTGCATGTGTTGAAAGCAGCAAATAGTTTTAGTAAGTATTATTTAGAAAGTGTTagtttccattgtttttaaactgtacagCGTAACTTTGTAGACGTTTCTCTTTTGtctattttaattttcttttgttgtgTAACTACATACAATGACACTGGCCAAGTCAGAAACAGgccaataaacatttttaaataccttTTCAATATTTTTTGTAGCCCCACAGAAGTTATTTTCTACACAAAGAAAGCATATTCAATGCAAGTGACGTGTGTATTTTTAGTAAGTAagcaatgtttatatatatagcgcatttattgtgtatggccatacacccaaagtgcttcataATCAtgaggggggagggggggtctctctacaccaccaccagtgtgcagctccacacTCCACAACAGtgtcagtgcgctcaccacacaccagctataaggggagtgaagagacagtgatagagccaaatcagtggatggggatgattgggaggccttgATAGTTAAGATAGAGGGAGTTtggcactcactggccactttattaggtacacctgtccaactgctcgttaacgcaaatttgtaatcagccaatcacatggcagcagctcaatgcatttaggcgtgtagacatggtcaagacgatctgctgcagttcaaagcgagcatcagaatggggaagaaaggggatttaggtgactttgaacgtggcatggttgttggtgccagacgggctgctctgagtatttcagaaactgctgatctactgggattttcacacacaaccatctctagggtttacagagaatggtctgacaaataGATAAtatgcagtgagcggcagttctgtgggcgcaaatgccttgttgatggccagaggtcagaggagaatggccagactggttccagctgatagctgaatctctgccacgaaggattaaagcagttctgaaggcaaaagggggtccaacccagtactagtaaggtgtacctaataaagtggccagtgagtgtagtctTTAGAGTCATTTTGACCCATTAGAGTGTGAACAGGTCTTACGTGTTATaagtgaatctgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtatcacagaGACAAAGATTGTCTTGAGCTTTTTAAGCACATCTAACATGCTTCTGCCTGTTTAATCTCTTCCAGCGCTACATTTAATCCACGaacacctaaacacacacacacacaccctgagtATAATTCCATGTATGGgtagtggctggaagggcatccactgcgtaaaacatattccgGAATatttgacggttcattctgctgtggcgacccctgataaataagggactaagctgaagcaaaattaataaaacacacacacacacacacgtttgtttttgtgaaaagtggggacattacataggtttccattcatatTATACTGTCCAAGAggacaggagactgtgtgcagctttactctctgattaaactcatcctgtaggatttataagcattttgagaaatgaggacgtcaccaatatcctcatatttcacctcccttttgtaatacccgtgtcatacctatgtcattatacagatttgtgtcctgatatgtcacaaaaacacacatacacaaacacacacacatactcgtacTGAACATAGAATCACTGAACTTTACACACAACTGCTGCAGTGATTTACCAATGGGGAAAGAGTGTGTAAATGTCAGTATGATCACAGTagcaactttgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgcgtgcgtgcgtgcgtgcgtgcgtgcgtgcgtgcgtgtgtgtgtgtgtgcgcgtgtgtgtgtgcgtgcgtgcgtgcgtgcgtgcgtgcgtgttcaGTCCAGATGGTGAGTCAGTTTAAAGCACTGATGATGTCACTCAGTATTAATCTCTCTCTGCAGCTTCATGTAGAAACACTGAACAATATTAtaacttctttattttgtttacattattagTTTAAAGacttctagttttttttttttgttataaatatttgtgtttatttttccgggtgctccggtttcccccacagtccaaacacatgcgctatagacgagttgaataaactaaattgtccgtggtgtatgactgtgtatgaatgtttcccagtggaggggcatccgctgtgtaaaaacatatgctggaatagttggcggttcattccgctgtggagatccctgatgaataaacacccatagcaaaatttctctggcccacaccATCAGCATTTGCTCATATGCCGCAGTGACTTACAGctcatgactggaccaagtctggcttccatacaagaggcaaacatggaccatatctgggtcaagtctcagccaagttgataacccataactgggcctgaactgggccagatatgttggtgtgtcatgactgcaatgtttttataaacccttgaagcatttcgctttatggcTGTGCTTTTCCATGAAGCGACCTGATTAATAGAATTATTTCTGTACTCAAAAATAGTTTCAATGTATTTTAGAAGTGGGTCAGGACAGGCTTACGTGACCCACATATACacttttaacatctgggccaaatactacatttgatatctggcccaagtcttgagtgccgcctgtaagacggtgccacctcacccaaacctgggccatgtttggt
>TCONS_00009740
GTAGAGGCGAGATGTCTGGAATTCTCGTGTGGAGTTTGATTCTGGCTTTAACAGCTCTCACGGTGTGTAAAGCTCAGCGCAGACCCTTTCCCAGTGAATCCCATGATAAACCAGGTGTCTTGTGTCTGAATGGAGGATCGTCTCTATCTTCTCTGTCTGGTCGGCATCTTCTCTGTCTCTGTGCTGAAGGCTTCAGTGGCTCCAGATGTGAAACAGACACATCGGTCTCCTGCTTCGATGGGATTGGTCAGCTCTACGTGGGACCCGTGTCTAAATCAGCCAGTGGGAGGGAATGTCTGGAATGGGATTCAGAGAAAGCGCTTGAAATCGGAGTTTATCTCAAGAGTCTGATCGTGGGTggacacaaacactgcagAAACCCAGACTTCAGCCGAAGACCGTGGTGTTTCGTAAAGACGCCATCCGGGATCATGAAAGAGGACTGTGATATTCCACGCTGCTCTAAAGATCACGGATCTGATCAGGACAGTCTGGCAGTTTCACAGTCAGGCTGGAGGTGTGGTCAGGCAGAGGGGCGGAGCATGAAGGTAGTGGGCGGTGCTTTGAGCATGTTGGAGAGACACCCGTGGATGGCGGCGATTTACAGCAGAAAATCTCGTGGGAGATTTTTCACCTGCGGCGGGAGTCTGATCTCACCCTGCTGGATACTGACAGCAGCTCACTGCTTCCCTGATGGGGCTCAGACTCTTGTCCATAAACTCTCAGTGGTTCTGGGAAAGAAGGCCATAAACGAGACGGATGTTCAGAGCGAGCAGGAGTTCAGGGTCTCTGAGCTCTTCATCCATGAACACTTCGACAACACTGACGGAAACTTCAACAACGACATCGCTCTGTTGAAGATTCGTGGTCCTGATGGCCGCTGTGCTAAAGAGTCGAGTTCAGTGAAGACGGTCTGCATTCCTGGACCCAACGTGTCGCTCAGTGATGGGACGTCCTGTACGGTGACGGGATACGGCAGAGAACATGAAGGGTCGTGGTTTTACTCTCAGTATCTCAAAGAAGCACAGGTCAAGATTTTGTCTCAGGATTTGTGTTCGAGTAAAGAGTATTATGGCAACATGATCACCGAGAACATGCTGTGTGCCGGCAGCCCAGACTGGAGCTCAGATGCCTGTAAGGGTGACTCTGGCGGGCCGCTGGTCTGTCGTGTCCAGGACCGAGTGTTTCTCTTCGGTGTGGTCAGCTGGGGTGAAGGATGCTCCAGAGCGTTTCGGCCTGGTGTTTATGCCAAAGTCAGCAACTACTACCACTGGATCCTGGAGAAGAGCGGCCTGACCTCACTCTCATgatcacacccacacacacagttaacgtctgaattattagcccctctgtatgtttttacccaatttctgtttaacagagagaaggttttttcaacacatttctaaacataatagttctaacaactgatttatttcatctttgccatgatgacagcacataatagactagatattcttaaaagtactagtattcagctgaaagtgacatttaaaggcttcactaggttaattagggtaaagttagggtaattaggcaagtctttgtaaagcagtgatttgttctggagacaatccaaaactaatattgcttaagggggctaataatattgaccttaaaatgggtttaaaagaattaataactgcttttattctagccgaaataaataaaactttccagaagaaaaaatattataggaaatactgtgaaaaatttctgaatctgttcaacatcatttgagaaataatagaaaaaaggaggggcataattctgactttagctgtatatgCTCTGCCATCTCATTGTAGTTCATTTACTGTAGATCAGTTACCTATAATCTGCTAGTCAGTACTGTATTGCATGTGTTGAAAGCAGCAAATAGTTTTAGTAAGTATTATTTAGAAAGTGTTagtttccattgtttttaaactgtacagCGTAACTTTGTAGACGTTTCTCTTTTGtctattttaattttcttttgttgtgTAACTACATACAATGACACTGGCCAAGTCAGAAACAGgccaataaacatttttaaataccttTTCAATA

Function


symbol description
plaub Predicted to enable serine-type endopeptidase activity. Acts upstream of or within plasminogen activation. Predicted to be active in extracellular space. Is expressed in several structures, including eye; gill; gonad; heart; and liver. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease (multiple); Quebec platelet disorder; end stage renal disease; lung disease (multiple); and mitral valve prolapse. Orthologous to human PLAU (plasminogen activator, urokinase).

GO:

id name namespace
GO:0031639 plasminogen activation biological_process
GO:0006508 proteolysis biological_process
GO:0016310 phosphorylation biological_process
GO:0033628 regulation of cell adhesion mediated by integrin biological_process
GO:0005576 extracellular region cellular_component
GO:0005615 extracellular space cellular_component
GO:0016740 transferase activity molecular_function
GO:0004252 serine-type endopeptidase activity molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0008233 peptidase activity molecular_function
GO:0008236 serine-type peptidase activity molecular_function
GO:0016301 kinase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-030619-15 Predicted to enable serine-type endopeptidase activity. Acts upstream of or within plasminogen activation. Predicted to be active in extracellular space. Is expressed in several structures, including eye; gill; gonad; heart; and liver. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease (multiple); Quebec platelet disorder; end stage renal disease; lung disease (multiple); and mitral valve prolapse. Orthologous to human PLAU (plasminogen activator, urokinase).

Ensembl:

ensembl_id ENSDARG00000039145

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00009738 False 2299 mRNA 0.45 14 46740584 46763820
TCONS_00009739 False 5182 mRNA 0.43 12 46742805 46766300
TCONS_00009740 True 2082 mRNA 0.45 11 46745239 46763824

Neighbor


gene id symbol gene type direction distance location
XLOC_004977 exoc7 coding upstream 1475 46696867 ~ 46739109 (+)
XLOC_004976 tvp23b coding upstream 44745 46683114 ~ 46695839 (+)
XLOC_004975 trim16 coding upstream 61107 46634736 ~ 46679477 (+)
XLOC_004974 FADS6 coding upstream 108591 46605600 ~ 46631993 (+)
XLOC_004973 CABZ01111725.1 coding upstream 137029 46603441 ~ 46603555 (+)
XLOC_004979 vclb coding downstream 25607 46791907 ~ 46835940 (+)
XLOC_004980 adkb coding downstream 75618 46841918 ~ 46868634 (+)
XLOC_004981 hpdl coding downstream 102971 46869271 ~ 46881002 (+)
XLOC_004982 fam53b coding downstream 117485 46883785 ~ 46937956 (+)
XLOC_004983 oat coding downstream 194279 46960579 ~ 47042081 (+)
XLOC_004970 NA non-coding upstream 197395 46542671 ~ 46543189 (+)
XLOC_004963 NA non-coding upstream 508713 46188296 ~ 46231871 (+)
XLOC_004962 NA non-coding upstream 638164 46078647 ~ 46102420 (+)
XLOC_004961 FO904966.2 non-coding upstream 676821 46046268 ~ 46063763 (+)
XLOC_004984 NA non-coding downstream 269421 47035721 ~ 47036420 (+)
XLOC_004991 NA non-coding downstream 813722 47580022 ~ 47580566 (+)
XLOC_004992 NA non-coding downstream 840571 47606871 ~ 47610330 (+)
XLOC_005002 NA non-coding downstream 1562566 48328866 ~ 48330894 (+)
XLOC_005005 NA non-coding downstream 1648227 48414527 ~ 48419991 (+)

Expression



Co-expression Network