apex1 (apex1)


Basic Information

Item Value
gene id apex1
gene name apex1
gene type coding
species eurasian perch (Perca fluviatilis)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_053134.1
NCBI id CM020931.1
chromosome length 29109922
location 21890610 ~ 21894722 (-)
genome version GENO_Pfluv_1.0_2020_eurasian_perch_Genome

Sequence

>XM_039792520.1
TAAGCACAGCCACAGCAAGCACGTTGTAGCTGTGCTTTTGTGAGTGTGTTTAGGGTGCAGTGACTGACCGACTGACTGAAAAGATCCACTTGGCTGGTCTTTGCATCCTGTTGTTCAAGTGCAACGGCGCgtgtgctgttgtgtgtgcgtgttgtgtgtCTGCGAGGTGTGTTTGCAGTCAGAGCGAGTTCAAATATGAAGAGAGGCAAGAAGGAAGAGGACGCAGCTGCAGATGGGGACAATGACACCGGCTCTGCTTctgcaaagaaaacaaagaaggcTAAGGAACCAGAGGCCCCAATAATGTACGATGATCCTCCTGACAAAATGACCAGCAAAGATGGACGTGAAGCCAACATGAAGATCACCTCCTGGAACGTCGACGGCCTGAGGGCCTGGGTGAAAAAGAAGGGCCTGGATTGGGTGCGTGAGGAGGCTCCAGATGTTTTGTGCCTGCAGGAGACAAAGTGTGCAGAGAAATCCCTCCCTGCTGACATCACCTCAATGCCAGAGTACCCTCACAAGTACTGGTCCGCATCAGATGAAAAGGAGGGTTACAGTGGTGTGGCAATGCTCTGCAAGACTGAACCCCTAAAAGTCACCTATGGCATCGGTAACGAAGAGCATGACAAGGAGGGCCGCGTCATCACCGCCGAGTTCCCCAACTTCTTCCTGGTGACCGCCTATGTGCCAAACTCCGGCAGAGGCCTCGTGCGCCTCGACTACCGCAAAACCTGGGACGTGGACTTCCGGGCGTATCTGAGCGAGCTGGACATGCAGAAGCCCCTGGTGCTGTGCGGCGACCTTAACGTTGCGCACCAGGAGATCGACCTGAAGAACCCGAAGGGGAACAAGAAGAACGCCGGCTTCACCCCCGAGGAGCGCGAGGGCTTCGGCCAGCTGCTGGAGTCCGGTTTCATCGACAGCTTCCGTGAGCTTTACCCCGAGCAGGCCAACGCCTACACCTTCTGGACCTACATGATGAACTCGCGCGGAAAGAATGTGGGCTGGAGGCTTGACTACTTTGTACTGTCGTCCAGTCTGCTGCCAGGCCTGTGCGACAGCAAGATTCGCAACAAGGCCCTGGGAAGCGACCACTGCCCCATCACTCTGCACATAGCTGTGTAGGTCAGTGTCCGAGAACGGCTACAGATTTACATAGCCTTCACTGTTTTCTTAGTACTTCCGTTCCTACTCGGCTGAAACTATCATGTATGCTAGTGTGCGTTAGAGTGAGGCCTGTTTGTGCAGGGAAGTCTTACATTTGTTGGGAGTTTCTCACACTTTACAAACTCATTCCTTCAGTAGGCTCAACGGTAGCCTAGTGTATACTCTGTAatactttttcagttttcacaTGAAACTTTAATAAAATGACTCCACGGCACAATTCATACTGCTCATTTATCCTCTTCATACAATTGAAGTTTGTCAATAAACCCAGTGATGTACACCTCATTTCGGCTGTTCTCTAAAAACGCAACACTATTACTCGTAGATGTTTGAAGATGATTTTTAACAACCTGTGCCACAGGCTCCTGTTTGTACTACTGCCGACCTGAGACCTCCATGCAACATAGCCTGTAGTACATTTGTGTTACTGTCCGAAATGGAGAACattgctgttaaaaaaaaaaaaatgtaactaaaaATGTTTTAAGCCTCTTTTCcaaagcattgttttttttctgttgtaaaACATGCCCAAAATAAAGACTGGatttatgtttc

Function

symbol description
apex1 Predicted to enable DNA-(apurinic or apyrimidinic site) endonuclease activity; double-stranded DNA 3'-5' exodeoxyribonuclease activity; and phosphodiesterase I activity. Acts upstream of or within several processes, including heart contraction; heart looping; and negative regulation of apoptotic process. Predicted to be located in endoplasmic reticulum; mitochondrion; and nuclear lumen. Predicted to be active in nucleus. Is expressed in head. Human ortholog(s) of this gene implicated in breast cancer; female reproductive organ cancer (multiple); spina bifida; and urinary bladder cancer. Orthologous to human APEX1 (apurinic/apyrimidinic endodeoxyribonuclease 1).

NR:

description
PREDICTED: DNA-(apurinic or apyrimidinic site) lyase

GO:

id name namespace
GO:0090305 nucleic acid phosphodiester bond hydrolysis biological_process
GO:0006281 DNA repair biological_process
GO:0005622 intracellular anatomical structure cellular_component
GO:0004519 endonuclease activity molecular_function
GO:0003677 DNA binding molecular_function

KEGG:

id description
K10771 APEX1; AP endonuclease 1

RNA

RNA id representative length rna type GC content exon number start site end site
XM_039792520.1 True 1731 mRNA 0.49 5 21890610 21894722

Neighbor

gene id symbol gene type direction distance location
selenoo2 LOC106935628,LOC103357121,LOC107081058 coding downstream 54014 21829011 ~ 21836596 (-)
LOC120553085 LOC103357120 coding downstream 62676 21816182 ~ 21827934 (-)
LOC120553490 ano4,LOC102780176 coding downstream 137339 21684210 ~ 21753271 (-)
slc38a4 slc38a4 coding downstream 319497 21518625 ~ 21571113 (-)
gas2l3 gas2l3 coding downstream 525502 21335537 ~ 21365108 (-)
si:ch211-214j24.10 LOC103357125,LOC104922658 coding upstream 33517 21928239 ~ 21935396 (-)
LOC120553803 LOC103357126 coding upstream 42616 21937338 ~ 21945575 (-)
nav3 nav3 coding upstream 54014 21948736 ~ 22179107 (-)
zdhhc17 zdhhc17,LOC102798393 coding upstream 639532 22534254 ~ 22573905 (-)
LOC120553033 LOC103354931,LOC102080527,LOC102775588,LOC101467455 coding upstream 981201 22875923 ~ 22893181 (-)
G229541 NA non-coding downstream 10390 21879904 ~ 21880220 (-)
G229539 NA non-coding downstream 11905 21878272 ~ 21878705 (-)
G229527 LOC108228952,LOC107098074,LOC105922964,LOC106609550,LOC103375704 non-coding downstream 34321 21854383 ~ 21856289 (-)
LOC120553093 NA non-coding downstream 112934 21777033 ~ 21777676 (-)
G229413 NA non-coding downstream 208071 21681560 ~ 21682539 (-)
G229546 NA non-coding upstream 17683 21912405 ~ 21947509 (-)
G229558 NA non-coding upstream 425551 22320273 ~ 22320528 (-)
LOC120553112 NA non-coding upstream 487043 22381765 ~ 22449387 (-)
G229576 NA non-coding upstream 561467 22456189 ~ 22456445 (-)
G229589 csrp2 non-coding upstream 620268 22514990 ~ 22531298 (-)
LOC120553090 NA other downstream 79513 21771088 ~ 21811097 (-)
slc38a2 slc38a2 other downstream 416008 21461076 ~ 21474602 (-)
ptprz1b NA other downstream 745077 21063691 ~ 21145533 (-)
G229199 NA other downstream 932390 20957657 ~ 20958220 (-)
cdk17 LOC104930593 other downstream 1535983 20301092 ~ 20354627 (-)
G229716 NA other upstream 1210038 23104760 ~ 23239573 (-)
glipr1a NA other upstream 1309046 23203768 ~ 23210497 (-)
LOC120553170 NA other upstream 1795797 23690519 ~ 23711804 (-)
G229907 NA other upstream 1804975 23699697 ~ 23700198 (-)
LOC120553046 NA other upstream 1963497 23858219 ~ 23863974 (-)

Expression


Co-expression Network