tgfbr1b (tgfbr1,LOC103376883,LOC102779975,LOC108248259)


Basic Information

Item Value
gene id tgfbr1b
gene name tgfbr1,LOC103376883,LOC102779975,LOC108248259
gene type coding
species eurasian perch (Perca fluviatilis)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_053133.1
NCBI id CM020930.1
chromosome length 31697812
location 5854640 ~ 5895766 (+)
genome version GENO_Pfluv_1.0_2020_eurasian_perch_Genome

Sequence

>XM_039790046.1
CCTCAGCGCTGTGAGAAGTTAGCAGTCGGCTGGCAGATTGGTCCGTAGCCACGATGGATGCAATACCATGCCTTCTGTTTGTCCTCCTGTTCGGGACACGGATACAAGAACATACCGCCCTCCAGTGTTACTGTGACCGCTGCAGCGCCAACTCCAGCTGCAGCACCGATGGCGTCTGCTTCGTCGCCATCCGTAAGTCGGGCGGccagctgaccactgagcagcgCCAGTGTGTGCACGAAAACGAACTGATCCCGCGAGACAGGCCCTTCATCTGTGCCCCATCCGTCAAACAAGACAAGGGCATTTACCCCTTGTGCTGCACCACGGACAACTGCAACGAAAAGCCTAAACTGGATATCATTcctgTACCCACAGTGAAGACCCCTCCTCTGGGCCCCGTGGCCCTGGCAGCGGTGATTGCCGGccccgtgtgtgtgttctgcctGCTGCTGGTCCTGGCCTTCTAcgtctgccacagccacagggGTCTGGGGGCCGGCGGTGCAGGggcccaccaccaccaccaccgggTGCCCAACGAAGAGGACCCCTCCATGGACCACCCCTTCATCACCGTGGGAACAACGCTGAAAGACCTCATCTATGACATGACCACCTCGGGCTCTGGATCAGGCCTGCCGCTGCTGGTCCAGAGGACTATCGCCAGGACCATCATCCTCCAGGAGAGCATCGGGAAGGGCCGATTCGGGGAGGTGTGGCGGGGTAAGTGGCGTGGCGAGGAGGTGGCCGTGAAGATCTTCTCCTCCCGTGAGGAGCGCTCCTGGTTCCGCGAGGCCGAGATCTACCAGACGGTGATGCTGAGACACGAGAACATTCTGGGCTTCATCGCTGCTGACAACAAAGaTAACGGCACGTGGACTCAGCTGTGGCTGGTGTCGGACTACCACGAGCACGGCTCCCTGTTTGACTACCTGAACCGCTACACAGTCACTGTGGAGGGCATGATCAAACTGTCCCTGTCCACCGCCAGCGGCCTCGCACACCTCCACATGGAGATAGTGGGGACACaagGGAAGCCAGCCATTGCACACAGAGACCTGAAGTCCAAGAACATCCTggtgaagaagaacgggacgtgCTGCATCGCCGACCTGGGGCTGGCCGTCCGCCACGACTCGGCCACCGACACCATCGACATCGCTCCAAACCACAGAGTGGGAACCAAAAGGTATATGGCTCCGGAGGTACTGGACGACTCCATAAACATGAAACACTTTGAGTCTTTCAAGCGAGCGGACATCTACGCCATGGGCCTGGTGTTCTGGGAGATCGCCAGCCGCTGCTCTATGGGAGGCATCCATGAGGACTACCAGCTGCCCTACTACGACCTGGTCCAGTCGGATCCATCAGTGGAGGAGATGAGGAAGGTGGTGTGTGAGCAGAAGCTTCGGCCCAACATTCCCAACCGCTGGCAGAGCTGTGAGGCCCTGCGGGTGATGGCCAAGATCATGAGGGAGTGTTGGTACGCCAACAGTGCCGCCCGACTCACCGCTCTGCGGATCAAGAAAACCCTGTCTCAGCTCAGCCAACAGGAGGGCATCAAGATGTAGACATCcctaccaaacacacacacacacacacacacacacacacacacacacacacacacacacacacacacacacacctctgactGGCATCCATATCGTTATCATTACAGCATTATTATCttcattattattcatttgCTGTGCCCCCTTTGGTTCGAAGGGAACTGAAGACTTTGCCCCCTGagctctttttttctcatcCCATTTCCTTCATTGACAAACTGATGAGTCGTGAACgtgaggaggtgtgtgtgtgtgggtgcgtgtgtgtgtgtgtgtgtgtgtgtgtgcgtgtgtgtgtgcgtgtgcgcgcgtgtggTGCACTGTGCTGACGTGCAcacaggatggatggatggatggatggatggatggatctaATGAGGGAGGGCCGCGAGCCATTAAAGGATATCCTCCATCCTCCTTTGCTACATTCATCACATGGGACCCATCTCAAGTCCCGCCTCCACCACTCATCACAACCAATAAGAGCTCAGAGCCCGTCAGGTTACCATTAGGCAAGCCAGGCAGCTGGGAATCAGCTGGGCGGCCTCATTGTATATCAGCATTAGAGAGCTAAGCTACTCTTCAGTAGGGCTGCACCTCGCTCATTCACATCTTTGAAGAGCGCTGCGAGTCATGGGAAATGTCCTCCCACCGGAAACGAGCCCAAGGGAACTTTTGGAATAGATCCATGTGATTTGTGGCATTAGCATGATATGTACATATTTGAATGTGTGAGGTGCATAATTGGTTCTGATCACAGGGACGCTGAGCAGTGTAACATGTACCACACTTGAGTGACCTGCTAGTCAAATCCAAAGACAAACGGGATGAACAGTGCACATTTGGTCCGACGTGCTCTGTGGTTTAGAGGTGGAGCTTTGTTCCACTGGTCCGCAGCTGTCGGAGCCGCTCAGCCATGATCCAGAGTATTTCAGAGAGTAAAGGTGGCGTTgtgtgcagccctactgttgAGTTGTCTTACAGTAGCATTGGGAACTGAAGCGTGGACCCGGGGGTTATGGGACGCTCTGTAAGCCGCCCTGCGGGCTCCTTCATCGCTTTAgttctctctcatctctgcaACGCGTTTGCACTGTTGTATATCCGTCACTCCCCCAGGGAGTCGGACAGGTCAGtttaatttattgtttgtttgttttttcaattttcGTTTTGGTGGCAggggatcttttttttttttttttttttttgctaaactAAACTGGACATGATGACCTCATTCATTTTTGGCGAACATGATCAACATATGCAATATACAGTAGATAAATGTGTCTATTTTCTATACTGTGCTCTGCTAAACCACAAACCGCAAGAACAACAGCAACAGCGCTCAGCTGCCACCATGCCTTCCAACCAGCTGTTACCGGAAAGTGCCAGTGCTTTAACAACCCAACTCCTCTCATGTCGgctgggtgggtgtgtgtgtgtgtgtgtctgtgtgtgacacgctgtgtgtttgtgtgtatgtgtcagagAAGAGGCCTGCCGAGCACACAGCGCGCTCGTACTATGCACACCCAAGAAAATAGGTACGCAAAGCAAGGAGGGGACACACAGCAGCGTCACAGCACCCCAAGTCCAGCCGACTCTCTGGTGCCATCACAACCCCCCCCCTCACCGACACCGACCACCTCAGCAACAACTCATCGTGCAGCGAGTCTGGACAACACGCTCCAGCACCTCAAACTGTGTTTATTTGGAAAGATAATGCCACAGAAGCTGGCGGCGGCTTTGgaaaaaagacacaaagactTGTAAGCATTACTGATGTTGCCCTATAAATGTAAACTCTTGGATTTCTGATTTTTGATCCTTTCATGTCAACTTTTTTCTCCTCCTGTAGGATAATCATCAACAAGGAggtacattcattcatttaaatataGCAAACGGAGATTTACTAAGCCATAGATTTTCCAGGttatgtataattttttttcttcttttttgtggcAAGGTCTTTtctactataaaaaaaaaaaaagatgaaaatgaaaatgtgcatcaaaaggacaattttgtcattTCAGCTTAGCAAGCCTTAAGGGACCAACACATAAGAGTCAGGATCTGctcttattctttctttctttatttgtgtttttagtttttaatgaaaaaagatttatatatacatatactatatAATTGATTACTATGATAAATGTGTCATTATTCTATctaaaggacaaaaaaaatatatgcagCACCcgatttcacagtttgtttcgGTCAAGTGTTTGTCCTTTTGCCAGGTTGCGATACATCTGAACGCGCGGACTGACTTTACAGAGATGTGTCCCGAGTTCCACCGGAAGCACTTGTCTTTTTAGGACAAGTCAAAGCAAGTCCGTGATGAGATCCAGTTTAAATGCACAGCATGAAGCAGTCAGTGATGAATACACCGAGTCAAAGAGTCTTTCGATTGTTCAGCAATAAGTGCACTTGTGAACCACTGCAGGGTTGAGTCGGTCTGTCTCCGTTGTTTGTCTTTGCGGTTTATTGATGTGCTGCTACGTAGTTGTCCGCCTCGCTTCCCGAGCGGAGGCGAGAGCTGGCGTTGGATGTAAATACCTTTCAGGTCGTCTGAATCTGATCATTTTTGTGCCATGTTGCTCCGACGCGAAACCAGCTCGTCGTCAACGAGGAGTTGTCGTTCTCTGCTTGGCGGTGTTCGGCGAGAATGGAAAGCTGCGACCTCCGTGGGCCGTGGTGGGAAGCCACTGAGTACACGCATACCGAACAGCACGGTTCGAAATCCACTGAAAGCTAGTTTCTTCTACTAGGAGTGTAGAGGAGGGCGAGGAACAAAGACATCCACTTCTGGTTGAGTAAAGTCCTTACAGTAACTGATCATGTCAAATAGATGGATAATGTCCTAATAATCTGGCATACATCCCGTGTAATGTCATTATTAGCATTAATGCCTTTCTTCAGGAGAAGCTCAGTGCCCATTTCTTTGCAGACAGCACTTTGACATGGATGTCACAACCGGTTGAGTCGTGAAATCCATGCCATGGATGTCACAACTCAACCGGTTGAGTCATTAGCACTAACATGGATTCCATGTTAGTGCTAATGACTCAACCGGTTGTTTTTGGGTTGATTCAGAGCCTCCCGTCATCCTTTTTAAACTTTGGTAAGAAAGAACCCAAAGTTTGACAAATAGCAGACACATTGGGATGTAGTTCACTGGTCCGAGtcgtgaatttttttttttttttagttttttttaaatatgtagaaATGGTCAGCAGTGGCAGAATGTGACACATTATTGTAAATATACAAAAGAAGAAAGTTGCCTGATCTTTGAAGAAAGTGAAGTGGAACTCGCTGCTATATTAAATACAAAAAGGGTGACGGACTA

Function

symbol description
tgfbr1 Enables several functions, including ATP binding activity; I-SMAD binding activity; and transforming growth factor beta receptor activity, type I. Contributes to transforming growth factor beta binding activity. Involved in several processes, including positive regulation of macromolecule metabolic process; positive regulation of signal transduction; and protein phosphorylation. Located in several cellular components, including bicellular tight junction; endosome; and membrane raft. Part of receptor complex. Implicated in Ferguson-Smith tumor; Loeys-Dietz syndrome 1; Lynch syndrome; and urinary bladder cancer.

NR:

description
TGF-beta receptor type-1-like isoform X2

GO:

id name namespace
GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway biological_process
GO:0035556 intracellular signal transduction biological_process
GO:0023014 signal transduction by protein phosphorylation biological_process
GO:0006468 protein phosphorylation biological_process
GO:0016020 membrane cellular_component
GO:0005524 ATP binding molecular_function
GO:0004702 obsolete signal transducer, downstream of receptor, with serine/threonine kinase activity molecular_function
GO:0005024 transforming growth factor beta-activated receptor activity molecular_function

KEGG:

id description
K04674 TGFBR1, ALK5; TGF-beta receptor type-1

RNA

RNA id representative length rna type GC content exon number start site end site
XM_039790046.1 True 4968 mRNA 0.50 9 5854640 5895766

Neighbor

gene id symbol gene type direction distance location
reck reck coding upstream 37013 5750881 ~ 5817627 (+)
trnas-gcu_66 NA coding upstream 263557 5591002 ~ 5591083 (+)
trnas-gcu_65 NA coding upstream 264749 5589807 ~ 5589891 (+)
trnas-gcu_64 NA coding upstream 266112 5588447 ~ 5588528 (+)
trnas-gcu_63 NA coding upstream 267302 5587256 ~ 5587338 (+)
lancl2 lancl2 coding downstream 14111 5909877 ~ 5928609 (+)
vopp1 vopp1 coding downstream 38254 5934020 ~ 5948852 (+)
mpp7a mpp7,LOC106534949 coding downstream 384836 6280602 ~ 6454013 (+)
odad2 armc4,LOC104966301,LOC108229284 coding downstream 586708 6482474 ~ 6549264 (+)
mkxa mkx,LOC103377095 coding downstream 671964 6567730 ~ 6594030 (+)
G218067 LOC107382602,LOC104967228 non-coding upstream 97219 5722808 ~ 5757421 (+)
G218060 NA non-coding upstream 224422 5629711 ~ 5630218 (+)
G218039 NA non-coding upstream 363272 5491143 ~ 5491368 (+)
G218031 NA non-coding upstream 432292 5421974 ~ 5422348 (+)
G218026 NA non-coding upstream 606954 5247295 ~ 5247686 (+)
G218083 NA non-coding downstream 57343 5953109 ~ 5954354 (+)
G218141 NA non-coding downstream 189298 6085064 ~ 6085649 (+)
G218150 NA non-coding downstream 333009 6228775 ~ 6228976 (+)
G218155 NA non-coding downstream 354972 6250738 ~ 6258612 (+)
G218190 NA non-coding downstream 552382 6448148 ~ 6449203 (+)
trdmt1 LOC104946219,LOC101070638 other upstream 1331934 4511713 ~ 4522706 (+)
ppp1r17 NA other upstream 1593042 4256048 ~ 4261598 (+)
chchd7 chchd7,LOC102799933 other upstream 2150265 3670420 ~ 3704375 (+)
G217723 cnn3 other upstream 2310855 3495450 ~ 3543785 (+)
LOC120552392 mtpap other upstream 2620818 3220615 ~ 3233822 (+)
LOC120552660 NA other downstream 1464840 7360606 ~ 7373347 (+)
LOC120552265 LOC101478037,LOC102216221,LOC100695799 other downstream 2627533 8523299 ~ 8596356 (+)
G218441 LOC101478037,LOC102216221,LOC100695799 other downstream 2655017 8550783 ~ 8606578 (+)
G218445 NA other downstream 2660450 8556216 ~ 8557253 (+)
rnpc3 NA other downstream 3316152 9211918 ~ 9230163 (+)

Expression


Co-expression Network