XLOC_005039 (map2k4b)


Basic Information

Item Value
gene id XLOC_005039
gene name map2k4b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007123.7
NCBI id CM002896.2
chromosome length 49182954
location 281166 ~ 287633 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00009819
CGCACCGCTGCTTATCGGGAGTTCTGGCGCACCTGGCAACCTCCgcgactcctccagaaactgctGTCCGCCTCTGAAGCGTCGATCACCGCGGGCGGATGGGGAGCGCACCGCTGCTCCGGCCGTTCCAGTAGAGTCGCGTGTGCGTCAGAAACAGTGGCGGAGAATCGAGCGCGTGAAGGCGGACTCCGCAGATCCACAATGGCGGCTCCCAGCAGTGACTCTGGCTCTTCGTGCGGTGGCGGCGGTACTGCGGGACCAGCGGGACTCTCACCGCGACTCGGCTCCATCGGTGCTCAGGATTCAAACTCCTGCTGGCGCTGTCAGAATGAAACAGGGTTTCAGATCAATCTGTCTGGAGTAACCCAAATCAAACGCAAAGCGCTGAAGCTGAACTTTGCCAATCCGCCAGTGAAGCCGGCGGCGCGTCTGCCCATCACCAGCACTGCACCGGCCTTCCAGAACCCACACATAGAGCGGTTGCGGACACACAGCATCGAGTCTTCAGGCAAACTGAAGATTTCTCCAGAACAGCATTGTGATTTCACGGCCGAGGACCTCAAGGATCTGGGGGAGATCGGGAGAGGAGCGTACGGATCCGTCAACAACATGGTGCACAAACCCAGCGGGCAGATCATGGCTGTCAAGAGGATTCGCTCCACGGTGGATGAGAAAGAGCAGAAGCAGCTGCTGATGGATCTGGACGTGGTGATGAGGAGCTCCGACTGCCCATACATCGTACAGTTCTACGGCGCTCTCTTCAGagagggcgACTGCTGGATCTGTATGGAGCTCATGGCTACCTCCCTCGACAAGTTCTACAAATATGTATATTGTGCGTCAGATGACGTCATTCCAGAGGAAATATTAGGCAAAATTACATTAGCAACTGTGAAAGCACTGAATCACTTGAAGGAAAACTTGAAAATAATCCACAGAGACATCAAGCCCTCCAATATTCTCCTGGACAGAAACGGCAACATTAAGCTGTGTGATTTCGGCATCAGCGGGCAGCTGGTGGACTCCATCGCCAAGACCAGAGACGCCGGCTGCAGACCCTACATGGCTccTGAACGCATCGACCCCAGCGCCTCCAGACAGGGCTACGATGTGCGCTCAGACGTCTGGAGTTTGGGAATCACACTGtatgAGCTGGCCACGGGCCGCTTCCCGTACCCGCGCTGGAACAGTGTGTTTGATCAGCTGACGCAGGTGGTGAAGGGGGAGCCGCCGCAGCTCTGCAGCTCTGAGGACCGACAGTTCTCACACAAGTTCATCCAGTTCGTCAACCtatgCCTTACGAAGGACGAGTCAAAGAGGCCAAAGTACAGAGAGCTGCTGAAGCATCCGTTTATCCTGATGTACGAGGAGCGTCTGGTGGACGTGGCCCGATACGTGTGCCGGATCCTGGACCAGATGCCGGCGTCCCCCGGCTCTCCCATGTATGTGGACTGATGGAGAACGGCATTCTGGGTAACGGAGTCCTGTGGCGTCCACGCATCACTGCCCGCTGACCTGAGAGTGCGAAGATCCAGAGCAAACCAGGGCACAGGGTCTGACACGGGAGCGctggtctca

Function

symbol description
map2k4b Predicted to enable JUN kinase kinase activity. Acts upstream of or within convergent extension involved in gastrulation. Human ortholog(s) of this gene implicated in ovarian serous carcinoma; pancreatic cancer; and urinary bladder cancer. Orthologous to human MAP2K4 (mitogen-activated protein kinase kinase 4).

GO:

id name namespace
GO:0007257 activation of JUN kinase activity biological_process
GO:0006468 protein phosphorylation biological_process
GO:0000187 activation of MAPK activity biological_process
GO:0016310 phosphorylation biological_process
GO:0060027 convergent extension involved in gastrulation biological_process
GO:0016740 transferase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0008545 JUN kinase kinase activity molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function
GO:0016301 kinase activity molecular_function
GO:0004708 MAP kinase kinase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-080721-13 Predicted to enable JUN kinase kinase activity. Acts upstream of or within convergent extension involved in gastrulation. Human ortholog(s) of this gene implicated in ovarian serous carcinoma; pancreatic cancer; and urinary bladder cancer. Orthologous to human MAP2K4 (mitogen-activated protein kinase kinase 4).

Ensembl:

ensembl_id ENSDARG00000077177

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00009819 True 1578 mRNA 0.57 13 281166 287633

Neighbor

gene id symbol gene type direction distance location
XLOC_005037 NA coding downstream 1831 250081 ~ 279335 (-)
XLOC_005038 NA coding downstream 15965 262396 ~ 265201 (-)
XLOC_005036 CABZ01102039.1 coding downstream 68323 204095 ~ 212843 (-)
XLOC_005035 NA coding downstream 100357 180200 ~ 180809 (-)
XLOC_005034 NA coding downstream 105647 171286 ~ 175519 (-)
XLOC_005040 adprm coding upstream 475 288108 ~ 290815 (-)
XLOC_005041 pts coding upstream 24815 312448 ~ 314899 (-)
XLOC_005042 NA coding upstream 50175 337808 ~ 355555 (-)
XLOC_005043 NA coding upstream 118554 406187 ~ 408631 (-)
XLOC_005044 hs3st3l coding upstream 128078 415711 ~ 431249 (-)
XLOC_005031 NA non-coding downstream 215406 64267 ~ 65760 (-)
XLOC_005057 NA non-coding upstream 784852 1072485 ~ 1085227 (-)
XLOC_005062 NA non-coding upstream 1165267 1452900 ~ 1453339 (-)
XLOC_005063 CU694266.1 non-coding upstream 1202839 1490472 ~ 1490588 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000047_07119977_07126126 MAP2K4B, MAP2K4 coding CI01000047 null 7119977 ~ 7128054 (+)